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Katrin Skala, Fabio Caputo, Antonio Mirijello, Gabriele Vassallo, Mariangela Antonelli, Anna Ferrulli, Henriette Walter, Otto Lesch & Giovanni Addolorato. (2014)
Sodium oxybate in the treatment of alcohol dependence: from the alcohol withdrawal syndrome to the alcohol relapse prevention. Expert Opinion on Pharmacotherapy 15:2, pages 245-257.
Read now
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Giovanni Addolorato, Lorenzo Leggio, Anna Ferrulli, Fabio Caputo & Antonio Gasbarrini. (2009) The therapeutic potential of gamma-hydroxybutyric acid for alcohol dependence: balancing the risks and benefits. A focus on clinical data. Expert Opinion on Investigational Drugs 18:5, pages 675-686.
Read now
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RobertS. Gable. (2004) Acute Toxic Effects of Club Drugs. Journal of Psychoactive Drugs 36:3, pages 303-313.
Read now
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StevenJ. Lee, Marc Galanter, Helen Dermatis & David McDowell. (2004) Circuit Parties and Patterns of Drug Use in a Subset of Gay Men. Journal of Addictive Diseases 22:4, pages 47-60.
Read now
Read now
Stephen J. Traub, Lewis S. Nelson & Robert S. Hoffman. (2002) Physostigmine as a Treatment for Gamma-Hydroxybutyrate Toxicity: A Review. Journal of Toxicology: Clinical Toxicology 40:6, pages 781-787.
Read now
Read now
A. Dion & S. Jubinville. (1998) Une Nouvelle Méthode Simple Pour Dépister et Quantifier L'Acide Gamma-Hydroxybutyrique (GHB) Dans le Sang et L'Urine Par Chromatographie en Phase Gazeuse. Canadian Society of Forensic Science Journal 31:4, pages 303-312.
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Chantal Bismuth, Sylvain Dally & Stephen W. Borron. (1997) Chemical Submission: GHB, Benzodiazepines, and Other Knock Out Drops. Journal of Toxicology: Clinical Toxicology 35:6, pages 595-598.
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Articles from other publishers (74)
Suryun Jung, Suji Kim, Yujin Seo & Sooyeun Lee. (2021) Metabolic Alterations Associated with γ-Hydroxybutyric Acid and the Potential of Metabolites as Biomarkers of Its Exposure. Metabolites 11:2, pages 101.
Crossref
Crossref
Michael Rath. (2020) Gamma-Butyrolacton - eine Industriechemikalie als Droge. DNP - Der Neurologe & Psychiater 21:6, pages 22-27.
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Crossref
Pouria Jarsiah, Joerg Roehrich, Marek Wyczynski & Cornelius Hess. (2020) Phase I metabolites (organic acids) of gamma‐hydroxybutyric acid–validated quantification using GC–MS and description of endogenous concentration ranges. Drug Testing and Analysis 12:8, pages 1135-1143.
Crossref
Crossref
Jonathan Henssler & Felix Bermpohl. 2018. Handbuch Psychoaktive Substanzen. Handbuch Psychoaktive Substanzen
631
642
.
Boukje A.G. Dijkstra, Rama Kamal, Martijn S. van Noorden, Hein de Haan, Anton J.M. Loonen & Cor A.J. De Jong. (2017) Detoxification with titration and tapering in gamma-hydroxybutyrate (GHB) dependent patients: The Dutch GHB monitor project. Drug and Alcohol Dependence 170, pages 164-173.
Crossref
Crossref
Rama M. Kamal, Martijn S. van Noorden, Ernst Franzek, Boukje A.G. Dijkstra, Anton J.M. Loonen & Cornelius A.J. De Jong. (2016) The Neurobiological Mechanisms of Gamma-Hydroxybutyrate Dependence and Withdrawal and Their Clinical Relevance: A Review. Neuropsychobiology 73:2, pages 65-80.
Crossref
Crossref
Jonathan Henssler & Felix Bermpohl. 2017. Handbuch Psychoaktive Substanzen. Handbuch Psychoaktive Substanzen
1
16
.
Boukje Dijkstra, Arnt Schellekens & Cor de Jong. (2014) GHB-detoxificatie in Nederland. Verslaving 10:3, pages 60-68.
Crossref
Crossref
E. COOPER & J. VERNON. (2013) The effectiveness of pharmacological approaches in the treatment of alcohol withdrawal syndrome (AWS): a literature review. Journal of Psychiatric and Mental Health Nursing 20:7, pages 601-612.
Crossref
Crossref
David B. Horton, David M. Potter & Andy N. Mead. (2013) A translational pharmacology approach to understanding the predictive value of abuse potential assessments. Behavioural Pharmacology 24:5 and 6, pages 410-436.
Crossref
Crossref
Donald G. Barceloux. 2012. Medical Toxicology of Drug Abuse. Medical Toxicology of Drug Abuse
89
109
.
G. Pépin, M. Chèze, G. Hoizey & M. Deveaux. 2012. Traité De Toxicologie Médico-judiciaire. Traité De Toxicologie Médico-judiciaire
569
597
.
Samuel DeMariaJr.Jr.. 2012. Perioperative Addiction. Perioperative Addiction
111
128
.
Nardo Nardocci. 2011. Hyperkinetic Movement Disorders. Hyperkinetic Movement Disorders
563
575
.
Laurent A. Baumes, Mireia Buaki Sogo, Pedro Montes‐Navajas, Avelino Corma & Hermenegildo Garcia. (2010) A Colorimetric Sensor Array for the Detection of the Date‐Rape Drug γ‐Hydroxybutyric Acid (GHB): A Supramolecular Approach. Chemistry – A European Journal 16:15, pages 4489-4495.
Crossref
Crossref
G. Pépin. (2010) Aspects analytique, toxicologique, judiciaire de la soumission chimique : dix ans d’expérience. Annales Pharmaceutiques Françaises 68:2, pages 61-75.
Crossref
Crossref
Francesco Mari, Lucia Politi, Claudia Trignano, Maria Grazia Di Milia, Marianna Di Padua & Elisabetta Bertol. (2009) What constitutes a normal ante-mortem urine GHB concentration?. Journal of Forensic and Legal Medicine 16:3, pages 148-151.
Crossref
Crossref
Babak Mokhlesi & Ryan C. Kamp. 2009. Critical Care Nephrology. Critical Care Nephrology
887
897
.
Enno FreyeEnno Freye. 2010. Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs. Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs
195
198
.
Enno FreyeEnno Freye. 2010. Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs. Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs
191
194
.
Steven Karch. 2008. Karch's Pathology of Drug Abuse, Fourth Edition. Karch's Pathology of Drug Abuse, Fourth Edition
574
607
.
Daniel Kueh, Kazuhiro Iwamoto, Alan Poling & Lisa E. Baker. (2008) Effects of γ-hydroxybutyrate (GHB) and its metabolic precursors on delayed-matching-to-position performance in rats. Pharmacology Biochemistry and Behavior 89:2, pages 179-187.
Crossref
Crossref
Miguel Galicia, Santiago Nogué, Jordi To-Figueras, José-Luís Echarte, M. Luisa Iglesias & Oscar Miró. (2008) Intoxicaciones por éxtasis líquido atendidas en servicios de urgencias hospitalarios de la ciudad de Barcelona durante 2 años. Medicina Clínica 130:7, pages 254-258.
Crossref
Crossref
S. Dresen, J. Kempf & W. Weinmann. (2007) Prevalence of γ-hydroxybutyrate (GHB) in serum samples of amphetamine, metamphetamine and ecstasy impaired drivers. Forensic Science International 173:2-3, pages 112-116.
Crossref
Crossref
John C.M. Brust. 2007. Aspects neurologiques de l'addiction. Aspects neurologiques de l'addiction
245
272
.
Dung Thai, Jo Ellen Dyer, Neal L. Benowitz & Christine A. Haller. (2006) Gamma-hydroxybutyrate and Ethanol Effects and Interactions in Humans. Journal of Clinical Psychopharmacology 26:5, pages 524-529.
Crossref
Crossref
Jessica A. Alexander. (2006) The Potential Hazards of Used and Abused Perioperative Drugs, Herbs, and Dietary Supplements. ASA Refresher Courses in Anesthesiology 34:1, pages 1-19.
Crossref
Crossref
G. Trendelenburg & A. Ströhle. (2005) γ-Hydroxybuttersäure — Neurotransmitter, Medikament und Drogeγ-Hydroxybutyrate — a neurotransmitter, medicine, and drug. Der Nervenarzt 76:7, pages 832-838.
Crossref
Crossref
O. Carter SneadIIIIII & K. Michael Gibson. (2005) γ-Hydroxybutyric Acid. New England Journal of Medicine 352:26, pages 2721-2732.
Crossref
Crossref
Mark E. Dyken & Thoru Yamada. (2005) Narcolepsy and Disorders of Excessive Somnolence. Primary Care: Clinics in Office Practice 32:2, pages 389-413.
Crossref
Crossref
Noriaki Shima, Akihiro Miki, Tooru Kamata, Munehiro Katagi & Hitoshi Tsuchihashi. (2005) Endogenous Level and in Vitro Production of GHB in Blood from Healthy Humans, and the Interpretation of GHB Levels Detected in Antemortem Blood Samples. JOURNAL OF HEALTH SCIENCE 51:2, pages 147-154.
Crossref
Crossref
LAWRENCE S. QUANG, MALHAR C. DESAI, MICHAEL W. SHANNON, ALAN D. WOOLF & TIMOTHY J. MAHER. (2004)
4-Methylpyrazole Decreases 1,4-Butanediol Toxicity by Blocking Its
in Vivo
Biotransformation to γ-Hydroxybutyric Acid
. Annals of the New York Academy of Sciences 1025:1, pages 528-537.
Crossref
Crossref
Cynthia L Morris-Kukoski. (2004) ??-Hydroxybutyrate. Toxicological Reviews 23:1, pages 33-43.
Crossref
Crossref
C Guin Ting Wong, Katherine F Y Chan, K Michael Gibson & O Carter SneadIIIIII. (2004) ??-Hydroxybutyric Acid. Toxicological Reviews 23:1, pages 3-20.
Crossref
Crossref
John C.M. Brust. 2004. Neurological Aspects of Substance Abuse. Neurological Aspects of Substance Abuse
201
224
.
Babak Mokhlesi & Thomas Corbridge. (2003) Toxicology in the critically ill patient. Clinics in Chest Medicine 24:4, pages 689-711.
Crossref
Crossref
Luciano Tedeschi, Mauro A.M Carai, Giampietro Frison, Donata Favretto, Giancarlo Colombo, Santo Davide Ferrara & Gian Luigi Gessa. (2003) Endogenous γ-hydroxybutyric acid is in the rat, mouse and human gastrointestinal tract. Life Sciences 72:22, pages 2481-2488.
Crossref
Crossref
Babak Mokhlesi, Jerrold B. Leikin, Patrick Murray & Thomas C. Corbridge. (2003) Adult Toxicology in Critical Carea. Chest 123:3, pages 897-922.
Crossref
Crossref
Andrea Baldacci, Regula Theurillat, Jitka Caslavska, Helena Pardubská, Rudolf Brenneisen & Wolfgang Thormann. (2003) Determination of γ-hydroxybutyric acid in human urine by capillary electrophoresis with indirect UV detection and confirmation with electrospray ionization ion-trap mass spectrometry. Journal of Chromatography A 990:1-2, pages 99-110.
Crossref
Crossref
Allison A. Muller. (2003) GHB poisoning: Three recent cases reflect the continuing danger. Journal of Emergency Nursing 29:1, pages 72-74.
Crossref
Crossref
Thomas E. Scammell. (2003) The neurobiology, diagnosis, and treatment of narcolepsy. Annals of Neurology 53:2, pages 154-166.
Crossref
Crossref
Phillip E. Mason & William P. KernsIIII. (2008) Gamma Hydroxybutyric Acid (GHB) Intoxication. Academic Emergency Medicine 9:7, pages 730-739.
Crossref
Crossref
L.S Quang, M.W Shannon, A.D Woolf, M.C Desai & T.J Maher. (2002) Pretreatment of CD-1 mice with 4-methylpyrazole blocks toxicity from the gamma-hydroxybutyrate precursor, 1,4-butanediol. Life Sciences 71:7, pages 771-778.
Crossref
Crossref
YOSSEF ITZHAK & SYED F. ALI. (2006) Repeated Administration of Gamma-Hydroxybutyric Acid (GHB) to Mice. Annals of the New York Academy of Sciences 965:1, pages 451-460.
Crossref
Crossref
X. Claramonte, S. Nogué & C. Monsalve. (2002) ¿Nuevas drogas de diseño? ¿Nuevas drogas de síntesis?. FMC - Formación Médica Continuada en Atención Primaria 9:5, pages 323-334.
Crossref
Crossref
Mauro A.M Carai, Roberta Agabio, Carla Lobina, Roberta Reali, Giovanni Vacca, Giancarlo Colombo & Gian Luigi Gessa. (2002) GABAB-receptor mediation of the inhibitory effect of γ-hydroxybutyric acid on intestinal motility in mice. Life Sciences 70:25, pages 3059-3067.
Crossref
Crossref
Christian J. Teter & Sally K. Guthrie. (2012) A Comprehensive Review of MDMA and GHB: Two Common Club Drugs. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 21:12, pages 1486-1513.
Crossref
Crossref
Marco L.A. Sivilotti, Michael J. Burns, Cynthia K. Aaron & Michael J. Greenberg. (2001) Pentobarbital for severe gamma-butyrolactone withdrawal. Annals of Emergency Medicine 38:6, pages 660-665.
Crossref
Crossref
. 2001. Dreisbach's Handbook of Poisoning. Dreisbach's Handbook of Poisoning
508
531
.
Mauro A.M Carai, Giancarlo Colombo, Giuliana Brunetti, Samuele Melis, Salvatore Serra, Giovanni Vacca, Sarah Mastinu, Angelo Maria Pistuddi, Costantino Solinas, Giorgio Cignarella, Giovanna Minardi & Gian Luigi Gessa. (2001) Role of GABAB receptors in the sedative/hypnotic effect of γ-hydroxybutyric acid. European Journal of Pharmacology 428:3, pages 315-321.
Crossref
Crossref
Karen Miotto, Jack Darakjian, Janice Basch, Shanna Murray, Jennifer Zogg & Richard Rawson. (2010) Gamma‐Hydroxybutyric Acid: Patterns of Use, Effects and Withdrawal. The American Journal on Addictions 10:3, pages 232-241.
Crossref
Crossref
Marc A LeBeau, Mark L Miller & Barry Levine. (2001) Effect of storage temperature on endogenous GHB levels in urine. Forensic Science International 119:2, pages 161-167.
Crossref
Crossref
Ecp Yuen. (2017) The Common Drugs of Abuse in Hong Kong. Hong Kong Journal of Emergency Medicine 8:2, pages 90-95.
Crossref
Crossref
Toya M. Bowles, Roger W. Sommi & Mohsen Amiri. (2012) Successful Management of Prolonged γ‐Hydroxybutyrate and Alcohol Withdrawal. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 21:2, pages 254-257.
Crossref
Crossref
Deborah L. Zvosec, Stephen W. Smith, J. Rod McCutcheon, Joe Spillane, Bradley J. Hall & Elizabeth A. Peacock. (2001) Adverse Events, Including Death, Associated with the Use of 1,4-Butanediol. New England Journal of Medicine 344:2, pages 87-94.
Crossref
Crossref
Giampietro Frison, Luciano Tedeschi, Sergio Maietti & Santo Davide Ferrara. (2000) Determination of ?-hydroxybutyric acid (GHB) in plasma and urine by headspace solid-phase microextraction and gas chromatography/positive ion chemical ionization mass spectrometry. Rapid Communications in Mass Spectrometry 14:24, pages 2401-2407.
Crossref
Crossref
MICHAEL SHANNON & LAWRENCE S. QUANG. (2000) Gamma-hydroxybutyrate, gamma-butyrolactone, and 1,4-butanediol: A case report and review of the literature. Pediatric Emergency Care 16:6, pages 435-440.
Crossref
Crossref
O. Carter SneadIIIIII. (2002) Evidence for a G Protein‐Coupled γ‐Hydroxybutyric Acid Receptor. Journal of Neurochemistry 75:5, pages 1986-1996.
Crossref
Crossref
Kimberlie A. Graeme. (2000) NEW DRUGS OF ABUSE. Emergency Medicine Clinics of North America 18:4, pages 625-636.
Crossref
Crossref
Andrew H. Arneson & Janine Goetze. (2000) Dietary supplement or dangerous drug? Two case reports of γ-butyrolactone toxicity. Journal of Emergency Nursing 26:5, pages 425-429.
Crossref
Crossref
Donald H. Jenkins. (2000) SUBSTANCE ABUSE AND WITHDRAWAL IN THE INTENSIVE CARE UNIT. Surgical Clinics of North America 80:3, pages 1033-1053.
Crossref
Crossref
M.Paola Castelli, Ignazia Mocci, Xavier Langlois, Walter Gommeren, Walter H.M.L Luyten, Josée E Leysen & Gian Luigi Gessa. (2000) Quantitative autoradiographic distribution of γ-hydroxybutyric acid binding sites in human and monkey brain. Molecular Brain Research 78:1-2, pages 91-99.
Crossref
Crossref
A. PrioriL. BertolasiA. PesentiA. CappellariS. Barbieri. (2000) γ-Hydroxybutyric acid for alcohol-sensitive myoclonus with dystonia. Neurology 54:8, pages 1706-1706.
Crossref
Crossref
Antonello E Rigamonti & Eugenio E Müller. (2000) Gamma-hydroxybutyric acid and growth hormone secretion Studies in rats and dogs. Alcohol 20:3, pages 293-304.
Crossref
Crossref
M. Moncini, E. Masini, F. Gambassi & P.F. Mannaioni. (2000) Gamma-hydroxybutyric acid and alcohol-related syndromes. Alcohol 20:3, pages 285-291.
Crossref
Crossref
G.P Galloway, S.L Frederick-Osborne, Richard Seymour, Sarah E Contini & David E Smith. (2000) Abuse and therapeutic potential of gamma-hydroxybutyric acid. Alcohol 20:3, pages 263-269.
Crossref
Crossref
Giovanni Addolorato, Fabio Caputo, Esmeralda Capristo, G.Francesco Stefanini & Giovanni Gasbarrini. (2000) Gamma-hydroxybutyric acid Efficacy, potential abuse, and dependence in the treatment of alcohol addiction. Alcohol 20:3, pages 217-222.
Crossref
Crossref
Micheline Schaller, Matteo Schaffhauser, Notker Sans & Bendicht Wermuth. (2001) Cloning and expression of succinic semialdehyde reductase from human brain. European Journal of Biochemistry 265:3, pages 1056-1060.
Crossref
Crossref
Giovanni Addolorato, Giuseppe Balducci, Esmeralda Capristo, Maria L. Attilia, Franco Taggi, Giovanni Gasbarrini & Mauro Ceccanti. (2006) Gamma‐Hydroxybutyric Acid (GHB) in the Treatment of Alcohol Withdrawal Syndrome: A Randomized Comparative Study Versus Benzodiazepine. Alcoholism: Clinical and Experimental Research 23:10, pages 1596-1604.
Crossref
Crossref
Fulvia Berton, Alfredo Brancucci, Franco Beghè, Maurizio Cammalleri, Angelo Demuro, Walter Francesconi & GianLuigi Gessa. (1999) γ-Hydroxybutyrate inhibits excitatory postsynaptic potentials in rat hippocampal slices. European Journal of Pharmacology 380:2-3, pages 109-116.
Crossref
Crossref
Giovanni Addolorato, Esmeralda Capristo, Gian Luigi Gessa, Fabio Caputo, Giuseppe Francesco Stefanini & Giovanni Gasbarrini. (1999) Long-term administration of GHB does not affect muscular mass in alcoholics. Life Sciences 65:14, pages PL191-PL196.
Crossref
Crossref
J.C. Otteni. (1999) Gamma-OH;: un come: un comeback. Annales Françaises d'Anesthésie et de Réanimation 18:4, pages 469-470.
Crossref
Crossref
A. L. Jones. 1999. Yearbook of Intensive Care and Emergency Medicine 1999. Yearbook of Intensive Care and Emergency Medicine 1999
623
632
.
L. Ciolino, M. Mesmer, R. Satzger, A. Machal, H. McCauley & A. Mohrhaus. (1974) The Chemical Interconversion of GHB and GBL: Forensic Issues and Implications. Journal of Forensic Sciences 46:6.
Crossref
Crossref