Advanced search
Publication Cover
The World Journal of Biological Psychiatry Volume 14, 2013 - Issue 2
Submit an article Journal homepage
257
Views
22
CrossRef citations to date
0
Altmetric
Research Article

The AKT1 gene is associated with attention and brain morphology in schizophrenia

Kazutaka OhiDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan;Core Research for Evolutionary Science and Technology of Japan Science and Technology Agency, Saitama, Japan
,
Ryota HashimotoDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan;Core Research for Evolutionary Science and Technology of Japan Science and Technology Agency, Saitama, Japan;Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, Kanazawa University and Hamamatsu University School of Medicine, Osaka, JapanCorrespondence[email protected]
,
Yuka YasudaDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan;Core Research for Evolutionary Science and Technology of Japan Science and Technology Agency, Saitama, Japan
,
Motoyuki FukumotoDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan;Core Research for Evolutionary Science and Technology of Japan Science and Technology Agency, Saitama, Japan
,
Kiyotaka NemotoDepartment of Neuropsychiatry, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
,
Takashi OhnishiDepartment of Psychosomatic Research, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan
,
Hidenaga YamamoriDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan;Department of Molecular Neuropsychiatry, Osaka University Graduate School of Medicine, Osaka, Japan
,
Hidetoshi TakahashiDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan;Core Research for Evolutionary Science and Technology of Japan Science and Technology Agency, Saitama, Japan
,
Naomi IikeDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan;Core Research for Evolutionary Science and Technology of Japan Science and Technology Agency, Saitama, Japan
,
Kouzin KaminoDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan;National Hospital Organization, Yamato Mental Medical Center, Nara, Japan
,
Tetsuhiko YoshidaDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan
,
Michiyo AzechiDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan
,
Koji IkezawaDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan
,
Hitoshi TanimukaiDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan
,
Shinji TagamiDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan
,
Takashi MoriharaDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan
,
Masayasu OkochiDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan
,
Toshihisa TanakaDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan
,
Takashi KudoDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan
,
Masao IwaseDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan
,
Hiroaki KazuiDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan
&
Masatoshi TakedaDepartment of Psychiatry, Osaka University Graduate school of Medicine, Osaka, Japan;Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, Kanazawa University and Hamamatsu University School of Medicine, Osaka, Japan
 show all
Pages 100-113 | Received 24 Dec 2010, Accepted 24 May 2011, Published online: 12 Dec 2011

Citations (22)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Ashish Kumar Gupta, Ruchika Pokhriyal, Uddipan Das, Mohd Imran Khan, Domada Ratna Kumar, Rishab Gupta, Rakesh Kumar Chadda, Rashmi Ramachandran, Vinay Goyal, Manjari Tripathi & Gururao Hariprasad. (2019) Evaluation of α-synuclein and apolipoprotein E as potential biomarkers in cerebrospinal fluid to monitor pharmacotherapeutic efficacy in dopamine dictated disease states of Parkinson’s disease and schizophrenia. Neuropsychiatric Disease and Treatment 15, pages 2073-2085.
Read now

Articles from other publishers (21)

Kazutaka Ohi, Kentaro Takai, Ayumi Kuramitsu, Shunsuke Sugiyama & Toshiki Shioiri. (2022) Common brain cortical abnormality in smoking behavior and bipolar disorder: discriminant analysis using cortical thickness and surface area. Cerebral Cortex 32:20, pages 4386-4396.
Crossref
Hiroko Kashiwagi, Junya Matsumoto, Kenichiro Miura, Koji Takeda, Yuji Yamada, Michiko Fujimoto, Yuka Yasuda, Hidenaga Yamamori, Manabu Ikeda, Naotsugu Hirabayashi & Ryota Hashimoto. (2022) Neurocognitive features, personality traits, and social function in patients with schizophrenia with a history of violence. Journal of Psychiatric Research 147, pages 50-58.
Crossref
M Fatjó-Vilas, J Soler, M I Ibáñez, J Moya-Higueras, G Ortet, M Guardiola-Ripoll, L Fañanás & B Arias. (2020) The effect of the AKT1 gene and cannabis use on cognitive performance in healthy subjects . Journal of Psychopharmacology 34:9, pages 990-998.
Crossref
Kazutaka Ohi, Chika Sumiyoshi, Haruo Fujino, Yuka Yasuda, Hidenaga Yamamori, Michiko Fujimoto, Tomiki Sumiyoshi & Ryota Hashimoto. (2019) A 1.5-Year Longitudinal Study of Social Activity in Patients With Schizophrenia. Frontiers in Psychiatry 10.
Crossref
Kazutaka Ohi, Chika Sumiyoshi, Haruo Fujino, Yuka Yasuda, Hidenaga Yamamori, Michiko Fujimoto, Tomoko Shiino, Tomiki Sumiyoshi & Ryota Hashimoto. (2018) Genetic Overlap between General Cognitive Function and Schizophrenia: A Review of Cognitive GWASs. International Journal of Molecular Sciences 19:12, pages 3822.
Crossref
Sergey M. Plis, Md Faijul Amin, Adam Chekroud, Devon Hjelm, Eswar Damaraju, Hyo Jong Lee, Juan R. Bustillo, KyungHyun Cho, Godfrey D. Pearlson & Vince D. Calhoun. (2018) Reading the (functional) writing on the (structural) wall: Multimodal fusion of brain structure and function via a deep neural network based translation approach reveals novel impairments in schizophrenia. NeuroImage 181, pages 734-747.
Crossref
Hildegard Janouschek, Claudia R. Eickhoff, Thomas W. Mühleisen, Simon B. Eickhoff & Thomas Nickl-Jockschat. (2018) Using coordinate-based meta-analyses to explore structural imaging genetics. Brain Structure and Function 223:7, pages 3045-3061.
Crossref
Masataka Kikuchi, Kenichiro Miura, Kentaro Morita, Hidenaga Yamamori, Michiko Fujimoto, Masashi Ikeda, Yuka Yasuda, Akihiro Nakaya & Ryota Hashimoto. (2018) Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Scientific Reports 8:1.
Crossref
Kazutaka Ohi, Chika Sumiyoshi, Haruo Fujino, Yuka Yasuda, Hidenaga Yamamori, Michiko Fujimoto, Tomiki Sumiyoshi & Ryota Hashimoto. (2017) A Brief Assessment of Intelligence Decline in Schizophrenia As Represented by the Difference between Current and Premorbid Intellectual Quotient. Frontiers in Psychiatry 8.
Crossref
Elena Shumay, Corinde E. Wiers, Ehsan Shokri-Kojori, Sung Won Kim, Colin A. Hodgkinson, Hui Sun, Dardo Tomasi, Christopher T. Wong, Daniel R. Weinberger, Gene-Jack Wang, Joanna S. Fowler & Nora D. Volkow. (2017) New Repeat Polymorphism in the AKT1 Gene Predicts Striatal Dopamine D2/D3 Receptor Availability and Stimulant-Induced Dopamine Release in the Healthy Human Brain . The Journal of Neuroscience 37:19, pages 4982-4991.
Crossref
Karolina Kozak, Mera S. Barr & Tony P. George. (2017) Traits and Biomarkers for Addiction Risk in Schizophrenia. Current Addiction Reports 4:1, pages 14-24.
Crossref
Mizuki Hino, Yasuto Kunii, Junya Matsumoto, Akira Wada, Atsuko Nagaoka, Shin-ichi Niwa, Hitoshi Takahashi, Akiyoshi Kakita, Hiroyasu Akatsu, Yoshio Hashizume, Sakon Yamamoto & Hirooki Yabe. (2016) Decreased VEGFR2 expression and increased phosphorylated Akt1 in the prefrontal cortex of individuals with schizophrenia. Journal of Psychiatric Research 82, pages 100-108.
Crossref
Yoshihiro Kamada, Ryota Hashimoto, Hidenaga Yamamori, Yuka Yasuda, Tetsuo Takehara, Yuko Fujita, Kenji Hashimoto & Eiji Miyoshi. (2016) Impact of plasma transaminase levels on the peripheral blood glutamate levels and memory functions in healthy subjects. BBA Clinical 5, pages 101-107.
Crossref
Gohar Fakhfouri, Jivan Khlghatyan, Ilya Sukhanov, Raul R. Gainetdinov & Jean-Martin Beaulieu. 2016. Modeling the Psychopathological Dimensions of Schizophrenia - From Molecules to Behavior. Modeling the Psychopathological Dimensions of Schizophrenia - From Molecules to Behavior 447 462 .
Jivan Khlghatyan, Gohar Fakhfouri & Jean-Martin Beaulieu. 2015. Drug Discovery for Schizophrenia. Drug Discovery for Schizophrenia 173 201 .
Kazutaka Ohi, Ryota Hashimoto, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Satomi Umeda-Yano & Masatoshi Takeda. 2015. Neurodegenerative Disorders as Systemic Diseases. Neurodegenerative Disorders as Systemic Diseases 135 155 .
R Hashimoto, M Ikeda, F Yamashita, K Ohi, H Yamamori, Y Yasuda, M Fujimoto, M Fukunaga, K Nemoto, T Takahashi, M Tochigi, T Onitsuka, H Yamasue, K Matsuo, T Iidaka, N Iwata, M Suzuki, M Takeda, K Kasai & N Ozaki. (2014) Common variants at 1p36 are associated with superior frontal gyrus volume. Translational Psychiatry 4:10, pages e472-e472.
Crossref
Motoyuki Fukumoto, Ryota Hashimoto, Kazutaka Ohi, Yuka Yasuda, Hidenaga Yamamori, Satomi Umeda-Yano, Masao Iwase, Hiroaki Kazui & Masatoshi Takeda. (2014) Relation between remission status and attention in patients with schizophrenia. Psychiatry and Clinical Neurosciences 68:3, pages 234-241.
Crossref
Yuka Yasuda. (2014) Cognitive inflexibility in Japanese adolescents and adults with autism spectrum disorders. World Journal of Psychiatry 4:2, pages 42.
Crossref
Kazutaka Ohi, Ryota Hashimoto, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Satomi Umeda-Yano, Masaki Fukunaga, Yoshiyuki Watanabe, Masao Iwase, Hiroaki Kazui & Masatoshi Takeda. (2013) The impact of the genome-wide supported variant in the cyclin M2 gene on gray matter morphology in schizophrenia. Behavioral and Brain Functions 9:1.
Crossref
Robert E. Featherstone, Valerie M.Tatard-Leitman, Jimmy D. Suh, Robert Lin, Irwin Lucki & Steven J. Siegel. (2013) Electrophysiological and behavioral responses to ketamine in mice with reduced Akt1 expression. Psychopharmacology 227:4, pages 639-649.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.