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Acta Orthopaedica Scandinavica Volume 62, 1991 - Issue 3
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Original Article

Growth hormone promotes healing of tibial fractures in the rat

Hanne M. Nielsen Department of Connective Tissue Biology, Institute of Anatomy, University of Århus, DK-8000, Århus C, Denmark, Tel +45-86128077, Fax +45-198664
,
Bue Bak Department of Connective Tissue Biology, Institute of Anatomy, University of Århus, DK-8000, Århus C, Denmark, Tel +45-86128077, Fax +45-198664
,
Peter H. Jørgensen Department of Connective Tissue Biology, Institute of Anatomy, University of Århus, DK-8000, Århus C, Denmark, Tel +45-86128077, Fax +45-198664
&
Troels T. Andreassen Department of Connective Tissue Biology, Institute of Anatomy, University of Århus, DK-8000, Århus C, Denmark, Tel +45-86128077, Fax +45-198664
Pages 244-247 | Received 02 Nov 1990, Accepted 01 Feb 1991, Published online: 08 Jul 2009

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Gui Tong Tran, Joseph Pagkalos, Evgenios Tsiridis, Amir Ali Narvani, Manolis Heliotis, Athanasios Mantalaris & Eleftherios Tsiridis. (2009) Growth hormone: does it have a therapeutic role in fracture healing?. Expert Opinion on Investigational Drugs 18:7, pages 887-911.
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Per H Morberg, Olle G P Isaksson, Carina B Johansson, Jonas Sandstedt & Jan F Törnell. (1997) Improved long-term bone-implant integration Experiments in transgenic mice overexpressing bovine growth hormone. Acta Orthopaedica Scandinavica 68:4, pages 344-348.
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Articles from other publishers (21)

Francisco G.F. TresguerresIsabel F. TresguerresIsabel LecoCelia ClementeRosa Rodríguez-TorresJesús TorresJorge CarballidoJesús A.F. Tresguerres. (2021) Growth Hormone As Antiaging Factor in Old Bones. Rejuvenation Research 24:5, pages 354-365.
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David J. Kirby, Daniel B. Buchalter, Utkarsh Anil & Philipp Leucht. (2020) DHEA in bone: the role in osteoporosis and fracture healing. Archives of Osteoporosis 15:1.
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Leonardo Tonietto, Andres F Vasquez, Luís A dos Santos & João BB Weber. (2018) Histological and structural evaluation of growth hormone and PLGA incorporation in macroporous scaffold of α-tricalcium phosphate cement. Journal of Biomaterials Applications 33:6, pages 866-875.
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Vittorio Locatelli & Vittorio E. Bianchi. (2014) Effect of GH/IGF-1 on Bone Metabolism and Osteoporsosis. International Journal of Endocrinology 2014, pages 1-25.
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Fernando Muñoz, Mónica López-Peña, Natalia Miño, Gerardo Gómez-Moreno, Javier Guardia & Antonio Cutando. (2012) Topical Application of Melatonin and Growth Hormone Accelerates Bone Healing around Dental Implants in Dogs. Clinical Implant Dentistry and Related Research 14:2, pages 226-235.
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Lutz Claes, Stefan Recknagel & Anita Ignatius. (2012) Fracture healing under healthy and inflammatory conditions. Nature Reviews Rheumatology 8:3, pages 133-143.
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Assem M. Hossam Eldein, Sherif H. Elghamrawy, Saeeda M. Osman & Amal R. Elhak. (2011) Histological Evaluation of the Effect of Using Growth Hormone Around Immediate Dental Implants in Fresh Extraction Sockets: An Experimental Study. Implant Dentistry 20:1, pages 47-55.
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Stefan Weiss, Philipp Henle, Martin Bidlingmaier, Arash Moghaddam, Philip Kasten & Gerald Zimmermann. (2008) Systemic response of the GH/IGF-I axis in timely versus delayed fracture healing. Growth Hormone & IGF Research 18:3, pages 205-212.
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Bruce Doll, Matthew Aleef & Jeffrey O. Hollinger. 2008. Musculoskeletal Tissue Regeneration. Musculoskeletal Tissue Regeneration 39 61 .
R. Giardino, P. Torricelli, G. Giavaresi, M. Fini, N.Nicoli Aldini, G. Ruggeri, M. Lima & A. Carpi. (2004) Histomorphometric bone modifications induced by growth hormone treatment in a rabbit model of short bowel syndrome. Biomedicine & Pharmacotherapy 58:2, pages 116-122.
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G. Schmidmaier, B. Wildemann, M. Lübberstedt, N.P. Haas & M. Raschke. (2003) IGF-I and TGF-Beta 1 incorporated in a poly(D,L-lactide) implant coating stimulates osteoblast differentiation and collagen-1 production but reduces osteoblast proliferation in cell culture. Journal of Biomedical Materials Research Part B: Applied Biomaterials 65B:1, pages 157-162.
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H.J Bail, M.J Raschke, S Kolbeck, G Krummrey, H.J Windhagen, A Weiler, K Raun, Li Mosekilde & N.P Haas. (2002) Recombinant species-specific growth hormone increases hard callus formation in distraction osteogenesis. Bone 30:1, pages 117-124.
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H.J. Bail, S. Kolbeck, T. Lindner, M. Dahne, A. Weiler, H.J. Windhagen, K. Raun, C. Skjaerbaek, A. Flyvbjerg, H. Ørskov, N.P. Haas & M.J. Raschke. (2001) The effect of growth hormone on insulin-like growth factor I and bone metabolism in distraction osteogenesis. Growth Hormone & IGF Research 11:5, pages 314-323.
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M Raschke, S Kolbeck, H Bail, G Schmidmaier, A Flyvbjerg, T Lindner, M Dahne, I.-A Roenne & N Haas. (2001) Homologous growth hormone accelerates healing of segmental bone defects. Bone 29:4, pages 368-373.
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Darryl L. Millis. (1999) Bone- and Non–Bone-Derived Growth Factors and Effects on Bone Healing. Veterinary Clinics of North America: Small Animal Practice 29:5, pages 1221-1246.
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M.J Raschke, H Bail, H.J Windhagen, S.F Kolbeck, A Weiler, K Raun, A Kappelgard, C Skiaerbaek & N.P Haas. (1999) Recombinant growth hormone accelerates bone regenerate consolidation in distraction osteogenesis. Bone 24:2, pages 81-88.
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Roman A. Hayda, Carl T. Brighton & John L. EsterhaiJr.Jr.. (1998) Pathophysiology of Delayed Healing. Clinical Orthopaedics and Related Research 355S, pages S31-S40.
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DARRYL L. MILLIS, BRENT E. WTLKENS, GREGORY B. DANIEL, KARL HUBNER, ARCHIE MATHEWS, FRANCES C. BUONOMO, KANAIYALA R. PATELL & JOSEPH P. WEIGEL. (2008) Radiographic, Densitometric, and Biomechanical Effects of Recombinant Canine Somatotropin in an Unstable Ostectomy Gap Model of Bone Healing in Dogs. Veterinary Surgery 27:2, pages 85-93.
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Claes OhlssonBengt-Åke BengtssonOlle G. P. IsakssonTroels T. AndreassenMaria C. Slootweg. (1998) Growth Hormone and Bone*. Endocrine Reviews 19:1, pages 55-79.
Crossref
P. Morberg, O. Isaksson, C. B. Johansson, J. Sandstedt & J. T�rnell. (1995) Improved early bone-implant integration in transgenic mice overexpressing bovine growth hormone. Journal of Materials Science: Materials in Medicine 6:9, pages 541-544.
Crossref
R. Tarvainen, H. Olkkonen, T. Nevalainen, P. Hyvönen, I. Arnala & E. Alhava. (1994) Effect of clodronate on fracture healing in denervated rats. Bone 15:6, pages 701-705.
Crossref

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