2,841
Views
31
CrossRef citations to date
0
Altmetric
Research Article

Effects of thymol and carvacrol on T-helper cell subset cytokines and their main transcription factors in ovalbumin-immunized mice

&
Pages 729-737 | Received 20 Jan 2016, Accepted 29 Mar 2016, Published online: 14 Jul 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Maryam Bayat, Kurosh Kalantar & Zahra Amirghofran. (2019) Inhibition of interferon-γ production and T-bet expression by menthol treatment of human peripheral blood mononuclear cells. Immunopharmacology and Immunotoxicology 41:2, pages 267-276.
Read now

Articles from other publishers (30)

Mahdieh Ahmadi, Akram Eidi, Hassan Ahmadvand, Mojtaba Khaksarian & Fattah Sotoodehnejadnematalahi. (2023) Effect of Carvacrol on histological analysis and expression of genes involved in an animal model of multiple sclerosis. Multiple Sclerosis and Related Disorders 70, pages 104471.
Crossref
Sirajunnisa Abdul Razack, Yeachan Lee, Hwarang Shin, Surendhiran Duraiarasan, Byung-Soo Chun & Hyun Wook Kang. (2023) Cellulose nanofibrils reinforced chitosan-gelatin based hydrogel loaded with nanoemulsion of oregano essential oil for diabetic wound healing assisted by low level laser therapy. International Journal of Biological Macromolecules 226, pages 220-239.
Crossref
Fatemeh Vazirian, Sara Samadi, Mohammadreza Abbaspour, Amirmahdi Taleb, Hadi Bagherhosseini, Hooman Mosannen Mozaffari, Amir Hooshang Mohammadpour & Seyed Ahmad Emami. (2022) Evaluation of the efficacy of Thymus kotschyanus extract as an additive treatment in patients with ulcerative colitis: a randomized double-blind placebo-controlled trial. Inflammopharmacology 30:6, pages 2145-2152.
Crossref
Amira M. Badr, Layla A. Alkharashi, Iman O. Sherif, Alaa A. Alanteet, Hind N. Alotaibi & Yasmen F. Mahran. (2022) IL-17/Notch1/STAT3 Pathway Contributes to 5-Fluorouracil-Induced Intestinal Mucositis in Rats: Amelioration by Thymol Treatment. Pharmaceuticals 15:11, pages 1412.
Crossref
Yao Liu, Hui Yan, Bing Yu, Jun He, Xiangbing Mao, Jie Yu, Ping Zheng, Zhiqing Huang, Yuheng Luo, Junqiu Luo, Aimin Wu & Daiwen Chen. (2022) Protective Effects of Natural Antioxidants on Inflammatory Bowel Disease: Thymol and Its Pharmacological Properties. Antioxidants 11:10, pages 1947.
Crossref
Mahammad R. Khazdair, Vahideh Ghorani & Mohammad H. Boskabady. (2022) Experimental and clinical evidence on the effect of carvacrol on respiratory, allergic, and immunologic disorders: A comprehensive review. BioFactors 48:4, pages 779-794.
Crossref
Mahdeiah Ahmadi, Akram Eidi, Hassan Ahmadvand, Mojtaba Khaksarian & Fattah Sotoodehnejadnematalahi. (2022) The Effect of Carvacrol on the Expression of Genes Hmox-1, iNOS, Nrf2 and NF-ҚB in the Spinal Cord of Experimental Autoimmune Encephalomyelitis Mice. Iranian South Medical Journal 25:1, pages 1-12.
Crossref
Osama M. Ahmed, Sanaa R. Galaly, Mennah-Allah M. A. Mostafa, Emad M. Eed, Tarek M. Ali, Alzhraa M. Fahmy & Mohamed Y. Zaky. (2022) Thyme Oil and Thymol Counter Doxorubicin-Induced Hepatotoxicity via Modulation of Inflammation, Apoptosis, and Oxidative Stress. Oxidative Medicine and Cellular Longevity 2022, pages 1-19.
Crossref
Mohammad Hossein Boskabady, Mohammad Reza Khazdair, Arghavan Memarzia & Seyyedeh Zahra Ghasemi. 2022. Herbal Biomolecules in Healthcare Applications. Herbal Biomolecules in Healthcare Applications 551 572 .
Paula Mendonça Leite, Juliana Mendes Amorim & Rachel Oliveira Castilho. 2022. Plants and Phytomolecules for Immunomodulation. Plants and Phytomolecules for Immunomodulation 321 360 .
Layla A. Al‐Khrashi, Amira M. Badr, Maha A. AL‐Amin & Yasmen F. Mahran. (2021) Thymol ameliorates 5‐fluorouracil‐induced intestinal mucositis: Evidence of down‐regulatory effect on TGF‐β/MAPK pathways through NF‐κB. Journal of Biochemical and Molecular Toxicology 36:1.
Crossref
Mohammad Reza Khazdair, Zahra Gholamnezhad, Ramin Rezaee & Mohammad Hossein Boskabady. (2021) Immuno-modulatory and anti-inflammatory effects of Thymus vulgaris, Zataria multiflora, and Portulaca oleracea and their constituents. Pharmacological Research - Modern Chinese Medicine 1, pages 100010.
Crossref
Omid Yazarlu, Mehrdad Iranshahi, Hamid Reza Khayat Kashani, Sara Reshadat, Solomon Habtemariam, Milad Iranshahy & Maede Hasanpour. (2021) Perspective on the application of medicinal plants and natural products in wound healing: A mechanistic review. Pharmacological Research 174, pages 105841.
Crossref
Mohammad Reza Khazdair & Mohammad Hossein Boskabady. (2021) Possible treatment with medicinal herbs and their ingredients of lung disorders induced by sulfur mustard exposures: a review. Environmental Science and Pollution Research 28:39, pages 54191-54208.
Crossref
Yamixa Delgado, Céline Cassé, Yancy Ferrer-Acosta, Ivette J. Suárez-Arroyo, José Rodríguez-Zayas, Anamaris Torres, Zally Torres-Martínez, Daraishka Pérez, Michael J. González, Ricardo A. Velázquez-Aponte, Josué Andino, Clarissa Correa-Rodríguez, Jean C. Franco, Wandaliz Milán, Gabriela Rosario, Eddian Velázquez, Jaisy Vega, Janmary Colón & Christopher Batista. (2021) Biomedical Effects of the Phytonutrients Turmeric, Garlic, Cinnamon, Graviola, and Oregano: A Comprehensive Review. Applied Sciences 11:18, pages 8477.
Crossref
Amanda Gabrielle Barros Dantas, Rafael Limongi de Souza, Anderson Rodrigues de Almeida, Francisco Humberto Xavier Júnior, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo & Elquio Eleamen Oliveira. (2021) Development, Characterization, and Immunomodulatory Evaluation of Carvacrol-loaded Nanoemulsion. Molecules 26:13, pages 3899.
Crossref
Saeideh Saadat, Mohammad Reza Aslani, Vahideh Ghorani, Rana Keyhanmanesh & Mohammad Hossein Boskabady. (2021) The effects of Nigella sativa on respiratory, allergic and immunologic disorders, evidence from experimental and clinical studies, a comprehensive and updated review . Phytotherapy Research 35:6, pages 2968-2996.
Crossref
Vahideh Ghorani, Azam Alavinezhad, Omid Rajabi & Mohammad Hossein Boskabady. (2021) Carvacrol improves pulmonary function tests, oxidant/antioxidant parameters and cytokine levels in asthmatic patients: A randomized, double-blind, clinical trial. Phytomedicine 85, pages 153539.
Crossref
Hayate Javed, Mohamed Fizur Nagoor Meeran, Niraj Kumar Jha & Shreesh Ojha. (2021) Carvacrol, a Plant Metabolite Targeting Viral Protease (Mpro) and ACE2 in Host Cells Can Be a Possible Candidate for COVID-19. Frontiers in Plant Science 11.
Crossref
Yousra M. Ezz-Eldin, Ali A. Aboseif & Marwa M. Khalaf. (2020) Potential anti-inflammatory and immunomodulatory effects of carvacrol against ovalbumin-induced asthma in rats. Life Sciences 242, pages 117222.
Crossref
Sara Golbahari & Seyyed Meysam Abtahi Froushani. (2019) Synergistic benefits of Nicotine and Thymol in alleviating experimental rheumatoid arthritis. Life Sciences 239, pages 117037.
Crossref
Fatima Bouhtit, Mehdi Najar, Douâa Moussa Agha, Rahma Melki, Mustapha Najimi, Khalid Sadki, Philippe Lewalle, Abdellah Hamal, Laurence Lagneaux & Makram Merimi. (2019) The biological response of mesenchymal stromal cells to thymol and carvacrol in comparison to their essential oil: An innovative new study. Food and Chemical Toxicology 134, pages 110844.
Crossref
Lee Yen Sim, Nur Zahirah Abd Rani & Khairana Husain. (2019) Lamiaceae: An Insight on Their Anti-Allergic Potential and Its Mechanisms of Action. Frontiers in Pharmacology 10.
Crossref
Majid Kianmehr, Abdolrahim Rezaee, Mahmoud Mahmoudi, Vahideh Ghorani & Mohammad Hossein Boskabady. (2018) T helper cells subtypes and their cytokine gene expression affected by carvacrol in sensitized mice administered during sensitization period. Journal of Cellular Biochemistry 120:4, pages 5343-5354.
Crossref
Merat Mahmoodi, Houshang Amiri, Fatemeh Ayoobi, Mehdi Rahmani, Zahra Taghipour, Razieh Taghizadeh Ghavamabadi, Abdollah Jafarzadeh & Mojtaba Sankian. (2019) Carvacrol ameliorates experimental autoimmune encephalomyelitis through modulating pro- and anti-inflammatory cytokines. Life Sciences 219, pages 257-263.
Crossref
Haideh Namdari, Maryam Izad, Farhad Rezaei & Zahra Amirghofran. (2019) Thymol as a reciprocal regulator of T cell differentiation: Promotion of regulatory T cells and suppression of Th1/Th17 cells. International Immunopharmacology 67, pages 417-426.
Crossref
Michelle Fonseca Costa, Aimée Obolari Durço, Thallita Kelly Rabelo, Rosana de Souza Siqueira Barreto & Adriana Gibara Guimarães. (2019) Effects of Carvacrol, Thymol and essential oils containing such monoterpenes on wound healing: a systematic review. Journal of Pharmacy and Pharmacology 71:2, pages 141-155.
Crossref
Merat Mahmoodi, Fatemeh Ayoobi, Azita Aghaei, Mehdi Rahmani, Zahra Taghipour, Azar Hosseini, Abdollah Jafarzadeh & Mojtaba Sankian. (2019) Beneficial effects of Thymus vulgaris extract in experimental autoimmune encephalomyelitis: Clinical, histological and cytokine alterations. Biomedicine & Pharmacotherapy 109, pages 2100-2108.
Crossref
Mohamed Fizur Nagoor Meeran, Hayate Javed, Hasan Al Taee, Sheikh Azimullah & Shreesh K. Ojha. (2017) Pharmacological Properties and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical Development. Frontiers in Pharmacology 8.
Crossref
Zhigang Wang, Tao Chen, Man Long, Longyun Chen, Lei Wang, Nina Yin & Zebin Chen. (2016) Electro-acupuncture at Acupoint ST36 Ameliorates Inflammation and Regulates Th1/Th2 Balance in Delayed-Type Hypersensitivity. Inflammation 40:2, pages 422-434.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.