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Clinical Toxicology Volume 52, 2014 - Issue 1
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Research Article

Adverse effects associated with high-dose olanzapine therapy in patients admitted to inpatient psychiatric care

A. B. PetersenDepartment of Clinical Pharmacology, Bispebjerg Hospital, Copenhagen, DenmarkCorrespondence[email protected]
,
S. E. AndersenDepartment of Clinical Pharmacology, Bispebjerg Hospital, Copenhagen, Denmark
,
M. ChristensenDepartment of Clinical Pharmacology, Bispebjerg Hospital, Copenhagen, Denmark
&
H. L. LarsenDepartment of Clinical Pharmacology, Bispebjerg Hospital, Copenhagen, Denmark
Pages 39-43 | Received 13 Jun 2013, Accepted 31 Oct 2013, Published online: 09 Dec 2013

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Yasar Torres-Yaghi, Amelia Carwin, Jacob Carolan, Steven Nakano, Fahd Amjad & Fernando Pagan. (2021) QTc Interval Prolongation with Therapies Used to Treat Patients with Parkinson’s Disease Psychosis: A Narrative Review. Neuropsychiatric Disease and Treatment 17, pages 3791-3818.
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Sharan L. Campleman, Jeffery Brent, Anthony F. Pizon, Joshua Shulman, Paul Wax & Alex F. Manini. (2020) Drug-specific risk of severe QT prolongation following acute drug overdose. Clinical Toxicology 58:12, pages 1326-1334.
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Stine Toft, Henrik Horwitz & Kim Peder Dalhoff. (2017) Long-term mortality after poisoning with antipsychotics. Clinical Toxicology 55:4, pages 267-274.
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Articles from other publishers (18)

ZhenYu Zhu, Ting Cao, Hui Chen, BiKui Zhang, ChenQuan Lin & HuaLin Cai. (2023) Olanzapine-induced nonalcoholic fatty liver disease: The effects of differential food pattern and the involvement of PGRMC1 signaling. Food and Chemical Toxicology 176, pages 113757.
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Louisa Gannon, John Reynolds, Martin Mahon, Fiona Gaughran & John Lally. (2023) High-dose olanzapine in treatment-resistant schizophrenia: a systematic review. Therapeutic Advances in Psychopharmacology 13, pages 204512532311687.
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Margo Funk & Scott Beach. 2022. Torsades de Pointes. Torsades de Pointes 213 229 .
Hisao Naono, Ryuichiro Takeda, Hiroyuki Masuyama, Jiro Kawano, Keiko Naono‐Nagatomo & Yasushi Ishida. (2022) Case of reversible Mobitz type II atrioventricular block after the use of injectable antipsychotics. Clinical Case Reports 10:1.
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Komugi Okeya, Fuminari Misawa, Yasuo Fujii & Hiroyoshi Takeuchi. (2021) Olanzapine Reduction From High Dose to Standard Dose. Journal of Clinical Psychopharmacology 41:6, pages 676-680.
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Zehra Boz, Minmin Hu, Yinghua Yu & Xu-Feng Huang. (2020) N-acetylcysteine prevents olanzapine-induced oxidative stress in mHypoA-59 hypothalamic neurons. Scientific Reports 10:1.
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Joshua PepperLudvic Zrinzo & Marwan Hariz. (2020) Anterior capsulotomy for obsessive-compulsive disorder: a review of old and new literature. Journal of Neurosurgery 133:5, pages 1595-1604.
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Kerstin Schweyer, Bastian Fatke, Kornelia Kreiser, Christian Rabe, Christian Seifert & Benno Ikenberg. (2020) Bilateral Basal Ganglion Hemorrhage after Severe Olanzapine Intoxication. Case Reports in Psychiatry 2020, pages 1-3.
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Lei Sun, Sergey Yagoda, Hongqi Xue, Randy Brown, Narinder Nangia, David McDonnell, Bhaskar Rege, Lisa von Moltke & Borje Darpo. (2020) Combination of olanzapine and samidorphan has no clinically relevant effects on ECG parameters, including the QTc interval: Results from a phase 1 QT/QTc study. Progress in Neuro-Psychopharmacology and Biological Psychiatry 100, pages 109881.
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Joseph Westermeyer. (2019) Call for “High-Dose” Olanzapine Research in Treatment-Resistant Psychosis. Journal of Nervous & Mental Disease 207:1, pages 45-47.
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Rudolph M. Navari. 2019. International Manual of Oncology Practice. International Manual of Oncology Practice 1007 1045 .
Martin Hýža. (2018) Is there an evidence for the efficacy of high-dose olanzapine?. Psychiatrie pro praxi 19:1, pages 22-23.
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Scott R. Beach, Christopher M. Celano, Alan M. Sugrue, Caitlin Adams, Michael J. Ackerman, Peter A. Noseworthy & Jeff C. Huffman. (2018) QT Prolongation, Torsades de Pointes, and Psychotropic Medications: A 5-Year Update. Psychosomatics 59:2, pages 105-122.
Crossref
Yung-Fu Wu. (2017) Recurrent Hyperammonemia Associated With Olanzapine. Journal of Clinical Psychopharmacology 37:3, pages 366-367.
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Bianca Blanch, Nicholas A. Buckley, Leigh Mellish, Andrew H. Dawson, Paul S. Haber & Sallie-Anne Pearson. (2015) Harmonizing Post-Market Surveillance of Prescription Drug Misuse: A Systematic Review of Observational Studies Using Routinely Collected Data (2000–2013). Drug Safety 38:6, pages 553-564.
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Zampas Constantinos, Papadopoulou Eleni, Antonis Goulas & Zafiroula Iakovidou - Kritsi. (2015) Olanzapine: evaluation of the in vivo cytogenetic effect . Human Psychopharmacology: Clinical and Experimental 30:3, pages 189-192.
Crossref
. (2015) Olanzapine/various other drugs. Reactions Weekly 1545:1, pages 186-186.
Crossref
P. Chue & G. Baker. 2015. A worldwide yearly survey of new data in adverse drug reactions. A worldwide yearly survey of new data in adverse drug reactions 63 83 .

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