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Review Article

Necrotizing Enterocolitis: A Review of Pathogenetic Mechanisms and Implications for Prevention

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Pages 357-369 | Received 07 Oct 1992, Accepted 30 Nov 1992, Published online: 09 Jul 2009

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Rose M. Viscardi, Nancy H. Lyon, Chen-Chih J. Sun, J. Richard Hebel & Jeffrey D. Hasday. (1997) Inflammatory Cytokine mRNAs in Surgical Specimens of Necrotizing Enterocolitis and Normal Newborn Intestine. Pediatric Pathology & Laboratory Medicine 17:4, pages 547-559.
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Michael S. Caplan, Eric Hedlund, Luba Adler & Wei Hsueh. (1994) Role of Asphyxia and Feeding in a Neonatal Rat Model of Necrotizing Enterocolitis. Pediatric Pathology 14:6, pages 1017-1028.
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Articles from other publishers (75)

Osnat Zmora, Ola Gutzeit, Linoy Segal, Sari Boulos, Zvika Millo, Yuval Ginsberg, Nizar Khatib, Ofer Fainaru, Michael G. Ross, Zeev Weiner & Ron Beloosesky. (2021) Maternal N‐acetyl‐cysteine prevents neonatal brain injury associated with necrotizing enterocolitis in a rat model. Acta Obstetricia et Gynecologica Scandinavica 100:5, pages 979-987.
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Osnat Zmora, Ola Gutzeit, Linoy Segal, Sari Boulos, Zvika Millo, Yuval Ginsberg, Nizar Khatib, Fadwa Dabbah-Assad, Ofer Fainaru, Zeev Weiner & Ron Beloosesky. (2020) Prophylactic antenatal N-Acetyl Cysteine administration combined with postnatal administration can decrease mortality and injury markers associated with necrotizing enterocolitis in a rat model. PLOS ONE 15:6, pages e0233612.
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David J. Hackam & Chhinder P. Sodhi. (2018) Toll-Like Receptor–Mediated Intestinal Inflammatory Imbalance in the Pathogenesis of Necrotizing Enterocolitis. Cellular and Molecular Gastroenterology and Hepatology 6:2, pages 229-238.e1.
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Shin Shinyama, Tatsuru Kaji, Motoi Mukai, Kazuhiko Nakame, Hiroshi Matsufuji, Hideo Takamatsu & Satoshi Ieiri. (2017) The novel preventive effect of Daikenchuto (TJ-100), a Japanese herbal drug, against neonatal necrotizing enterocolitis in rats. Pediatric Surgery International 33:10, pages 1109-1114.
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Kazuhiko Nakame, Tatsuru Kaji, Motoi Mukai, Shin Shinyama & Hiroshi Matsufuji. (2016) The protective and anti-inflammatory effects of glucagon-like peptide-2 in an experimental rat model of necrotizing enterocolitis. Peptides 75, pages 1-7.
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Roberto Murgas Torrazza, Nan Li & Josef Neu. (2014) Decoding the enigma of necrotizing enterocolitis in premature infants. Pathophysiology 21:1, pages 21-27.
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Sadık Yurttutan, Ramazan Ozdemir, Fuat Emre Canpolat, Mehmet Yekta Oncel, Hatice Germen Unverdi, Bülent Uysal, Ömer Erdeve & Ugur Dilmen. (2013) Beneficial effects of Etanercept on experimental necrotizing enterocolitis. Pediatric Surgery International 30:1, pages 71-77.
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Jiliu Xu, Virginia Anderson & Steven M. Schwarz. (2013) Dietary GD3 Ganglioside Reduces the Incidence and Severity of Necrotizing Enterocolitis by Sustaining Regulatory Immune Responses. Journal of Pediatric Gastroenterology & Nutrition 57:5, pages 550-556.
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Sheng-Ru Shiou, Yueyue Yu, Yuee Guo, Shu-Mei He, C. Haikaeli Mziray-Andrew, Jeanette Hoenig, Jun Sun, Elaine O. Petrof & Erika C. Claud. (2013) Synergistic Protection of Combined Probiotic Conditioned Media against Neonatal Necrotizing Enterocolitis-Like Intestinal Injury. PLoS ONE 8:5, pages e65108.
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Roberto Murgas Torrazza & Josef Neu. (2013) The Altered Gut Microbiome and Necrotizing Enterocolitis. Clinics in Perinatology 40:1, pages 93-108.
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Dilek Dilli, Zeynep Eras, Hülya Özkan Ulu, Uğur Dilmen & Evrim Durgut Şakrucu. (2012) Does necrotizing enterocolitis affect growth and neurodevelopmental outcome in very low birth weight infants?. Pediatric Surgery International 28:5, pages 471-476.
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Stephanie SchulzHui ZhaoRonald J. WongDavid K. Stevenson. (2012) Heme Oxygenase Biology: Part 2: Neonatal Disorders. NeoReviews 13:3, pages e158-e165.
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Jiliu Xu, William R Treem, Christopher Roman, Virginia Anderson, Richard Rubenstein & Steven M Schwarz. (2011) Ileal Immune Dysregulation in Necrotizing Enterocolitis: Role of CD40/CD40L in the Pathogenesis of Disease. Journal of Pediatric Gastroenterology & Nutrition 52:2, pages 140-146.
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Jessica A. Dominguez. (2010) Use of Minimal Enteral Nutrition to Prevent Necrotizing Enterocolitis. Journal of Parenteral and Enteral Nutrition 35:1, pages 14-15.
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M S Caplan. (2009) Probiotic and prebiotic supplementation for the prevention of neonatal necrotizing enterocolitis. Journal of Perinatology 29:S2, pages S2-S6.
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Melissa D. Halpern & Bohuslav Dvorak. (2008) Does Abnormal Bile Acid Metabolism Contribute to NEC?. Seminars in Perinatology 32:2, pages 114-121.
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