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Nanotoxicology Volume 9, 2015 - Issue 5
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Original Article

Intratracheal exposure to multi-walled carbon nanotubes induces a nonalcoholic steatohepatitis-like phenotype in C57BL/6J mice

Ji-Eun KimLaboratory of Toxicology, BK21 PLUS Program for Creative Veterinary Science Research, Research Institute for Veterinary Science and College of Veterinary Medicine, Seoul National University, Seoul, Korea, ;Graduate School of Convergence Science and Technology, Seoul National University, Suwon, Korea,
,
Somin LeeLaboratory of Toxicology, BK21 PLUS Program for Creative Veterinary Science Research, Research Institute for Veterinary Science and College of Veterinary Medicine, Seoul National University, Seoul, Korea, ;Graduate Group of Tumor Biology, Seoul National University, Seoul, Korea,
,
Ah Young LeeLaboratory of Toxicology, BK21 PLUS Program for Creative Veterinary Science Research, Research Institute for Veterinary Science and College of Veterinary Medicine, Seoul National University, Seoul, Korea,
,
Hwi Won SeoLaboratory of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Korea, and
,
Chanhee ChaeLaboratory of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Korea, and
&
Myung-Haing ChoLaboratory of Toxicology, BK21 PLUS Program for Creative Veterinary Science Research, Research Institute for Veterinary Science and College of Veterinary Medicine, Seoul National University, Seoul, Korea, ;Graduate School of Convergence Science and Technology, Seoul National University, Suwon, Korea, ;Graduate Group of Tumor Biology, Seoul National University, Seoul, Korea, ;Advanced Institute of Convergence Technology, Seoul National University, Suwon, KoreaCorrespondence[email protected]
Pages 613-623 | Received 03 Feb 2014, Accepted 04 Sep 2014, Published online: 29 Sep 2014

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Hailong Hu, Qian Guo, Xingpei Fan, Xiangjuan Wei, Daqian Yang, Boya Zhang, Jing Liu, Qiong Wu, Yuri Oh, Yujie Feng, Kun Chen, Liping Hou & Ning Gu. (2020) Molecular mechanisms underlying zinc oxide nanoparticle induced insulin resistance in mice. Nanotoxicology 14:1, pages 59-76.
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Jie Dong & Qiang Ma. (2019) Integration of inflammation, fibrosis, and cancer induced by carbon nanotubes. Nanotoxicology 13:9, pages 1244-1274.
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Articles from other publishers (10)

Pius Joseph. 2023. Impact of Engineered Nanomaterials in Genomics and Epigenomics. Impact of Engineered Nanomaterials in Genomics and Epigenomics 187 215 .
Seyed Mohammad Hosseini, Javad Mohammadnejad, Roqya Najafi-Taher, Zahra Beiram Zadeh, Mohammad Tanhaei & Seeram Ramakrishna. (2023) Multifunctional Carbon-Based Nanoparticles: Theranostic Applications in Cancer Therapy and Diagnosis. ACS Applied Bio Materials 6:4, pages 1323-1338.
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Ji-Eun Kim & Myung-Haing Cho. (2023) Effects of Multiwall Carbon Nanotubes on Premature Kidney Aging: Biochemical and Histological Analysis. Toxics 11:4, pages 373.
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Marta Witkowska, Ewa Florek & Radosław Mrówczyński. (2022) Assessment of Pristine Carbon Nanotubes Toxicity in Rodent Models. International Journal of Molecular Sciences 23:23, pages 15343.
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Ting Sun, Yiyuan Kang, Jia Liu, Yanli Zhang, Lingling Ou, Xiangning Liu, Renfa Lai & Longquan Shao. (2021) Nanomaterials and hepatic disease: toxicokinetics, disease types, intrinsic mechanisms, liver susceptibility, and influencing factors. Journal of Nanobiotechnology 19:1.
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Enqin Liu, Xinghui Wang, Xidong Li, Ping Tian, Hao Xu, Zenglian Li & Likun Wang. (2020) Co-exposure to multi-walled carbon nanotube and lead ions aggravates hepatotoxicity of nonalcoholic fatty liver via inhibiting AMPK/PPARγ pathway. Aging 12:14, pages 14189-14204.
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Kristina B. Knudsen, Trine Berthing, Petra Jackson, Sarah S. Poulsen, Alicja Mortensen, Nicklas R. Jacobsen, Vidar Skaug, Józef Szarek, Karin S. Hougaard, Henrik Wolff, Håkan Wallin & Ulla Vogel. (2019) Physicochemical predictors of Multi-Walled Carbon Nanotube-induced pulmonary histopathology and toxicity one year after pulmonary deposition of 11 different Multi-Walled Carbon Nanotubes in mice. Basic & Clinical Pharmacology & Toxicology 124:2, pages 211-227.
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Chunxue Zhao, Yiwei Zhou, Liangliang Liu, Jimin Long, Hongwen Liu, Juan Li & Yi Cao. (2018) Lipid accumulation in multi-walled carbon nanotube-exposed HepG2 cells: Possible role of lipophagy pathway. Food and Chemical Toxicology 121, pages 65-71.
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Sarah S. Poulsen, Kristina B. Knudsen, Petra Jackson, Ingrid E. K. Weydahl, Anne T. Saber, Håkan Wallin & Ulla Vogel. (2017) Multi-walled carbon nanotube-physicochemical properties predict the systemic acute phase response following pulmonary exposure in mice. PLOS ONE 12:4, pages e0174167.
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Sarah S. Poulsen, Anne T. Saber, Alicja Mortensen, Józef Szarek, Dongmei Wu, Andrew Williams, Ole Andersen, Nicklas R. Jacobsen, Carole L. Yauk, Håkan Wallin, Sabina Halappanavar & Ulla Vogel. (2015) Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease. Toxicology and Applied Pharmacology 283:3, pages 210-222.
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