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Clinical Toxicology Volume 54, 2016 - Issue 4
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Impairment of mitochondrial respiration following ex vivo cyanide exposure in peripheral blood mononuclear cells

David H. JangDepartment of Emergency Medicine, Center for Mitochondrial Bioenergetics in Emergency Medicine and Critical Care (MitoEM), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Correspondence[email protected]
,
Frances S. ShoferDepartment of Emergency Medicine, Center for Mitochondrial Bioenergetics in Emergency Medicine and Critical Care (MitoEM), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA;
,
Scott L. WeissDepartment of Anesthesia and Critical Care, Division of Critical Care Medicine, The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
&
Lance B. BeckerDepartment of Emergency Medicine, Center for Mitochondrial Bioenergetics in Emergency Medicine and Critical Care (MitoEM), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA;
Pages 303-307 | Received 22 Oct 2015, Accepted 02 Jan 2016, Published online: 05 Feb 2016

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Alexander Reisinger, Jasmin Rabensteiner & Gerald Hackl. (2020) Diagnosis of acute intoxications in critically ill patients: focus on biomarkers – part 2: markers for specific intoxications. Biomarkers 25:2, pages 112-125.
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David H. Jang, Matthew Kelly, Kevin Hardy, David S. Lambert, Frances S. Shofer & David M. Eckmann. (2017) A preliminary study in the alterations of mitochondrial respiration in patients with carbon monoxide poisoning measured in blood cells. Clinical Toxicology 55:6, pages 579-584.
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Articles from other publishers (14)

Alexander J. Michels, Judy A. Butler, Sandra L. Uesugi, Ken Lee, Balz B. Frei, Gerd Bobe, Kathy R. Magnusson & Tory M. Hagen. (2023) Multivitamin/Multimineral Supplementation Prevents or Reverses Decline in Vitamin Biomarkers and Cellular Energy Metabolism in Healthy Older Men: A Randomized, Double-Blind, Placebo-Controlled Study. Nutrients 15:12, pages 2691.
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Oladunni Alomaja, Frances S. Shofer, John C. Greenwood, Sarah Piel, Carly Clayman, Clementina Mesaros, Shih-Han Kao, Samuel S. Shin, Johannes K. Ehinger, Todd J. Kilbaugh & David H. Jang. (2023) Alteration in Cerebral Metabolism in a Rodent Model of Acute Sub-lethal Cyanide Poisoning. Journal of Medical Toxicology 19:2, pages 196-204.
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Amaya Lopez-PascualPaul TrayhurnJ. Alfredo MartínezPedro González-Muniesa. (2021) Oxygen in Metabolic Dysfunction and Its Therapeutic Relevance. Antioxidants & Redox Signaling 35:8, pages 642-687.
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Chaiqin Lei, Jianzhao Liao, Quanwei Li, Jian Shi, Hui Zhang, Jianying Guo, Qingyue Han, Lianmei Hu, Ying Li, Jiaqiang Pan & Zhaoxin Tang. (2021) Copper induces mitochondria-mediated apoptosis via AMPK-mTOR pathway in hypothalamus of Pigs. Ecotoxicology and Environmental Safety 220, pages 112395.
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David H. Jang, Sarah Piel, John C. Greenwood, Johannes K. Ehinger & Todd J. Kilbaugh. (2021) Emerging cellular-based therapies in carbon monoxide poisoning. American Journal of Physiology-Cell Physiology 321:2, pages C269-C275.
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Liang Meng, Deqiang Chen, Gaopei Meng, Li Lu & Chenggang Han. (2021) Dysregulation of the Sirt5/IDH2 axis contributes to sunitinib resistance in human renal cancer cells. FEBS Open Bio 11:3, pages 921-931.
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Castanares-Zapatero Diego & Hantson Philippe. 2021. Mitochondrial Dysfunction and Nanotherapeutics. Mitochondrial Dysfunction and Nanotherapeutics 203 220 .
Kalpita Rashmi Karan, Caroline Trumpff, Marlon A. McGill, Jacob E. Thomas, Gabriel Sturm, Vincenzo Lauriola, Richard P. Sloan, Nicolas Rohleder, Brett A. Kaufman, Anna L. Marsland & Martin Picard. (2020) Mitochondrial respiratory capacity modulates LPS-induced inflammatory signatures in human blood. Brain, Behavior, & Immunity - Health 5, pages 100080.
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Hanming Chen, Gaoyang Liu, Na Qiao, Zhenlong Kang, Lianmei Hu, Jianzhao Liao, Fan Yang, Congying Pang, Bingxian Liu, Qiwen Zeng, Yao Li & Ying Li. (2020) Toxic effects of arsenic trioxide on spermatogonia are associated with oxidative stress, mitochondrial dysfunction, autophagy and metabolomic alterations. Ecotoxicology and Environmental Safety 190, pages 110063.
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Shawn Owiredu, Abhay Ranganathan, John C. Greenwood, Sarah Piel, Joanna I. Janowska, David M. Eckmann, Matthew Kelly, Johannes K. Ehinger, Todd J. Kilbaugh & David H. Jang. (2020) In vitro comparison of hydroxocobalamin (B12a) and the mitochondrial directed therapy by a succinate prodrug in a cellular model of cyanide poisoning. Toxicology Reports 7, pages 1263-1271.
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Mauricio A. Retamal, Viviana P. Orellana, Nicolás J. Arévalo, Cristóbal G. Rojas, Rodolfo J. Arjona, Constanza A. Alcaíno, Wendy González, Jonathan G. Canan, Rodrigo Moraga-Amaro, Jimmy Stehberg, Luis Reuss & Guillermo A. Altenberg. (2019) Cx46 hemichannel modulation by nitric oxide: Role of the fourth transmembrane helix cysteine and its possible involvement in cataract formation. Nitric Oxide 86, pages 54-62.
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David H. Jang, Utsha G. Khatri, Anita Mudan, Jennifer S. Love, Shawn Owiredu & David M. Eckmann. (2018) Translational Application of Measuring Mitochondrial Functions in Blood Cells Obtained from Patients with Acute Poisoning. Journal of Medical Toxicology 14:2, pages 144-151.
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Derek M. Culnan, Beretta Craft-Coffman, Genevieve H. Bitz, Karel D. Capek, Yiji Tu, William C. Lineaweaver & Maggie J. Kuhlmann-Capek. (2018) Carbon Monoxide and Cyanide Poisoning in the Burned Pregnant Patient. Annals of Plastic Surgery 80:3, pages S106-S112.
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David H. Jang, John C. Greenwood, Meghan B. Spyres & David M. Eckmann. (2016) Measurement of Mitochondrial Respiration and Motility in Acute Care. Journal of Intensive Care Medicine 32:1, pages 86-94.
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