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Clinical Toxicology Volume 18, 1981 - Issue 2
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Research Article

Cardiac Arrhythmias and ECG Abnormalities in Tricyclic Antidepressant Overdose

Robert A. Fasoli Department of Medicine Pulmonary Division, Medical College of Virginia, Richmond, Virginia, 23298
&
Frederick L. Glauser Department of Medicine Pulmonary Division, Medical College of Virginia, Richmond, Virginia, 23298
Pages 155-163 | Published online: 25 Sep 2008

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Alan D. Woolf, Andrew R. Erdman, Lewis S. Nelson, E. Martin Caravati, Daniel J. Cobaugh, Lisa L. Booze, Paul M. Wax, Anthony S. Manoguerra, Elizabeth J. Scharman, Kent R. Olson, Peter A. Chyka, Gwenn Christianson & William G. Troutman. (2007) Tricyclic antidepressant poisoning: an evidence-based consensus guideline for out-of-hospital management. Clinical Toxicology 45:3, pages 203-233.
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Benoit Bailey, Nicholas A. Buckley & Devendra K. Amre. (2004) A Meta‐Analysis of Prognostic Indicators to Predict Seizures, Arrhythmias or Death After Tricyclic Antidepressant Overdose . Journal of Toxicology: Clinical Toxicology 42:6, pages 877-888.
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J.-H. YAN, J. W. HUBBARD, G. McKAY & K. K. MIDHA. (1997) Stereoselective in vivo and in vitro studies on the metabolism of doxepin and N-desmethyldoxepin. Xenobiotica 27:12, pages 1245-1258.
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Kevin S. Merigian, Jerris R. Hedges, Lawrence A. Kaplan, James R. Roberts, Roger C. Stuebing, Amadeo Pesce & Mitchell C. Rashkin. (1991) Plasma Catecholamine Levels In Cyclic Antidepressant Overdose. Journal of Toxicology: Clinical Toxicology 29:2, pages 177-190.
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Articles from other publishers (33)

Ashley Sanello, Marianne Gausche-Hill, William Mulkerin, Karl Sporer, John Brown, Kristi Koenig, Eric Rudnick, Angelo Salvucci & Gregory Gilbert. (2018) Altered Mental Status: Current Evidence-based Recommendations for Prehospital Care. Western Journal of Emergency Medicine 19:3, pages 527-541.
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S Paksu, L Duran, M Altuntas, H Zengin, O Salis, SN Ozsevik, H Albayrak, N Murat, A Guzel & MS Paksu. (2014) Amitriptyline overdose in emergency department of university hospital. Human & Experimental Toxicology 33:9, pages 980-990.
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Michael Levas & Cole Condra. (2011) Paediatric tricyclic antidepressant overdose. Journal of Paramedic Practice 3:12, pages 701-705.
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P Unverir, R Atilla, O Karcioglu, H Topacoglu, Y Demiral & Y Tuncok. (2016) A retrospective analysis of antidepressant poisonings in the emergency department: 11-year experience. Human & Experimental Toxicology 25:10, pages 605-612.
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H K Ruben Thanacoody & Simon H L Thomas. (2005) Tricyclic Antidepressant Poisoning. Toxicological Reviews 24:3, pages 205-214.
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R. Paniagua-Pérez, E. Madrigal-Bujaidar, C.S. Reyes, G.J. Pérez, M.O. Velasco & D. Molina. (2002) Sister chromatid exchanges produced by imipramine and desipramine in mouse bone marrow cells treated in vivo. Toxicology Letters 132:2, pages 123-129.
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Robin B. McFee, Thomas R. Caraccio & Howard C. Mofenson. (2008) Selected Tricyclic Antidepressant Ingestions Involving Children 6 Years Old or Less. Academic Emergency Medicine 8:2, pages 139-144.
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Peter B Richman & Ashraf H Nashed. (1999) The etiology of cardiac arrest in children and young adults: Special considerations for ED management. The American Journal of Emergency Medicine 17:3, pages 264-270.
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Erica L. Liebelt, Andy Ulrich, Paul D. Francis & Alan Woolf. (1997) Serial electrocardiogram changes in acute tricyclic antidepressant overdoses. Critical Care Medicine 25:10, pages 1721-1726.
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C.Keith Stone, Carl M Kraemer, Robert Carroll & Ron Low. (1995) Does a Sodium-Free Buffer Affect QRS Width in Experimental Amitriptyline Overdose?. Annals of Emergency Medicine 26:1, pages 58-64.
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Laura Pimentel & Lori Trommer. (1994) Cyclic Antidepressant Overdoses. Emergency Medicine Clinics of North America 12:2, pages 533-547.
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Erika H. Newton, Richard D. Shih & Robert S. Hoffman. (1994) Cyclic antidepressant overdose: A review of current management strategies. The American Journal of Emergency Medicine 12:3, pages 376-379.
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Linas J Dziukas & Jitu Vohra. (1991) Tricyclic antidepressant poisoning. Medical Journal of Australia 154:5, pages 344-350.
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Scott Krishel & Ken Jackimczyk. (1991) Cyclic Antidepressants, Lithium, and Neuroleptic Agents. Emergency Medicine Clinics of North America 9:1, pages 53-86.
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Stephanie F Gardner, William F Rutherford, Mark A Munger & Edward A Panacek. (1991) Drug-induced supraventricular tachycardia: A case report of fluoxetine. Annals of Emergency Medicine 20:2, pages 194-197.
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Frank W Lavoie, Guy G Gansert & Ronald E Weiss. (1990) Value of initial ECG findings and plasma drug levels in cyclic antidepressant overdose. Annals of Emergency Medicine 19:6, pages 696-700.
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Timothy R Wolfe, E Martin Caravati & Douglas E Rollins. (1989) Terminal 40-ms frontal plane QRS axis as a marker for tricyclic antidepressant overdose. Annals of Emergency Medicine 18:4, pages 348-351.
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S. J. Warrington, C. Padgham & M. Lader. (2009) The cardiovascular effects of antidepressants. Psychological Medicine. Monograph Supplement 16, pages 1-40.
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M. Manoach, D. Varon, M. Neuman & M. Erez. (1989) The cardio-protective features of tricyclic antidepressants. General Pharmacology: The Vascular System 20:3, pages 269-275.
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Paul B. Baker, Kevin S. Merigian, James R. Roberts, Amadeo J. Pesce, Lawrence A. Kaplan & Mitchell C. Rashkin. (1988) Hyperthermia, hypertension, hypertonia, and coma in a massive thioridazine overdose. The American Journal of Emergency Medicine 6:4, pages 346-349.
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Charles L Emerman, Alfred F ConnorsJrJr & Gerald M Burma. (1987) Level of consciousness as a predictor of complications following tricyclic overdose. Annals of Emergency Medicine 16:3, pages 326-330.
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Garrett E Foulke & Timothy E Albertson. (1987) QRS interval in tricyclic antidepressant overdosage: Inaccuracy as a toxicity indicator in emergency settings. Annals of Emergency Medicine 16:2, pages 160-163.
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Garrett E. Foulke, Timothy E. Albertson & William F. Walby. (1986) Tricyclic antidepressant overdose: Emergency department findings as predictors of clinical course. The American Journal of Emergency Medicine 4:6, pages 496-500.
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Steven B McAlphine, Joseph J Calabro, Mel D Robinson & Frederick M BurkleJrJr. (1986) Late death in tricyclic antidepressant overdose revisited. Annals of Emergency Medicine 15:11, pages 1349-1352.
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Peter Crome. (2012) Poisoning Due to Tricyclic Antidepressant Overdosage. Medical Toxicology 1:4, pages 261-285.
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N.J. Braden, J.E. Jackson & P.D. Walson. (1986) Tricyclic Antidepressant Overdose. Pediatric Clinics of North America 33:2, pages 287-297.
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Mark T. Boehnert & Frederick H. LovejoyJr.Jr.. (1985) Value of the QRS Duration versus the Serum Drug Level in Predicting Seizures and Ventricular Arrhythmias after an Acute Overdose of Tricyclic Antidepressants. New England Journal of Medicine 313:8, pages 474-479.
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Michael Callaham. (1985) Epidemiology of fatal tricyclic antidepressant ingestion: implications for management. Annals of Emergency Medicine 14:1, pages 1-9.
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Bentson H. McFarland & Daniel J. Beavers. (1984) Preventive strategies and program evaluation methods for chronically mentally ill suicide attempters. Comprehensive Psychiatry 25:4, pages 426-437.
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John L. Sullivan, Ronald J. Taska, Thomas N. Wise & David M. Goldstein. 1984. Biomedical Psychiatric Therapeutics. Biomedical Psychiatric Therapeutics 25 53 .
Sheldon H. Preskorn & Thomas A. Kent. 1984. Guidelines for the Use of Psychotropic Drugs. Guidelines for the Use of Psychotropic Drugs 63 75 .
Howard C. Herrmann, Lee M. Kaplan & Barbara E. Bierer. (1983) Q-T prolongation and torsades de pointes ventricular tachycardia produced by the tetracyclic antidepressant agent maprotiline. The American Journal of Cardiology 51:5, pages 904-906.
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J.A. Vale & T.J. Meredith. (1982) Poisoning due to psychotropic drugs. Journal of Affective Disorders 4:4, pages 313-329.
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