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Research Article

Safety, efficacy and toxicological evaluation of a novel, patented anti-diabetic extract of Trigonella Foenum-Graecum seed extract (Fenfuro)

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Pages 495-503 | Received 29 May 2014, Accepted 28 Jun 2014, Published online: 11 Sep 2014

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Debasish Hota, Biswa M. Padhy, Rituparna Maiti, Debasis Bisoi, Jyoti Prakash Sahoo, Binod K. Patro, Pawan Kumar, Apurva Goel, Samudra P. Banik, Sanjoy Chakraborty, Mehul Rungta, Manashi Bagchi & Debasis Bagchi. (2023) A Placebo-Controlled, Double-Blind Clinical Investigation to Evaluate the Efficacy of a Patented Trigonella foenum-graecum Seed Extract “Fenfuro®” in Type 2 Diabetics. Journal of the American Nutrition Association 0:0, pages 1-10.
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S. N. Sankhwar, Pawan Kumar, Manashi Bagchi, Mehul Rungta & Debasis Bagchi. (2023) Safety and Efficacy of Furosap®, a Patented Trigonella foenum-graecum Seed Extract, in Boosting Testosterone Level, Reproductive Health and Mood Alleviation in Male Volunteers. Journal of the American Nutrition Association 42:1, pages 27-35.
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Narsingh Verma, Kauser Usman, Naresh Patel, Arvind Jain, Sudhir Dhakre, Anand Swaroop, Manashi Bagchi, Pawan Kumar, Harry G. Preuss & Debasis Bagchi. (2016) A multicenter clinical study to determine the efficacy of a novel fenugreek seed (Trigonella foenum-graecum) extract (Fenfuro™) in patients with type 2 diabetes. Food & Nutrition Research 60:1.
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Imad Ahmad, Aleksey E. Kuznetsov, Abdul Saboor Pirzada, Khalaf F. Alsharif, Maria Daglia & Haroon Khan. (2023) Computational pharmacology and computational chemistry of 4-hydroxyisoleucine: Physicochemical, pharmacokinetic, and DFT-based approaches. Frontiers in Chemistry 11.
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Neetu Singh, Surender Singh Yadav, Sanjiv Kumar & Balasubramaniam Narashiman. (2022) Ethnopharmacological, phytochemical and clinical studies on Fenugreek (Trigonella foenum-graecum L.). Food Bioscience 46, pages 101546.
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Uma Maheshwari Srinivasa & Madeneni Madhava Naidu. 2021. 141 184 .
Ayah Rebhi Hilles & Syed Mahmood. 2021. Fenugreek. Fenugreek 503 522 .
Shikha Dixit & Sugandha Tiwari. (2020) Investigation of anti-diabetic plants used among the ethnic communities of Kanpur division, India. Journal of Ethnopharmacology 253, pages 112639.
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Amit D. Kandhare, Prasad A. Thakurdesai, Pralhad Wangikar & Subhash L. Bodhankar. (2019) A systematic literature review of fenugreek seed toxicity by using ToxRTool: evidence from preclinical and clinical studies. Heliyon 5:4, pages e01536.
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Solomon Habtemariam. 2019. Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases. Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases 579 637 .
Miriam G. Shtriker, Irena Peri, Elise Taieb, Abraham Nyska, Oren Tirosh & Zecharia Madar. (2018) Galactomannan More than Pectin Exacerbates Liver Injury in Mice Fed with High‐Fat, High‐Cholesterol Diet. Molecular Nutrition & Food Research 62:20.
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Rajnish Gupta. (2018) Active phytoconstituents for diabetes management: A review. Journal of Complementary and Integrative Medicine 15:3.
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Anand Swaroop, Manashi Bagchi, Harry G. Preuss & Debasis Bagchi. 2018. Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome. Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome 357 364 .
Mubashrah Munir & Rahmatullah Qureshi. 2018. Plant and Human Health, Volume 1. Plant and Human Health, Volume 1 463 545 .
A. Demmers, H. Korthout, F.S. van Etten-Jamaludin, F. Kortekaas & J.M. Maaskant. (2017) Effects of medicinal food plants on impaired glucose tolerance: A systematic review of randomized controlled trials. Diabetes Research and Clinical Practice 131, pages 91-106.
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Jorge M. Alves-Silva, Abderrahmane Romane, Thomas Efferth & Lígia Salgueiro. (2017) North African Medicinal Plants Traditionally Used in Cancer Therapy. Frontiers in Pharmacology 8.
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Kalyan C. Nagulapalli Venkata, Anand Swaroop, Debasis Bagchi & Anupam Bishayee. (2017) A small plant with big benefits: Fenugreek ( Trigonella foenum-graecum Linn.) for disease prevention and health promotion . Molecular Nutrition & Food Research 61:6, pages 1600950.
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Keith W. Singletary. (2017) Fenugreek. Nutrition Today 52:2, pages 93-111.
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Mounir Ouzir, Khalid El Bairi & Saaïd Amzazi. (2016) Toxicological properties of fenugreek (Trigonella foenum graecum). Food and Chemical Toxicology 96, pages 145-154.
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Manoj Goyal. (2015) Traditional plants used for the treatment of diabetes mellitus in Sursagar constituency, Jodhpur, Rajasthan – An ethnomedicinal survey. Journal of Ethnopharmacology 174, pages 364-368.
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Ghulam Yaseen, Mushtaq Ahmad, Muhammad Zafar, Shazia Sultana, Sadaf Kayani, Adolfo Andrade Cetto & Shabnum Shaheen. (2015) Traditional management of diabetes in Pakistan: Ethnobotanical investigation from Traditional Health Practitioners. Journal of Ethnopharmacology 174, pages 91-117.
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Yinan Hua, Sidney Y. Ren, Rui Guo, Olivia Rogers, Rama P. Nair, Debasis Bagchi, Anand Swaroop & Sreejayan Nair. (2015) Furostanolic saponins from Trigonella foenum-graecum alleviate diet-induced glucose intolerance and hepatic fat accumulation . Molecular Nutrition & Food Research 59:10, pages 2094-2100.
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