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Journal of Toxicology: Clinical Toxicology Volume 24, 1986 - Issue 2
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Research Article

Calcium Interferes with the Cardiodepressive Effects of Beta-Blocker Overdose in Isolated Rat Hearts

Johanna Langemeijer Department of Anaesthesiology, St. Antonius Hospital, P.O. Box 2500, 3430, EM Nieuwegein
,
Dick de Wildt Laboratory of Pharmacology, National Institute of Public Health and Environmental Hygiene
,
Gerard de Groot Unit for Pharmacokinetics, National Institute of Public Health and Environmental Hygiene
&
Bart Sangster Department of Reanimation and Clinical Toxicology, University Hospital, Utrecht; The Netherlands National Poison Control Center National Institute of Public Health and Environmental Hygiene, P.O.Box 1, 3720, BA Bilthoven, The Netherlands
Pages 111-133 | Published online: 25 Sep 2008

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Joe-Anthony Rotella, Shaun L. Greene, Zeff Koutsogiannis, Andis Graudins, Yit Hung Leang, Kelvin Kuan, Helen Baxter, Elyssia Bourke & Anselm Wong. (2020) Treatment for beta-blocker poisoning: a systematic review. Clinical Toxicology 58:10, pages 943-983.
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Pierre Taboulet, Alain Cariou, Alain Berdeaux & Chantal Bismuth. (1993) Pathophysiology and Management of Self-Poisoning with Beta-Blockers. Journal of Toxicology: Clinical Toxicology 31:4, pages 531-551.
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Articles from other publishers (9)

Shameen Salam, Brandon Nornhold & Jihad Mallat. (2021) Massive metoprolol overdose requiring ECMO: brief review of the evidence behind recommended treatments. BMJ Case Reports 14:5, pages e232130.
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Andrew T. Young, Matthias J. Merkel, Stephen B. Heitner & Peter M. Schulman. (2015) Focused Echocardiography During Glucagon Administration to Diagnose Beta-Blocker-Induced Cardiomyopathy. Journal of Cardiothoracic and Vascular Anesthesia 29:5, pages 1301-1304.
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Angela C. Anderson. (2008) Management of Beta-Adrenergic Blocker Poisoning. Clinical Pediatric Emergency Medicine 9:1, pages 4-16.
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William KernsIIII. (2007) Management of β-Adrenergic Blocker and Calcium Channel Antagonist Toxicity. Emergency Medicine Clinics of North America 25:2, pages 309-331.
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John O’Grady, Scott Anderson & Derrick Pringle. (2015) Successful treatment of severe atenolol overdose with calcium chloride. CJEM 3:03, pages 224-227.
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Franco Pertoldi, Loris D'Orlando & Willy Pierre Mercante. (1998) Electromechanical Dissociation 48 Hours After Atenolol Overdose: Usefulness of Calcium Chloride. Annals of Emergency Medicine 31:6, pages 777-781.
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William KernsIIII, Mary Ransom, Christian Tomaszewski & Richard Raymond. (2008) The Effect of Hypertonic Sodium and Dantrolene on Propranolol Cardiotoxicity. Academic Emergency Medicine 4:6, pages 545-551.
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William KernsIIII, Jeffrey Kline & Marsha D. Ford. (1994) β-Blocker and Calcium Channel Blocker Toxicity. Emergency Medicine Clinics of North America 12:2, pages 365-390.
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J.J.M. Langemeijer, D.J. de Wildt, G. de Groot & B. Sangster. (1987) Central origin of respiratory arrest in beta-blocker intoxication in rats. Toxicology and Applied Pharmacology 89:3, pages 399-407.
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