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Clinical Toxicology Volume 48, 2010 - Issue 8
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Bioscavenger therapy for organophosphate poisoning – an open-labeled pilot randomized trial comparing fresh frozen plasma or albumin with saline in acute organophosphate poisoning in humans

Kishore Pichamuthu Medical Intensive Care Unit
,
Jayakumar Jerobin Medical Intensive Care Unit
,
Anupama Nair Medical Intensive Care Unit
,
George John Medical Intensive Care Unit
,
Joseph Kamalesh Department of Emergency Medicine
,
Kurien Thomas Department of Medicine
,
Arun Jose Department of Clinical Biochemistry
,
Jude Joseph Fleming Department of Clinical Biochemistry
,
Anand Zachariah Department of Medicine
,
Suresh S. David Department of Emergency Medicine
,
Dolly Daniel Department of Clinical Pathology and Transfusion Medicine, Christian Medical College and Hospital, Vellore, India
&
John Victor Peter Medical Intensive Care UnitCorrespondence[email protected]
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Pages 813-819 | Received 13 May 2010, Accepted 24 Aug 2010, Published online: 06 Oct 2010

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Farzad Gheshlaghi, Mahsa Akafzadeh Savari, Rozita Nasiri, Anselm Wong, Awat Feizi, Mohammad Reza Maracy, Gholamali Dorooshi, Rokhsareh Meamar & Nastaran Eizadi-Mood. (2020) Efficacy of fresh frozen plasma transfusion in comparison with conventional regimen in organophosphate poisoning treatment: a meta-analysis study. Critical Reviews in Toxicology 50:8, pages 677-684.
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John Victor Peter, Jayakumar Jerobin, Anupama Nair, Anjana Bennett, Prasanna Samuel, Anugrah Chrispal, Ooriapadickal Cherian Abraham, Kuruvilla Prasad Mathews, Jude Joseph Fleming & Anna Oommen. (2010) Clinical profile and outcome of patients hospitalized with dimethyl and diethyl organophosphate poisoning. Clinical Toxicology 48:9, pages 916-923.
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Articles from other publishers (19)

Michael Eddleston, John Victor Peter, Ramya Iyyadurai, Jude Joseph Fleming, Kundavaram Paul Prabhakar Abhilash, Audrin Lenin, Vignesh Kumar Chandiraseharan, Asisha Janeela Mathansingh, Arun Jose, Samuel George Hansdak, Thenmozhi Mani & Anand Zachariah. (2023) Quantification of Organophosphorus Insecticide Removed by Gastric Lavage in Acutely Poisoned Patients: An Observational Study. Indian Journal of Critical Care Medicine 27:6, pages 397-402.
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Giuliano Pasquale Ramadori. (2023) Organophosphorus Poisoning: Acute Respiratory Distress Syndrome (ARDS) and Cardiac Failure as Cause of Death in Hospitalized Patients. International Journal of Molecular Sciences 24:7, pages 6658.
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Vladislav E. Sobolev, Margarita O. Sokolova, Richard O. Jenkins & Nikolay V. Goncharov. (2022) Molecular Mechanisms of Acute Organophosphate Nephrotoxicity. International Journal of Molecular Sciences 23:16, pages 8855.
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Nidhi Kaeley, Ankita Kabi, Hari Prasad, Alok Raj & Anirban Ghosh Hazra. (2022) Pneumothorax and Pneumomediastinum Complicating Organophosphate Poisoning: A Case Series of Complications Less Understood. Cureus.
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Eul Noh, Jeong Mi Moon, Byeong Jo Chun, Yong Soo Cho, SeokJin Ryu & Dongki Kim. (2020) The clinical role of serum albumin in Organophospate poisoning. Basic & Clinical Pharmacology & Toxicology 128:4, pages 605-614.
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Saeed Afzali, Manoochehr Karami, Nejat Kheyripour & Akram Ranjbar. (2020) Investigating the Effect of Fresh Frozen Plasma and Albumin on DNA Damage and Oxidative Stress Biomarkers in Poisoning Cases by Organophosphates. Drug Research 71:01, pages 10-16.
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N. Amend, J. Langgartner, M. Siegert, T. Kranawetvogl, M. Koller, H. John, C. Pflügler, C. Mögele-Schmid, F. Worek, H. Thiermann & T. Wille. (2020) A case report of cholinesterase inhibitor poisoning: cholinesterase activities and analytical methods for diagnosis and clinical decision making. Archives of Toxicology 94:6, pages 2239-2247.
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. (2019) Antidotes in Poisoning. Indian Journal of Critical Care Medicine 23:S4, pages 0-0.
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Osman Yesilbas, Hasan S. Kihtir, Mohammad Altiti, Mey Talip Petmezci, Seda Balkaya, Burcu Bursal Duramaz, Melike Ersoy & Esra Sevketoglu. (2016) Acute severe organophosphate poisoning in a child who was successfully treated with therapeutic plasma exchange, high-volume hemodiafiltration, and lipid infusion. Journal of Clinical Apheresis 31:5, pages 467-469.
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Jens von der Wellen, Anne Bierwisch, Franz Worek, Horst Thiermann & Timo Wille. (2016) Kinetics of pesticide degradation by human fresh frozen plasma (FFP) in vitro. Toxicology Letters 244, pages 124-128.
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Elspeth J. Hulse, James O. J. Davies, A. John Simpson, Alfred M. Sciuto & Michael Eddleston. (2014) Respiratory Complications of Organophosphorus Nerve Agent and Insecticide Poisoning. Implications for Respiratory and Critical Care. American Journal of Respiratory and Critical Care Medicine 190:12, pages 1342-1354.
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Hadi Mirfazaeli, Shekoufeh Nikfar, Mohammad-Amin Rezvanfar & Mohammad Abdollahi. (2014) Efficacy of Plasma Transfusion in Acute Human Organophosphorus Poisoning: A Systematic Review and Meta-analysis. International Journal of Pharmacology 10:6, pages 299-306.
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Timo Wille, Horst Thiermann & Franz Worek. (2013) In vitro kinetics of nerve agent degradation by fresh frozen plasma (FFP). Archives of Toxicology 88:2, pages 301-307.
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Mohammad Moshiri, Anahita Alizadeh & Mahdi Balali-Mood. 2014. Basic and Clinical Toxicology of Organophosphorus Compounds. Basic and Clinical Toxicology of Organophosphorus Compounds 177 212 .
Darren M. Roberts & Jonathan Brett. 2014. Basic and Clinical Toxicology of Organophosphorus Compounds. Basic and Clinical Toxicology of Organophosphorus Compounds 141 175 .
Mustafa Yilmaz, Ahmet Sebe, Mehmet Oguzhan Ay, Umut Gumusay, Metin Topal, Mesude Atli, Ferhat Icme & Salim Satar. (2013) Effectiveness of therapeutic plasma exchange in patients with intermediate syndrome due to organophosphate intoxication. The American Journal of Emergency Medicine 31:6, pages 953-957.
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Oksana Lockridge. 2013. 179 205 .
Mohammd Moshiri, Emadodin Darchini-Maragheh & Mahdi Balali-Mood. (2012) Advances in toxicology and medical treatment of chemical warfare nerve agents. DARU Journal of Pharmaceutical Sciences 20:1.
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Lucy Yang, Simon Stanworth, Sally Hopewell, Carolyn Doree & Mike Murphy. (2012) Is fresh-frozen plasma clinically effective? An update of a systematic review of randomized controlled trials (CME). Transfusion 52:8, pages 1673-1686.
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