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Original Article

Mechanical Stimulation of Gap Junctions in Bone Osteocytes is Mediated by Prostaglandin E2

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Pages 283-288 | Received 01 Sep 2001, Accepted 15 Sep 2001, Published online: 11 Jul 2009

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Jean X. Jiang & Priscilla P. Cherian. (2003) Hemichannels Formed by Connexin 43 Play an Important Role in the Release of Prostaglandin E2by Osteocytes in Response to Mechanical Strain. Cell Communication & Adhesion 10:4-6, pages 259-264.
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Yan Zeng, Manuel A. Riquelme, Rui Hua, Jingruo Zhang, Francisca M. Acosta, Sumin Gu & Jean X. Jiang. (2022) Mechanosensitive piezo1 calcium channel activates connexin 43 hemichannels through PI3K signaling pathway in bone. Cell & Bioscience 12:1.
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Shane A Lloyd, Alayna E Loiselle, Yue Zhang & Henry J Donahue. (2014) Shifting Paradigms on the Role of Connexin43 in the Skeletal Response to Mechanical Load. Journal of Bone and Mineral Research 29:2, pages 275-286.
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Alayna E. Loiselle, Jean X. Jiang & Henry J. Donahue. (2013) Gap junction and hemichannel functions in osteocytes. Bone 54:2, pages 205-212.
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Suzanne M. Ponik, Jason W. Triplett & Fredrick M. Pavalko. (2006) Osteoblasts and osteocytes respond differently to oscillatory and unidirectional fluid flow profiles. Journal of Cellular Biochemistry 100:3, pages 794-807.
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Adam M. Sorkin, Kay C. Dee & Melissa L. Knothe Tate. (2004) “Culture shock” from the bone cell's perspective: emulating physiological conditions for mechanobiological investigations. American Journal of Physiology-Cell Physiology 287:6, pages C1527-C1536.
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Terhi J Heino, Teuvo A Hentunen & H.Kalervo Väänänen. (2004) Conditioned medium from osteocytes stimulates the proliferation of bone marrow mesenchymal stem cells and their differentiation into osteoblasts. Experimental Cell Research 294:2, pages 458-468.
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