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Original Article

Neurological Effects Associated with Use of the Insect Repellent N, N-Diethyl-m-toluamide (DEET)

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Pages 435-441 | Published online: 29 Jul 2009

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Hemlata Pundir, Manish Pant, Tanuja Joshi, Sunaullah Bhat, Ramanand Pathak, Atal Bihari Bajpai, Subhash Chandra & Sushma Tamta. (2023) Identification of essential oil phytocompounds as natural inhibitors of Odorant-binding protein to prevent malaria through in silico approach. Journal of Biomolecular Structure and Dynamics 41:17, pages 8323-8333.
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Jocelyn Rodriguez & Howard I. Maibach. (2016) Percutaneous penetration and pharmacodynamics: Wash-in and wash-off of sunscreen and insect repellent. Journal of Dermatological Treatment 27:1, pages 11-18.
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Daniel L. Sudakin & Wade R. Trevathan. (2003) DEET: A Review and Update of Safety and Risk in the General Population. Journal of Toxicology: Clinical Toxicology 41:6, pages 831-839.
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Lorne Garrettson. (1997) Commentary–DEET: Caution for Children Still Needed. Journal of Toxicology: Clinical Toxicology 35:5, pages 443-445.
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Briana N.C. Chronister, Kun Yang, Audrey R. Yang, Tuo Lin, Xin M. Tu, Dolores Lopez-Paredes, Harvey Checkoway, Jose Suarez-Torres, Sheila Gahagan, Danilo Martinez, Dana Barr, Raeanne C. Moore & Jose R. Suarez-Lopez. (2023) Urinary Glyphosate, 2,4-D and DEET Biomarkers in Relation to Neurobehavioral Performance in Ecuadorian Adolescents in the ESPINA Cohort. Environmental Health Perspectives 131:10.
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Quoc-Bao D. Nguyen, Mai-Anh N. Vu & Adelaide A. Hebert. (2023) Insect repellents: An updated review for the clinician. Journal of the American Academy of Dermatology 88:1, pages 123-130.
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Matthew D. Thum, Nickolaus K. Weise, Riccardo Casalini, Ashley C. Fulton, Andrew P. Purdy & Jeffrey G. Lundin. (2022) Incorporation of N , N ,‐diethyl‐meta‐toluamide within electrospun nylon‐6/6 nanofibers . Journal of Applied Polymer Science 139:48.
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Andrey I Nikiforov & Thomas G Osimitz. (2022) Analysis and interpretation of pharmacokinetic studies following DEET administration to rats, dogs, and humans. Toxicology Research and Application 6, pages 239784732211172.
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D Meisyara, D Tarmadi, A Zulfitri, A Fajar, S K Himmi, T Kartika, I Guswenrivo & S Yusuf. (2021) Repellent activity of three essential oils against dengue and filarial vector mosquitoes. IOP Conference Series: Earth and Environmental Science 918:1, pages 012001.
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Paul M Lantos, Jeffrey Rumbaugh, Linda K Bockenstedt, Yngve T Falck-Ytter, Maria E Aguero-Rosenfeld, Paul G Auwaerter, Kelly Baldwin, Raveendhara R Bannuru, Kiran K Belani, William R Bowie, John A Branda, David B Clifford, Francis J DiMarioJrJr, John J Halperin, Peter J Krause, Valery Lavergne, Matthew H Liang, H Cody Meissner, Lise E Nigrovic, James (Jay) J Nocton, Mikala C Osani, Amy A Pruitt, Jane Rips, Lynda E Rosenfeld, Margot L Savoy, Sunil K Sood, Allen C Steere, Franc Strle, Robert Sundel, Jean Tsao, Elizaveta E Vaysbrot, Gary P Wormser & Lawrence S Zemel. (2021) Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease. Clinical Infectious Diseases 72:1, pages e1-e48.
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Roger D. Lawrie, Robert D. MitchellIIIIII, Anirudh Dhammi, Andrew Wallace, Ernest Hodgson & R. Michael Roe. (2020) Role of long non-coding RNA in DEET- and fipronil-mediated alteration of transcripts associated with Phase I and Phase II xenobiotic metabolism in human primary hepatocytes. Pesticide Biochemistry and Physiology 167, pages 104607.
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Ribhu Gautam, R. Vinu & Prakash Vaithyanathan. (2020) Analytical fast pyrolysis of nitrogen-rich mosquito species via pyrolysis-FTIR and pyrolysis-GC/MS. Journal of Analytical and Applied Pyrolysis 146, pages 104766.
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P V Gonzalez, A Alvarez Costa, L V Harburguer & H M Masuh. (2019) Quantitative Evaluation of the Behavioral Response to Attractant and Repellent Compounds in Anopheles pseudopunctipennis and Aedes aegypti (Diptera: Culicidae) Larvae. Journal of Economic Entomology 112:3, pages 1388-1395.
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G. M. Gomes, J. P. Bigon, F. E. Montoro & L. M. F. Lona. (2018) Encapsulation of N,N ‐diethyl‐ meta ‐toluamide (DEET) via miniemulsion polymerization for temperature controlled release . Journal of Applied Polymer Science 136:9, pages 47139.
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Agustín Alvarez Costa, Paula V Gonzalez, Laura V Harburguer & Héctor M Masuh. (2018) Effects of Temephos, Permethrin, and Eucalyptus nitens Essential Oil on Survival and Swimming Behavior of Aedes aegypti and Anopheles pseudopunctipennis (Diptera: Culicidae) Larvae. Journal of Medical Entomology.
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Daniel Molins-Delgado, Daniel García-Sillero, M. Silvia Díaz-Cruz & Damià Barceló. (2018) On-line solid phase extraction-liquid chromatography-tandem mass spectrometry for insect repellent residue analysis in surface waters using atmospheric pressure photoionization. Journal of Chromatography A 1544, pages 33-40.
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Shovan Dutta, Michael J. Celestine, Supreet Khanal, Alexis Huddleston, Colin Simms, Jessa Faye Arca, Amlan Mitra, Loree Heller, Piotr J. Kraj, Michel Ledizet, John F. Anderson, Girish Neelakanta, Alvin A. Holder & Hameeda Sultana. (2018) Coordination of different ligands to copper(II) and cobalt(III) metal centers enhances Zika virus and dengue virus loads in both arthropod cells and human keratinocytes. Biochimica et Biophysica Acta (BBA) - General Subjects 1862:1, pages 40-50.
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Patrick Fink, Jana Moelzner, Ruediger Berghahn & Eric von Elert. (2017) Do insect repellents induce drift behaviour in aquatic non-target organisms?. Water Research 108, pages 32-38.
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Robert D. MitchellIIIIII, Anirudh Dhammi, Andrew Wallace, Ernest Hodgson & R. Michael Roe. (2016) Impact of Environmental Chemicals on the Transcriptome of Primary Human Hepatocytes: Potential for Health Effects. Journal of Biochemical and Molecular Toxicology 30:8, pages 375-395.
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James H. Diaz. (2016) Chemical and Plant-Based Insect Repellents: Efficacy, Safety, and Toxicity. Wilderness & Environmental Medicine 27:1, pages 153-163.
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Eric von Elert, Katja Preuss & Patrick Fink. (2016) Infodisruption of inducible anti-predator defenses through commercial insect repellents?. Environmental Pollution 210, pages 18-26.
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D. Champakaew, A. Junkum, U. Chaithong, A. Jitpakdi, D. Riyong, R. Sanghong, J. Intirach, R. Muangmoon, A. Chansang, B. Tuetun & B. Pitasawat. (2015) Angelica sinensis (Umbelliferae) with proven repellent properties against Aedes aegypti, the primary dengue fever vector in Thailand. Parasitology Research 114:6, pages 2187-2198.
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Lih-Ming Yiin, Jia-Ni Tian & Chien-Che Hung. (2014) Assessment of dermal absorption of DEET-containing insect repellent and oxybenzone-containing sunscreen using human urinary metabolites. Environmental Science and Pollution Research 22:9, pages 7062-7070.
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E. A. Keziah, E. N. Nukenine, S. P. Y. Danga, L. Younoussa & C. O. Esimone. (2015) Creams Formulated with Ocimum gratissimum L. and Lantana camara L. Crude Extracts and Fractions as Mosquito Repellents Against Aedes aegypti L. (Diptera: Culicidae). Journal of Insect Science 15:1, pages 45-45.
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Jong Kwang Yoon, Kang-Chang Kim, Yeondong Cho, Yong-Dae Gwon, Han Sam Cho, Yoonki Heo, Kihoon Park, Yang-Won Lee, Mijeong Kim, Yu-Kyoung Oh & Young Bong Kim. (2015) Comparison of Repellency Effect of Mosquito Repellents for DEET, Citronella, and Fennel Oil. Journal of Parasitology Research 2015, pages 1-6.
Crossref
Edita E. Revay, Daniel L. Kline, Rui-De Xue, Whitney A. Qualls, Ulrich R. Bernier, Vasiliy D. Kravchenko, Nina Ghattas, Irina Pstygo & G?nter C. M?ller. (2013) Reduction of mosquito biting-pressure: Spatial repellents or mosquito traps? A field comparison of seven commercially available products in Israel. Acta Tropica 127:1, pages 63-68.
Crossref
Philip R. Fischer & Andrea P. Summer. 2013. Principles and Practice of Travel Medicine. Principles and Practice of Travel Medicine 445 462 .
Mark S. Fradin. 2013. Comprehensive Dermatologic Drug Therapy. Comprehensive Dermatologic Drug Therapy 620 628.e3 .
Giuseppe Micali, Stephanie A. St Pierre, Erika E. Reid & Dennis P. West. 2011. Harper's Textbook of Pediatric Dermatology. Harper's Textbook of Pediatric Dermatology.
Jan Schwarzbauer & Mathias Ricking. (2009) Non-target screening analysis of river water as compound-related base for monitoring measures. Environmental Science and Pollution Research 17:4, pages 934-947.
Crossref
T.G. Osimitz, J.V. Murphy, L.A. Fell & B. Page. (2010) Adverse events associated with the use of insect repellents containing N,N-diethyl-m-toluamide (DEET). Regulatory Toxicology and Pharmacology 56:1, pages 93-99.
Crossref
Daniel L. Sudakin & Thomas Osimitz. 2010. Hayes' Handbook of Pesticide Toxicology. Hayes' Handbook of Pesticide Toxicology 2111 2125 .
Carey Pope. 2010. Hayes' Handbook of Pesticide Toxicology. Hayes' Handbook of Pesticide Toxicology 819 835 .
F. Sorge. (2009) Pr?vention par insectifuge chez l?enfant. Archives de P?diatrie 16, pages S115-S122.
Crossref
Günter C. Müller, Amy Junnila, Jerry Butler, Vassiliy D. Kravchenko, Edita E. Revay, Robert W. Weiss & Yosef Schlein. (2009) Efficacy of the botanical repellents geraniol, linalool, and citronella against mosquitoes. Journal of Vector Ecology 34:1, pages 2-8.
Crossref
. 2009. Feigin and Cherry's Textbook of Pediatric Infectious Diseases. Feigin and Cherry's Textbook of Pediatric Infectious Diseases 2325 2380 .
Frank B. Antwi, Leslie M. Shama & Robert K.D. Peterson. (2008) Risk assessments for the insect repellents DEET and picaridin. Regulatory Toxicology and Pharmacology 51:1, pages 31-36.
Crossref
Tracy M. Katz, Jason H. Miller & Adelaide A. Hebert. (2008) Insect repellents: Historical perspectives and new developments. Journal of the American Academy of Dermatology 58:5, pages 865-871.
Crossref
Catherine J. Karr, Gina M. Solomon & Alice C. Brock-Utne. (2007) Health Effects of Common Home, Lawn, and Garden Pesticides. Pediatric Clinics of North America 54:1, pages 63-80.
Crossref
STEPHEN W. BORRON. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 1185 1194 .
Mark S. Fradin. 2007. Wilderness Medicine. Wilderness Medicine 892 904 .
Germain Puccetti. 2006. Insect Repellents. Insect Repellents 353 360 .
Stephen Frances. 2006. Insect Repellents. Insect Repellents 311 326 .
Mustapha Debboun & Sarah Moore. 2006. Insect Repellents. Insect Repellents 3 30 .
Dawn Boudrow Kendrick. (2006) Mosquito repellents and superwarfarin rodenticides – are they really toxic in children?. Current Opinion in Pediatrics 18:2, pages 180-183.
Crossref
Ronald Morton, Michelle Brooks & Nemr Eid. (2006) Hypersensitivity Pneumonitis in a Child Associated with Direct Inhalation Exposure of an Insect Repellant Containing DEET. Pediatric Asthma, Allergy & Immunology 19:1, pages 44-50.
Crossref
Kalapurakkal S. Menon & Amy E. Brown. (2005) Exposure of children to deet and other topically applied insect repellents. American Journal of Industrial Medicine 47:1, pages 91-97.
Crossref
René Csuk, Anja Niesen, Gunther Tschuch & Gerald Moritz. (2004) Synthesis of a natural insect repellent isolated from thrips. Tetrahedron 60:28, pages 6001-6004.
Crossref
Konnie H. Plumlee. 2004. Clinical Veterinary Toxicology. Clinical Veterinary Toxicology 177 192 .
William M. Stauffer, Deepak Kamat & Alan J. Magill. (2006) Traveling with Infants and Children. Part IV: Insect Avoidance and Malaria Prevention. Journal of Travel Medicine 10:4, pages 225-240.
Crossref
John W. Bell, Joseph C. Veltri & Brent C. Page. (2016) Human Exposures to N, N -diethyl- m -toluamide Insect Repellents Reported to the American Association of Poison Control Centers 1993–1997 . International Journal of Toxicology 21:5, pages 341-352.
Crossref
. 2001. Dreisbach's Handbook of Poisoning. Dreisbach's Handbook of Poisoning 133 160 .
A. Banerjee & B. Lagard?re. (2001) Pr?vention du paludisme. Archives de P?diatrie 8, pages 275-277.
Crossref
Raphael J. Leo, Paula A. Del Regno, Charmaine Gregory & Kristin L. Clark. (2001) Insect Repellant Toxicity Associated With Psychosis. Psychosomatics 42:1, pages 78-80.
Crossref
John L. Adgate & Ken Sexton. 2001. Handbook of Pesticide Toxicology. Handbook of Pesticide Toxicology 887 904 .
Carey Pope. 2001. Handbook of Pesticide Toxicology. Handbook of Pesticide Toxicology 873 885 .
N. PETRUCCI & S. SARDINI. (2000) Severe neurotoxic reaction associated with oral ingestion of low-dose diethyltoluamide-containing insect repellent in a child. Pediatric Emergency Care 16:5, pages 341-342.
Crossref
Louis C. Hampers, Elif Oker & Jerrold B. Leikin. (2008) Topical Use of DEET Insect Repellent as a Cause of Severe Encephalopathy in a Healthy Adult Male. Academic Emergency Medicine 6:12, pages 1295-1297.
Crossref
A. Banerjee. (1999) Prise en charge du paludisme de l'enfant, y compris la prévention. Analyse de la bibliographie restreinte à la pédiatrie. Médecine et Maladies Infectieuses 29, pages S142-S163.
Crossref
Alka Gupta, Darshika Nigam, Amita Gupta, G. S. Shukla & A. K. Agarwal. (1999) Effect of pyrethroid‐based liquid mosquito repellent inhalation on the blood–brain barrier function and oxidative damage in selected organs of developing rats. Journal of Applied Toxicology 19:1, pages 67-72.
Crossref

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