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Clinical Toxicology Volume 49, 2011 - Issue 9
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Research Article

Clinical and analytical features of severe suicidal quetiapine overdoses – a retrospective cohort study

Florian EyerToxicological Department, Klinikum rechts der Isar, Ismaninger Strasse 22, Munich, GermanyCorrespondence[email protected]
,
Rudolf PfabToxicological Department, Klinikum rechts der Isar, Ismaninger Strasse 22, Munich, Germany
,
Norbert FelgenhauerToxicological Department, Klinikum rechts der Isar, Ismaninger Strasse 22, Munich, Germany
,
Tim StrubelDepartment of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Ismaninger Strasse 22, Munich, Germany
,
Bernd SaugelMedical Intensive Care Unit, Klinikum rechts der Isar, II. Medizinische Klinik, Ismaninger Strasse 22, Munich, Germany
&
Thomas ZilkerToxicological Department, Klinikum rechts der Isar, Ismaninger Strasse 22, Munich, Germany
Pages 846-853 | Received 05 Aug 2011, Accepted 13 Sep 2011, Published online: 14 Nov 2011

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Fumiya Inoue, Kenichiro Iga, Keisuke Maeda, Satoshi Sera, Noritomo Fujisaki, Yuji Okazaki, Toshihisa Ichiba, Takuyo Chiba & Akira Namera. (2023) Refractory seizures due to severe quetiapine poisoning. Clinical Toxicology 61:8, pages 620-621.
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Jianbo Lai, Qiaoqiao Lu, Tingting Huang, Shaohua Hu & Yi Xu. (2017) Convulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder. Neuropsychiatric Disease and Treatment 13, pages 1905-1908.
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Christine Rauber-Lüthy, Katharina E. Hofer, Michael Bodmer, Gerd A. Kullak-Ublick, Hugo Kupferschmidt & Alessandro Ceschi. (2013) Gastric pharmacobezoars in quetiapine extended-release overdose: A case series. Clinical Toxicology 51:10, pages 937-940.
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Malin Bartos & Kai Knudsen. (2013) Use of intravenous lipid emulsion in the resuscitation of a patient with cardiovascular collapse after a severe overdose of quetiapine. Clinical Toxicology 51:6, pages 501-504.
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Mohammad Sayyah, Sayeh Majzoob & Mehdi Sayyah. (2013) Metabolic and toxicological considerations for obsessive–compulsive disorder drug therapy. Expert Opinion on Drug Metabolism & Toxicology 9:6, pages 657-673.
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Lukas Lannemyr & Kai Knudsen. (2012) Severe overdose of quetiapine treated successfully with extracorporeal life support. Clinical Toxicology 50:4, pages 258-261.
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Articles from other publishers (28)

Luyao He, Yimin Yu, Lei Zhang, Shen He, Wenjuan Yu, Lujin Li, Jingjing Huang & Huafang Li. (2022) A Real-World Study of Risk Factors for QTc Prolongation in Schizophrenia Patients Receiving Atypical Antipsychotics. Journal of Clinical Psychopharmacology 42:1, pages 71-74.
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Filippo MILANO, Stefania URSO & Enrico DE DOMINICIS. (2021) Toxicological and histopathological findings in a suicidal quetiapine overdose. Minerva Medicolegale 140:4.
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Müge TOPCUOĞLU & Ali ERDOĞAN. (2020) Interstitial Lung Disease due to Quetiapine: Case Report and Literature ReviewKetiapine Bağlı İnterstisyel Akciğer Hastalığı: Olgu Sunumu ve Literatür İncelemesi. Düzce Tıp Fakültesi Dergisi 22:2, pages 140-142.
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Julia Tschirdewahn & Florian Eyer. (2019) Diagnostik und Behandlung ausgesuchter akuter Arzneimittelvergiftungen mit hoher klinischer RelevanzDiagnostics and treatment of selected clinically relevant, acute drug intoxications. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 62:11, pages 1313-1323.
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Lorenzo Giuntoli, Vittorio Dalmastri, Nicola Cilloni, Claudio Orsi, Lucia Stalteri, Valentina Demelas, Giovanni Giuliani, Giovanni Gordini, Fabrizio De Ponti & Gaetano La Manna. (2019) Severe quetiapine voluntary overdose successfully treated with a new hemoperfusion sorbent. The International Journal of Artificial Organs 42:9, pages 516-520.
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Jozef Klučka, Tomáš Juřenčák, Martina Kosinová, Štourač Petr, Milan Kratochvíl, Yvona Sedláčková, Navrátil Tomáš, Daniela Pelclová & Petr Jabandžiev. (2019) Intralipid infusion in paediatric patient with quetiapine and lamotrigine intoxication. Monatshefte für Chemie - Chemical Monthly 150:9, pages 1711-1714.
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Lucy Taylor & Andis Graudins. (2018) Extended‐release quetiapine overdose is associated with delayed onset of toxicity compared to immediate‐release quetiapine overdose. Emergency Medicine Australasia 31:4, pages 562-568.
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Elise Peridy, Jean-François Hamel, Anne-Lise Rolland, Bénédicte Gohier & David Boels. (2019) Quetiapine Poisoning and Factors Influencing Severity. Journal of Clinical Psychopharmacology 39:4, pages 312-317.
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Ann M. Arens & Tom Kearney. (2019) Adverse Effects of Physostigmine. Journal of Medical Toxicology 15:3, pages 184-191.
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S. Lienert, H. Braun-Scharm, S. Schäfer, C. Fusch, J. Kunkel & P. Nonell. (2017) Suizid bei dualer Pharmakotherapie in der AdoleszenzSuicide in an adolescent receiving dual pharmacotherapy. Monatsschrift Kinderheilkunde 166:7, pages 600-604.
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Betty S. Chan, Therese Becker, Angela L. Chiew, Ahmed M. Abdalla, Tom A. Robertson, Xin Liu, Michael S. Roberts & Nicholas A. Buckley. (2017) Vasoplegic Shock Treated with Methylene Blue Complicated by Severe Serotonin Syndrome. Journal of Medical Toxicology 14:1, pages 100-103.
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David F. Lehmann, William D. Eggleston & Dongliang Wang. (2018) Validation and Clinical Utility of the hERG IC 50:C max Ratio to Determine the Risk of Drug‐Induced Torsades de Pointes: A Meta‐Analysis . Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 38:3, pages 341-348.
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Jason A. Chen, Katherine M. Unverferth & Erick H. Cheung. (2018) Delayed-Onset Seizure in a Mild Quetiapine Overdose: Report of a Case and Review of the Literature. Case Reports in Psychiatry 2018, pages 1-3.
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Yuriy P. Orlov. (2017) Modern First Aid Tactics and New Techniques in Acute Poisoning Intensive Therapy. Annals of Critical Care:3, pages 58-62.
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José R. Maldonado. (2017) Acute Brain Failure. Critical Care Clinics 33:3, pages 461-519.
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Evan S. Schwarz, Kathryn T. Kopec, Timothy J. Wiegand, Paul M. Wax & Jeffrey Brent. (2017) Should We Be Using the Poisoning Severity Score?. Journal of Medical Toxicology 13:2, pages 135-145.
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Jerrold B. Leikin & Andrea Carlson. 2017. Critical Care Toxicology. Critical Care Toxicology 425 446 .
Tilman Steinert & Walter Fröscher. 2016. Life-Threatening Effects of Antipsychotic Drugs. Life-Threatening Effects of Antipsychotic Drugs 207 222 .
Jerrold B. Leikin & Andrea Carlson. 2016. Critical Care Toxicology. Critical Care Toxicology 1 22 .
Michael Paulzen, Gerhard Gründer, Thorsten Orlikowsky, Charlotte M. Gräf, Maria Hoeltzenbein & Tanja Veselinovic. (2015) Suicide Attempt During Late Pregnancy With Quetiapine. Journal of Clinical Psychopharmacology 35:3, pages 343-344.
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Margaret E. MattsonVictoria A. AlbrightJoanna YoonCarol L. Council. (2015) Emergency Department Visits Involving Misuse and Abuse of the Antipsychotic Quetiapine: Results from the Drug Abuse Warning Network (DAWN). Substance Abuse: Research and Treatment 9, pages SART.S22233.
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José R. Maldonado. 2015. Handbook of Consultation-Liaison Psychiatry. Handbook of Consultation-Liaison Psychiatry 157 187 .
Mehrul Hasnain & W. Victor R. Vieweg. (2014) QTc Interval Prolongation and Torsade de Pointes Associated with Second-Generation Antipsychotics and Antidepressants: A Comprehensive Review. CNS Drugs 28:10, pages 887-920.
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Marianne Meli, Christine Rauber-Lüthy, Petra Hoffmann-Walbeck, Hans-Jürgen Reinecke, Dagmar Prasa, Uwe Stedtler, Elke Färber, Dieter Genser, Hugo Kupferschmidt, Gerd A. Kullak-Ublick & Alessandro Ceschi. (2013) Atypical antipsychotic poisoning in young children: a multicentre analysis of poisons centres data. European Journal of Pediatrics 173:6, pages 743-750.
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Dieter Müller & Herbert Desel. (2013) Common Causes of Poisoning. Deutsches Ärzteblatt international.
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Georgios Papazisis, Orthodoxia Mastrogianni, Fotios Chatzinikolaou, Nikolaos Vasiliadis & Nikolaos Raikos. (2012) Sudden cardiac death due to quetiapine overdose. Psychiatry and Clinical Neurosciences 66:6, pages 535-535.
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Matthew W. Hedge. (2012) Miscellaneous Central Nervous System Intoxicants. Critical Care Clinics 28:4, pages 587-600.
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Antonios Liolios & Othman Sentissi. (2012) Rhabdomyolysis following Acute Extended-Release Quetiapine Poisoning: A Case Report. Case Reports in Psychiatry 2012, pages 1-2.
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