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Research Article

In vitro skin permeation and decontamination of the organophosphorus pesticide paraoxon under various physical conditions – evidence for a wash-in effect

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Pages 520-525 | Received 08 Feb 2012, Accepted 06 Apr 2012, Published online: 23 May 2012

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Read on this site (6)

Thomas James, Lydia Izon-Cooper, Samuel Collins, Haydn Cole & Tim Marczylo. (2022) The wash-in effect and its significance for mass casualty decontamination. Journal of Toxicology and Environmental Health, Part B 25:3, pages 113-134.
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Lina Thors, Elisabeth Wigenstam, Johanna Qvarnström & Anders Bucht. (2021) Efficient agent degradation within skin is important for decontamination of percutaneously exposed VX. Cutaneous and Ocular Toxicology 40:2, pages 95-102.
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Emma Forsberg, Linda Öberg, Elisabet Artursson, Elisabeth Wigenstam, Anders Bucht & Lina Thors. (2020) Decontamination efficacy of soapy water and water washing following exposure of toxic chemicals on human skin. Cutaneous and Ocular Toxicology 39:2, pages 134-142.
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Ruzena Pavlikova, Jan Misik, Jiri Cabal, Jan Marek & Kamil Kuca. (2018) In vitro skin decontamination of paraoxon – wet-type cleansing effect of selected detergents. Cutaneous and Ocular Toxicology 37:1, pages 77-83.
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Hazem Matar, Antonio Guerreiro, Sergey A. Piletsky, Shirley C. Price & Robert P. Chilcott. (2016) Preliminary evaluation of military, commercial and novel skin decontamination products against a chemical warfare agent simulant (methyl salicylate). Cutaneous and Ocular Toxicology 35:2, pages 137-144.
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Jan Misik, Michal Pavlik, Ladislav Novotny, Ruzena Pavlikova, Robert P. Chilcott, Jiri Cabal & Kamil Kuca. (2012) In vivo decontamination of the nerve agent VX using the domestic swine model. Clinical Toxicology 50:9, pages 807-811.
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Articles from other publishers (18)

Jayme Cannon, Shengzhuang Tang, Kelly Yang, Racquel Harrison & Seok Ki Choi. (2021) Dual acting oximes designed for therapeutic decontamination of reactive organophosphates via catalytic inactivation and acetylcholinesterase reactivation . RSC Medicinal Chemistry 12:9, pages 1592-1603.
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Samuel Collins, Thomas James, Holly Carter, Charles Symons, Felicity Southworth, Kerry Foxall, Tim Marczylo & Richard Amlôt. (2021) Mass Casualty Decontamination for Chemical Incidents: Research Outcomes and Future Priorities. International Journal of Environmental Research and Public Health 18:6, pages 3079.
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Seok Ki Choi. (2021) Nanomaterial-Enabled Sensors and Therapeutic Platforms for Reactive Organophosphates. Nanomaterials 11:1, pages 224.
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Denis Josse. 2020. Skin Decontamination. Skin Decontamination 77 85 .
Christina Phuong & Howard I. Maibach. 2020. Skin Decontamination. Skin Decontamination 45 51 .
Robert P. Chilcott, Joanne Larner, Adam Durrant, Philip Hughes, Devanya Mahalingam, Samantha Rivers, Elliot Thomas, Nevine Amer, Mark Barrett, Hazem Matar, Andreia Pinhal, Toni Jackson, Kate McCarthy-Barnett & Joseph Reppucci. (2019) Evaluation of US Federal Guidelines (Primary Response Incident Scene Management [PRISM]) for Mass Decontamination of Casualties During the Initial Operational Response to a Chemical Incident. Annals of Emergency Medicine 73:6, pages 671-684.
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Pamela T. Wong, Somnath Bhattacharjee, Jayme Cannon, Shengzhuang Tang, Kelly Yang, Sierra Bowden, Victoria Varnau, Jessica J. O'Konek & Seok Ki Choi. (2019) Reactivity and mechanism of α-nucleophile scaffolds as catalytic organophosphate scavengers. Organic & Biomolecular Chemistry 17:16, pages 3951-3963.
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Shengzhuang Tang, Pamela T. Wong, Jayme Cannon, Kelly Yang, Sierra Bowden, Somnath Bhattacharjee, Jessica J. O'Konek & Seok Ki Choi. (2019) Hydrophilic scaffolds of oxime as the potent catalytic inactivator of reactive organophosphate. Chemico-Biological Interactions 297, pages 67-79.
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L. Thors, S. Lindberg, S. Johansson, B. Koch, M. Koch, L. H?gglund & A. Bucht. (2017) RSDL decontamination of human skin contaminated with the nerve agent VX. Toxicology Letters 269, pages 47-54.
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Nick Kassouf, Sara Syed, Joanne Larner, Richard Amlôt & Robert P. Chilcott. (2017) Evaluation of absorbent materials for use as ad hoc dry decontaminants during mass casualty incidents as part of the UK’s Initial Operational Response (IOR). PLOS ONE 12:2, pages e0170966.
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Christina Phuong & Howard I. Maibach. (2016) Recent knowledge: Concepts of dermal absorption in relation to skin decontamination. Journal of Applied Toxicology 36:1, pages 5-9.
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Kathrin Dennerlein, Thomas Jäger, Thomas Göen, Sonja Kilo, Karl Heinz Schaller, Hans Drexler & Gintautas Korinth. (2015) Evaluation of the effect of skin cleaning procedures on the dermal absorption of chemicals. Toxicology in Vitro 29:5, pages 828-833.
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R. Duarte-Davidson, R. Orford, S. Wyke, M. Griffiths, R. Amlôt & R. Chilcott. (2014) Recent advances to address European Union Health Security from cross border chemical health threats. Environment International 72, pages 3-14.
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H. Matar, J. Larner, S. Kansagra, K.L. Atkinson, J.T. Skamarauskas, R. Amlot & R.P. Chilcott. (2014) Design and characterisation of a novel in vitro skin diffusion cell system for assessing mass casualty decontamination systems. Toxicology in Vitro 28:4, pages 492-501.
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François Burgher, Laurence Mathieu, Joël Blomet, Sarah J. Gilpin, Howard I. Maibach, Aziza Whaby, Alan H. Hall, Maral Rhavar, Xiaoying Hui, Denise Jacquemin, Maurizio Cavallini, Carlos Alberto Yoshimura & Heidi P. Chan. 2014. Chemical Skin Injury. Chemical Skin Injury 73 196 .
Robert P. Chilcott. 2014. Topical Drug Bioavailability, Bioequivalence, and Penetration. Topical Drug Bioavailability, Bioequivalence, and Penetration 41 57 .
Tong Wu, Wenting Zhao, Zhonghua Yang, Haixiang Gao & Zhiqiang Zhou. (2013) Temperature-controlled ultrasound- and vortex-assisted liquid-liquid microextraction combined with GC for the determination of the concentrations of organophosphorus pesticides in beverage samples. Journal of Separation Science 36:24, pages 3918-3925.
Crossref
Jan Misík, Růžena Pavlíková, Jiří Cabal, Denis Josse & Kamil Kuča. (2012) IN VITRO SKIN PERMEATION OF DETERGENTS AND DETERGENT-BASED DECONTAMINATION MIXTURE. Military Medical Science Letters 81:3, pages 96-99.
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