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Journal of Toxicology: Clinical Toxicology Volume 25, 1987 - Issue 1-2
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Research Article

A Case of Mao Inhibitor/MDMA Interaction: Agony After Ecstasy

Martin J. Smilkstein Clinical Toxicology and Emergency Medicine Rocky Mountain Poison and Drug Center Denver General Hospital Department of Surgery, Section of Trauma and Emergency Medicine, University of Colorado Health Sciences Center, Denver, Colorado
,
Susan C. Smolinske Information System Rocky Mountain Poison and Drug Center Denver General Hospital, Denver, Colorado
&
Barry H. Rumack University of Colorado Health Sciences Center Rocky Mountain Poison and Drug Center Denver General Hospital, Denver, Colorado
Pages 149-159 | Published online: 25 Sep 2008

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Esther Papaseit, Clara Pérez-Mañá, Marta Torrens, Adriana Farré, Lourdes Poyatos, Olga Hladun, Arantza Sanvisens, Roberto Muga & Magi Farré. (2020) MDMA interactions with pharmaceuticals and drugs of abuse. Expert Opinion on Drug Metabolism & Toxicology 16:5, pages 357-369.
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Kodye L. Abbott, Patrick C. Flannery, Kristina S. Gill, Dawn M. Boothe, Muralikrishnan Dhanasekaran, Sridhar Mani & Satyanarayana R. Pondugula. (2020) Adverse pharmacokinetic interactions between illicit substances and clinical drugs. Drug Metabolism Reviews 52:1, pages 44-65.
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Saskia J. Rietjens, Laura Hondebrink, Remco H. S. Westerink & Jan Meulenbelt. (2012) Pharmacokinetics and pharmacodynamics of 3,4-methylenedioxymethamphetamine (MDMA): interindividual differences due to polymorphisms and drug–drug interactions. Critical Reviews in Toxicology 42:10, pages 854-876.
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Edmund Silins, Jan Copeland & Paul Dillon. (2007) Qualitative review of serotonin syndrome, ecstasy (MDMA) and the use of other serotonergic substances: hierarchy of risk. Australian and New Zealand Journal of Psychiatry 41:8, pages 649-655.
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Gregory S. BarberCharles C. Dike. (2023) Ethical and Practical Considerations for the Use of Psychedelics in Psychiatry. Psychiatric Services 74:8, pages 838-846.
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Aryan Sarparast, Kelan Thomas, Benjamin Malcolm & Christopher S. Stauffer. (2022) Drug-drug interactions between psychiatric medications and MDMA or psilocybin: a systematic review. Psychopharmacology 239:6, pages 1945-1976.
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Funda InanTibor M. Brunt, Ramon R. ContrucciLaura HondebrinkEric J. F. Franssen. (2020) Novel Phenethylamines and Their Potential Interactions With Prescription Drugs: A Systematic Critical Review. Therapeutic Drug Monitoring 42:2, pages 271-281.
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Michael J. Moss & Robert G. Hendrickson. (2019) Serotonin Toxicity. Journal of Clinical Psychopharmacology 39:6, pages 628-633.
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Nicholas J. Connors & Robert S. Hoffman. 2017. Critical Care Toxicology. Critical Care Toxicology 1413 1438 .
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Nicholas J. Connors & Robert S. Hoffman. 2016. Critical Care Toxicology. Critical Care Toxicology 1 26 .
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Donald G. BarcelouxNicholas A. Buckley. 2012. Medical Toxicology of Drug Abuse. Medical Toxicology of Drug Abuse 126 155 .
Shaun L Greene, Fergus Kerr & George Braitberg. (2008) Review article: Amphetamines and related drugs of abuse. Emergency Medicine Australasia 20:5, pages 391-402.
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Helena Carmo, Marc Brulport, Matthias Hermes, Franz Oesch, Douwe de Boer, Fernando Remião, Félix Carvalho, Michael R. Schön, Niels Krebsfaenger, Johannes Doehmer, Maria de Lourdes Bastos & Jan G. Hengstler. (2007) CYP2D6 increases toxicity of the designer drug 4-methylthioamphetamine (4-MTA). Toxicology 229:3, pages 236-244.
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Roland W. Freudenmann & Manfred Spitzer. (2006) The Neuropsychopharmacology and Toxicology of 3,4‐methylenedioxy‐N‐ethyl‐amphetamine (MDEA). CNS Drug Reviews 10:2, pages 89-116.
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Rafael de la Torre, Mag? Farr?Pere N. Roset, Neus Pizarro, Sergio Abanades, Mireia Segura, Jordi Segura & Jordi Cam?. (2004) Human Pharmacology of MDMA. Therapeutic Drug Monitoring 26:2, pages 137-144.
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Jessica R. Oesterheld, Scott C. Armstrong & Kelly L. Cozza. (2004) Ecstasy: Pharmacodynamic and Pharmacokinetic Interactions. Psychosomatics 45:1, pages 84-87.
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J.C. Cole & H.R. Sumnall. (2003) Altered states: the clinical effects of Ecstasy. Pharmacology & Therapeutics 98:1, pages 35-58.
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Elaine Ho, Linda Karimi-Tabesh & Gideon Koren. (2001) Characteristics of pregnant women who use Ecstasy (3, 4-methylenedioxymethamphetamine). Neurotoxicology and Teratology 23:6, pages 561-567.
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MICHAEL SHANNON. (2000) Methylenedioxymethamphetamine (MDMA, “Ecstasy”). Pediatric Emergency Care 16:5, pages 377-380.
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Neil Buxton & Norman S McConachie. (2016) Amphetamine abuse and intracranial haemorrhage. Journal of the Royal Society of Medicine 93:9, pages 472-477.
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Andrew P. Ten Eick, Hidefumi Nakamura & Michael D. Reed. (1998) DRUG–DRUG INTERACTIONS IN PEDIATRIC PSYCHOPHARMACOLOGY. Pediatric Clinics of North America 45:5, pages 1233-1264.
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Paula D Mueller & William S Korey. (1998) Death by “Ecstasy”: The Serotonin Syndrome?. Annals of Emergency Medicine 32:3, pages 377-380.
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Josep Arimany, Jordi Medallo, Amadeu Pujol, Albert Vingut, Juan Carlos Borondo & Juan Luis Valverde. (1998) Intentional Overdose and Death With 3,4-Methylenedioxyethamphetamine (MDEA; "Eve"). The American Journal of Forensic Medicine and Pathology 19:2, pages 148-151.
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Kirk C. Mills. (1997) SEROTONIN SYNDROME. Critical Care Clinics 13:4, pages 763-783.
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Roger Lane & David Baldwin. (1997) Selective Serotonin Reuptake Inhibitor-Induced Serotonin Syndrome. Journal of Clinical Psychopharmacology 17:3, pages 208-221.
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NT Mathew, GE Tietjen & C Lucker. (2016) Serotonin Syndrome Complicating Migraine Pharmacotherapy. Cephalalgia 16:5, pages 323-327.
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A. R. Green, A. J. Cross & G. M. Goodwin. (1995) Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA or “Ecstasy”). Psychopharmacology 119:3, pages 247-260.
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NADIA SOLOWIJ, WAYNE HALL & NICOLE LEE. (2010) Recreational MDMA use in Sydney: a profile of ‘Ecstasy’ users and their experiences with the drug. British Journal of Addiction 87:8, pages 1161-1172.
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Graeme P. Dowling. 1990. Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA. Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA 63 75 .
Alexander T. Shulgin. 1990. Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA. Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA 1 20 .
Jerrold B. Leikin, Anne J. Krantz, Michele Zell-Kanter, Robert L. Barkin & Daniel O. Hryhorczuk. (2012) Clinical Features and Management of Intoxication Due to Hallucinogenic Drugs. Medical Toxicology and Adverse Drug Experience 4:5, pages 324-350.
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