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Original Article

Effect of Instability on Experimental Fracture Healing

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Pages 521-526 | Accepted 26 Oct 1981, Published online: 08 Jul 2009

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Read on this site (15)

Jukka Kettunen, Antero Mäkelä, Hannu Miettinen, Timo Nevalainen, Mika Heikkilä, Pertti Törmälä & Pentti Rokkanen. (1999) Fixation of distal femoral osteotomy with an intramedullary rod: Early failure of carbon fibre composite implant in rabbits. Journal of Biomaterials Science, Polymer Edition 10:7, pages 715-728.
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Jukka Kettunen, Antero Mäkelä, Hannu Miettinen, Timo Nevalainen, Mika Heikkilä, Pertti Törmälä & Pentti Rokkanen. (1999) Fixation of femoral shaft osteotomy with an intramedullary composite rod: An experimental study on dogs with a two-year follow-up. Journal of Biomaterials Science, Polymer Edition 10:1, pages 33-45.
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Oliver Grundnes, Stein Erik Utvag & Olav Reikeras. (1994) Effects of graded reaming on fracture healing: Blood flow and healing studied in rat femurs. Acta Orthopaedica Scandinavica 65:1, pages 32-36.
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Martinus Bråten, Asbjørn Nordby & Terje Terjesen. (1993) Bone density and geometry after locked intramedullary nailing: Computed tomography of 8 femoral fractures. Acta Orthopaedica Scandinavica 64:1, pages 79-81.
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Oliver Grundnes & Olav Reikerås. (1993) Effects of instability on bone healing: Femoral osteotomies studied in rats. Acta Orthopaedica Scandinavica 64:1, pages 55-58.
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Oliver Grundnes & Olav Reikerås. (1991) Mechanical effects of function on bone healing: Nonweight bearing and exercise in osteotomized rats. Acta Orthopaedica Scandinavica 62:2, pages 163-165.
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Otto Schnell Husby, Nils Roar Gjerdet & Anders O. Melster. (1989) Strain shielding 12 weeks after femoral reaming and nailing in rats. Acta Orthopaedica Scandinavica 60:3, pages 349-352.
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Anders Henricson, Anders Hulth & Olof Johnell. (1987) The cartilaginous fracture callus in rats. Acta Orthopaedica Scandinavica 58:3, pages 244-248.
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Andris Kreicbergs & Peter Köhler. (1987) Diaphyseal reconstruction by autoclaved bone: Reimplantation experiments in rabbits. Acta Orthopaedica Scandinavica 58:1, pages 61-65.
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Esko Kaartinen, Pekka Paavolainen, Teddy Holmström & Pär Slätis. (1985) Loss of bone strength after intramedullary nailing: Torsion tests of tibial osteotomies in rabbits. Acta Orthopaedica Scandinavica 56:6, pages 487-490.
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Anders O. Melster, Torbjørn Strand, Arne Skredderstuen, Lars B. Engesæter, Tor Steinar Raugstad & Antti Alho. (1984) Extra-articular stabilization of the knee a.m. Losee. Acta Orthopaedica Scandinavica 55:6, pages 640-642.
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Anders O. Mølster. (1984) Effects of rotational instability on healing of femoral osteotomies in the rat. Acta Orthopaedica Scandinavica 55:6, pages 632-636.
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Anders O. Mølster & Nils Roar Gjerdet. (1984) Effects of instability on fracture healing in the rat. Acta Orthopaedica Scandinavica 55:3, pages 342-346.
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Anders O. Molster, Nils R. Gjerdet, Antti Alho & Gisle Bang. (1983) Fracture Healing After Rigid Intramedullary Nailing in Rats. Acta Orthopaedica Scandinavica 54:3, pages 366-373.
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Kentaro Ito, Yu Mori, Masayuki Kamimura, Masashi Koguchi, Hiroaki Kurishima, Tomoki Koyama, Naoko Mori, Naoya Masahashi, Shuji Hanada, Eiji Itoi & Toshimi Aizawa. (2022) β-type TiNbSn Alloy Plates With Low Young Modulus Accelerates Osteosynthesis in Rabbit Tibiae. Clinical Orthopaedics & Related Research 480:9, pages 1817-1832.
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Daisuke Chiba, Norikazu Yamada, Yu Mori, Masamizu Oyama, Susumu Ohtsu, Yoshiyuki Kuwahara, Kazuyoshi Baba, Hidetatsu Tanaka, Toshimi Aizawa, Shuji Hanada & Eiji Itoi. (2021) Mid-term results of a new femoral prosthesis using Ti-Nb-Sn alloy with low Young’s modulus. BMC Musculoskeletal Disorders 22:1.
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Yu Mori, Hirokazu Fujisawa, Masayuki Kamimura, Atsushi Kogure, Hidetatsu Tanaka, Naoko Mori, Naoya Masahashi & Toshimi Aizawa. (2021) Acceleration of Fracture Healing in Mouse Tibiae Using Intramedullary Nails Composed of <i>β</i>-Type TiNbSn Alloy with Low Young’s Modulus. The Tohoku Journal of Experimental Medicine 255:2, pages 135-142.
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Atsushi Kogure, Yu Mori, Hidetatsu Tanaka, Masayuki Kamimura, Naoya Masahashi, Shuji Hanada & Eiji Itoi. (2019) Effects of elastic intramedullary nails composed of low Young's modulus Ti-Nb-Sn alloy on healing of tibial osteotomies in rabbits. Journal of Biomedical Materials Research Part B: Applied Biomaterials 107:3, pages 700-707.
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Hirokazu Fujisawa, Yu Mori, Atsushi Kogure, Hidetatsu Tanaka, Masayuki Kamimura, Naoya Masahashi, Shuji Hanada & Eiji Itoi. (2018) Effects of intramedullary nails composed of a new β-type Ti-Nb-Sn alloy with low Young's modulus on fracture healing in mouse tibiae. Journal of Biomedical Materials Research Part B: Applied Biomaterials 106:8, pages 2841-2848.
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Fernando Y. Zapata-Cornelio, Zhongmin Jin, David C. Barton, Alison C. Jones & Ruth K. Wilcox. (2018) A methodology for the generation and non-destructive characterisation of transverse fractures in long bones. Bone Reports 8, pages 221-228.
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Masaki UENO, Kentaro UCHIDA, Masashi TAKASO, Hiroaki MINEHARA, Kaori SUTO, Naonobu TAKAHIRA, Roland STECK, Michael A. SCHUETZ & Moritoshi ITOMAN. (2011) Distribution of Bone Marrow-Derived Cells in the Fracture Callus during Plate Fixation in a Green Fluorescent Protein-Chimeric Mouse Model. Experimental Animals 60:5, pages 455-462.
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Matthias Schoen, Robert Rotter, Simone Schattner, Thomas Mittlmeier, Lutz Claes, Brigitte Vollmar & Georg Gradl. (2007) Introduction of a new interlocked intramedullary nailing device for stabilization of critically sized femoral defects in the rat: A combined biomechanical and animal experimental study. Journal of Orthopaedic Research 26:2, pages 184-189.
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Sandra J. Shefelbine, Peter Augat, Lutz Claes & Alexander Beck. (2005) Intact fibula improves fracture healing in a rat tibia osteotomy model. Journal of Orthopaedic Research 23:2, pages 489-493.
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L Rasubala, H Yoshikawa, A.A.S Islam, K Nagata, T Iijima & M Ohishi. (2004) Comparison of the healing process in plated and non-plated fractures of the mandible in rats. British Journal of Oral and Maxillofacial Surgery 42:4, pages 315-322.
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Andy Petroianu, Renato Abranches Corsetti & Luiz Ronaldo Alberti. (2004) The effect of the presence of muscle tissue in a bone healing site. Revista do Hospital das Clínicas 59:4, pages 193-197.
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Chris K. Connolly, Gang Li, Jonathan R. Bunn, Moses Mushipe, Glenn R. Dickson & David R. Marsh. (2006) A reliable externally fixated murine femoral fracture model that accounts for variation in movement between animals. Journal of Orthopaedic Research 21:5, pages 843-849.
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A. Seitz, A.M. Uhrmacher & D. Damm. (1999) Case-based prediction in experimental medical studies. Artificial Intelligence in Medicine 15:3, pages 255-273.
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A. Probst, H. Jansen, A. Ladas & H. U. Spiegel. (2005) Callus formation and fixation rigidity: A fracture model in rats. Journal of Orthopaedic Research 17:2, pages 256-260.
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J. Sun, E. W. Abel & D. I. Rowley. (1998) Mechanical Performance of an Axially Mobile Plate for Fracture Fixation. The Journal of Trauma: Injury, Infection, and Critical Care 44:2, pages 368-371.
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J. Viljanen, J. Kinnunen, S. Bondestam & P. Rokkanen. (1998) Intramedullary fixation of distal femoral diaphyseal osteotomies with absorbable self-reinforced poly-L-lactide and metallic intramedullary rods assessed by plain radiographs, quantitative computed tomography, and magnetic resonance imaging: An experimental study in rabbits. Journal of Biomedical Materials Research 39:2, pages 222-228.
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Georg N. Duda, Helmut Kirchner, Hans-Joachim Wilke & Lutz Claes. (1997) A method to determine the 3-D stiffness of fracture fixation devices and its application to predict inter-fragmentary movement. Journal of Biomechanics 31:3, pages 247-252.
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Markus H. Pettil??Seppo Sarna, Pekka Paavolainen & Jarl-Erik E. Michelsson. (1997) Short Term External Support Promotes Healing in Semirigidly Fixed Fractures. Clinical Orthopaedics and Related Research 343, pages 157???163.
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Lutz Claes, Peter Augat, Gebhard Suger & Hans‐Joachim Wilke. (2005) Influence of size and stability of the osteotomy gap on the success of fracture healing. Journal of Orthopaedic Research 15:4, pages 577-584.
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K. Hietaniemi, J. Peltonen & P. Paavolainen. (1995) An experimental model for non-union in rats. Injury 26:10, pages 681-686.
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P. Törmälä, J. Vasenius, S. Vainionpää, J. Laiho, T. Pohjonen & P. Rokkanen. (2004) Ultra‐high‐strength absorbable self‐reinforced polyglycolide (SR‐PGA) composite rods for internal fixation of bone fractures: In vitro and in vivo study . Journal of Biomedical Materials Research 25:1, pages 1-22.
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Yasuo Usui, Joseph E. Zerwekh, Heikki Vanharanta, Richard B. Ashman & Vert Mooney. (2005) Different effects of mechanical vibration on bone ingrowth into porous hydroxyapatite and fracture healing in a rabbit model. Journal of Orthopaedic Research 7:4, pages 559-567.
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A. Nesbakken, A. Alho, A. J. Bjersand, D. K. Jensen, L. Stangeland & A. Wall�e. (1988) Open tibial fractures treated with Hoffmann external fixation. Archives of Orthopaedic and Traumatic Surgery 107:4, pages 248-252.
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O. Korkala, E. Karaharju, M. Gr�nblad & K. Aalto. (1988) Experimental lengthening of tibial diaphysis: Gap healing with or without gradual distraction. Archives of Orthopaedic and Traumatic Surgery 107:3, pages 172-175.
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Anders O. Mølster, Nils R. Gjerdet, Norvald Langeland, Jon Lekven & Antti Alho. (2005) Controlled bending instability in the healing of diaphyseal osteotomies in the rat femur. Journal of Orthopaedic Research 5:1, pages 29-35.
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O. Reiker�s & A. Reigstad. (1985) Healing of stable and unstable osteotomies in rats. Archives of Orthopaedic and Traumatic Surgery 104:3, pages 161-163.
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H. Aro, E. Eerola & A. J. Aho. (2005) Determination of callus quantity in 4‐ week‐old fractures of the rat tibia. Journal of Orthopaedic Research 3:1, pages 101-108.
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