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Original Article

MMP-8 (neutrophil collagenase) mRNA and aggrecanase cleavage products are present in normal and osteoarthritic human articular cartilage

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Pages 98-102 | Published online: 08 Jul 2009

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Timo Sorsa, Leo Tjäderhane, Yrjö T. Konttinen, Anneli Lauhio, Tuula Salo, Hsi‐Ming Lee, Lorne M. Golub, David L. Brown & Päivi Mäntylä. (2006) Matrix metalloproteinases: Contribution to pathogenesis, diagnosis and treatment of periodontal inflammation. Annals of Medicine 38:5, pages 306-321.
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Birgitte Volck, Keld Østergaard, Julia Johansen, Charly Garbarsch, P.A Price. (1999) The Distribution of YKL-40 in Osteoarthritic and Normal Human Articular Cartilage. Scandinavian Journal of Rheumatology 28:3, pages 171-179.
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David C. Van Sickle & Sharon A. Evander. (1997) The Enigma of Adult and Immature Articular Cartilage. Journal of Histotechnology 20:3, pages 243-252.
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Articles from other publishers (21)

Katrin Sauerland, Amela Wolf, Manfred Schudok & Juergen Steinmeyer. (2021) A novel model of a biomechanically induced osteoarthritis‐like cartilage for pharmacological in vitro studies. Journal of Cellular and Molecular Medicine 25:24, pages 11221-11231.
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L. Fuentes, M. Yakob & D. T. W. Wong. (2014) Emerging horizons of salivary diagnostics for periodontal disease. British Dental Journal 217:10, pages 567-573.
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H Clarke Anderson, Douglas Mulhall & Rama Garimella. (2010) Role of extracellular membrane vesicles in the pathogenesis of various diseases, including cancer, renal diseases, atherosclerosis, and arthritis. Laboratory Investigation 90:11, pages 1549-1557.
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Hongyan Wang, Samuel Parry, George Macones, Mary D. Sammel, Pedro E. Ferrand, Helena Kuivaniemi, Gerard Tromp, Indrani Halder, Mark D. Shriver, Roberto Romero & Jerome F. StraussIIIIII. (2004) Functionally significant SNP MMP8 promoter haplotypes and preterm premature rupture of membranes (PPROM). Human Molecular Genetics 13:21, pages 2659-2669.
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Hidefumi OSHITA, John D. SANDYKiichi SUZUKI, Atsushi AKAIKE, Yun BAITomohiro SASAKI & Katsuji SHIMIZU. (2004) Mature bovine articular cartilage contains abundant aggrecan that is C-terminally truncated at Ala719-Ala720, a site which is readily cleaved by m-calpain. Biochemical Journal 382:1, pages 253-259.
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Kaiu Prikk, Päivi Maisi, Emma Pirilä, Mari-Ann Reintam, Tuula Salo, Timo Sorsa & Ruth Sepper. (2002) Airway Obstruction Correlates with Collagenase-2 (MMP-8) Expression and Activation in Bronchial Asthma. Laboratory Investigation 82:11, pages 1535-1545.
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J. Flannelly, M.G. Chambers, J. Dudhia, R.M. Hembry, G. Murphy, R.M. Mason & M.T. Bayliss. (2002) Metalloproteinase and tissue inhibitor of metalloproteinase expression in the murine STR/ort model of osteoarthritis. Osteoarthritis and Cartilage 10:9, pages 722-733.
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Magda Gioia, Giovanni Francesco Fasciglione, Stefano Marini, Silvana D'Alessio, Giampiero De Sanctis, Oliver Diekmann, Michael Pieper, Vincenzo Politi, Harald Tschesche & Massimo Coletta. (2002) Modulation of the Catalytic Activity of Neutrophil Collagenase MMP-8 on Bovine Collagen I. Journal of Biological Chemistry 277:26, pages 23123-23130.
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Wolfgang Eger, Barbara L. Schumacher, Jürgen Mollenhauer, Klaus E. Kuettner & Ada A. Cole. (2002) Human knee and ankle cartilage explants: Catabolic differences. Journal of Orthopaedic Research 20:3, pages 526-534.
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Thomas Aigner, Alexander Zien, Angelika Gehrsitz, Pia Margarethe Gebhard & Louise McKenna. (2001) Anabolic and catabolic gene expression pattern analysis in normal versus osteoarthritic cartilage using complementary DNA-array technology. Arthritis & Rheumatism 44:12, pages 2777-2789.
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Kaiu Prikk, Emma Piril�, Ruth Sepper, P�ivi Maisi, Tuula Salo, Jaana Wahlgren & Timo Sorsa. (2001) In vivo collagenase-2 (MMP-8) expression by human bronchial epithelial cells and monocytes/macrophages in bronchiectasis. The Journal of Pathology 194:2, pages 232-238.
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Jürgen Mollenhauer, Meng Tuck Mok, Karen B. King, Malini Gupta, Susan Chubinskaya, Holger Koepp & Ada A. Cole. (2016) Expression of Anchorin CII (Cartilage Annexin V) in Human Young, Normal Adult, and Osteoarthritic Cartilage. Journal of Histochemistry & Cytochemistry 47:2, pages 209-220.
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Shou-Ih Hu, Melissa Klein, Marc Carozza, John Rediske, Jane Peppard & Jian-Shen Qi. (1999) Identification of a splice variant of neutrophil collagenase (MMP-8). FEBS Letters 443:1, pages 8-10.
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Philippe Goupille, Malcom I. V. Jayson, Jean-Pierre Valat & Anthony J. Freemont. (1998) Matrix Metalloproteinases: The Clue to Intervertebral Disc Degeneration?. Spine 23:14, pages 1612-1626.
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Susan Chubinskaya, Gabriella Cs-Szabo & Klaus E. Kuettner. (2016) ADAM-10 Message Is Expressed in Human Articular Cartilage. Journal of Histochemistry & Cytochemistry 46:6, pages 723-729.
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Jürgen Steinmeyer, Sabine Daufeldt & Yetunde O. Taiwo. (1998) Pharmacological effect of tetracyclines on proteoglycanases from interleukin-1 -treated articular cartilage. Biochemical Pharmacology 55:1, pages 93-100.
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Roeland Hanemaaijer, Timo Sorsa, Yrjö T. Konttinen, Yanli Ding, Meeri Sutinen, Hetty Visser, Victor W.M. van Hinsbergh, Tarja Helaakoski, Tiina Kainulainen, Hanne Rönkä, Harald Tschesche & Tuula Salo. (1997) Matrix Metalloproteinase-8 Is Expressed in Rheumatoid Synovial Fibroblasts and Endothelial Cells. Journal of Biological Chemistry 272:50, pages 31504-31509.
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Boris V. Shlopov, Wen-Rong Lie, Carlo L. Mainardi, Ada A. Cole, Susan Chubinskaya & Karen A. Hasty. (1997) Osteoarthritic Lesions. Involvement of three different collagenases. Arthritis & Rheumatism 40:11, pages 2065-2074.
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Jürgen Steinmeyer & Sabine Daufeldt. (1997) Pharmacological influence of antirheumatic drugs on proteoglycanases from interleukin-1 treated articular cartilage. Biochemical Pharmacology 53:11, pages 1627-1635.
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Jürgen Steinmeyer, Sabine Daufeldt & Dieter A. Kalbhen. (2014) The proteoglycan metabolism, morphology and viability of articular cartilage treated with a synthetic matrix metalloproteinase inhibitor. Research in Experimental Medicine 197:2, pages 63-79.
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Ada A. Cole, Susan Chubinskaya, Barbara Schumacher, Klaus Huch, Gabriella Cs-Szabo, Jianling Yao, Katalin Mikecz, Karen A. Hasty & Klaus E. Kuettner. (1996) Chondrocyte Matrix Metalloproteinase-8. Journal of Biological Chemistry 271:18, pages 11023-11026.
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