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Research Article

Podophyllum Toxicity: A Report of a Fatal Case and a Review of the Literature

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Pages 35-44 | Published online: 25 Sep 2008

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Richard Ko. (2006) Safety of Ethnic & Imported Herbal and Dietary Supplements. Clinical Toxicology 44:5, pages 611-616.
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Articles from other publishers (48)

Qianqian Zhang, Xuemei Li, Xiaoxin Gao, Chunran Cao, Yuchi Hu & Hongzhu Guo. (2021) Total saponins from stems and leaves of Panax quinquefolius L. ameliorate podophyllotoxin‐induced myelosuppression and gastrointestinal toxicity . Biomedical Chromatography 36:2.
Crossref
Ajeet Singh, Ritul Choudhary & Satyaki Ganguly. (2022) Podophyllin in dermatology: Revisiting a historical drug. Indian Dermatology Online Journal 13:1, pages 167.
Crossref
František Zálešák, David Jean-Yves Denis Bon & Jiří Pospíšil. (2019) Lignans and Neolignans: Plant secondary metabolites as a reservoir of biologically active substances. Pharmacological Research 146, pages 104284.
Crossref
Jerry W. Snow, Louise W. Kao & R. Brent Furbee. 2017. Critical Care Toxicology. Critical Care Toxicology 1387 1409 .
Jihui Zhao, Xianghua Piao, Xiaoqin Shi, Aiyong Si, Yongtai Zhang & Nianping Feng. (2016) Podophyllotoxin-Loaded Nanostructured Lipid Carriers for Skin Targeting: In Vitro and In Vivo Studies. Molecules 21:11, pages 1549.
Crossref
Thomas H. PendergastIVIVShane M. HanlonZachary M. LongAlejandro A. RoyoWalter P. Carson. (2016) The legacy of deer overabundance: long-term delays in herbaceous understory recovery. Canadian Journal of Forest Research 46:3, pages 362-369.
Crossref
. 2016. Meyler's Side Effects of Drugs. Meyler's Side Effects of Drugs 844 852 .
Jerry W. Snow, Louise W. Kao & R. Brent Furbee. 2016. Critical Care Toxicology. Critical Care Toxicology 1 23 .
Palaniyandi Karuppaiya & Hsin Sheng Tsay. (2015) Therapeutic values, chemical constituents and toxicity of Taiwanese Dysosma pleiantha – A review. Toxicology Letters 236:2, pages 90-97.
Crossref
Roy Upton, Soaring Bear, David Winston, Daniel Gagnon, Aviva Jill Romm, Tieraona Low Dog, Mary Hardy, Lyle Craker, David Bechtel, Leslie Beyer, Bill J. Gurley, Bill Schoenbart & Constance A. ParksZoё Gardner, Michael McGuffin, Roy Upton, Soaring Bear, David Winston, Daniel Gagnon, Aviva Jill Romm, Tieraona Low Dog, Mary Hardy, Lyle Craker, David Bechtel, Leslie Beyer, Bill J. Gurley, Bill Schoenbart & Constance A. Parks. 2013. American Herbal Products Association’s Botanical Safety. American Herbal Products Association’s Botanical Safety 715 717 .
George E. Burrows & Ronald J. Tyrl. 2012. Toxic Plants of North America. Toxic Plants of North America 257 265 .
Klaus-Peter Wilhelm, Hongbo Zhai & Howard I. MaibachGermaine L. Truisi, Howard I. Maibach & Philip G. Hewitt. 2012. Dermatotoxicology. Dermatotoxicology 43 57 .
Ronald W. McLawhon. 2010. Herbal Supplements. Herbal Supplements 425 442 .
Michelle Forcier & Najah Musacchio. (2010) An overview of human papillomavirus infection for the dermatologist: disease, diagnosis, management, and prevention. Dermatologic Therapy 23:5, pages 458-476.
Crossref
C. Moss & H. Shahidullah. 2010. Rook's Textbook of Dermatology. Rook's Textbook of Dermatology 1 107 .
Donald G. Barceloux. 2008. Medical Toxicology of Natural Substances. Medical Toxicology of Natural Substances 788 791 .
Lorena Baccaglini, Jane C. Atkinson, Lauren L. Patton, Michael Glick, Giuseppe Ficarra & Douglas E. Peterson. (2007) Management of oral lesions in HIV-positive patients. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 103, pages S50.e1-S50.e23.
Crossref
Glenn Kolansky, Christopher Tignanelli, Barry Leshin & Duane Whitaker. 2006. Roenigk's Dermatologic Surgery. Roenigk's Dermatologic Surgery 301 311 .
Giuseppe Del Signore & Otto Mathias Berner. 2006. 541 600 .
. 2006. Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions. Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions 2879 2880 .
Melissa L. Givens & Wilfredo Rivera. (2005) Genital burns from home use of podophyllin. Burns 31:3, pages 394-395.
Crossref
Konnie H. Plumlee. 2004. Clinical Veterinary Toxicology. Clinical Veterinary Toxicology 337 442 .
P. Hewitt & H. I. Maibach. 2004. Condensed Handbook of Occupational Dermatology. Condensed Handbook of Occupational Dermatology 21 36 .
D. J. Atherton & C. Moss. 2004. Rook's Textbook of Dermatology. Rook's Textbook of Dermatology 569 682 .
D. J. Wiley, John Douglas, Karl Beutner, Tom Cox, Kenneth Fife, Anna‐Barbara Moscicki & Lynne Fukumoto. (2002) External Genital Warts: Diagnosis, Treatment, and Prevention. Clinical Infectious Diseases 35:s2, pages S210-S224.
Crossref
E. Longstaff & G. von Krogh. (2001) Condyloma Eradication: Self-Therapy with 0.15–0.5% Podophyllotoxin versus 20–25% Podophyllin Preparations—An Integrated Safety Assessment. Regulatory Toxicology and Pharmacology 33:2, pages 117-137.
Crossref
P. Hewitt & H. I. Maibach. 2000. Handbook of Occupational Dermatology. Handbook of Occupational Dermatology 43 55 .
Ernst SteinErnst Stein. 1998. Proktologie. Proktologie 109 219 .
Acary Souza Bulle Oliveira, Leandro Cortoni Calia, Beatriz Hitomi Kiyomoto, Eliane Focaccia P?voa, Beny Schmidt & Alberto Alain Gabbai. (1996) Acute necrotizing myopathy and podophyllin toxicity: report of a fatal case. Arquivos de Neuro-Psiquiatria 54:2, pages 288-292.
Crossref
J. Handley & W. Dinsmore. (2006) Treatment of anogenital warts. Journal of the European Academy of Dermatology and Venereology 3:3, pages 251-265.
Crossref
Bruce R. Nelson, Glenn Kolansky, Montgomery Gillard, Desiree Ratner & Timothy M. Johnson. (1994) Management of linear verrucous epidermal nevus with topical 5-fluorouracil and tretinoin. Journal of the American Academy of Dermatology 30:2, pages 287-288.
Crossref
I. H. Bowen & I. J. Cubbin. 1993. Adverse Effects of Herbal Drugs 2. Adverse Effects of Herbal Drugs 2 263 273 .
A. Carjuzaa, S. Gosset, J.P. Carpentier, P. Lambreschak, P. Seguin, P. Bernard D'Arbigny, P. Lefebvre, D. Courbier, B. Dupuy & F. Chapon. (1992) Toxicit? syst?mique de la podophylline : a propos d'une ingestion accidentelle mortelle. Revue de la litt?rature. R?animation Urgences 1:5, pages 765-771.
Crossref
Michael T. Goldfarb, Aditya K. Gupta, Madhulika A. Gupta & William S. Sawchuk. (1991) Office Therapy for Human Papillomavirus Infection in Nongenital Sites. Dermatologic Clinics 9:2, pages 287-296.
Crossref
A. Bar-Am, M. Shilon, M.R. Peyser, J. Ophir & S. Brenner. (1991) Treatment of male genital condylomatous lesions by carbon dioxide laser after failure of previous nonlaser methods. Journal of the American Academy of Dermatology 24:1, pages 87-89.
Crossref
T.H.K. Ng, Y.W. Chan, Y.L. Yu, C.M. Chang, H.C. Ho, S.Y. Leung & P.P.H. But. (1991) Encephalopathy and neuropathy following ingestion of a Chinese herbal broth containing podophyllin. Journal of the Neurological Sciences 101:1, pages 107-113.
Crossref
Y. W. Chan. (1991) Magnetic resonance imaging in toxic encephalopathy due to podophyllin poisoning. Neuroradiology 33:4, pages 372-373.
Crossref
Jeffrey Marcus & Charles Camisa. (1990) Podophyllin Therapy for Condyloma Acuminatum. International Journal of Dermatology 29:10, pages 693-698.
Crossref
Darron R. Brown & Kenneth H. Fife. (1990) Human Papillomavirus Infections of the Genital Tract. Medical Clinics of North America 74:6, pages 1455-1485.
Crossref
S. O'Mahony, C. Keohane, J. Jacobs, D. O'Riordain & M. Whelton. (1990) Neuropathy due to podophyllin intoxication. Journal of Neurology 237:2, pages 110-112.
Crossref
Diana R. Holdright & Marjan Jahangiri. (2016) Accidental Poisoning with Podophyllin. Human & Experimental Toxicology 9:1, pages 55-56.
Crossref
K. R. Beutner. 1990. Genital Papillomavirus Infections. Genital Papillomavirus Infections 309 318 .
Michael McGuigan. (1989) Toxicology of topical therapy. Clinics in Dermatology 7:3, pages 32-37.
Crossref
KarlR. Beutner, AlvinE. Friedman-Kien, NitzaN. Artman, MarcusA. Conant, Mark Illeman, RonaldA. Thisted & DannieH. King. (1989) PATIENT-APPLIED PODOFILOX FOR TREATMENT OF GENITAL WARTS. The Lancet 333:8642, pages 831-834.
Crossref
A Edwards, A Atma-Ram & R N Thin. (1988) Podophyllotoxin 0.5% v podophyllin 20% to treat penile warts.. Sexually Transmitted Infections 64:4, pages 263-265.
Crossref
Slanislaw Talalaj & Andrew Czechowicz. (1988) Are herbal remedies safe?. Medical Journal of Australia 148:2, pages 102-103.
Crossref
P.A.G.M. de Smet & A.G. Vulto. 1987. 422 431 .
G. Von Krogh. 1985. Uncommon Infections and Special Topics. Uncommon Infections and Special Topics 175 206 .

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