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Research Article

Antibody Treatment of Toxin Poisoning Recent Advances

Pages 363-375 | Published online: 25 Sep 2008

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Andrew Kroetsch, Chunxia Qiao, Mairead Heavey, Leiming Guo, Dhaval K. Shah & Sheldon Park. (2019) Engineered pH-dependent recycling antibodies enhance elimination of Staphylococcal enterotoxin B superantigen in mice. mAbs 11:2, pages 411-421.
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Michael Eddleston, Nicolas Fabresse, Adrian Thompson, Ibrahim Al Abdulla, Rachael Gregson, Tim King, Alain Astier, Frederic J. Baud, R Eddie Clutton & Jean-Claude Alvarez. (2018) Anti-colchicine Fab fragments prevent lethal colchicine toxicity in a porcine model: a pharmacokinetic and clinical study. Clinical Toxicology 56:8, pages 773-781.
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David Boels, Jean Francois Hamel, Marie Bretaudeau Deguigne & Patrick Harry. (2012) European viper envenomings: Assessment of Viperfav™ and other symptomatic treatments. Clinical Toxicology 50:3, pages 189-196.
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Articles from other publishers (26)

Marieke A. Dijkman, Femke M. J. Gresnigt & Dylan W. de Lange. (2023) Digoxin-specific antibodies: a novel dosing strategy. Netherlands Heart Journal.
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Andreas H. Laustsen, José María Gutiérrez, Cecilie Knudsen, Kristoffer H. Johansen, Erick Bermúdez-Méndez, Felipe A. Cerni, Jonas A. Jürgensen, Line Ledsgaard, Andrea Martos-Esteban, Mia Øhlenschlæger, Urska Pus, Mikael R. Andersen, Bruno Lomonte, Mikael Engmark & Manuela B. Pucca. (2018) Pros and cons of different therapeutic antibody formats for recombinant antivenom development. Toxicon 146, pages 151-175.
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Rachana D. Sharma, Gajanan D. Katkar, Mahalingam S. Sundaram, Basavarajaiah Swethakumar, Kesturu S. Girish & Kempaiah Kemparaju. (2017) Melatonin inhibits snake venom and antivenom induced oxidative stress and augments treatment efficacy. Acta Tropica 169, pages 14-25.
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Sompong Sapsutthipas, Poh Kuan Leong, Surasak Akesowan, Ronachai Pratanaphon, Nget Hong Tan & Kavi Ratanabanangkoon. (2015) Effective Equine Immunization Protocol for Production of Potent Poly-specific Antisera against Calloselasma rhodostoma, Cryptelytrops albolabris and Daboia siamensis. PLOS Neglected Tropical Diseases 9:3, pages e0003609.
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Alicia Rojas, Mari?ngela Vargas, Nils Ram?rez, Ricardo Estrada, ?lvaro Segura, Mar?a Herrera, Mauren Villalta, Aar?n G?mez, Jos? Mar?a Guti?rrez & Guillermo Le?n. (2013) Role of the animal model on the pharmacokinetics of equine-derived antivenoms. Toxicon 70, pages 9-14.
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A.F. Wahby, El-Sayed M.E. Mahdy, Hatem A. EL-mezayen, Walaa H. Salama, Nihal M. Ebrahim, Azza M. Abdel-Aty & Afaf S. Fahmy. (2012) Role of hyaluronidase inhibitors in the neutralization of toxicity of Egyptian horned viper Cerastes cerastes venom. Journal of Genetic Engineering and Biotechnology 10:2, pages 213-219.
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Alexandra Rucavado, Teresa Escalante, John D. Shannon, Carla N. Ayala-Castro, Mauren Villalta, José María Gutiérrez & Jay W. Fox. (2011) Efficacy of IgG and F(ab′) 2 Antivenoms to Neutralize Snake Venom-induced Local Tissue Damage as Assessed by the Proteomic Analysis of Wound Exudate . Journal of Proteome Research 11:1, pages 292-305.
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Lamia Borchani, Atfa Sassi, Ramla Ben Yekhlef, Ines Safra & Mohamed El Ayeb. (2011) Heminecrolysin, a potential immunogen for monospecific antivenom production against Hemiscorpius lepturus scorpion. Toxicon 58:8, pages 681-688.
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José María Gutiérrez, Guillermo León & Thierry Burnouf. (2011) Antivenoms for the treatment of snakebite envenomings: The road ahead. Biologicals 39:3, pages 129-142.
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E.M. El-Kady, N.M. Ibrahim & A.F. Wahby. (2009) Assessment of the anti-Naja haje antibodies elicited in a low dose multi-site immunization protocol. Toxicon 54:4, pages 450-459.
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Aldon Fernandes, John Oswald Kaundinya, Gautam Daftary, Lalit Saxena, Subhasis Banerjee & Priyabrata Pattnaik. (2008) Chromatographic purification of equine immunoglobulin G F(ab)2 from plasma. Journal of Chromatography B 876:1, pages 109-115.
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Françoise HervéNicolae GhineaPhilippe D’AthisPierre-Alain CarruptJean-Michel Scherrmann. (2008) Covalent Modifications of Antitetanus F ( ab′ ) 2 Fragments with Natural and Synthetic Polyamines and Their Effects on the Antibody Endocytosis in Cultured HL60 Cells . Bioconjugate Chemistry 19:8, pages 1543-1555.
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Rutai Raweerith & Kavi Ratanabanangkoon. (2005) Immunochemical and biochemical comparisons of equine monovalent and polyvalent snake antivenoms. Toxicon 45:3, pages 369-375.
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Robert J Flanagan & Alison L Jones. (2004) Fab Antibody Fragments. Drug Safety 27:14, pages 1115-1133.
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Fernando Chaves, Gilbert D Lor??a, Adriana Salazar & Jos? Mar??a Guti?rrez. (2003) Intramuscular administration of antivenoms in experimental envenomation by Bothrops asper: comparison between Fab and IgG. Toxicon 41:2, pages 237-244.
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Richard F. Clark, Patrick E. McKinney, Peter B. Chase & Frank G. Walter. (2002) Immediate and delayed allergic reactions to Crotalidae polyvalent immune Fab (ovine) antivenom. Annals of Emergency Medicine 39:6, pages 671-676.
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Alison Jones & Robert Flanagan. 2001. Antidotes. Antidotes 96 123 .
G. Le?n, M. Monge, E. Rojas, B. Lomonte & J.M. Guti?rrez. (2001) Comparison between IgG and F(ab?)2 polyvalent antivenoms: neutralization of systemic effects induced by Bothrops asper venom in mice, extravasation to muscle tissue, and potential for induction of adverse reactions. Toxicon 39:6, pages 793-801.
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Guillermo León, Juan Manuel Valverde, Gustavo Rojas, Bruno Lomonte & José Marı́a Gutiérrez. (2000) Comparative study on the ability of IgG and Fab sheep antivenoms to neutralize local hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom. Toxicon 38:2, pages 233-244.
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M. J. Stewart, Vanessa Steenkamp & Michele Zuckerman. (1998) The Toxicology of African Herbal Remedies. Therapeutic Drug Monitoring 20:5, pages 510-516.
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Scott T Milne & Patrick D Meek. (1998) Fatal colchicine overdose: Report of a case and review of the literature. The American Journal of Emergency Medicine 16:6, pages 603-608.
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J.-P. Chippaux & M. Goyffon. (1998) Venoms, antivenoms and immunotherapy. Toxicon 36:6, pages 823-846.
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Stephanie Pépin-Covatta, Charles Lutsch, Michel Grandgeorge & Jean-Michel Scherrmann. (1997) Immunoreactivity of a new generation of horse F(ab′)2 preparations against European viper venoms and the tetanus toxin. Toxicon 35:3, pages 411-422.
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Frédéric J. Baud, Stephen W. Borron, Jean-Michel Scherrmann & Chantal Bismuth. 1997. Applied Toxicology: Approaches Through Basic Science. Applied Toxicology: Approaches Through Basic Science 271 287 .
Stéphanie Pépin-covatta, Charles Lutsch, Michel Grandgeorgefi, Jean Lang & Jean-Michel Scherrmann. (1996) Immunoreactivity and pharmacokinetics of horse anti-scorpion venom F(ab′)2-scorpion venom interactions. Toxicology and Applied Pharmacology 141:1, pages 272-277.
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Ch. Bismuth, F. J. Baud, S. W. Borron & J. M. Scherrmann. 1996. Toxicology - From Cells to Man. Toxicology - From Cells to Man 321 332 .

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