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Research Article

In vitro Skin Irritation Assays: Relevance to Human Skin

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Pages 359-369 | Published online: 25 Sep 2008

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Jeff D. Harvell, Yin-Chieh Tsai, Howard I. Maibach, Roger Gay, Virginia C. Gordon, Karen Miller & Greg C. Mun. (1994) An in Vivo Correlation with Three in Vitro Assays to Assess Skin Irritation Potential. Journal of Toxicology: Cutaneous and Ocular Toxicology 13:2, pages 171-183.
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Articles from other publishers (12)

Xue Ma, Huan Wang, Yanqing Song & Yao Pan. (2020) Skin irritation potential of cosmetic preservatives: An exposure‐relevant study. Journal of Cosmetic Dermatology 20:1, pages 195-203.
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Klaus-Peter Wilhelm, Hongbo Zhai & Howard I. MaibachChantra Eskes, Joao Barroso & David Basketter. 2012. Dermatotoxicology. Dermatotoxicology 284 295 .
Abhijit Chatterjee, R. Jayachandra Babu, M. Klausner & Mandip Singh. (2006) In vitro and in vivo comparison of dermal irritancy of jet fuel exposure using EpiDerm™ (EPI-200) cultured human skin and hairless rats. Toxicology Letters 167:2, pages 85-94.
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Isaak Effendy & Howard I. Maibach. 2006. Irritant Dermatitis. Irritant Dermatitis 249 256 .
Michael Robinson & Mary Perkins. 2005. Handbook of Cosmetic Science and Technology Second Edition. Handbook of Cosmetic Science and Technology Second Edition 683 694 .
K-P. Wilhelm, B. Bottjer & C-P. Siegers. (2001) Quantitative assessment of primary skin irritants in vitro in a cytotoxicity model: comparison with in vivo human irritation tests. British Journal of Dermatology 145:5, pages 709-715.
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Michael K. Robinson, Rosemarie Osborne & Mary A. Perkins. (1999) Strategies for the assessment of acute skin irritation potential. Journal of Pharmacological and Toxicological Methods 42:1, pages 1-9.
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J.N. Lawrence. (1997) Application of in vitro human skin models to dermal irritancy: a brief overview and future prospects. Toxicology in Vitro 11:3, pages 305-312.
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V.A. Deleo, M.P. Carver, J. Hong, K. Fung, B. Kong & S. Desalva. (1996) Arachidonic acid release: An in vitro alternative for dermal irritancy testing. Food and Chemical Toxicology 34:2, pages 167-176.
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Isaak Effendy & Howard I. Maibach. (1996) Detergent and skin irritation. Clinics in Dermatology 14:1, pages 15-21.
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Isaak Effendy & Howard I. Maibach. (2006) Surfactants and experimental irritant contact dermatitis. Contact Dermatitis 33:4, pages 217-225.
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K-P. WILHELM, M. SAMBLEBE & C-P. SIEGERS. (1994) Quantitative in vitro assessment of N-alkyl sulphate-induced cytotoxicity in human keratinocytes (HaCaT). Comparison with in vivo human irritation tests. British Journal of Dermatology 130:1, pages 18-23.
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