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Journal of Toxicology: Cutaneous and Ocular Toxicology Volume 8, 1989 - Issue 2
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Research Article

Inhibition of Ultraviolet Radiation-Induced Skin Tumors in Hairless Mice by Topical Application of the Sunscreen 2-Ethyl Hexyl-P-Methoxycinnamate

P. D. Forbes The Center for Photobiology, Temple University Health Sciences Center Philadelphia, Pennsylvania
,
R. E. Davies The Center for Photobiology, Temple University Health Sciences Center Philadelphia, Pennsylvania
,
C. P. Sambuco The Center for Photobiology, Temple University Health Sciences Center Philadelphia, Pennsylvania
&
F. Urbach The Center for Photobiology, Temple University Health Sciences Center Philadelphia, Pennsylvania
Pages 209-226 | Published online: 27 Sep 2008

Citations (26)

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C. P. Sambuco, R. E. Davies, P. D. Forbes & A. M. Hoberman. (1991) Photocarcinogenesis and Consumer Product Testing: Technical Aspects. Toxicology Methods 1:1, pages 75-83.
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Articles from other publishers (25)

Robert E. Osterberg, Christopher P. Sambuco & Paul Donald Forbes. 2013. Nonclinical Safety Assessment. Nonclinical Safety Assessment 393 429 .
G. J. Kapadia, G. S. Rao, J. Takayasu, M. Takasaki, A. Iida, N. Suzuki, T. Konoshima & H. Tokuda. (2013) Evaluation of skin cancer chemoprevention potential of sunscreen agents using the Epstein-Barr virus early antigen activation in vitro assay . International Journal of Cosmetic Science 35:2, pages 143-148.
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JF. Nash. (2006) Human Safety and Efficacy of Ultraviolet Filters and Sunscreen Products. Dermatologic Clinics 24:1, pages 35-51.
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Daniel F. Molefe, James J. Chen, Paul C. Howard, Barbara J. Miller, Christopher P. Sambuco, P. Donald Forbes & Ralph L. Kodell. (2005) Tests for effects on tumor frequency and latency in multiple dosing photococarcinogenicity experiments. Journal of Statistical Planning and Inference 129:1-2, pages 39-58.
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Rachel Haywood, Peter Wardman, Roy Sanders & Claire Linge. (2003) Sunscreens Inadequately Protect Against Ultraviolet-A-Induced Free Radicals in Skin: Implications for Skin Aging and Melanoma?. Journal of Investigative Dermatology 121:4, pages 862-868.
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Antony R. Young. 2002. Melanoma. Melanoma 30 48 .
Honnavara N. Ananthaswamy, Stephen E. Ullrich, Susan M. Loughlin, Polina Khaskina, Margaret L. Kripke, Romano E. Mascotto, Anny Fourtanier & Corazon D. Bucana. (1999) Inhibition of Solar Simulator-Induced p53 Mutations and Protection Against Skin Cancer Development in Mice by Sunscreens. Journal of Investigative Dermatology 112:5, pages 763-768.
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Abigail Jacobs, Javier Avalos, Paul Brown & Jonathan Wilkin. (2016) Does Photosensitivity Predict Photococarcinogenicity?. International Journal of Toxicology 18:3, pages 191-198.
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Francis P. Gasparro, Mark Mitchnick & J. Frank Nash. (2008) A Review of Sunscreen Safety and Efficacy. Photochemistry and Photobiology 68:3, pages 243-256.
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Ronald D. Ley & Anny Fourtanier. (2008) Sunscreen Protection Against Ultraviolet Radiation‐induced Pyrimidine Dimers in Mouse Epidermal DNA. Photochemistry and Photobiology 65:6, pages 1007-1011.
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Lee K. Roberts & Donathan G. Beasley. (1997) Sunscreen lotions prevent ultraviolet radiation-induced suppression of antitumor immune responses. International Journal of Cancer 71:1, pages 94-102.
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Lee K. Roberts & Douglas B. Learn. 1997. Sunscreen Photobiology: Molecular, Cellular and Physiological Aspects. Sunscreen Photobiology: Molecular, Cellular and Physiological Aspects 127 155 .
G. Sauermann, T. Mann & M. Wochnowski. 1997. Skin Cancer and UV Radiation. Skin Cancer and UV Radiation 296 313 .
Herbert Hönigsmann. 1997. Fortschritte der praktischen Dermatologie und Venerologie. Fortschritte der praktischen Dermatologie und Venerologie 255 260 .
Anny Fourtanier. (2008) Mexoryr SX Protects Against Solar‐Simulated UVR‐lnduced Photocarcinogenesis in Mice. Photochemistry and Photobiology 64:4, pages 688-693.
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Rosa Bestak & Gary M. Halliday. (1996) Sunscreens Protect from UV-Promoted Squamous Cell Carcinoma in Mice Chronically Irradiated with Doses of UV Radiation Insufficient to Cause Edema. Photochemistry and Photobiology 64:1, pages 188-193.
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Craig A. Elmets & Cathy Young Anderson. (2008) Sunscreens and Photocarcinogenesis: An Objective Assessment. Photochemistry and Photobiology 63:4, pages 435-440.
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Kane K. Broadbent, Bice S. Martincigh, Mark W. Raynor, Leo F. Salter, Robert Moulder, Per Sjöberg & Karin E. Markides. (1996) Capillary supercritical fluid chromatography combined with atmospheric pressure chemical ionisation mass spectrometry for the investigation of photoproduct formation in the sunscreen absorber 2-ethylhexyl-p-methoxycinnamate. Journal of Chromatography A 732:1, pages 101-110.
Crossref
S.L. Walker, J. Morris, A.C. Chu & A.R. Young. (1994) Relationship between the ability of sunscreens containing 2-ethylhexyl-4′-methoxycinnamate to protect against UVR-induced inflammation, depletion of epidermal Langerhans (Ia+) cells and suppression of alloactivating capacity of murine skin in vivo. Journal of Photochemistry and Photobiology B: Biology 22:1, pages 29-36.
Crossref
P. Donald ForbesChristopher P. SambucoRonald E. Davies. (2016) Photocarcinogenesis Safety Testing. Journal of the American College of Toxicology 12:4, pages 417-424.
Crossref
M. Ashwood‐Smith, C. Stanley, G. H. N. Towers & P. J. Warrington. (2008) UV‐A‐MEDIATED ACTIVITY OF p‐METHOXYMETHYLCINNAMATE. Photochemistry and Photobiology 57:5, pages 814-818.
Crossref
Taj Mohammad & Harry Morrison. (1991) A general approach to the synthesis of 14C-labeled photoactive acrylic acids. Journal of Labelled Compounds and Radiopharmaceuticals 29:9, pages 1019-1026.
Crossref
Taj Mohammad, William M. Baird & Harry Morrison. (1991) Photochemical covalent binding of p-methoxycinnamic acid to calf thymus DNA. Bioorganic Chemistry 19:1, pages 88-100.
Crossref
P. D. Forbes, R. E. Davies & C. P. Sambuco. 1991. Photobiology. Photobiology 663 669 .
R. E. Davies, P. D. Forbes & F. Urbach. 1990. DNA Damage and Repair in Human Tissues. DNA Damage and Repair in Human Tissues 127 135 .

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