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Journal of Toxicology: Clinical Toxicology Volume 28, 1990 - Issue 3
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Research Article

Clinical experience with the benzodiazepine antagonist flumazenil in suspected benzodiazepine or ethanol poisoning

Frank Martens Reanimationszentrum, Universitätsklinikum Rudolf Virchow, Standort Charlottenburg, Freie Universität Berlin, Spandauer Damm 130, D-1000, Berlin 19, FR Germany
,
Claus Köppel Reanimationszentrum, Universitätsklinikum Rudolf Virchow, Standort Charlottenburg, Freie Universität Berlin, Spandauer Damm 130, D-1000, Berlin 19, FR Germany
,
Prof. Karla Ibe Reanimationszentrum, Universitätsklinikum Rudolf Virchow, Standort Charlottenburg, Freie Universität Berlin, Spandauer Damm 130, D-1000, Berlin 19, FR Germany
,
Angelika Wagemann Landesuntersuchungsinstitut für Lebensmittel, Arzneimittel und Tierseuchen Berlin, Invalidenstratraβe 60, D-1000, Berlin, 21, FR Germany
&
Joachim Tenczer Landesuntersuchungsinstitut für Lebensmittel, Arzneimittel und Tierseuchen Berlin, Invalidenstratraβe 60, D-1000, Berlin, 21, FR Germany
Pages 341-356 | Published online: 25 Sep 2008

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Nasim Zamani, Hossein Hassanian-Moghaddam & Naghmeh Zamani. (2022) Strategies for the treatment of acute benzodiazepine toxicity in a clinical setting: the role of antidotes. Expert Opinion on Drug Metabolism & Toxicology 18:6, pages 367-379.
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Michael Soyka, Henry R. Kranzler, Victor Hesselbrock, Siegfried Kasper, Jochen Mutschler & Hans-Jürgen Möller. (2017) Guidelines for biological treatment of substance use and related disorders, part 1: Alcoholism, first revision. The World Journal of Biological Psychiatry 18:2, pages 86-119.
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John H. Burton, Lawrence Lyon, Todd Dorfman & Anthony J. Tomassoni. (1998) Continuous Flumazenil Infusion in the Treatment of Zolpidem (Ambien®) and Ethanol Coingestion. Journal of Toxicology: Clinical Toxicology 36:7, pages 743-744.
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Articles from other publishers (18)

Mikael Söderqvist, Janne Virta & Antti Kämäräinen. (2018) Substance Abuse Among Emergency Medical Service Patients. Point of Care: The Journal of Near-Patient Testing & Technology 17:2, pages 47-49.
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Elisabeth I Penninga, Niels Graudal, Morten Baekbo Ladekarl & Gesche J?rgens. (2016) Adverse Events Associated with Flumazenil Treatment for the Management of Suspected Benzodiazepine Intoxication - A Systematic Review with Meta-Analyses of Randomised Trials. Basic & Clinical Pharmacology & Toxicology 118:1, pages 37-44.
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Michael Jann, William Klugh Kennedy & Gaylord Lopez. (2014) Benzodiazepines. Journal of Pharmacy Practice 27:1, pages 5-16.
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Neal Benowitz, Brett Roth & Kent Olson. 2007. Addiction and the Medical Complications of Drug Abuse. Addiction and the Medical Complications of Drug Abuse 81 147 .
Adeline Su-Yin Ngo, Charles Rabind Anthony, Miny Samuel, Evelyn Wong & R. Ponampalam. (2007) Should a benzodiazepine antagonist be used in unconscious patients presenting to the emergency department?. Resuscitation 74:1, pages 27-37.
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Neal Benowitz. 2006. Drug Abuse Handbook, Second Edition. Drug Abuse Handbook, Second Edition 597 694 .
. (2005) Part 10.2: Toxicology in ECC. Circulation 112:24_suppl, pages IV-126-IV-132.
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S L Greene, P I Dargan & A L Jones. (2005) Acute poisoning: understanding 90% of cases in a nutshell. Postgraduate Medical Journal 81:954, pages 204-216.
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Frédéric Marrache, Bruno Megarbane, Stéphane Pirnay, Abdel Rhaoui & Marie Thuong. (2016) Difficulties in assessing brain death in a case of benzodiazepine poisoning with persistent cerebral blood flow. Human & Experimental Toxicology 23:10, pages 503-505.
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Alison Jones & Robert Flanagan. 2001. Antidotes. Antidotes 280 286 .
Alison Jones & Robert Flanagan. 2001. Antidotes. Antidotes 165 219 .
Wallace B. Mendelson. (2001) The sleep-inducing effect of ethanol microinjection into the medial preoptic area is blocked by flumazenil. Brain Research 892:1, pages 118-121.
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J. Pronczuk de Garbino. 1997. Applied Toxicology: Approaches Through Basic Science. Applied Toxicology: Approaches Through Basic Science 261 270 .
Papa N Gueye, Jerome R Hoffman, Pierre Taboulet, Eric Vicaut & Frederic J Baud. (1996) Empiric Use of Flumazenil in Comatose Patients: Limited Applicability of Criteria to Define Low Risk. Annals of Emergency Medicine 27:6, pages 730-735.
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G. R. PARK, V. NAVAPURKAR & P. FERENCI. (1995) The role of flumazenil in the critically ill. Acta Anaesthesiologica Scandinavica 39, pages 23-34.
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William H Spivey, James R Roberts & Robert W Derlet. (1993) A clinical trial of escalating doses of flumazenil for reversal of suspected benzodiazepine overdose in the emergency department. Annals of Emergency Medicine 22:12, pages 1813-1821.
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Emilio Gelpi. (1992) Trends in biochemical and biomedical applications of mass spectrometry. International Journal of Mass Spectrometry and Ion Processes 118-119, pages 683-721.
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Emilio Gelpi. 1992. Advances in Mass Spectrometry. Advances in Mass Spectrometry 683 721 .

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