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Clinical Toxicology Volume 9, 1976 - Issue 5
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Research Article

Application of Pharmacokinetic Principles in the Extrapolation of Animal Data to Humans

James R. Gillette Laboratory of Chemical Pharmacology National Heart and Lung Institute National Institutes of Health, Bethesda, Maryland
Pages 709-722 | Published online: 25 Sep 2008

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Flavio Gaspari & Maurizio Bonati. (1990) Interspecies Metabolism and Pharmacokinetic Scaling of Theophylline Disposition. Drug Metabolism Reviews 22:2-3, pages 179-207.
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M. Bonati, R. Latini, G. Tognoni, J. F. Young & S. Garattini. (1984) Interspecies Comparison of In Vivo Caffeine Pharmacokinetics in Man, Monkey, Rabbit, Rat and Mouse. Drug Metabolism Reviews 15:7, pages 1355-1383.
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C.Jelleff Carr & Albert C. KolbyeJr.Jr.. (1991) A critique of the use of the maximum tolerated dose in bioassays to assess cancer risks from chemicals. Regulatory Toxicology and Pharmacology 14:1, pages 78-87.
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James T. Stevens & Darrell D. Sumner. 1992. New Trends in Pharmacokinetics. New Trends in Pharmacokinetics 315 333 .
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Ajit K. Thakur. 1988. Pharmacokinetics. Pharmacokinetics 227 244 .
Charles C. Brown. 1987. Toxic Substances and Human Risk. Toxic Substances and Human Risk 237 268 .
Joyce Mordenti. (1986) Dosage Regimen Design for Pharmaceutical Studies Conducted in Animals. Journal of Pharmaceutical Sciences 75:9, pages 852-857.
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William E. Pepelko & James R. Withey. (2016) Methods for Route-To-Route Extrapolation of Dose. Toxicology and Industrial Health 1:4, pages 153-175.
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Richard C. Hertzberg & Michael Miller. (2016) A Statistical Model for Species Extrapolation Using Categorical Response Data. Toxicology and Industrial Health 1:4, pages 43-63.
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Charles C. Brown & James A. Koziol. (1983) Statistical Aspects of the Estimation of Human Risk from Suspected Environmental Carcinogens. SIAM Review 25:2, pages 151-181.
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Harold Boxenbaum. (1982) Comparative pharmacokinetics of benzodiazepines in dog and man. Journal of Pharmacokinetics and Biopharmaceutics 10:4, pages 411-426.
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Robert L. Dedrick. (1981) Dose-Response Analyses of Bone Cancers from Radium. Science 214:4517, pages 207-207.
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Michael J. McKenna. (1979) Letters to the Editor. Environmental Health Perspectives 28, pages 313-313.
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R L Dedrick. (1979) Pharmacokinetics of vinylidene chloride.. Environmental Health Perspectives 28, pages 311-314.
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. (1978) Chapter 7 Metabolism and pharmacokinetics. Food and Cosmetics Toxicology 16, pages 65-81.
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Hugh M. McIlhenny. 1977. 201 209 .

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