1,486
Views
122
CrossRef citations to date
0
Altmetric
Original Article

Translocation of differently sized and charged polystyrene nanoparticles in in vitro intestinal cell models of increasing complexity

, , , , , , & show all
Pages 453-461 | Received 13 May 2014, Accepted 07 Jul 2014, Published online: 05 Aug 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Qingying Shi, Jingchun Tang, Rutao Liu & Lan Wang. (2022) Toxicity in vitro reveals potential impacts of microplastics and nanoplastics on human health: A review. Critical Reviews in Environmental Science and Technology 52:21, pages 3863-3895.
Read now
Siyue Wen, Yu Zhao, Mengqi Wang, Hongbin Yuan & Hengyi Xu. (2022) Micro(nano)plastics in food system: potential health impacts on human intestinal system. Critical Reviews in Food Science and Nutrition 0:0, pages 1-19.
Read now
Kornphimol Kulthong, Guido J. E. J. Hooiveld, Loes P. M. Duivenvoorde, Ignacio Miro Estruch, Hans Bouwmeester & Meike van der Zande. (2021) Comparative study of the transcriptomes of Caco-2 cells cultured under dynamic vs. static conditions following exposure to titanium dioxide and zinc oxide nanomaterials. Nanotoxicology 15:9, pages 1233-1252.
Read now
Cuizhu Ma, Qiqing Chen, Jiawei Li, Bowen Li, Weiwenhui Liang, Lei Su & Huahong Shi. (2021) Distribution and translocation of micro- and nanoplastics in fish. Critical Reviews in Toxicology 51:9, pages 740-753.
Read now
K. Tallec, I. Paul-Pont, M. Boulais, N. Le Goïc, C. González-Fernández, F. Le Grand, A. Bideau, C. Quéré, A.-L. Cassone, C. Lambert, P. Soudant & A. Huvet. (2020) Nanopolystyrene beads affect motility and reproductive success of oyster spermatozoa (Crassostrea gigas). Nanotoxicology 14:8, pages 1039-1057.
Read now
Laura Rubio, Ricard Marcos & Alba Hernández. (2020) Potential adverse health effects of ingested micro- and nanoplastics on humans. Lessons learned from in vivo and in vitro mammalian models. Journal of Toxicology and Environmental Health, Part B 23:2, pages 51-68.
Read now
Ashraf Abdelkhaliq, Meike van der Zande, Anna K. Undas, Ruud J. B. Peters & Hans Bouwmeester. (2020) Impact of in vitro digestion on gastrointestinal fate and uptake of silver nanoparticles with different surface modifications. Nanotoxicology 14:1, pages 111-126.
Read now
Holger Sieg, Caroline Braeuning, Birgitta Maria Kunz, Hannes Daher, Claudia Kästner, Benjamin-Christoph Krause, Thomas Meyer, Pégah Jalili, Kevin Hogeveen, Linda Böhmert, Dajana Lichtenstein, Agnès Burel, Soizic Chevance, Harald Jungnickel, Jutta Tentschert, Peter Laux, Albert Braeuning, Fabienne Gauffre, Valérie Fessard, Jan Meijer, Irina Estrela-Lopis, Andreas F. Thünemann, Andreas Luch & Alfonso Lampen. (2018) Uptake and molecular impact of aluminum-containing nanomaterials on human intestinal caco-2 cells. Nanotoxicology 12:9, pages 992-1013.
Read now
Zhongyuan Guo, Nicole J. Martucci, Yizhong Liu, Eusoo Yoo, Elad Tako & Gretchen J. Mahler. (2018) Silicon dioxide nanoparticle exposure affects small intestine function in an in vitro model. Nanotoxicology 12:5, pages 485-508.
Read now

Articles from other publishers (113)

Nailul Muthiati Rahmatin, Agoes Soegianto, Bambang Irawan, Carolyn Melissa Payus, Khudrotul Nisa Indriyasari, Ary Marchellina, Wildanun Mukholladun & Yulia Irnidayanti. (2024) The spatial distribution and physico-chemical characteristic of microplastics in the sediment and cockle (Anadara granosa) from the coastal waters of East Java, Indonesia, and the health hazards associated with cockle consumption. Marine Pollution Bulletin 198, pages 115906.
Crossref
Nurshad Ali, Jenny Katsouli, Emma L. Marczylo, Timothy W. Gant, Stephanie Wright & Jorge Bernardino de la Serna. (2024) The potential impacts of micro-and-nano plastics on various organ systems in humans. eBioMedicine 99, pages 104901.
Crossref
Anju Sharma, Manjyot Kaur, Kirti Sharma, Suresh kumar Bunkar, Placheril John & Pradeep Bhatnagar. (2023) Nano polystyrene induced changes in anxiety and learning behaviour are mediated through oxidative stress and gene disturbance in mouse brain regions. NeuroToxicology 99, pages 139-151.
Crossref
Enkeleda Meziu, Kristela Shehu, Marcus Koch, Marc Schneider & Annette Kraegeloh. (2023) Impact of mucus modulation by N-acetylcysteine on nanoparticle toxicity. International Journal of Pharmaceutics: X 6, pages 100212.
Crossref
Jiwon Choi, Yeowool Choi & Sang Don Kim. (2023) Body distribution and ecotoxicological effect of nanoplastics in freshwater fish, Zacco platypus. Chemosphere 341, pages 140107.
Crossref
M. Raju, R. Gandhimathi & P.V. Nidheesh. (2023) The cause, fate and effect of microplastics in freshwater ecosystem: Ways to overcome the challenge. Journal of Water Process Engineering 55, pages 104199.
Crossref
Jiin Eom, Arslan Sarwar, Eun Cheol Lee, Gwang-Bum Im, Sung-Won Kim, Linh Thanh Nguyen, Jeong-Bin Moon, Soong Ho Um, Gi-Ra Yi, Eun Yeol Lee & Suk Ho Bhang. (2023) Cytotoxic effect and mechanism of nano-sized polystyrene degraded by Rhodococcus ruber C208. Chemical Engineering Journal 473, pages 145094.
Crossref
Jyoti Rawat, Vikas Kumar, Priyanca Ahlawat, Lokesh Kumar Tripathi, Richa Tomar, Rohit Kumar, Sunny Dholpuria & Piyush Kumar Gupta. (2023) Current Trends on the Effects of Metal-Based Nanoparticles on Microbial Ecology. Applied Biochemistry and Biotechnology 195:10, pages 6168-6182.
Crossref
Kwon-Hong Lee, Jin-Hyoung Kim, Kyu-Sik Shin, Cheol-Ung Cha & Hyung-Min Lee. (2023) Complementary Multisplit Ring Resonant MEMS Sensor With Microfilter for Microplastics Concentration Measurement. IEEE Sensors Journal 23:17, pages 19105-19116.
Crossref
Clara Mancuso, Eric Tremblay, Elisa Gnodi, Steve Jean, Jean-François Beaulieu & Donatella Barisani. (2023) The Combination of Gold and Silver Food Nanoparticles with Gluten Peptides Alters the Autophagic Pathway in Intestinal Crypt-like Cells. International Journal of Molecular Sciences 24:17, pages 13040.
Crossref
Maxi B. Paul, Linda Böhmert, I-Lun Hsiao, Albert Braeuning & Holger Sieg. (2023) Complex intestinal and hepatic in vitro barrier models reveal information on uptake and impact of micro-, submicro- and nanoplastics. Environment International, pages 108172.
Crossref
Chelsea Cary & Phoebe Stapleton. (2023) Determinants and mechanisms of inorganic nanoparticle translocation across mammalian biological barriers. Archives of Toxicology 97:8, pages 2111-2131.
Crossref
Yu Wu, Xiaochao Tan, Xian Shi, Peiyu Han & Huanliang Liu. (2023) Combined Effects of Micro- and Nanoplastics at the Predicted Environmental Concentration on Functional State of Intestinal Barrier in Caenorhabditis elegans. Toxics 11:8, pages 653.
Crossref
Paola Pontecorvi, Simona Ceccarelli, Fabrizio Cece, Simona Camero, Lavinia Vittoria Lotti, Elena Niccolai, Giulia Nannini, Giulia Gerini, Eleni Anastasiadou, Elena Sofia Scialis, Enrico Romano, Mary Anna Venneri, Amedeo Amedei, Antonio Angeloni, Francesca Megiorni & Cinzia Marchese. (2023) Assessing the Impact of Polyethylene Nano/Microplastic Exposure on Human Vaginal Keratinocytes. International Journal of Molecular Sciences 24:14, pages 11379.
Crossref
Javad Bazeli, Zarrin Banikazemi, Michael R. Hamblin & Reza Sharafati Chaleshtori. (2023) Could probiotics protect against human toxicity caused by polystyrene nanoplastics and microplastics?. Frontiers in Nutrition 10.
Crossref
Hao Qiu, Jingjing Li, Guangquan Chen, Tianyi Cao, Jing Li, Xing Li & Rongliang Qiu. (2023) Penetration of micro/nanoplastics into biological barriers in organisms and associated health effects. Chinese Science Bulletin.
Crossref
Jasreen Kaur, Egle Kelpsiene, Govind Gupta, Illia Dobryden, Tommy Cedervall & Bengt Fadeel. (2023) Label-free detection of polystyrene nanoparticles in Daphnia magna using Raman confocal mapping . Nanoscale Advances 5:13, pages 3453-3462.
Crossref
Mónica Torres-Ruiz, Mercedes de Alba González, Mónica Morales, Raquel Martin-Folgar, Mª. Carmen González, Ana I. Cañas-Portilla & Antonio De la Vieja. (2023) Neurotoxicity and endocrine disruption caused by polystyrene nanoparticles in zebrafish embryo. Science of The Total Environment 874, pages 162406.
Crossref
Andi Alijagic, Alexander Hedbrant, Alexander Persson, Maria Larsson, Magnus Engwall & Eva Särndahl. (2023) NLRP3 inflammasome as a sensor of micro- and nanoplastics immunotoxicity. Frontiers in Immunology 14.
Crossref
Jun Hyung Park, Seungwoo Hong, Ok-Hyeon Kim, Chul-Hong Kim, Jinho Kim, Jung-Woong Kim, Sungguan Hong & Hyun Jung Lee. (2023) Polypropylene microplastics promote metastatic features in human breast cancer. Scientific Reports 13:1.
Crossref
Zhimin Xu, Yuxue Zhang, Zhihao Xu, Yuming Zhong, Lei Wang, Chunguang Liu, Ailing Chen, Shanyu Jiang, Weimin Sun, Guohui Yu, Yanling Li, Chengzhang Li, Yifan Wang, Renqiang Yu & Le Zhang. (2023) Dysregulation of gut health in zebrafish by differentially charged nanoplastic exposure: an integrated analysis of histopathology, immunology, and microbial informatics. Environmental Science: Nano 10:3, pages 933-947.
Crossref
Elisabeth S. Gruber, Vanessa Stadlbauer, Verena Pichler, Katharina Resch-Fauster, Andrea Todorovic, Thomas C. Meisel, Sibylle Trawoeger, Oldamur Hollóczki, Suzanne D. Turner, Wolfgang Wadsak, A. Dick Vethaak & Lukas Kenner. (2022) To Waste or Not to Waste: Questioning Potential Health Risks of Micro- and Nanoplastics with a Focus on Their Ingestion and Potential Carcinogenicity. Exposure and Health 15:1, pages 33-51.
Crossref
Chelsea M. Cary, Glen M. DeLoid, Zhenning Yang, Dimitrios Bitounis, Marianne Polunas, Michael J. Goedken, Brian Buckley, Byron Cheatham, Phoebe A. Stapleton & Philip Demokritou. (2023) Ingested Polystyrene Nanospheres Translocate to Placenta and Fetal Tissues in Pregnant Rats: Potential Health Implications. Nanomaterials 13:4, pages 720.
Crossref
Shoumi Haldar, Yuvashree Muralidaran, Diana Míguez, Sikandar I. Mulla & Prabhakar Mishra. (2023) Eco-toxicity of nano-plastics and its implication on human metabolism: Current and future perspective. Science of The Total Environment 861, pages 160571.
Crossref
Abdullah Al Mamun, Tofan Agung Eka Prasetya, Indiah Ratna Dewi & Monsur Ahmad. (2023) Microplastics in human food chains: Food becoming a threat to health safety. Science of The Total Environment 858, pages 159834.
Crossref
Mathias Busch, Hugo Brouwer, Germaine Aalderink, Gerrit Bredeck, Angela A. M. Kämpfer, Roel P. F. Schins & Hans Bouwmeester. (2023) Investigating nanoplastics toxicity using advanced stem cell-based intestinal and lung in vitro models. Frontiers in Toxicology 5.
Crossref
Khaled Ziani, Corina-Bianca Ioniță-Mîndrican, Magdalena Mititelu, Sorinel Marius Neacșu, Carolina Negrei, Elena Moroșan, Doina Drăgănescu & Olivia-Teodora Preda. (2023) Microplastics: A Real Global Threat for Environment and Food Safety: A State of the Art Review. Nutrients 15:3, pages 617.
Crossref
Meng Yang & Wen-Xiong Wang. (2023) Recognition and movement of polystyrene nanoplastics in fish cells. Environmental Pollution 316, pages 120627.
Crossref
Yanping Cheng, Sheng Yang, Lihong Yin, Yuepu Pu & Geyu Liang. (2023) Recent consequences of micro-nanaoplastics (MNPLs) in subcellular/molecular environmental pollution toxicity on human and animals. Ecotoxicology and Environmental Safety 249, pages 114385.
Crossref
Guanglong Chen, Yizheng Li & Jun Wang. 2023. Airborne Microplastics: Analysis, Fate And Human Health Effects. Airborne Microplastics: Analysis, Fate And Human Health Effects 185 223 .
Hugo Brouwer, Femke L.N. Van Oijen & Hans Bouwmeester. 2023. Present Knowledge in Food Safety. Present Knowledge in Food Safety 590 605 .
Yolanda Prado, Cristobal Aravena, Diego Aravena, Felipe Eltit, Sebastian Gatica, Claudia A. Riedel & Felipe Simon. 2023. Advances in Molecular Pathology. Advances in Molecular Pathology 101 127 .
Maxi B. Paul, Christoph Fahrenson, Lucas Givelet, Tim Herrmann, Katrin Loeschner, Linda Böhmert, Andreas F. Thünemann, Albert Braeuning & Holger Sieg. (2022) Beyond microplastics - investigation on health impacts of submicron and nanoplastic particles after oral uptake in vitro. Microplastics and Nanoplastics 2:1.
Crossref
Ruud Peters, Nadine de Jong, Laura de Haan, Stephanie Wright & Hans Bouwmeester. (2022) Release and intestinal translocation of chemicals associated with microplastics in an in vitro human gastrointestinal digestion model. Microplastics and Nanoplastics 2:1.
Crossref
Julie R. Peller, Stephen P. Mezyk, Sarah Shidler, Joe Castleman, Scott Kaiser, Richard F. Faulkner, Corey D. Pilgrim, Antigone Wilson, Sydney Martens & Gregory P. Horne. (2022) Facile nanoplastics formation from macro and microplastics in aqueous media. Environmental Pollution 313, pages 120171.
Crossref
Nenad Joksimovic, Dragica Selakovic, Nemanja Jovicic, Nenad Jankovic, Periyakaruppan Pradeepkumar, Aziz Eftekhari & Gvozden Rosic. (2022) Nanoplastics as an Invisible Threat to Humans and the Environment. Journal of Nanomaterials 2022, pages 1-15.
Crossref
Wenjie Yang, Nahar Jannatun, Yanqiao Zeng, Tinghao Liu, Guofang Zhang, Chunying Chen & Yang Li. (2022) Impacts of microplastics on immunity. Frontiers in Toxicology 4.
Crossref
Jacek Baj, James Curtis Dring, Marcin Czeczelewski, Paweł Kozyra, Alicja Forma, Jolanta Flieger, Beata Kowalska, Grzegorz Buszewicz & Grzegorz Teresiński. (2022) Derivatives of Plastics as Potential Carcinogenic Factors: The Current State of Knowledge. Cancers 14:19, pages 4637.
Crossref
Glen M. DeLoid, Xiaoqiong Cao, Roxana Coreas, Dimitrios Bitounis, Dilpreet Singh, Wenwan Zhong & Philip Demokritou. (2022) Incineration-Generated Polyethylene Micro-Nanoplastics Increase Triglyceride Lipolysis and Absorption in an In Vitro Small Intestinal Epithelium Model . Environmental Science & Technology 56:17, pages 12288-12297.
Crossref
Flavia Carton & Manuela Malatesta. (2022) In Vitro Models of Biological Barriers for Nanomedical Research. International Journal of Molecular Sciences 23:16, pages 8910.
Crossref
Sai Archana Krovi, Maria M. Moreno Caffaro, Shyam Aravamudhan, Ninell P. Mortensen & Leah M. Johnson. (2022) Fabrication of Nylon-6 and Nylon-11 Nanoplastics and Evaluation in Mammalian Cells. Nanomaterials 12:15, pages 2699.
Crossref
Diqi Yang, Jiandi Zhu, Xiaoshu Zhou, Di Pan, Sha Nan, Ruiling Yin, Qianghui Lei, Ning Ma, Hongmei Zhu, Jianguo Chen, Li Han, Mingxing Ding & Yi Ding. (2022) Polystyrene micro- and nano-particle coexposure injures fetal thalamus by inducing ROS-mediated cell apoptosis. Environment International 166, pages 107362.
Crossref
Laura Schröter & Natascia Ventura. (2022) Nanoplastic Toxicity: Insights and Challenges from Experimental Model Systems. Small 18:31.
Crossref
María-Carmen López de las Hazas, Hatim Boughanem & Alberto Dávalos. (2022) Untoward Effects of Micro- and Nanoplastics: An Expert Review of Their Biological Impact and Epigenetic Effects. Advances in Nutrition 13:4, pages 1310-1323.
Crossref
Chenxu Yu, Paul Takhistov, Evangelyn Alocilja, Jose Reyes de Corcuera, Margaret W. Frey, Carmen L. Gomes, Yu J. Mao, Eric S. McLamore, Mengshi Lin, Olga V. Tsyusko, Tzuen-Rong J. Tzeng, Jeong-Yeol Yoon & Anhong Zhou. (2022) Bioanalytical approaches for the detection, characterization, and risk assessment of micro/nanoplastics in agriculture and food systems. Analytical and Bioanalytical Chemistry 414:16, pages 4591-4612.
Crossref
Boxuan Liang, Yuji Huang, Yizhou Zhong, Zhiming Li, Rongyi Ye, Bo Wang, Bingli Zhang, Hao Meng, Xi Lin, Jiaxin Du, Manjiang Hu, Qinghong Wu, Haixia Sui, Xingfen Yang & Zhenlie Huang. (2022) Brain single-nucleus transcriptomics highlights that polystyrene nanoplastics potentially induce Parkinson’s disease-like neurodegeneration by causing energy metabolism disorders in mice. Journal of Hazardous Materials 430, pages 128459.
Crossref
Pei Cao, Zhi Ping Xu & Li Li. (2022) Tailoring functional nanoparticles for oral vaccine delivery: Recent advances and future perspectives. Composites Part B: Engineering 236, pages 109826.
Crossref
Lia N. Corbett & Linda A. Amaral‐Zettler. 2022. Plastics and the Ocean. Plastics and the Ocean 389 428 .
Ludivine Delon, Rachel J. Gibson, Clive A Prestidge & Benjamin Thierry. (2022) Mechanisms of uptake and transport of particulate formulations in the small intestine. Journal of Controlled Release 343, pages 584-599.
Crossref
Fei Dang, Qingyu Wang, Yingnan Huang, Yujun Wang & Baoshan Xing. (2022) Key knowledge gaps for One Health approach to mitigate nanoplastic risks. Eco-Environment & Health 1:1, pages 11-22.
Crossref
Xiaohan Tong, Boqing Li, Jing Li, Lan Li, Ruiqing Zhang, Yunqiu Du & Ying Zhang. (2022) Polyethylene microplastics cooperate with Helicobacter pylori to promote gastric injury and inflammation in mice. Chemosphere 288, pages 132579.
Crossref
Todd Gouin, Robert Ellis-Hutchings, Leah M. Thornton Hampton, Christine L. Lemieux & Stephanie L. Wright. (2022) Screening and prioritization of nano- and microplastic particle toxicity studies for evaluating human health risks – development and application of a toxicity study assessment tool. Microplastics and Nanoplastics 2:1.
Crossref
Haihong Zhang, Haodong Cheng, Yudi Wang, Zhenghua Duan, Wenjie Cui, Yansong Shi & Li Qin. (2022) Influence of Functional Group Modification on the Toxicity of Nanoplastics. Frontiers in Marine Science 8.
Crossref
Gerrit Bredeck, Blanka Halamoda-Kenzaoui, Alessia Bogni, Dorelia Lipsa & Susanne Bremer-Hoffmann. (2022) Tiered testing of micro- and nanoplastics using intestinal in vitro models to support hazard assessments. Environment International 158, pages 106921.
Crossref
Seta Noventa, Matthew S. P. Boyles, Andreas Seifert, Simone Belluco, Aracaeli Sánchez Jiménez, Helinor J. Johnston, Lang Tran, Teresa F. Fernandes, Lapo Mughini-Gras, Massimiliano Orsini, Fabiana Corami, Kepa Castro, Franco Mutinelli, Massimo Boldrin, Victor Puntes, Mahshid Sotoudeh, Giulia Mascarello, Barbara Tiozzo, Polly McLean, Francesca Ronchi, Andy M. Booth, Albert A. Koelmans & Carmen Losasso. (2021) Paradigms to assess the human health risks of nano- and microplastics. Microplastics and Nanoplastics 1:1.
Crossref
Boxuan Liang, Yizhou Zhong, Yuji Huang, Xi Lin, Jun Liu, Li Lin, Manjiang Hu, Junying Jiang, Mingzhu Dai, Bo Wang, Bingli Zhang, Hao Meng, Jesse Justin J. Lelaka, Haixia Sui, Xingfen Yang & Zhenlie Huang. (2021) Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis. Particle and Fibre Toxicology 18:1.
Crossref
Glen M. DeLoid, Xiaoqiong Cao, Dimitrios Bitounis, Dilpreet Singh, Paula Montero Llopis, Brian Buckley & Philip Demokritou. (2021) Toxicity, uptake, and nuclear translocation of ingested micro-nanoplastics in an in vitro model of the small intestinal epithelium. Food and Chemical Toxicology 158, pages 112609.
Crossref
Monica Torres-Ruiz, Antonio De la Vieja, Mercedes de Alba Gonzalez, Marta Esteban Lopez, Argelia Castaño Calvo & Ana Isabel Cañas Portilla. (2021) Toxicity of nanoplastics for zebrafish embryos, what we know and where to go next. Science of The Total Environment 797, pages 149125.
Crossref
Masahito Ban, Ryouta Shimoda & Jing Chen. (2021) Investigation of nanoplastic cytotoxicity using SH-SY5Y human neuroblastoma cells and polystyrene nanoparticles. Toxicology in Vitro 76, pages 105225.
Crossref
Concetta Pironti, Maria Ricciardi, Oriana Motta, Ylenia Miele, Antonio Proto & Luigi Montano. (2021) Microplastics in the Environment: Intake through the Food Web, Human Exposure and Toxicological Effects. Toxics 9:9, pages 224.
Crossref
Sara Matthews, Lei Mai, Chang-Bum Jeong, Jae-Seong Lee, Eddy Y. Zeng & Elvis Genbo Xu. (2021) Key mechanisms of micro- and nanoplastic (MNP) toxicity across taxonomic groups. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 247, pages 109056.
Crossref
Kurunthachalam Kannan & Krishnamoorthi Vimalkumar. (2021) A Review of Human Exposure to Microplastics and Insights Into Microplastics as Obesogens. Frontiers in Endocrinology 12.
Crossref
Olga Hartwig, Maryam A. Shetab Boushehri, Karim S. Shalaby, Brigitta Loretz, Alf Lamprecht & Claus-Michael Lehr. (2021) Drug delivery to the inflamed intestinal mucosa – targeting technologies and human cell culture models for better therapies of IBD. Advanced Drug Delivery Reviews 175, pages 113828.
Crossref
Giuseppa Visalli, Alessio Facciolà, Marianna Pruiti Ciarello, Giuseppe De Marco, Maria Maisano & Angela Di Pietro. (2021) Acute and Sub-Chronic Effects of Microplastics (3 and 10 µm) on the Human Intestinal Cells HT-29. International Journal of Environmental Research and Public Health 18:11, pages 5833.
Crossref
Yvonne Kohl, Michelle Hesler, Roland Drexel, Lukas Kovar, Stephan Dähnhardt-Pfeiffer, Dominik Selzer, Sylvia Wagner, Thorsten Lehr, Hagen von Briesen & Florian Meier. (2021) Influence of Physicochemical Characteristics and Stability of Gold and Silver Nanoparticles on Biological Effects and Translocation across an Intestinal Barrier—A Case Study from In Vitro to In Silico. Nanomaterials 11:6, pages 1358.
Crossref
Sun Jo Kim, Nguyen Phuoc Long, Cheol Woon Jung, Nguyen Hoang Anh, Jung Eun Min, Hyung Min Kim & Sung Won Kwon. (2021) Exposure to nano-polystyrene induces metabolic alteration in lipid homeostasis in Caco-2. Environmental Science: Nano 8:5, pages 1408-1424.
Crossref
Lixin Wang, Yingxue Wang, Man Xu, Juan Ma, Shuping Zhang, Sijin Liu, Ke Wang, Huifang Tian & Jiansheng Cui. (2021) Enhanced hepatic cytotoxicity of chemically transformed polystyrene microplastics by simulated gastric fluid. Journal of Hazardous Materials 410, pages 124536.
Crossref
Omar A. Vázquez & Md Saydur Rahman. (2021) An ecotoxicological approach to microplastics on terrestrial and aquatic organisms: A systematic review in assessment, monitoring and biological impact. Environmental Toxicology and Pharmacology 84, pages 103615.
Crossref
Tianxu Zhang, Guanyin Zhu, Boyao Lu, Zhiyong Qian & Qiang Peng. (2020) Protein corona formed in the gastrointestinal tract and its impacts on oral delivery of nanoparticles. Medicinal Research Reviews 41:3, pages 1835-1850.
Crossref
Angela A. M. Kämpfer, Mathias Busch, Veronika Büttner, Gerrit Bredeck, Burkhard Stahlmecke, Bryan Hellack, Isabelle Masson, Adriana Sofranko, Catrin Albrecht & Roel P. F. Schins. (2021) Model Complexity as Determining Factor for In Vitro Nanosafety Studies: Effects of Silver and Titanium Dioxide Nanomaterials in Intestinal Models. Small 17:15.
Crossref
Robert Molenaar, Swarupa Chatterjee, Bjorn Kamphuis, Ine M. J. Segers-Nolten, Mireille M. A. E. Claessens & Christian Blum. (2021) Nanoplastic sizes and numbers: quantification by single particle tracking. Environmental Science: Nano 8:3, pages 723-730.
Crossref
Maxine Swee-Li Yee, Ling-Wei Hii, Chin King Looi, Wei-Meng Lim, Shew-Fung Wong, Yih-Yih Kok, Boon-Keat Tan, Chiew-Yen Wong & Chee-Onn Leong. (2021) Impact of Microplastics and Nanoplastics on Human Health. Nanomaterials 11:2, pages 496.
Crossref
Amrita Banerjee & Weilin L. Shelver. (2021) Micro- and nanoplastic induced cellular toxicity in mammals: A review. Science of The Total Environment 755, pages 142518.
Crossref
Ninell P. Mortensen, Timothy R. Fennell & Leah M. Johnson. (2021) Unintended human ingestion of nanoplastics and small microplastics through drinking water, beverages, and food sources. NanoImpact 21, pages 100302.
Crossref
József Lehel & Sadhbh Murphy. 2021. Reviews of Environmental Contamination and Toxicology Volume 259. Reviews of Environmental Contamination and Toxicology Volume 259 1 49 .
Maxi B. Paul, Valerie Stock, Julia Cara-Carmona, Elisa Lisicki, Sofiya Shopova, Valérie Fessard, Albert Braeuning, Holger Sieg & Linda Böhmert. (2020) Micro- and nanoplastics – current state of knowledge with the focus on oral uptake and toxicity. Nanoscale Advances 2:10, pages 4350-4367.
Crossref
Angela A. M. Kämpfer, Mathias Busch & Roel P. F. Schins. (2020) Advanced In Vitro Testing Strategies and Models of the Intestine for Nanosafety Research . Chemical Research in Toxicology 33:5, pages 1163-1178.
Crossref
Rhodesherdeline Limage, Elad Tako, Nikolai Kolba, Zhongyuan Guo, Alba García‐Rodríguez, Cláudia N. H. Marques & Gretchen J. Mahler. (2020) TiO 2 Nanoparticles and Commensal Bacteria Alter Mucus Layer Thickness and Composition in a Gastrointestinal Tract Model . Small 16:21.
Crossref
Cheryl Yong, Suresh Valiyaveettil & Bor Tang. (2020) Toxicity of Microplastics and Nanoplastics in Mammalian Systems. International Journal of Environmental Research and Public Health 17:5, pages 1509.
Crossref
Frederikke Emilie Heddagaard & Peter Møller. (2020) Hazard assessment of small-size plastic particles: is the conceptual framework of particle toxicology useful?. Food and Chemical Toxicology 136, pages 111106.
Crossref
Valerie Stock, Linda Böhmert, Merve Hilal Dönmez, Alfonso Lampen & Holger Sieg. (2020) An inverse cell culture model for floating plastic particles. Analytical Biochemistry 591, pages 113545.
Crossref
Constanza Cortés, Josefa Domenech, Marcela Salazar, Susana Pastor, Ricard Marcos & Alba Hernández. (2020) Nanoplastics as a potential environmental health factor: effects of polystyrene nanoparticles on human intestinal epithelial Caco-2 cells. Environmental Science: Nano 7:1, pages 272-285.
Crossref
Ninell P. Mortensen, Maria Moreno Caffaro, Purvi R. Patel, Md Jamal Uddin, Shyam Aravamudhan, Susan J. Sumner & Timothy R. Fennell. (2020) Investigation of twenty metal, metal oxide, and metal sulfide nanoparticles' impact on differentiated Caco-2 monolayer integrity. NanoImpact 17, pages 100212.
Crossref
Wai-Houng Chou, Tessa Lühmann, Lorenz Meinel & Javier Octavio Morales. 2020. Nanopharmaceuticals: Principles and Applications Vol. 3. Nanopharmaceuticals: Principles and Applications Vol. 3 271 315 .
Victor C. Ude, David M. Brown, Vicki Stone & Helinor J. Johnston. (2019) Using 3D gastrointestinal tract in vitro models with microfold cells and mucus secreting ability to assess the hazard of copper oxide nanomaterials. Journal of Nanobiotechnology 17:1.
Crossref
Michelle Hesler, Leonie Aengenheister, Bernhard Ellinger, Roland Drexel, Susanne Straskraba, Carsten Jost, Sylvia Wagner, Florian Meier, Hagen von Briesen, Claudia Büchel, Peter Wick, Tina Buerki-Thurnherr & Yvonne Kohl. (2019) Multi-endpoint toxicological assessment of polystyrene nano- and microparticles in different biological models in vitro. Toxicology in Vitro 61, pages 104610.
Crossref
Nicholas G. Lamson, Adrian Berger, Katherine C. Fein & Kathryn A. Whitehead. (2019) Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability. Nature Biomedical Engineering 4:1, pages 84-96.
Crossref
Amber Nagy & Nicholas L Robbins. (2019) The hurdles of nanotoxicity in transplant nanomedicine. Nanomedicine 14:20, pages 2749-2762.
Crossref
Maocai Shen, Yaxin Zhang, Yuan Zhu, Biao Song, Guangming Zeng, Duofei Hu, Xiaofeng Wen & Xiaoya Ren. (2019) Recent advances in toxicological research of nanoplastics in the environment: A review. Environmental Pollution 252, pages 511-521.
Crossref
Ana G. Rodríguez-Hernández, J. Alejandro Muñoz-Tabares, J. Cristobal Aguilar-Guzmán & Rafael Vazquez-Duhalt. (2019) A novel and simple method for polyethylene terephthalate (PET) nanoparticle production. Environmental Science: Nano 6:7, pages 2031-2036.
Crossref
Mingzhu Zhou, Xiaoqian Ge, Da-Ming Ke, Huan Tang, Jun-Zheng Zhang, Matteo Calvaresi, Bin Gao, Lining Sun, Qianqian Su & Haifang Wang. (2019) The Bioavailability, Biodistribution, and Toxic Effects of Silica-Coated Upconversion Nanoparticles in vivo. Frontiers in Chemistry 7.
Crossref
Victor C. Ude, David M. Brown, Krystyna Maciaszek, Vicki Stone & Helinor J. Johnston. (2019) Comparing the sensitivity of different intestinal Caco-2 in vitro monocultures and co-cultures to amorphous silicon dioxide nanomaterials and the clay montmorillonite. NanoImpact 15, pages 100165.
Crossref
Roman Lehner, Christoph Weder, Alke Petri-Fink & Barbara Rothen-Rutishauser. (2019) Emergence of Nanoplastic in the Environment and Possible Impact on Human Health. Environmental Science & Technology 53:4, pages 1748-1765.
Crossref
Alina Strugari, Miruna Stan, Sami Gharbia, Anca Hermenean & Anca Dinischiotu. (2018) Characterization of Nanoparticle Intestinal Transport Using an In Vitro Co-Culture Model. Nanomaterials 9:1, pages 5.
Crossref
Ashraf Abdelkhaliq, Meike van der Zande, Ans Punt, Richard Helsdingen, Sjef Boeren, Jacques J. M. Vervoort, Ivonne M. C. M. Rietjens & Hans Bouwmeester. (2018) Impact of nanoparticle surface functionalization on the protein corona and cellular adhesion, uptake and transport. Journal of Nanobiotechnology 16:1.
Crossref
Joël Bourquin, Ana Milosevic, Daniel Hauser, Roman Lehner, Fabian Blank, Alke Petri‐Fink & Barbara Rothen‐Rutishauser. (2018) Biodistribution, Clearance, and Long‐Term Fate of Clinically Relevant Nanomaterials. Advanced Materials 30:19.
Crossref
Jonas Reinholz, Christopher Diesler, Susanne Schöttler, Maria Kokkinopoulou, Sandra Ritz, Katharina Landfester & Volker Mailänder. (2018) Protein machineries defining pathways of nanocarrier exocytosis and transcytosis. Acta Biomaterialia 71, pages 432-443.
Crossref
Valentina Francia, Aldy Aliyandi & Anna Salvati. (2018) Effect of the development of a cell barrier on nanoparticle uptake in endothelial cells. Nanoscale 10:35, pages 16645-16656.
Crossref
Roman Lehner, Alke Petri-Fink & Barbara Rothen-Rutishauser. 2018. Proceedings of the International Conference on Microplastic Pollution in the Mediterranean Sea. Proceedings of the International Conference on Microplastic Pollution in the Mediterranean Sea 167 170 .
Victor C. Ude, David M. Brown, Luca Viale, Nilesh Kanase, Vicki Stone & Helinor J. Johnston. (2017) Impact of copper oxide nanomaterials on differentiated and undifferentiated Caco-2 intestinal epithelial cells; assessment of cytotoxicity, barrier integrity, cytokine production and nanomaterial penetration. Particle and Fibre Toxicology 14:1.
Crossref
Dajana Lichtenstein, Thomas Meyer, Linda Böhmert, Sabine Juling, Christoph Fahrenson, Sören Selve, Andreas Thünemann, Jan Meijer, Irina Estrela-Lopis, Albert Braeuning & Alfonso Lampen. (2017) Dosimetric Quantification of Coating-Related Uptake of Silver Nanoparticles. Langmuir 33:45, pages 13087-13097.
Crossref
Dong Ye, Mattia Bramini, Delyan R Hristov, Sha Wan, Anna Salvati, Christoffer Åberg & Kenneth A Dawson. (2017) Low uptake of silica nanoparticles in Caco-2 intestinal epithelial barriers. Beilstein Journal of Nanotechnology 8, pages 1396-1406.
Crossref
Joan Cabellos, Camilla Delpivo, Elisabet Fernández-Rosas, Socorro Vázquez-Campos & Gemma Janer. (2017) Contribution of M-cells and other experimental variables in the translocation of TiO2 nanoparticles across in vitro intestinal models. NanoImpact 5, pages 51-60.
Crossref
Mark A. Jepson & Hans Bouwmeester. 2017. Adverse Effects of Engineered Nanomaterials. Adverse Effects of Engineered Nanomaterials 381 396 .
Silvia Gabriella Ciappellano, Erik Tedesco, Marco Venturini & Federico Benetti. (2016) In vitro toxicity assessment of oral nanocarriers. Advanced Drug Delivery Reviews 106, pages 381-401.
Crossref
Leonardo Ricotti, Giulia Gori, Daniele Cei, Joana Costa, Giovanni Signore & Arti Ahluwalia. (2016) Polymeric Microporous Nanofilms as Smart Platforms for <italic>in Vitro</italic> Assessment of Nanoparticle Translocation and Caco-2 Cell Culture. IEEE Transactions on NanoBioscience 15:7, pages 689-696.
Crossref
Eleonore Fröhlich & Eva Roblegg. (2016) Oral uptake of nanoparticles: human relevance and the role of in vitro systems. Archives of Toxicology 90:10, pages 2297-2314.
Crossref
. (2016) Presence of microplastics and nanoplastics in food, with particular focus on seafood. EFSA Journal 14:6.
Crossref
Desirè Di Silvio, Neil Rigby, Balazs Bajka, Alan Mackie & Francesca Baldelli Bombelli. (2016) Effect of protein corona magnetite nanoparticles derived from bread in vitro digestion on Caco-2 cells morphology and uptake. The International Journal of Biochemistry & Cell Biology 75, pages 212-222.
Crossref
Carina Muoth, Leonie Aengenheister, Melanie Kucki, Peter Wick & Tina Buerki-Thurnherr. (2016) Nanoparticle transport across the placental barrier: pushing the field forward!. Nanomedicine 11:8, pages 941-957.
Crossref
Federico Benetti, Christian Micheletti & Laura Manodori. 2016. Nutraceuticals. Nutraceuticals 183 230 .
Hans Bouwmeester, Peter C. H. Hollman & Ruud J. B. Peters. (2015) Potential Health Impact of Environmentally Released Micro- and Nanoplastics in the Human Food Production Chain: Experiences from Nanotoxicology. Environmental Science & Technology 49:15, pages 8932-8947.
Crossref
Seon Ae Hwangbo, In Young Kim, Gwansuk Kang, Jaeseok Kim & Tae Geol Lee. (2022) Preparation of Environmentally Comparable Fragmented Polyethylene Nanoplastics for Toxicity Evaluation. SSRN Electronic Journal.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.