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Research article

Post-exposure therapy with human butyrylcholinesterase following percutaneous VX challenge in guinea pigs

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Pages 287-297 | Received 23 Jan 2011, Accepted 02 Mar 2011, Published online: 12 May 2011

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Patrick Masson. (2016) Novel approaches in prophylaxis/pretreatment and treatment of organophosphorus poisoning. Phosphorus, Sulfur, and Silicon and the Related Elements 191:11-12, pages 1433-1443.
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Laetitia Poirier, Pauline Jacquet, Laure Plener, Patrick Masson, David Daudé & Eric Chabrière. (2018) Organophosphorus poisoning in animals and enzymatic antidotes. Environmental Science and Pollution Research 28:20, pages 25081-25106.
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Libin Zhang, Hironobu Murata, Gabriel Amitai, Paige N. Smith, Krzysztof Matyjaszewski & Alan J. Russell. (2020) Catalytic Detoxification of Organophosphorus Nerve Agents by Butyrylcholinesterase-Polymer-Oxime Bioscavengers. Biomacromolecules 21:9, pages 3867-3877.
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Lumei Liu, Youngmi Koo, Teal Russell, Elaine Gay, Yan Li & Yeoheung Yun. (2020) Three-dimensional brain-on-chip model using human iPSC-derived GABAergic neurons and astrocytes: Butyrylcholinesterase post-treatment for acute malathion exposure. PLOS ONE 15:3, pages e0230335.
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Kevin G McGarry, Remy F Lalisse, Robert A Moyer, Kristyn M Johnson, Alexi M Tallan, Tyson P Winters, Joeseph E Taris, Craig A McElroy, Erin E Lemmon, Hannah S Shafaat, Yamin Fan, Aniliese Deal, Sean C Marguet, Jill A Harvilchuck, Christopher M Hadad & David W Wood. (2020) A Novel, Modified Human Butyrylcholinesterase Catalytically Degrades the Chemical Warfare Nerve Agent, Sarin. Toxicological Sciences 174:1, pages 133-146.
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Libin Zhang, Stefanie L. Baker, Hironobu Murata, Nicholas Harris, Weihang Ji, Gabriel Amitai, Krzysztof Matyjaszewski & Alan J. Russell. (2019) Tuning Butyrylcholinesterase Inactivation and Reactivation by Polymer‐Based Protein Engineering. Advanced Science 7:1, pages 1901904.
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P. Jacquet, L. Poirier, D. Daudé & E. Chabrière. (2019) Intoxication aux organophosphorés : vers des traitements enzymatiques. Annales Pharmaceutiques Françaises 77:5, pages 349-362.
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Lorena R. Braid, Catherine A. Wood & Barry N. Ford. (2019) Human umbilical cord perivascular cells: A novel source of the organophosphate antidote butyrylcholinesterase. Chemico-Biological Interactions 305, pages 66-78.
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Patrick Masson & Florian Nachon. (2017) Cholinesterase reactivators and bioscavengers for pre- and post-exposure treatments of organophosphorus poisoning. Journal of Neurochemistry 142, pages 26-40.
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Beth A. Reed, Carol L. Sabourin & David E. Lenz. (2017) Human butyrylcholinesterase efficacy against nerve agent exposure. Journal of Biochemical and Molecular Toxicology 31:5, pages e21886.
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Timo Wille, Jens von der Wellen, Horst Thiermann & Franz Worek. (2016) Pseudocatalytic scavenging of the nerve agent VX with human blood components and the oximes obidoxime and HI-6. Archives of Toxicology 91:3, pages 1309-1318.
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Jeffrey L. Langston & Todd M. Myers. (2016) VX toxicity in the Göttingen minipig. Toxicology Letters 264, pages 12-19.
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Helen Rice, Tom M. Mann, Stuart J. Armstrong, Matthew E. Price, A. Chris Green & John E.H. Tattersall. (2016) The potential role of bioscavenger in the medical management of nerve-agent poisoned casualties. Chemico-Biological Interactions 259, pages 175-181.
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Melanie G. Kirkpatrick, Robert C. diTargiani, Richard E. Sweeney & Tamara C. Otto. (2016) Use of V agents and V-analogue compounds to probe the active site of atypical butyrylcholinesterase from Oryzias latipes. Chemico-Biological Interactions 259, pages 182-186.
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Franz Worek, Timo Wille, Marianne Koller & Horst Thiermann. (2016) Toxicology of organophosphorus compounds in view of an increasing terrorist threat. Archives of Toxicology 90:9, pages 2131-2145.
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Allister Vale, Timothy C. Marrs & Paul Rice. (2016) Chemical terrorism and nerve agents. Medicine 44:2, pages 106-108.
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A.-C. Cuquel, F. Dorandeu, F. Ceppa, C. Renard & P. Burnat. (2015) Le VR, version russe du neurotoxique organophosphoré VX. Annales Pharmaceutiques Françaises 73:3, pages 180-189.
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Franz Worek, Gabriele Horn, Timo Wille & Horst Thiermann. (2015) Adaptation of a dynamic in vitro model with real-time determination of butyrylcholinesterase activity in the presence of cyclosarin and an oxime. Toxicology in Vitro 29:1, pages 162-167.
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David A. Jett & David T. Yeung. 2015. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 1049 1056 .
Christopher M. Timperley & John Tattersall. 2015. Best Synthetic Methods. Best Synthetic Methods 1 89 .
Franz Worek, Thomas Seeger, Georg Reiter, Moshe Goldsmith, Yacov Ashani, Haim Leader, Joel L. Sussman, Nidhi Aggarwal, Horst Thiermann & Dan S. Tawfik. (2014) Post-exposure treatment of VX poisoned guinea pigs with the engineered phosphotriesterase mutant C23: A proof-of-concept study. Toxicology Letters 231:1, pages 45-54.
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Franz Worek, Thomas Seeger, Michael Zengerle, Stefan Kubik, Horst Thiermann & Timo Wille. (2014) Effectiveness of a substituted β-cyclodextrin to prevent cyclosarin toxicity in vivo. Toxicology Letters 226:2, pages 222-227.
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Rakesh K. Sit, Valery V. Fokin, Gabriel Amitai, K. Barry Sharpless, Palmer Taylor & Zoran Radić. (2014) Imidazole Aldoximes Effective in Assisting Butyrylcholinesterase Catalysis of Organophosphate Detoxification. Journal of Medicinal Chemistry 57:4, pages 1378-1389.
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Timo Wille, Horst Thiermann & Franz Worek. (2013) In vitro kinetics of nerve agent degradation by fresh frozen plasma (FFP). Archives of Toxicology 88:2, pages 301-307.
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James C. Ball. (2013) BINDING OF QUATERNARY AMMONIUM SALTS TO ACETYLCHOLINE RECEPTORS: POSSIBLE CHEMICAL WARFARE NERVE AGENTS. Military Medical Science Letters 82:1, pages 2-24.
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Helen Mumford, Cerys J. Docx, Matthew E. Price, A. Christopher Green, John E.H. Tattersall & Stuart J. Armstrong. (2013) Human plasma-derived BuChE as a stoichiometric bioscavenger for treatment of nerve agent poisoning. Chemico-Biological Interactions 203:1, pages 160-166.
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Zoran RadićTrevor DaleZrinka Kovarik, Suzana Berend, Edzna GarciaLimin ZhangGabriel Amitai, Carol GreenBožica Radić, Brendan M. DugganDariush AjamiJulius RebekJrJrPalmer Taylor. (2013) Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes. Biochemical Journal 450:1, pages 231-242.
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Allister Vale, Timothy C. Marrs & Paul Rice. (2012) Chemical terrorism and nerve agents. Medicine 40:2, pages 77-79.
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Helen Mumford & John K. Troyer. (2011) Post-exposure therapy with recombinant human BuChE following percutaneous VX challenge in guinea-pigs. Toxicology Letters 206:1, pages 29-34.
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