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Research Article

Tricyclic Antidepressant Overdose: Clinical and Pharmacologic Observations

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Pages 599-613 | Published online: 25 Sep 2008

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Read on this site (9)

Alphonse Poklis Phd, Leslie E. Edinboro, June S. Lee & C. Richard Crooks. (1997) Evaluation of a Colloidal Metal Immunoassay Device for the Detection of Tricyclic Antidepressants in Urine. Journal of Toxicology: Clinical Toxicology 35:1, pages 77-82.
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Bengt-Åke Hultén, Andrew Heath, Kai Knudsen, Gösta Nyberg, Charlotte Svensson & Eric Mårtensson. (1992) Amitriptyline and amitriptyline metabolites in blood and cerebrospinal fluid following human overdose. Journal of Toxicology: Clinical Toxicology 30:2, pages 181-201.
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B-Å Hultén, R. Adams, R. Askenasi, V. Dallos, S. Dawling, G. Volans & A. Heath. (1992) Predicting severity of tricyclic antidepressant overdose. Journal of Toxicology: Clinical Toxicology 30:2, pages 161-170.
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Kevin S. Merigian, Jerris R. Hedges, Lawrence A. Kaplan, James R. Roberts, Roger C. Stuebing, Amadeo Pesce & Mitchell C. Rashkin. (1991) Plasma Catecholamine Levels In Cyclic Antidepressant Overdose. Journal of Toxicology: Clinical Toxicology 29:2, pages 177-190.
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E. Martin Caravati & Philip J. Bossart. (1991) Demographic and Electrocardiographic Factors Associated With Severe Tricyclic Antidepressant Toxicity. Journal of Toxicology: Clinical Toxicology 29:1, pages 31-43.
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Alphonse Poklis, Donna Soghoian, C. Richard Crooks & Joseph J. Saady. (1990) Evaluation of the abbott adx total serum tricyclic immunoassay. Journal of Toxicology: Clinical Toxicology 28:2, pages 235-248.
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Michael Shannon & Frederick H. Lovejoy. (1987) Puimonary Consequences of Severe Tricyclic Anttdepressant Ingestion. Journal of Toxicology: Clinical Toxicology 25:6, pages 443-461.
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Bart Sangster, Gerard de Groot, Cornelius Borst & Dick de Wildt. (1985) Dopamine and Isoproterenol in Imipramine Intoxication in the Dog. Journal of Toxicology: Clinical Toxicology 23:4-6, pages 407-420.
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F. J. Baud, A. Buisine, C. Bismuth, M. Galliot, E. Vicaut, R. Bourdon & P. E. Fournier. (1985) Arterio-Venous Plasma Concentration Differences in Amitriptyline Overdose. Journal of Toxicology: Clinical Toxicology 23:4-6, pages 391-406.
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Articles from other publishers (35)

Justin L. Poklis, Carl E. Wolf, Ashley Goldstein, M. Lauren Wolfe & Alphonse Poklis. (2012) Detection and Quantification of Tricyclic Antidepressants and Other Psychoactive Drugs in Urine by HPLC / MS / MS for Pain Management Compliance Testing . Journal of Clinical Laboratory Analysis 26:4, pages 286-294.
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Thorsten Wittwer & Thorsten Wahlers. (2007) Marginal donor grafts in heart transplantation: lessons learned from 25 years of experience. Transplant International 21:2, pages 113-125.
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D Nicholas Bateman. (2005) Tricyclic Antidepressant Poisoning. Toxicological Reviews 24:3, pages 181-186.
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Yoko Ogawa, Gero Tenderich, Kazutomo Minami, Uwe Schulz, Georg Kleikamp, Lech Hornik, Heinrich Koertke & Reiner Koerfer. (2003) Successful use of a cardiac allograft from tricyclic antidepressant intoxication. Transplantation 76:8, pages 1239-1240.
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Andis Graudins, Robert P Dowsett & Christopher Liddle. (2002) The toxicity of antidepressant poisoning: Is it changing? A comparative study of cyclic and newer serotonin-specific antidepressants. Emergency Medicine Australasia 14:4, pages 440-446.
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David L. Laven & Lisa Oller. (2016) Drug Poisoning and Overdose for the Health Professional: Review of Select Over-the-Counter (OTC) and Prescription Medications. Journal of Pharmacy Practice 13:1, pages 37-81.
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Peter B Richman & Ashraf H Nashed. (1999) The etiology of cardiac arrest in children and young adults: Special considerations for ED management. The American Journal of Emergency Medicine 17:3, pages 264-270.
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T. Paul Tran, Edward A. Panacek, Kenneth J. Rhee & Garrett E. Foulke. (2008) Response to Dopamine vs Norepinephrine in Tricyclic Antidepressant‐induced Hypotension. Academic Emergency Medicine 4:9, pages 864-868.
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P. Taboulet. (1997) Complications cardiovasculaires des convulsions au cours des intoxications par antidépresseurs cycliques. Réanimation Urgences 6:3, pages 297-304.
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Einosuke Tanaka, Masaru Terada, Takako Nakamura, Shogo Misawa & Choei Wakasugi. (1997) Forensic analysis of eleven cyclic antidepressants in human biological samples using a new reversed-phase chromatographic column of 2 μm porous microspherical silica gel. Journal of Chromatography B: Biomedical Sciences and Applications 692:2, pages 405-412.
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Erica L Liebelt, Paul D Francis & Alan D Woolf. (1995) ECG Lead aVR Versus QRS Interval in Predicting Seizures and Arrhythmias in Acute Tricyclic Antidepressant Toxicity. Annals of Emergency Medicine 26:2, pages 195-201.
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Laura Phillips James & Gregory L. Kearns. (2013) Cyclic Antidepressant Toxicity in Children and Adolescents. The Journal of Clinical Pharmacology 35:4, pages 343-350.
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Joyce G. Schwartz, Irene L. Hurd & Joyce J. Carnahan. (1994) Determination of tricyclic antidepressants for ED analysis. The American Journal of Emergency Medicine 12:5, pages 513-516.
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Laura Pimentel & Lori Trommer. (1994) Cyclic Antidepressant Overdoses. Emergency Medicine Clinics of North America 12:2, pages 533-547.
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Erika H. Newton, Richard D. Shih & Robert S. Hoffman. (1994) Cyclic antidepressant overdose: A review of current management strategies. The American Journal of Emergency Medicine 12:3, pages 376-379.
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Alan B. Storrow. (1994) Bupropion overdose and seizure. The American Journal of Emergency Medicine 12:2, pages 183-184.
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Linas J Dziukas & Jitu Vohra. (1991) Tricyclic antidepressant poisoning. Medical Journal of Australia 154:5, pages 344-350.
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Scott Krishel & Ken Jackimczyk. (1991) Cyclic Antidepressants, Lithium, and Neuroleptic Agents. Emergency Medicine Clinics of North America 9:1, pages 53-86.
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G. William Dec & Theodore A. Stern. (2016) Tricyclic Antidepressants in the Intensive Care Unit. Journal of Intensive Care Medicine 5:2, pages 69-81.
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Thomas M. Roy, Miguel A. Ossorio, Lisa M. Cipolla, Cheryl L. Fields, Harvy L. Snider & William H. Anderson. (1989) Pulmonary Complications After Tricyclic Antidepressant Overdose. Chest 96:4, pages 852-856.
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Timothy R Wolfe, E Martin Caravati & Douglas E Rollins. (1989) Terminal 40-ms frontal plane QRS axis as a marker for tricyclic antidepressant overdose. Annals of Emergency Medicine 18:4, pages 348-351.
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S. J. Warrington, C. Padgham & M. Lader. (2009) The cardiovascular effects of antidepressants. Psychological Medicine. Monograph Supplement 16, pages 1-40.
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Michael Shannon, James Merola & Frederick H. LovejoyJrJr. (1988) Hypotension in severe tricyclic antidepressant overdose. The American Journal of Emergency Medicine 6:5, pages 439-442.
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Garrett E Foulke & Timothy E Albertson. (1987) QRS interval in tricyclic antidepressant overdosage: Inaccuracy as a toxicity indicator in emergency settings. Annals of Emergency Medicine 16:2, pages 160-163.
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Helene Denis, Stefano Marullo, Johan Hoebeke & A.Donny Strosberg. (1986) Enzyme-linked immunosorbent assay for amitriptyline and other antidepressants using a monoclonal antibody. Clinica Chimica Acta 159:3, pages 257-267.
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Peter Crome. (2012) Poisoning Due to Tricyclic Antidepressant Overdosage. Medical Toxicology 1:4, pages 261-285.
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N.J. Braden, J.E. Jackson & P.D. Walson. (1986) Tricyclic Antidepressant Overdose. Pediatric Clinics of North America 33:2, pages 287-297.
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D R Jarvie & D Simpson. (2016) Drug Screening: Evaluation of the Toxi-Lab TLC System. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 23:1, pages 76-84.
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Carl Salzman. (1985) Clinical Use of Antidepressant Blood Levels and the Electrocardiogram. New England Journal of Medicine 313:8, pages 512-513.
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Michael Callaham. (1985) Epidemiology of fatal tricyclic antidepressant ingestion: implications for management. Annals of Emergency Medicine 14:1, pages 1-9.
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Patrick J. Commerford & Elwyn A. Lloyd. (1984) Arrhythmias in Patients with Drug Toxicity, Electrolyte, and Endocrine Disturbances. Medical Clinics of North America 68:5, pages 1051-1078.
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Bentson H. McFarland & Daniel J. Beavers. (1984) Preventive strategies and program evaluation methods for chronically mentally ill suicide attempters. Comprehensive Psychiatry 25:4, pages 426-437.
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Bengt‐Åke Hultén & Andrew Heath. (2009) Clinical Aspects of Tricyclic Antidepressant Poisoning. Acta Medica Scandinavica 213:4, pages 275-278.
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J.A. Vale & T.J. Meredith. (1982) Poisoning due to psychotropic drugs. Journal of Affective Disorders 4:4, pages 313-329.
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Tai C. Kwong, Raquel Martinez & Judith M. Keller. (1982) Bonded-phase extraction of plasma tricyclic antidepressant drugs for gas chromatographic analysis. Clinica Chimica Acta 126:2, pages 203-208.
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