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Original Article

Anabolic and catabolic markers of proteoglycan metabolism in osteoarthritis

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Pages 121-124 | Published online: 08 Jul 2009

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L Stefan Lohrnander, Harald Roos, Leif Dahlberg & Michael W Lark. (1995) The role of molecular markers to monitor disease, intervention and cartilage breakdown in osteoarthritis. Acta Orthopaedica Scandinavica 66:sup266, pages 84-87.
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Articles from other publishers (33)

Haoyu Yang, Zhicheng Yang, Zhentang Yu, Chenwei Xiong, Yi Zhang, Junjie Zhang, Yong Huang, Xindie Zhou, Jin Li & Nanwei Xu. (2022) SEMA6D, Negatively Regulated by miR-7, Contributes to C28/I2 chondrocyte’s Catabolic and Anabolic Activities via p38 Signaling Pathway. Oxidative Medicine and Cellular Longevity 2022, pages 1-16.
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Ahreum Baek, Yoon Kim, Jin Woo Lee, Sang Chul Lee & Sung-Rae Cho. (2018) Effect of Polydeoxyribonucleotide on Angiogenesis and Wound Healing in an In Vitro Model of Osteoarthritis . Cell Transplantation 27:11, pages 1623-1633.
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Gregory D. Jay, Braden C. Fleming, Bryn A. Watkins, Karen A. McHugh, Scott C. Anderson, Ling X. Zhang, Erin Teeple, Kimberly A. Waller & Khaled A. Elsaid. (2010) Prevention of cartilage degeneration and restoration of chondroprotection by lubricin tribosupplementation in the rat following anterior cruciate ligament transection. Arthritis & Rheumatism 62:8, pages 2382-2391.
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Elaine R. Garvican, Anne Vaughan-Thomas, Peter D. Clegg & John F. Innes. (2010) Biomarkers of cartilage turnover. Part 2: Non-collagenous markers. The Veterinary Journal 185:1, pages 43-49.
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Linda Troeberg, Kazunari Fushimi, Rama Khokha, Hervé Emonard, Peter Ghosh & Hideaki Nagase. (2008) Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases. The FASEB Journal 22:10, pages 3515-3524.
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Anthony J. Hayes, Clare E. Hughes & Bruce Caterson. (2008) Antibodies and immunohistochemistry in extracellular matrix research. Methods 45:1, pages 10-21.
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Anthony J. Hayes, Debbie Tudor, Mari A. Nowell, Bruce Caterson & Clare E. Hughes. (2007) Chondroitin Sulfate Sulfation Motifs as Putative Biomarkers for Isolation of Articular Cartilage Progenitor Cells. Journal of Histochemistry & Cytochemistry 56:2, pages 125-138.
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Korakot NganvongpanitAkanit ItthiarbhaSiriwan Ong-ChaiPrachya Kongtawelert. (2008) Evaluation of serum chondroitin sulfate and hyaluronan: biomarkers for osteoarthritis in canine hip dysplasia. Journal of Veterinary Science 9:3, pages 317.
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Peraphan Pothacharoen, Kittiwan Kalayanamitra, Sarama S. Deepa, Shigeyuki Fukui, Tomohide Hattori, Nobuhiro Fukushima, Timothy Hardingham, Prachya Kongtawelert & Kazuyuki Sugahara. (2007) Two Related but Distinct Chondroitin Sulfate Mimetope Octasaccharide Sequences Recognized by Monoclonal Antibody WF6. Journal of Biological Chemistry 282:48, pages 35232-35246.
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Sarah G. Rees, Andrew D. Waggett, Colin M. Dent & Bruce Caterson. (2007) Inhibition of aggrecan turnover in short-term explant cultures of bovine tendon. Matrix Biology 26:4, pages 280-290.
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John F. Innes, Chris B. Little, Clare E. Hughes & Bruce Caterson. (2005) Products resulting from cleavage of the interglobular domain of aggrecan in samples of synovial fluid collected from dogs with early- and late-stage osteoarthritis. American Journal of Veterinary Research 66:10, pages 1679-1685.
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C.B. Little, C.R. Flannery, C.E. Hughes, A. Goodship & B. Caterson. (2005) Cytokine induced metalloproteinase expression and activity does not correlate with focal susceptibility of articular cartilage to degeneration. Osteoarthritis and Cartilage 13:2, pages 162-170.
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K. A. Johnson, D. J. Francis, P. A. Manley, Q. Chu & B. Caterson. (2004) Comparison of the effects of caudal pole hemi-meniscectomy and complete medial meniscectomy in the canine stifle joint. American Journal of Veterinary Research 65:8, pages 1053-1060.
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Lisa A Collins-Racie, Carl R Flannery, Weilan Zeng, Chris Corcoran, Bethany Annis-Freeman, Michael J Agostino, Maya Arai, Elizabeth DiBlasio-Smith, Andrew J Dorner, Katy E Georgiadis, Macy Jin, Xiang-Yang Tan, Elisabeth A Morris & Edward R LaVallie. (2004) ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage. Matrix Biology 23:4, pages 219-230.
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Claire L. Harris, Clare E. Hughes, Anwen S. Williams, Ian Goodfellow, David J. Evans, Bruce Caterson & B.Paul Morgan. (2003) Generation of Anti-complement “Prodrugs”. Journal of Biological Chemistry 278:38, pages 36068-36076.
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A. J. DART, C. B. LITTLE, C. E. HUGHES, Q. CHU, B. A. DOWLING, D. R. HODGSON, R. J. ROSE & K. A. JOHNSON. (2010) Recombinant equine growth hormone administration: effects on synovial fluid biomarkers and cartilage metabolism in horses. Equine Veterinary Journal 35:3, pages 302-307.
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Wen-Ning Qi & Sean P. Scully. (2003) Type II collagen modulates the composition of extracellular matrix synthesized by articular chondrocytes. Journal of Orthopaedic Research 21:2, pages 282-289.
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Clare L. Curtis, Sarah G. Rees, Joanna Cramp, Carl R. Flannery, Clare E. Hughes, Chris B. Little, Rhys Williams, Chris Wilson, Colin M. Dent, John L. Harwood & Bruce Caterson. (2008) Effects of n -3 fatty acids on cartilage metabolism . Proceedings of the Nutrition Society 61:3, pages 381-389.
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Q. Chu, M. Lopez, K. Hayashi, M. Ionescu, R.C. Billinghurst, K.A. Johnson, A.R. Poole & M.D. Markel. (2002) Elevation of a collagenase generated type II collagen neoepitope and proteoglycan epitopes in synovial fluid following induction of joint instability in the dog. Osteoarthritis and Cartilage 10:8, pages 662-669.
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Kenneth A. Johnson, Callum W. Hay, Qili Chu, Simon C. Roe & Bruce Caterson. (2002) Cartilage-derived biomarkers of osteoarthritis in synovial fluid of dogs with naturally acquired rupture of the cranial cruciate ligament. American Journal of Veterinary Research 63:6, pages 775-781.
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Heather A. Horner, Sally Roberts, Robert C. Bielby, Janis Menage, Helen Evans & Jill P. G. Urban. (2002) Cells From Different Regions of the Intervertebral Disc. Spine 27:10, pages 1018-1028.
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Christopher B. Little, Clare E. Hughes, Clare L. Curtis, Mike J. Janusz, Richard Bohne, Sherry Wang-Weigand, Yetunde O. Taiwo, Peter G. Mitchell, Ivan G. Otterness, Carl R. Flannery & Bruce Caterson. (2002) Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation. Matrix Biology 21:3, pages 271-288.
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Shinji Uesaka, Yoshihito Nakayama, Kiyoshi Yoshihara & Hiromoto Ito. (2002) Significance of chondroitin sulfate isomers in the synovial fluid of osteoarthritis patients. Journal of Orthopaedic Science 7:2, pages 232-237.
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Cathy S. Carlson, Farshid Guilak, Thomas P. Vail, Jean F. Gardin & Virginia B. Kraus. (2002) Synovial fluid biomarker levels predict articular cartilage damage following complete medial meniscectomy in the canine knee. Journal of Orthopaedic Research 20:1, pages 92-100.
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Anik Chevrier, John S. Mort, Philippe Crine, Caroline D. Hoemann & Michael D. Buschmann. (2001) Soluble Recombinant Neprilysin Induces Aggrecanase-Mediated Cleavage of Aggrecan in Cartilage Explant Cultures. Archives of Biochemistry and Biophysics 396:2, pages 178-186.
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Kenneth A. Johnson, Robert C. Hart, Qili Chu, Deborah Kochevar & Donald A. Hulse. (2001) Concentrations of chondroitin sulfate epitopes 3B3 and 7D4 in synovial fluid after intra-articular and extracapsular reconstruction of the cranial cruciate ligament in dogs. American Journal of Veterinary Research 62:4, pages 581-587.
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Shinji Uesaka, Yoshihito Nakayama, Yasumasa Shirai & Kiyoshi Yoshihara. (2001) Serum and Synovial Fluid Levels of Chondroitin Sulfate in Patients with Osteoarthritis of the Knee Joint. Journal of Nippon Medical School 68:2, pages 165-170.
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K.A. Johnson, D.A. Hulse, R.C. Hart, D. Kochevar & Q. Chu. (2001) Effects of an orally administered mixture of chondroitin sulfate, glucosamine hydrochloride and manganese ascorbate on synovial fluid chondroitin sulfate 3B3 and 7D4 epitope in a canine cruciate ligament transection model of osteoarthritis. Osteoarthritis and Cartilage 9:1, pages 14-21.
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Roberts, Caterson, Menage, Evans & Eisenstein. (2008) Enzyme degradation products in human intervertebral disc. International Journal of Experimental Pathology 81:1, pages A22-A23.
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Yoshihito Nakayama, Yasumasa Shirai, Kiyoshi Yoshihara & Shinji Uesaka. (2000) Evaluation of Glycosaminoglycans Levels in Normal Joint Fluid of the Knee.. Journal of Nippon Medical School 67:2, pages 92-95.
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J. Middleton, S. White, E. Parry, C. Jackson, J. Dixey & B. Ashton. (1999) Changes in serum chondroitin sulphate epitopes 3-B-3 and 7-D-4 in early rheumatoid arthritis. Rheumatology 38:9, pages 837-840.
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Stephen L. Myers. (1999) SYNOVIAL FLUID MARKERS IN OSTEOARTHRITIS. Rheumatic Disease Clinics of North America 25:2, pages 433-449.
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James Melrose, Christopher B. Little & Peter Ghosh. (1998) Detection of Aggregatable Proteoglycan Populations by Affinity Blotting Using Biotinylated Hyaluronan. Analytical Biochemistry 256:2, pages 149-157.
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