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Nanotoxicology Volume 6, 2012 - Issue 8
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Research Article

TiO2 nanoparticles induce insulin resistance in liver-derived cells both directly and via macrophage activation

Diana GurevitchDepartment of Environmental Sciences, The Weizmann Institute of Science, Rehovot, Israel
,
Timor Shuster-MeiselesDepartment of Environmental Sciences, The Weizmann Institute of Science, Rehovot, Israel
,
Ori NovDepartment of Clinical Biochemistry, National Institute of Biotechnology in the Negev, Ben-Gurion University, Beer-Sheva, Israel
,
Yehiel ZickDepartment of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot, Israel
,
Assaf RudichDepartment of Clinical Biochemistry, National Institute of Biotechnology in the Negev, Ben-Gurion University, Beer-Sheva, Israel;Department of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot, Israel
&
Yinon RudichDepartment of Environmental Sciences, The Weizmann Institute of Science, Rehovot, IsraelCorrespondence[email protected]
Pages 804-812 | Received 01 Mar 2011, Accepted 25 Jul 2011, Published online: 18 Oct 2011

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Leah K. Bartel, Daniel A. Hunter, Kayla B. Anderson, W. Yau, Ji Wu & Worlanyo E. Gato. (2019) Short-term evaluation of hepatic toxicity of titanium dioxide nanofiber (TDNF). Drug and Chemical Toxicology 42:1, pages 35-42.
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Anissa Zergui. (2023) Metallic nanoparticles in food: An overview on consumers’ health effects. Food and Humanity 1, pages 51-56.
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Xiaojie Lin, Yan Fang, Xuechao Jin, Mingming Zhang & Kai Shi. (2021) Modulating Repolarization of Tumor-Associated Macrophages with Targeted Therapeutic Nanoparticles as a Potential Strategy for Cancer Therapy. ACS Applied Bio Materials 4:8, pages 5871-5896.
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Zapór Lidia. (2021) Zaburzenia funkcjonowania układu hormonalnego człowieka powodowane przez nanomateriały. Occupational Safety – Science and Practice 592:1, pages 11-13.
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Ayushi Priyam, Pushplata Prasad Singh & Shweta Gehlout. (2018) Role of Endocrine-Disrupting Engineered Nanomaterials in the Pathogenesis of Type 2 Diabetes Mellitus. Frontiers in Endocrinology 9.
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Gui Chen, Yuexin Shen, Xiyue Li, Qin Jiang, Shanshan Cheng, Yuxiu Gu, Liangliang Liu & Yi Cao. (2017) The endoplasmic reticulum stress inducer thapsigargin enhances the toxicity of ZnO nanoparticles to macrophages and macrophage-endothelial co-culture. Environmental Toxicology and Pharmacology 50, pages 103-110.
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Xuefei Lu, Yong Zhu & Tao Zhu. 2017. Adverse Effects of Engineered Nanomaterials. Adverse Effects of Engineered Nanomaterials 339 355 .
Yongqiang Zhang, Yangsheng Lin, Xi Li, Li Zhang, Wei Pan, Huili Zhu, Zhuge Xi & Danfeng Yang. (2016) Silica dioxide nanoparticles combined with cold exposure induce stronger systemic inflammatory response. Environmental Science and Pollution Research 24:1, pages 291-298.
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Hailong Hu, Li Li, Qian Guo, Sanli Jin, Ying Zhou, Yuri Oh, Yujie Feng, Qiong Wu & Ning Gu. (2016) A mechanistic study to increase understanding of titanium dioxide nanoparticles-increased plasma glucose in mice. Food and Chemical Toxicology 95, pages 175-187.
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Hailong Hu, Qian Guo, Changlin Wang, Xiao Ma, Hongjuan He, Yuri Oh, Yujie Feng, Qiong Wu & Ning Gu. (2015) Titanium dioxide nanoparticles increase plasma glucose via reactive oxygen species-induced insulin resistance in mice. Journal of Applied Toxicology 35:10, pages 1122-1132.
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Sotirios Maipas & Polyxeni Nicolopoulou-Stamati. (2015) Sun lotion chemicals as endocrine disruptors. Hormones 14:1, pages 32-46.
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Nan Chen, Hui Wang, Qing Huang, Jiang Li, Juan Yan, Dannong He, Chunhai Fan & Haiyun Song. (2014) Long‐Term Effects of Nanoparticles on Nutrition and Metabolism. Small 10:18, pages 3603-3611.
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Michal Pardo, Timor Shuster-Meiseles, Smadar Levin-Zaidman, Assaf Rudich & Yinon Rudich. (2014) Low Cytotoxicity of Inorganic Nanotubes and Fullerene-Like Nanostructures in Human Bronchial Epithelial Cells: Relation to Inflammatory Gene Induction and Antioxidant Response. Environmental Science & Technology 48:6, pages 3457-3466.
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Ivo Iavicoli, Luca Fontana, Veruscka Leso & Antonio Bergamaschi. (2013) The Effects of Nanomaterials as Endocrine Disruptors. International Journal of Molecular Sciences 14:8, pages 16732-16801.
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