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Clinical Toxicology Volume 51, 2013 - Issue 7
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Research Article

A case series of patients with lamotrigine toxicity at one center from 2003 to 2012

P. W. MoorePinnacleHealth Toxicology Center, Department of Internal Medicine, Harrisburg, PA, USA;Penn State University College of Medicine, Department of Emergency Medicine, Hershey, PA, USACorrespondence[email protected]
,
J. W. DonovanPinnacleHealth Toxicology Center, Department of Internal Medicine, Harrisburg, PA, USA;Penn State University College of Medicine, Department of Emergency Medicine, Hershey, PA, USA
,
K. K. BurkhartPinnacleHealth Toxicology Center, Department of Internal Medicine, Harrisburg, PA, USA;Food and Drug Administration, Silver Spring, MD, USA;Penn State University College of Medicine, Department of Emergency Medicine, Hershey, PA, USA
&
D. HaggertyPinnacleHealth Toxicology Center, Department of Internal Medicine, Harrisburg, PA, USA
Pages 545-549 | Received 07 Feb 2013, Accepted 18 Jun 2013, Published online: 19 Jul 2013

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Kengo Hatanaka, Yoshito Kamijo, Takeshi Kitamoto, Tomoki Hanazawa, Tomohiro Yoshizawa, Hidenobu Ochiai & Yoshiyuki Haga. (2022) Effectiveness of multiple-dose activated charcoal in lamotrigine poisoning: a case series. Clinical Toxicology 60:3, pages 379-381.
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Rebecca E. Bruccoleri, Bradley L. Demeter, Peter R. Chai & Michele M. Burns. (2019) Massive lamotrigine and bupropion overdose resulting in status epilepticus without cardiovascular collapse. Toxicology Communications 3:1, pages 102-105.
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Bader Alyahya, Marjorie Friesen, Bénédicte Nauche & Martin Laliberté. (2018) Acute lamotrigine overdose: a systematic review of published adult and pediatric cases. Clinical Toxicology 56:2, pages 81-89.
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Juan Antonio Contreras Vite, Carlos Vega Valle, Happi Biekeu Mbem, Sarah-Maude Boivin & Robert Dumaine. (2022) Epilepsy-Induced High Affinity Blockade of the Cardiac Sodium Current INa by Lamotrigine; A Potential for Acquired Arrythmias. Pharmaceuticals 15:10, pages 1208.
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Judith A. Restrepo, Rachel L. MacLean, Christopher M. Celano, Jeffery C. Huffman, James L. Januzzi & Scott R. Beach. (2022) The assessment of cardiac risk in patients taking lamotrigine; a systematic review. General Hospital Psychiatry 78, pages 14-27.
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Alexander D. Blanchette, Sarah D. Burnett, Ivan Rusyn & Weihsueh A. Chiu. (2022) A tiered approach to population-based in vitro testing for cardiotoxicity: Balancing estimates of potency and variability. Journal of Pharmacological and Toxicological Methods 114, pages 107154.
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Kelly E. Wood, Kendra L. Palmer & Matthew D. Krasowski. (2021) Data on the relationship between lamotrigine and levetiracetam serum/plasma levels and toxicity: Experience at an academic medical center. Data in Brief 39, pages 107555.
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Alexis S. McLaine, Page E. Yaxley, Anda A. Young & Edward S. Cooper. (2021) Successful management of massive lamotrigine extended‐release intoxication in a dog. Clinical Case Reports 9:12.
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Kelly E. Wood, Kendra L. Palmer & Matthew D. Krasowski. (2021) Correlation of elevated lamotrigine and levetiracetam serum/plasma levels with toxicity: A long-term retrospective review at an academic medical center. Toxicology Reports 8, pages 1592-1598.
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Aurélie Muckensturm, Marjorie Cheze, Daniel Valet, Marie-Charlotte Quinton, Sandra Bodeau, Anne-Sophie Lemaire-Hurtel, Marc Deveaux & Guillaume Hoizey. (2020) Trouble factice imposé à autrui : à propos d’un cas d’intoxication par la lamotrigine, documenté par l’analyse des cheveux. Toxicologie Analytique et Clinique 32:3, pages 210-216.
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Simon P. HagleySteven E. EpsteinJoshua A. SternRobert Poppenga. (2020) Lamotrigine Toxicosis Treated with Intravenous Lipid Emulsion Therapy in a Dog. Journal of the American Animal Hospital Association 56:4, pages 226-230.
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Abhinav Agrawal, Joshua N. Nogar & Seth Koenig. (2019) Management of lamotrigine overdose using hemodialysis. The American Journal of Emergency Medicine 37:8, pages 1603.e1-1603.e2.
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Alexander D. Blanchette, Fabian A. Grimm, Chimedullam Dalaijamts, Nan‐Hung Hsieh, Kyle Ferguson, Yu‐Syuan Luo, Ivan Rusyn & Weihsueh A. Chiu. (2018) Thorough QT/QTc in a Dish: An In Vitro Human Model That Accurately Predicts Clinical Concentration‐QTc Relationships . Clinical Pharmacology & Therapeutics 105:5, pages 1175-1186.
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Ashley Griswold, Briana Tully, Kenneth Katz, Gillian Beauchamp, Matthew Cook & Robert Cannon. (2019) Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion. Case Reports in Emergency Medicine 2019, pages 1-3.
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Mario Tombini, Giovanni Pellegrino, Giovanni Assenza & Vincenzo Di Lazzaro. (2017) De novo multifocal myoclonus induced by lamotrigine in a temporal lobe epilepsy case. Journal of the Neurological Sciences 373, pages 31-32.
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Shishir Rao, Meghan Harper-Shankie & Rajkumar Agarwal. (2017) Vertical gaze palsy due to medication error. Epilepsy & Behavior Case Reports 8, pages 33-34.
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Sokratis E. Karaoulanis, Markos Syngelakis & Konstantinos Fokas. (2016) Rhabdomyolysis after lamotrigine overdose: a case report and review of the literature. Annals of General Psychiatry 15:1.
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Akintunde Alabi, Adam Todd, Andrew Husband & Joe Reilly. (2016) Safety profile of lamotrigine in overdose. Therapeutic Advances in Psychopharmacology 6:6, pages 369-381.
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M. P. Emswiler & K. L. Cumpston. 2016. Critical Care Toxicology. Critical Care Toxicology 1 18 .
Sara K. Lookabill, Anna Rouse Dulaney, Greene Shepherd & William P. KernsIIII. 2016. Critical Care Toxicology. Critical Care Toxicology 1 21 .
Patricia Chavez, Abel Casso Dominguez & Eyal Herzog. (2014) Evolving Electrocardiographic Changes in Lamotrigine Overdose: A Case Report and Literature Review. Cardiovascular Toxicology 15:4, pages 394-398.
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Girish S. Naik, Rohit Kodagali, Binu S. Mathew, Maya Thomas, Ratna Prabha, Vivek Mathew & Denise H. Fleming. (2015) Therapeutic Drug Monitoring of Levetiracetam and Lamotrigine. Therapeutic Drug Monitoring 37:4, pages 437-444.
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P.D. Thompson, T.J. Kleinig & T.E. Kimber. 2015. Medication-Induced Movement Disorders. Medication-Induced Movement Disorders 160 167 .
Alica M. Goldman. (2015) Mechanisms of sudden unexplained death in epilepsy. Current Opinion in Neurology 28:2, pages 166-174.
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