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Clinical Toxicology Volume 50, 2012 - Issue 1
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Research Articles

The role of the glutathione S-transferase genes GSTT1, GSTM1, and GSTP1 in acetaminophen-poisoned patients

Anders BuchardDepartment of Forensic Medicine, University of Copenhagen, Copenhagen, DenmarkCorrespondence[email protected]
,
Martin EefsenDepartment of Hepatology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
,
Synne SembDepartment of Gastroenterology, Hvidovre University Hospital, Copenhagen, Denmark
,
Stig Ejdrup AndersenDepartment of Clinical Pharmacology, Bispebjerg University Hospital, Copenhagen, Denmark
,
Niels MorlingDepartment of Gastroenterology, Hvidovre University Hospital, Copenhagen, Denmark
,
Flemming BendtsenDepartment of Gastroenterology, Hvidovre University Hospital, Copenhagen, Denmark
,
Fin Stolze LarsenDepartment of Hepatology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
&
Kim DalhoffDepartment of Clinical Pharmacology, Bispebjerg University Hospital, Copenhagen, Denmark
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Pages 27-33 | Received 07 Jul 2011, Accepted 07 Nov 2011, Published online: 19 Dec 2011

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Hamdy Awad, Ahmed Ahmed, Richard D Urman, Nicoleta Stoicea & Sergio D Bergese. (2019) Potential role of pharmacogenomics testing in the setting of enhanced recovery pathways after surgery. Pharmacogenomics and Personalized Medicine 12, pages 145-154.
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Maiyen Tran Hawkins & James H Lewis. (2012) Latest advances in predicting DILI in human subjects: focus on biomarkers. Expert Opinion on Drug Metabolism & Toxicology 8:12, pages 1521-1530.
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Articles from other publishers (10)

Michael H. Court. 2017. Biomarkers in Liver Disease. Biomarkers in Liver Disease 639 665 .
Michael H. Court. 2016. Biomarkers in Liver Disease. Biomarkers in Liver Disease 1 27 .
Toshikazu Yamaoka & Yoshiaki Kitamura. (2015) Characterization of a highly sensitive and selective novel trapping reagent, stable isotope labeled glutathione ethyl ester, for the detection of reactive metabolites. Journal of Pharmacological and Toxicological Methods 76, pages 83-95.
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Liudmila L. Mazaleuskaya, Katrin Sangkuhl, Caroline F. Thorn, Garret A. FitzGerald, Russ B. Altman & Teri E. Klein. (2015) PharmGKB summary. Pharmacogenetics and Genomics 25:8, pages 416-426.
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Marlon J.A. Jetten, Sandra M. Claessen, Cornelis H.C. Dejong, Agustin Lahoz, José V. Castell, Joost H.M. van Delft & Jos C.S. Kleinjans. (2014) Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices. Toxicology 323, pages 61-69.
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Si-Hyang Park, Sung-Sil Moon, Cheng-Liang Xie, Se-Young Choung & Yeung-Joon Choi. (2014) Protective Effects of Enzymatic Oyster Hydrolysate on Acetaminophen-induced HepG-2 Cell Damage. Journal of the Korean Society of Food Science and Nutrition 43:8, pages 1166-1173.
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Sanja Dragovic, Harini Venkataraman, Selina Begheijn, Nico P.E. Vermeulen & Jan N.M. Commandeur. (2014) Effect of human glutathione S-transferase hGSTP1-1 polymorphism on the detoxification of reactive metabolites of clozapine, diclofenac and acetaminophen. Toxicology Letters 224:2, pages 272-281.
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Mitchell R. McGill & Hartmut Jaeschke. (2013) Metabolism and Disposition of Acetaminophen: Recent Advances in Relation to Hepatotoxicity and Diagnosis. Pharmaceutical Research 30:9, pages 2174-2187.
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Michael H. Court, Marina Freytsis, Xueding Wang, Inga Peter, Chantal Guillemette, Suwagmani Hazarika, Su X. Duan, David J. Greenblatt & William M. Lee. (2013) The UDP-Glucuronosyltransferase (UGT) 1A Polymorphism c.2042C>G (rs8330) Is Associated with Increased Human Liver Acetaminophen Glucuronidation, Increased UGT1A Exon 5a/5b Splice Variant mRNA Ratio, and Decreased Risk of Unintentional Acetaminophen-Induced Acute Liver Failure. Journal of Pharmacology and Experimental Therapeutics 345:2, pages 297-307.
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Khyber Saify, Iraj Saadat & Mostafa Saadat. (2012) Genetic polymorphisms of glutathione S-transferase T1 (GSTT1) and M1 (GSTM1) in selected populations of Afghanistan. Molecular Biology Reports 39:8, pages 7855-7859.
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