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Cutaneous and Ocular Toxicology Volume 33, 2014 - Issue 4
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Research Article

The protective effects of dexmedetomidine against apoptosis in retinal ischemia/reperfusion injury in rats

Baran GencerDepartment of Ophthalmology, Faculty of Medicine, Canakkale 18 Mart University CanakkaleTurkeyCorrespondence[email protected]
,
Turan KaracaDepartment of Histology and Embryology, Faculty of Medicine, Trakya University EdirneTurkey
,
Hasan Ali TufanDepartment of Ophthalmology, Faculty of Medicine, Canakkale 18 Mart University CanakkaleTurkey
,
Selçuk KaraDepartment of Ophthalmology, Faculty of Medicine, Canakkale 18 Mart University CanakkaleTurkey
,
Sedat ArikanDepartment of Ophthalmology, Faculty of Medicine, Canakkale 18 Mart University CanakkaleTurkey
,
Huseyin TomanDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Canakkale 18 Mart University CanakkaleTurkey
,
Ihsan KarabogaDepartment of Histology and Embryology, Faculty of Medicine, Trakya University EdirneTurkey
&
Volkan HanciDepartment of Anesthesiology and Reanimation, Faculty of Medicine, 9Eylül University IzmirTurkey
 show all
Pages 283-288 | Received 29 Aug 2013, Accepted 14 Oct 2013, Published online: 11 Feb 2014

Citations (14)

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Youbing Tu, Yubing Liang, Yong Xiao, Jing Lv, Ruicong Guan, Fei Xiao, Yubo Xie & Qiang Xiao. (2019) Dexmedetomidine attenuates the neurotoxicity of propofol toward primary hippocampal neurons in vitro via Erk1/2/CREB/BDNF signaling pathways. Drug Design, Development and Therapy 13, pages 695-706.
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Articles from other publishers (13)

Zhijie Fu, Zhilu Pang, Long He, Le Zhang, Yuning Fan, Can Zhao & Jianjun Yang. (2022) Dexmedetomidine Confers Protection Against Neuronal Oxygen Glucose Deprivation-Reperfusion by Regulating SIRT3 Mediated Autophagy. Neurochemical Research.
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Yang Deng, Yunzhao Fu, Longxiang Sheng, Yixin Hu, Lishi Su, Jiawen Luo, Chun Yan & Wei Chi. (2021) The Regulatory NOD-Like Receptor NLRC5 Promotes Ganglion Cell Death in Ischemic Retinopathy by Inducing Microglial Pyroptosis. Frontiers in Cell and Developmental Biology 9.
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Zhe Wang, Jiali Wu, Zhaolan Hu, Cong Luo, Pengfei Wang, Yanling Zhang & Hui Li. (2020) Dexmedetomidine Alleviates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting p75NTR-Mediated Oxidative Stress and Apoptosis. Oxidative Medicine and Cellular Longevity 2020, pages 1-13.
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Jian-Hua Chang, Mei-Mei Jin & Jun-Tian Liu. (2020) Dexmedetomidine pretreatment protects the heart against apoptosis in ischemia/reperfusion injury in diabetic rats by activating PI3K/Akt signaling in vivo and in vitro. Biomedicine & Pharmacotherapy 127, pages 110188.
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Ping Li, Yongfang Zhang & Hongtao Liu. (2019) The role of Wnt/β-catenin pathway in the protection process by dexmedetomidine against cerebral ischemia/reperfusion injury in rats. Life Sciences 236, pages 116921.
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Yuan‐Qing Wang, Yu‐Feng Tang, Ming‐Kun Yang & Xi‐Zhao Huang. (2018) Dexmedetomidine alleviates cerebral ischemia‐reperfusion injury in rats via inhibition of hypoxia‐inducible factor‐1α . Journal of Cellular Biochemistry 120:5, pages 7834-7844.
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Ran Liu, Xianke Li & Xiangdong Zhang. (2018) Dexmedetomidine protects high-glucose induced apoptosis in human retinal pigment epithelial cells through inhibition on p75(NTR). Biomedicine & Pharmacotherapy 106, pages 466-471.
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Sakiko Kitamura, Kenichi Takechi, Tasuku Nishihara, Amane Konishi, Yasushi Takasaki & Toshihiro Yorozuya. (2018) Effect of dexmedetomidine on intraocular pressure in patients undergoing robot-assisted laparoscopic radical prostatectomy under total intravenous anesthesia: A randomized, double blinded placebo controlled clinical trial. Journal of Clinical Anesthesia 49, pages 30-35.
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Thomas BreuerChristian BleilevensRolf RossaintGernot MarxJulian GehrenkemperHenning DierksenAntoine DelpierreJoachim WeisGhislaine Gayan-RamirezChristian S. Bruells. (2018) Dexmedetomidine Impairs Diaphragm Function and Increases Oxidative Stress but Does Not Aggravate Diaphragmatic Atrophy in Mechanically Ventilated Rats. Anesthesiology 128:4, pages 784-795.
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Zong Chen, Ping-Yang Qiu & Chuan-Gen Ma. (2017) Dexmedetomidine preconditioning protects against retinal ischemia/reperfusion injury and inhibits inflammation response via toll-like receptor 4 (TLR4) pathway. Biomedicine & Pharmacotherapy 93, pages 1018-1024.
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Cong Luo, Ming-Wen Ouyang, Ying-Ying Fang, Shu-Ji Li, Quan Zhou, Jun Fan, Zai-Sheng Qin & Tao Tao. (2017) Dexmedetomidine Protects Mouse Brain from Ischemia-Reperfusion Injury via Inhibiting Neuronal Autophagy through Up-Regulating HIF-1α. Frontiers in Cellular Neuroscience 11.
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Badreldin H. Ali, Turan Karaca, Yousuf Al Suleimani, Mohammed Al Za'abi, Jamila Al Kalbani, Mohammed Ashique & Abderrahim Nemmar. (2017) The effect of swimming exercise on adenine-induced kidney disease in rats, and the influence of curcumin or lisinopril thereon. PLOS ONE 12:4, pages e0176316.
Crossref
Jin Wu & Shi-Tong Li. (2015) Dexmedetomidine May Produce Extra Protective Effects on Sepsis-induced Diaphragm Injury. Chinese Medical Journal 128:10, pages 1407-1411.
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