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Clinical Toxicology Volume 10, 1977 - Issue 4
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Research Article

Reversal by Physostigmine of Clozapine-Induced Delirium

P. SCHUSTER Psychiatrische Universitätsklinik University of Vienna Lazarettgasse, 14 A-1090, Vienna, Austria
,
E. GABRIEL Psychiatrische Universitätsklinik University of Vienna Lazarettgasse, 14 A-1090, Vienna, Austria
,
B. KÜFFERLE Psychiatrische Universitätsklinik University of Vienna Lazarettgasse, 14 A-1090, Vienna, Austria
,
G. STROBL Psychiatrische Universitätsklinik University of Vienna Lazarettgasse, 14 A-1090, Vienna, Austria
&
M. KAROBATH Psychiatrische Universitätsklinik University of Vienna Lazarettgasse, 14 A-1090, Vienna, Austria
Pages 437-441 | Published online: 25 Sep 2008

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Paolo N. Grenga, Rachel F. Schult & Timothy J. Wiegand. (2018) Physostigmine use in clozapine intoxication from adulterated heroin: an atypical toxidrome with an effective antidote. Toxicology Communications 2:1, pages 53-55.
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Daniel J. Cobaugh, Andrew R. Erdman, Lisa L. Booze, Elizabeth J. Scharman, Gwenn Christianson, Anthony S. Manoguerra, E. Martin Caravati, Peter A. Chyka, Alan D. Woolf, Lewis S. Nelson & William G. Troutman. (2007) Atypical antipsychotic medication poisoning: An evidence-based consensus guideline for out-of-hospital management. Clinical Toxicology 45:8, pages 918-942.
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Joanna Fitzsimons, Michael Berk, Timothy Lambert, Michel Bourin & Seetal Dodd. (2005) A review of clozapine safety. Expert Opinion on Drug Safety 4:4, pages 731-744.
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Mohammad Masud Iqbal, Atiq Rahman, Zahid Husain, Syed Zaber Mahmud, William G. Ryan & Jacqueline M. Feldman. (2003) Clozapine: A Clinical Review of Adverse Effects and Management. Annals of Clinical Psychiatry 15:1, pages 33-48.
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Michael J. Burns. (2001) The Pharmacology and Toxicology of Atypical Antipsychotic Agents. Journal of Toxicology: Clinical Toxicology 39:1, pages 1-14.
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Articles from other publishers (30)

Ching‐Hua Lin, Hsin‐Yi Lin, Ta‐Chun Lin, Hung‐Yu Chan & Jiahn‐Jyh Chen. (2022) The relation between second‐generation antipsychotics and laxative use in elderly patients with schizophrenia. Psychogeriatrics 22:5, pages 718-727.
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Justin D. Spring, Brittany N. Goldstein, Mason Buster, Ahmed A. Mahmoud & Brandon Hamm. (2022) Physostigmine for Facilitation of Care in Clozapine-Associated Anticholinergic Delirium. Journal of Clinical Psychopharmacology 42:3, pages 329-331.
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Yue Xu, Miaomiao Shao, Xinyu Fang, Wei Tang, Chao Zhou, Xiuxiu Hu, Xiangrong Zhang & Kuan-Pin Su. (2022) Antipsychotic-induced gastrointestinal hypomotility and the alteration in gut microbiota in patients with schizophrenia. Brain, Behavior, and Immunity 99, pages 119-129.
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Yue Xu, Nousayhah Amdanee & Xiangrong Zhang. (2021) Antipsychotic-Induced Constipation: A Review of the Pathogenesis, Clinical Diagnosis, and Treatment. CNS Drugs 35:12, pages 1265-1274.
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Aparna Das, Rebecca Minner, Lewis Krain & John Spollen. (2020) Delirium on clozapine: A tale of friend turned foe-A case report. The International Journal of Psychiatry in Medicine 56:6, pages 446-458.
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Wilmarie Cidre Serrano & Jose Maldonado. (2021) The Use of Physostigmine in the Diagnosis and Treatment of Anticholinergic Toxicity After Olanzapine Overdose: Literature Review and Case Report. Journal of the Academy of Consultation-Liaison Psychiatry 62:3, pages 285-297.
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Susanna Every-Palmer, Stephen J. Inns, Eve Grant & Pete M. Ellis. (2018) Effects of Clozapine on the Gut: Cross-Sectional Study of Delayed Gastric Emptying and Small and Large Intestinal Dysmotility. CNS Drugs 33:1, pages 81-91.
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Bradley L. Demeter & Michael J. Burns. 2017. Critical Care Toxicology. Critical Care Toxicology 907 933 .
Sourav Khanra, Rati Ranjan Sethy, Sanjay Kumar Munda & Christoday Raja Jayant Khess. (2016) An Unusual Case of Delirium after Restarting Clozapine. Clinical Psychopharmacology and Neuroscience 14:1, pages 107-108.
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Bradley L. Demeter & Michael J. Burns. 2016. Critical Care Toxicology. Critical Care Toxicology 1 27 .
Bradley L. Demeter & Michael J. Burns. 2016. Critical Care Toxicology. Critical Care Toxicology 1 27 .
M. A. Savina. (2014) Post stroke delirium. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 114:12. Vyp. 2, pages 19.
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J. Nielsen, P. Damkier, H. Lublin & D. Taylor. (2011) Optimizing clozapine treatment. Acta Psychiatrica Scandinavica 123:6, pages 411-422.
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Tamara G. Fong, Samir R. Tulebaev & Sharon K. Inouye. (2009) Delirium in elderly adults: diagnosis, prevention and treatment. Nature Reviews Neurology 5:4, pages 210-220.
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MICHAEL LEVINE & MICHAEL J. BURNS. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 703 720 .
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Daniel Tarsy, Ross J. Baldessarini & Frank I. Tarazi. (2002) Effects of Newer Antipsychotics on Extrapyramidal Function. CNS Drugs 16:1, pages 23-45.
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Pierre N. Tariot, Carl Salzman, Paul P. Yeung, Joseph Pute & Ihor W. Rak. (2000) Long-term use of quetiapine in elderly patients with psychotic disorders. Clinical Therapeutics 22:9, pages 1068-1084.
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David Reith, Jonathan P. R. Monteleone, Ian M. Whyte, William Ebelling, Nicholas H. G. Holford & Gregory L. Carter. (1998) Features and Toxicokinetics of Clozapine in Overdose. Therapeutic Drug Monitoring 20:1, pages 92-97.
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Sallie Mady, Paul Wax, David Wang, Carla Goetz, Carmen Hadley & Raymond Love. (1996) Pediatric clozapine intoxication. The American Journal of Emergency Medicine 14:5, pages 462-463.
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K. Ikeguchi & A. Kuroda. (1995) Mianserin treatment of patients with psychosis induced by antiparkinsonian drugs. European Archives of Psychiatry and Clinical Neuroscience 244:6, pages 320-324.
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Benoit H. Mulsant & Samuel Gershon. (2004) Neuroleptics in the treatment of psychosis in late life: A rational approach. International Journal of Geriatric Psychiatry 8:12, pages 979-992.
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Christopher J. Ball. (2004) The use of clozapine in older people. International Journal of Geriatric Psychiatry 7:9, pages 689-692.
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