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Journal of Toxicology: Toxin Reviews Volume 17, 1998 - Issue 1
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Original Article

The Possible Role of an Active Metafbollte Derived from the Neuroleptic Agent Haloperidol in Drug-Induced Parkinsonism

Kazuo Igarashi Laboratory of Biochemical Toxicology, Faculty of Pharmaceutical Sciences, Kobegakuin University, Ikawadani, Nishi-ku, Kobe, 651-21, Japan
Pages 27-38 | Published online: 02 Jul 2009

Citations (4)

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Read on this site (1)

Etsuko Usuki, Cornelis J. Van Der Schyf & Neal Castagnoli. (1998) Metabolism of Haloperidol and Its Tetrahydropyridine Dehydration Product HPTP. Drug Metabolism Reviews 30:4, pages 809-826.
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Articles from other publishers (3)

Ho-Jin Kang, Sang-Seop Lee, Chung-Hee Lee, Ju-Cheol Shim, Ho Jung Shin, Kwang-Hyeon Liu, Mi-Ae Yoo & Jae-Gook Shin. (2006) NEUROTOXIC PYRIDINIUM METABOLITES OF HALOPERIDOL ARE SUBSTRATES OF HUMAN ORGANIC CATION TRANSPORTERS. Drug Metabolism and Disposition 34:7, pages 1145-1151.
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K. Iwahashi, K. Anemo, K. Nakamura, E. Yoshihara & K. Igarashi. (2000) Analysis of the metabolism of haloperidol (HP) and its neurotoxic pyridinium metabolite (HPP+) in patients with drug-induced parkinsonism. Clinica Chimica Acta 298:1-2, pages 193-195.
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Pierre Voirol, Michèle Jonzier-Perey, François Porchet, Marianne J. Reymond, Robert C. Janzer, Constantin Bouras, Henry W. Strobel, Markus Kosel, Chin B. Eap & Pierre Baumann. (2000) Cytochrome P-450 activities in human and rat brain microsomes. Brain Research 855:2, pages 235-243.
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