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Research Article

Multiple-Dose Activated Charcoal Compared to Urinary Alkalinization for the Enhancement of Phenobarbital Elimination

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Pages 169-175 | Published online: 25 Sep 2008

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Lotte C. G. Hoegberg, Greene Shepherd, David M. Wood, Jami Johnson, Robert S. Hoffman, E. Martin Caravati, Wui Ling Chan, Silas W. Smith, Kent R. Olson & Sophie Gosselin. (2021) Systematic review on the use of activated charcoal for gastrointestinal decontamination following acute oral overdose. Clinical Toxicology 59:12, pages 1196-1227.
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Robert E. Feldmann$suffix/text()$suffix/text(), Gottfried Kranz, Nicole Praschak-Rieder & Siegfried Kasper. (2009) Psycho-pharmacotherapy for anxiety and obsessive-compulsive disorder: the issue of prolonged barbiturate retention. Current Medical Research and Opinion 25:9, pages 2281-2285.
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A. T. Proudfoot, E. P. Krenzelok & J. A. Vale. (2004) Position Paper on Urine Alkalinization. Journal of Toxicology: Clinical Toxicology 42:1, pages 1-26.
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Ahmet Eroglu, Uzer Kucuktulu, Nesrin Erciyes & Havvanur Turgutalp. (2003) Multiple Dose-Activated Charcoal as a Cause of Acute Appendicitis. Journal of Toxicology: Clinical Toxicology 41:1, pages 71-73.
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Richard Trinder, Thomas Greensmith, Laura Cole & Stefano Cortellini. (2022) The use of haemodialysis for the treatment of phenobarbitone intoxication 30 hours after ingestion. Veterinary Record Case Reports 10:3.
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Kenneth Skov, Niels A. Graudal & Gesche Jürgens. (2021) The effect of activated charcoal on drug exposure following intravenous administration: A meta‐analysis. Basic & Clinical Pharmacology & Toxicology 128:4, pages 568-578.
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Bryan Corbett. 2021. Behavioral Emergencies for Healthcare Providers. Behavioral Emergencies for Healthcare Providers 49 57 .
B Korucu, I Unal, M Pekcan, AC Inkaya, H Yeter, MA Cetinkaya, FF Kaymaz, S Unal, M Akova & Y Erdem. (2019) Ultrastructural evaluation of urine alkalinization versus hydration on colistin-induced nephrotoxicity. Human & Experimental Toxicology 38:12, pages 1366-1377.
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A. Bedet, A. Alestra, D. Vodovar, A. Mekontso Dessap & N. de Prost. (2019) Renal replacement therapy in severe phenobarbital poisoning: Another brick in the wall. Medicina Intensiva (English Edition) 43:7, pages 439-441.
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A. Bedet, A. Alestra, D. Vodovar, A. Mekontso Dessap & N. de Prost. (2019) Renal replacement therapy in severe phenobarbital poisoning: Another brick in the wall. Medicina Intensiva 43:7, pages 439-441.
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Sara Rojas, Nathalie Guillou & Patricia Horcajada. (2019) Ti-Based nanoMOF as an Efficient Oral Therapeutic Agent. ACS Applied Materials & Interfaces 11:25, pages 22188-22193.
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David N. Juurlink. (2016) Activated charcoal for acute overdose: a reappraisal. British Journal of Clinical Pharmacology 81:3, pages 482-487.
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Robert Mactier, Martin Laliberté, Joelle Mardini, Marc Ghannoum, Valery Lavergne, Sophie Gosselin, Robert S. Hoffman & Thomas D. Nolin. (2014) Extracorporeal Treatment for Barbiturate Poisoning: Recommendations From the EXTRIP Workgroup. American Journal of Kidney Diseases 64:3, pages 347-358.
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Barak Cohen, Ido Laish, Tal Brosh-Nissimov, Azik Hoffman, Lior H. Katz, Rony Braunstein, Ram Sagi & Goldman Michael. (2013) Efficacy of urine alkalinization by oral administration of sodium bicarbonate: a prospective open-label trial. The American Journal of Emergency Medicine 31:12, pages 1703-1706.
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Marc Ghannoum & Sophie Gosselin. (2013) Enhanced Poison Elimination in Critical Care. Advances in Chronic Kidney Disease 20:1, pages 94-101.
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James W. Rhee & Timothy P. Young. 2013. Emergency Medicine. Emergency Medicine 1323 1328.e1 .
Timothy E Albertson, Kelly P Owen, Mark E Sutter & Andrew L Chan. (2011) Gastrointestinal decontamination in the acutely poisoned patient. International Journal of Emergency Medicine 4:1.
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Simon W. Lam, Kristin M. Engebretsen & Seth R. Bauer. (2011) Toxicology Today. Journal of Pharmacy Practice 24:2, pages 174-188.
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Lindsay Murray, Frank Daly, Mark Little & Mike Cadogan. 2011. Toxicology Handbook. Toxicology Handbook 127 370 .
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K. FUKUNAGA, M. SAITO, M. MUTO, K. MISHIMA, M. FUJIWARA & K. ORITO. (2008) Effects of urine pH modification on pharmacokinetics of phenobarbital in healthy dogs. Journal of Veterinary Pharmacology and Therapeutics 31:5, pages 431-436.
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Nikolas B. Harbord, Zachary Z. Brener, Donald A. Feinfeld & James F. Winchester. 2008. Therapy in Nephrology & Hypertension. Therapy in Nephrology & Hypertension 1073 1080 .
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DONNA SEGER. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 735 745 .
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T. Syed & M. Cruz. (2006) In Brief: Barbiturate Overdosage. Pediatrics in Review 27:12, pages e81-e82.
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S.V. Mikhalovsky & V.G. Nikolaev. 2006. Activated Carbon Surfaces in Environmental Remediation. Activated Carbon Surfaces in Environmental Remediation 529 561 .
Gina Abbruzzi & Christine M Stork. (2002) Pediatric toxicologic concerns. Emergency Medicine Clinics of North America 20:1, pages 223-247.
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Abdel-Hameed I. Mohammed Ebid & Hana'a M. Abdel-Rahman. (2001) Pharmacokinetics of Phenobarbital During Certain Enhanced Elimination Modalities to Evaluate Their Clinical Efficacy in Management of Drug Overdose. Therapeutic Drug Monitoring 23:3, pages 209-216.
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Biff F. Palmer. (2000) Effectiveness of hemodialysis in the extracorporeal therapy of phenobarbital overdose. American Journal of Kidney Diseases 36:3, pages 640-643.
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Michael P Pietrzak, Edwin K Kuffner, David L Morgan, Christian A Tomaszewski, Stephen V Cantrill, Melody Campbell, Stephen A Colucciello, William C Dalsey, Francis M Fesmiro, E John Gallagher, Theresa A Hackeling, John M Howell, Andy S Jagoda, Stephen KarasJrJr, Thomas W Lukens, David L. Morgan, Barbara A Murphy, Michael P Pietrzak, Daniel G Sayers, Rhonda Whitson, Board Liaison & George W Molzen. (1999) Clinical policy for the initial approach to patients presenting with acute toxic ingestion or dermal or inhalation exposure. Annals of Emergency Medicine 33:6, pages 735-761.
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