Advanced search
Publication Cover
International Journal of Pediatric Obesity Volume 5, 2010 - Issue 4
Journal homepage
801
Views
154
CrossRef citations to date
0
Altmetric
REVIEW ARTICLE

Artificial Sweeteners: A systematic review of metabolic effects in youth

Rebecca J. Brown National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USACorrespondence[email protected]
,
Mary Ann de Banate National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
&
Kristina I. Rother National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
Pages 305-312 | Received 27 May 2009, Accepted 30 Oct 2009, Published online: 18 Jan 2010

Citations (154)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (9)

Emilia Sokołowska, Anna Sadowska, Diana Sawicka, Izabela Kotulska-Bąblińska & Halina Car. (2022) A head-to-head comparison review of biological and toxicological studies of isomaltulose, d-tagatose, and trehalose on glycemic control. Critical Reviews in Food Science and Nutrition 62:21, pages 5679-5704.
Read now
Azadeh Tavakoli & Judith Louise Flanagan. (2022) Dry eye disease: an (in)convenient truth. Clinical and Experimental Optometry 105:2, pages 222-229.
Read now
Samuel Mendoza-Pérez, Rolando Salvador García-Gómez, Guillermo Ordaz-Nava, María Isabel Gracia-Mora, Lucía Macías-Rosales, Héctor Morales-Rico, Gerardo Salas-Garrido, Elia Martha Pérez-Armendáriz, Ruth Bustamante-García & María-del-Carmen Durán-Domínguez-de-Bazúa. (2021) Consumption of sweeteners at different stages of life: effects on body mass, food and drink intake in male and female Wistar rats. International Journal of Food Sciences and Nutrition 72:7, pages 935-946.
Read now
Marquitta C. Webb, Dana Chong & Sa’eed Bawa. (2021) Consumption patterns of nonnutritive sweeteners among university students at a Caribbean institution. Journal of American College Health 69:7, pages 719-724.
Read now
Roberto Castro-Muñoz, Elsa Díaz-Montes, Alfredo Cassano & Emilia Gontarek. (2021) Membrane separation processes for the extraction and purification of steviol glycosides: an overview. Critical Reviews in Food Science and Nutrition 61:13, pages 2152-2174.
Read now
Amar D. E. Van Laar, Charlotte Grootaert & John Van Camp. (2021) Rare mono- and disaccharides as healthy alternative for traditional sugars and sweeteners?. Critical Reviews in Food Science and Nutrition 61:5, pages 713-741.
Read now
Lisa Miclotte & Tom Van de Wiele. (2020) Food processing, gut microbiota and the globesity problem. Critical Reviews in Food Science and Nutrition 60:11, pages 1769-1782.
Read now
Armorel Diane van Eyk. (2015) The effect of five artificial sweeteners on Caco-2, HT-29 and HEK-293 cells. Drug and Chemical Toxicology 38:3, pages 318-327.
Read now
Tracey A Ledoux, Kathy Watson, Anthony Barnett, Nga T Nguyen, Janice C Baranowski & Tom Baranowski. (2011) Components of the Diet Associated with Child Adiposity: A Cross-Sectional Study. Journal of the American College of Nutrition 30:6, pages 536-546.
Read now

Articles from other publishers (145)

Sanjeev K. Bhardwaj, Akash Deep, Neha Bhardwaj & Nishima Wangoo. (2023) Recent advancements in nanomaterial based optical detection of food additives: a review. The Analyst 148:21, pages 5322-5339.
Crossref
Habiba Samreen & Suneela Dhaneshwar. (2023) Artificial Sweeteners: Perceptions and Realities. Current Diabetes Reviews 19:7.
Crossref
Zi-wei Chen, Zhi-wei Shen, Zu-lin Hua & Xiao-qing Li. (2023) Global development and future trends of artificial sweetener research based on bibliometrics. Ecotoxicology and Environmental Safety 263, pages 115221.
Crossref
Ab Qayoom Naik, Tabassum Zafar & Vinoy K Shrivastava. (2023) The impact of non-caloric artificial sweetener aspartame on female reproductive system in mice model. Reproductive Biology and Endocrinology 21:1.
Crossref
Halis K Akturk, Janet Snell-Bergeon, Kagan E Karakus & Viral N Shah. (2023) Assessing the relationship between low-calorie sweetener use and quality of life measures in adults with type 1 diabetes. BMC Endocrine Disorders 23:1.
Crossref
Sandeep Singh, Aditya Kohli, Stuti Trivedi, Sai Gautham Kanagala, F. N. U. Anamika, Nikita Garg, Meet A. Patel, Ripudaman Singh Munjal & Rohit Jain. (2023) The contentious relationship between artificial sweeteners and cardiovascular health. The Egyptian Journal of Internal Medicine 35:1.
Crossref
Ji Liu, Haiying Du, Yuqiu Jiang, Lanying Zhang, Yanqi Ma, Bingjie Fu, Yao Hu & Heng Kang. (2023) A label-free Eupatorium odoratum L. CQDs-based fluorescence sensor as a “turn-on” type for effective detecting of artificial sweetener. Journal of Materials Science: Materials in Electronics 34:17.
Crossref
Suresh Nagaral, Kamran Habib Awan, Sudha Patil, Hosam Ali Baeshen, Joshua Finch, Shankargouda Patil, Rua Adnan Saeed Jalal, Dhalia Hassan Albar, Sandesh Jagdish Bansal & Christopher Alexander Bernard. (2023) Intake of Artificial Sweeteners by Children: Boon or Bane?. The Journal of Contemporary Dental Practice 24:2, pages 137-145.
Crossref
Husni Mohammed Hasan, Suad Yousif Alkass & Daniele Suzete Persike de Oliveira. (2023) Impact of Long-Term Cyclamate and Saccharin Consumption on Biochemical Parameters in Healthy Individuals and Type 2 Diabetes Mellitus Patients. Medicina 59:4, pages 698.
Crossref
Madhu Goud Ediga, Suvarna Annapureddy, Kishore Salikineedy & Mallikarjuna Nimgampalle. (2023) Aspartame consumption causes cognitive impairment in streptozotocin-induced diabetic Wistar rats. Biologia.
Crossref
Xiaopeng Yu, Furong Yu, Zhiping Li, Tongyang Shi, Zhiguo Xia & Guangning Li. (2023) Occurrence, distribution, and ecological risk assessment of artificial sweeteners in surface and ground waters of the middle and lower reaches of the Yellow River (Henan section, China). Environmental Science and Pollution Research 30:18, pages 52609-52623.
Crossref
John R. Rossiter. (2022) “Sugary drinks” and graphic warning labels: Critique of a recent U.S. study of parents' beverage choices for their children. Journal of Consumer Behaviour 22:1, pages 170-176.
Crossref
Ertan Celik, Merve Ercin, Sehnaz Bolkent & Selda Gezginci-Oktayoglu. (2022) Metformin induces mitochondrial remodeling and differentiation of pancreatic progenitor cells into beta-cells by a potential mechanism including suppression of the T1R3, PLCβ2, cytoplasmic Ca+2, and AKT. Journal of Physiology and Biochemistry 78:4, pages 869-883.
Crossref
Katsumi Iizuka. (2022) Is the Use of Artificial Sweeteners Beneficial for Patients with Diabetes Mellitus? The Advantages and Disadvantages of Artificial Sweeteners. Nutrients 14:21, pages 4446.
Crossref
Aylin Bayındır Gümüş, Alev Keser, Esra Tunçer, Tuğba Altuntaş Yıldız & İlknur Kepenekci Bayram. (2022) Effect of saccharin, a non-nutritive sweeteners, on insulin and blood glucose levels in healthy young men: A crossover trial. Diabetes & Metabolic Syndrome: Clinical Research & Reviews 16:6, pages 102500.
Crossref
Carmen Gloria González, Camila Corvalán & Marcela Reyes. (2022) Sweetness of Chilean Infants’ Diets: Methodology and Description. Nutrients 14:7, pages 1447.
Crossref
Ottavio D'Urso & Filippo Drago. (2021) Pharmacological significance of extra-oral taste receptors. European Journal of Pharmacology 910, pages 174480.
Crossref
Rafael Pérez‐Escamilla, Mireya Vilar‐Compte, Elizabeth Rhodes, Olga L. Sarmiento, Camila Corvalan, Rachel SturkeSusan Vorkoper. (2021) Implementación de políticas de prevención y control de la obesidad infantil en Estados Unidos y Latinoamérica: lecciones para la investigación y la práctica transfronterizas. Obesity Reviews 22:S5.
Crossref
Luisa Bonsembiante, Giovanni Targher & Claudio Maffeis. (2021) Type 2 Diabetes and Dietary Carbohydrate Intake of Adolescents and Young Adults: What Is the Impact of Different Choices?. Nutrients 13:10, pages 3344.
Crossref
Abigail Raffner Basson, Alexander Rodriguez-Palacios & Fabio Cominelli. (2021) Artificial Sweeteners: History and New Concepts on Inflammation. Frontiers in Nutrition 8.
Crossref
Sage Arbor. 2021. Sugar Intake - Risks and Benefits and the Global Diabetes Epidemic. Sugar Intake - Risks and Benefits and the Global Diabetes Epidemic.
Tamryn Frank, Anne-Marie Thow, Shu Wen Ng, Jessica Ostrowski, Makoma Bopape & Elizabeth C. Swart. (2021) A Fit-for-Purpose Nutrient Profiling Model to Underpin Food and Nutrition Policies in South Africa. Nutrients 13:8, pages 2584.
Crossref
Han Youl Lee, Maia Jack, Theresa Poon, Daniel Noori, Carolina Venditti, Samer Hamamji & Kathy Musa-Veloso. (2021) Effects of Unsweetened Preloads and Preloads Sweetened with Caloric or Low-/No-Calorie Sweeteners on Subsequent Energy Intakes: A Systematic Review and Meta-Analysis of Controlled Human Intervention Studies. Advances in Nutrition 12:4, pages 1481-1499.
Crossref
Mie Normand, Christian Ritz, David Mela & Anne Raben. (2021) Low-energy sweeteners and body weight: a citation network analysis. BMJ Nutrition, Prevention & Health 4:1, pages 319-332.
Crossref
Rafael Pérez‐Escamilla, Mireya Vilar‐Compte, Elizabeth Rhodes, Olga L. Sarmiento, Camila Corvalan, Rachel Sturke & Susan Vorkoper. (2021) Implementation of childhood obesity prevention and control policies in the United States and Latin America: Lessons for cross‐border research and practice. Obesity Reviews 22:S3.
Crossref
Ana Laura Velázquez, Leticia Vidal, Paula Varela & Gastón Ares. (2021) Sugar reduction in products targeted at children: Why are we not there yet?. Journal of Sensory Studies.
Crossref
Jariyah, E M N Arofah & U Sarofa. (2021) Characteristics and Anti-Diabetics Activity of Jelly Drink Okra Mucus (Abelmoschus Escullentus L.). Journal of Physics: Conference Series 1899:1, pages 012023.
Crossref
Guangxi Han, Xiang Li, Gaopan Dong, Ling Zhang, Jianxiang Gao, Minyong Li & Lupei Du. (2021) Phenotyping Aquatic Neurotoxicity Induced by the Artificial Sweetener Saccharin at Sublethal Concentration Levels. Journal of Agricultural and Food Chemistry 69:7, pages 2041-2050.
Crossref
Qing Shi, Xuemei Zhu & Shaoping Deng. (2019) Sweet Taste Receptor Expression and Its Activation by Sucralose to Regulate Glucose Absorption in Mouse Duodenum. Journal of Food Science 86:2, pages 540-545.
Crossref
Marcela Sánchez-Delgado, José Antonio Estrada, Vladimir Paredes-Cervantes, Martha Kaufer-Horwitz & Irazú Contreras. (2021) Changes in nutrient and calorie intake, adipose mass, triglycerides and TNF-α concentrations after non-caloric sweetener intake: A pilot study. International Journal for Vitamin and Nutrition Research 91:1-2, pages 87-98.
Crossref
Laurent Chevallier. 2021. 65 Ordonnances Alimentaires. 65 Ordonnances Alimentaires 149 160 .
B. Vergès. 2021. Les Obésités. Les Obésités 97 101 .
Elsa Díaz-Montes, Octavio García-Depraect & Roberto Castro-Muñoz. 2021. Steviol Glycosides. Steviol Glycosides 159 199 .
Gaëlle Awad, Katia Befort & Mary C. Olmstead. 2021. Animal Models of Eating Disorders. Animal Models of Eating Disorders 115 131 .
Carolina Venegas Hargous, Marcela Reyes, Lindsey Smith Taillie, Carmen Gloria González & Camila Corvalán. (2020) Consumption of non-nutritive sweeteners by pre-schoolers of the food and environment Chilean cohort (FECHIC) before the implementation of the Chilean food labelling and advertising law. Nutrition Journal 19:1.
Crossref
Nondumiso Prosperity Mbambo, Siphiwe Ndumiso Dlamini, Chika Ifeanyi Chukwuma & Md. Shahidul Islam. (2020) Comparative effects of commonly used commercially available non‐nutritive sweeteners on diabetes‐related parameters in non‐diabetic rats. Journal of Food Biochemistry 44:11.
Crossref
Nastaran Salavati, Petra C. Vinke, Fraser Lewis, Marian K. Bakker, Jan Jaap H.M. Erwich & Eline M. M.van der Beek. (2020) Offspring Birth Weight Is Associated with Specific Preconception Maternal Food Group Intake: Data from a Linked Population-Based Birth Cohort. Nutrients 12:10, pages 3172.
Crossref
Andy Wai Kan Yeung & Natalie Sui Miu Wong. (2020) How Does Our Brain Process Sugars and Non-Nutritive Sweeteners Differently: A Systematic Review on Functional Magnetic Resonance Imaging Studies. Nutrients 12:10, pages 3010.
Crossref
Samar Y Ahmad, James K Friel & Dylan S Mackay. (2020) Effect of sucralose and aspartame on glucose metabolism and gut hormones. Nutrition Reviews 78:9, pages 725-746.
Crossref
Elsa Díaz-Montes, Paulina Gutiérrez-Macías, Carlos Orozco-Álvarez & Roberto Castro-Muñoz. (2020) Fractionation of Stevia rebaudiana aqueous extracts via two-step ultrafiltration process: towards rebaudioside a extraction. Food and Bioproducts Processing 123, pages 111-122.
Crossref
Agnieszka Piekara, Małgorzata Krzywonos & Anna Szymańska. (2020) Sweetening Agents and Sweeteners in Dietary Supplements for Children-Analysis of the Polish Market. Nutrients 12:8, pages 2387.
Crossref
Svetla Petrova & Valentina Christova-Bagdassarian. (2020) Analytical difficulties for determination of acesulfame K in chocolate products. Pharmacia 67:2, pages 105-110.
Crossref
Allison C. Sylvetsky, Avinash Chandran, Sameera A. Talegawkar, Jean A. Welsh, Kimberly Drews & Laure El ghormli. (2020) Consumption of Beverages Containing Low-Calorie Sweeteners, Diet, and Cardiometabolic Health in Youth With Type 2 Diabetes. Journal of the Academy of Nutrition and Dietetics 120:8, pages 1348-1358.e6.
Crossref
Alexandria Turner, Martin Veysey, Simon Keely, Christopher J. Scarlett, Mark Lucock & Emma L. Beckett. (2020) Intense Sweeteners, Taste Receptors and the Gut Microbiome: A Metabolic Health Perspective. International Journal of Environmental Research and Public Health 17:11, pages 4094.
Crossref
Jyoti Singh, Prasad Rasane, Sawinder Kaur, Vikas Kumar, Kajal Dhawan, Dipendra K. Mahato, Sunita Malhotra, Chayanika Sarma, Damanpreet Kaur & Jayatee Bhattacharya. (2020) Nutritional Interventions and Considerations for the Development of Low Calorie or Sugar Free Foods. Current Diabetes Reviews 16:4, pages 301-312.
Crossref
Ana Laura Velázquez, Leticia Vidal, Paula Varela & Gastón Ares. (2020) Cross-modal interactions as a strategy for sugar reduction in products targeted at children: Case study with vanilla milk desserts. Food Research International 130, pages 108920.
Crossref
Nadi F. Salaya-Velazquez, Luis A. López-Muciño, Sara Mejía-Chávez, Pedro Sánchez-Aparicio, Andrés A. Domínguez-Guadarrama & Arturo Venebra-Muñoz. (2020) Anandamide and sucralose change ΔFosB expression in the reward system. NeuroReport 31:3, pages 240-244.
Crossref
Hossein Miraji, Othman Chande Othman, Faustin Ngassapa & Mureithi Eunice. 2020. Effects of Emerging Chemical Contaminants on Water Resources and Environmental Health. Effects of Emerging Chemical Contaminants on Water Resources and Environmental Health 68 80 .
René Bailón Uriza, José Antonio Ayala Méndez, Brian Cavagnari, Cuauhtémoc Celis González, Rubén Chapa Tellez, Jesús Chávez Brambila, Alan Espinosa Marrón, Josefina Lira Plascencia, Mardia Guadalupe López Alarcón, Rebeca López García, Juan de Dios Maldonado Alvarado, Fernanda Molina Seguí, Javier Montoya Cossio, Jorge Méndez Trujeque, Victorina Nolascozhu Morán, Eduardo Sirahuén Neri Ruz, Antonio Erasto Peralta Sánchez, Martin Tulio Santa Rita Escamilla, Gilberto Tena Alavez, Pilar Riobó Serván & Hugo Laviada Molina. (2020) Non-caloric sweeteners in women of reproductive age – A consensus document. Nutrición Hospitalaria.
Crossref
Carissa M. Baker-SmithSarah D. de Ferranti, William J. Cochran, Steven A. Abrams, George J. FuchsIIIIII, Jae Hong Kim, C. Wesley Lindsey, Sheela N. Magge, Ellen S. Rome, Sarah Jane Schwarzenberg, Jenifer R. Lightdale, David Brumbaugh, Mitchell B. Cohen, Jennifer L. Dotson, Sanjiv Harpavat, Maria M. Oliva-Hemker & Leo A. Heitlinger. (2019) The Use of Nonnutritive Sweeteners in Children. Pediatrics 144:5.
Crossref
Allison C. Sylvetsky, Janet Figueroa, Talia Zimmerman, Susan E. Swithers & Jean A. Welsh. (2019) Consumption of low‐calorie sweetened beverages is associated with higher total energy and sugar intake among children, NHANES 2011–2016. Pediatric Obesity 14:10.
Crossref
B. E. Martínez-Carrillo, C. A. Rosales-Gómez, N. Ramírez-Durán, A. A. Reséndiz-Albor, J. A. Escoto-Herrera, T. Mondragón-Velásquez, R. Valdés-Ramos & A. Castillo-Cardiel. (2019) Effect of Chronic Consumption of Sweeteners on Microbiota and Immunity in the Small Intestine of Young Mice. International Journal of Food Science 2019, pages 1-16.
Crossref
A. M. van Opstal, A. A. van den Berg-Huysmans, M. Hoeksma, C. Blonk, H. Pijl, S. A. R. B. Rombouts & J. van der Grond. (2019) Effect of flavor on neuronal responses of the hypothalamus and ventral tegmental area. Scientific Reports 9:1.
Crossref
Jordan Young, Ellen M. Conway, Kristina I. Rother & Allison C. Sylvetsky. (2019) Low‐calorie sweetener use, weight, and metabolic health among children: A mini‐review. Pediatric Obesity 14:8.
Crossref
Nazli Aytekin, Banu Godfri & Adam Cunliffe. (2019) ‘The hunger trap hypothesis’: New horizons in understanding the control of food intake. Medical Hypotheses 129, pages 109247.
Crossref
Chang Hee LeeWon YunJi Hwan LeeWoo Gi KwakHan Jin OhJi Seon AnShu Dong LiuJin Ho Cho. (2019) Effects of artificial sweeteners on feed palatability and performance in weaned pigs. Canadian Journal of Animal Science 99:2, pages 307-314.
Crossref
Yi Jing, Thang S. Han, Majid M. Alkhalaf & Michael E. J. Lean. (2018) Attenuation of the association between sugar-sweetened beverages and diabetes risk by adiposity adjustment: a secondary analysis of national health survey data. European Journal of Nutrition 58:4, pages 1703-1710.
Crossref
Sarva Mangala Praveena, Manraj Singh Cheema & How-Ran Guo. (2019) Non-nutritive artificial sweeteners as an emerging contaminant in environment: A global review and risks perspectives. Ecotoxicology and Environmental Safety 170, pages 699-707.
Crossref
Iryna Liauchonak, Bessi Qorri, Fady Dawoud, Yatin Riat & Myron Szewczuk. (2019) Non-Nutritive Sweeteners and Their Implications on the Development of Metabolic Syndrome. Nutrients 11:3, pages 644.
Crossref
Jeffrey B. Schwimmer, Patricia Ugalde-Nicalo, Jean A. Welsh, Jorge E. Angeles, Maria Cordero, Kathryn E. Harlow, Adina Alazraki, Janis Durelle, Jack Knight-Scott, Kimberly P. Newton, Rebecca Cleeton, Cynthia Knott, Juna Konomi, Michael S. Middleton, Curtis Travers, Claude B. Sirlin, Albert Hernandez, Ahlia Sekkarie, Courtney McCracken & Miriam B. Vos. (2019) Effect of a Low Free Sugar Diet vs Usual Diet on Nonalcoholic Fatty Liver Disease in Adolescent Boys. JAMA 321:3, pages 256.
Crossref
Ingrid Toews, Szimonetta Lohner, Daniela Küllenberg de Gaudry, Harriet Sommer & Joerg J Meerpohl. (2019) Association between intake of non-sugar sweeteners and health outcomes: systematic review and meta-analyses of randomised and non-randomised controlled trials and observational studies. BMJ, pages k4718.
Crossref
Lígia Leão Pimentel, Ana Luiza Fontes, Ana Sofia Salsinha, Beatriz Batista Cardoso, Ana Maria Gomes & Luís Miguel Rodríguez-Alcalá. 2019. 369 394 .
Pariyarath S. Thondre & Miriam E. Clegg. 2019. Reformulation as a Strategy for Developing Healthier Food Products. Reformulation as a Strategy for Developing Healthier Food Products 7 64 .
ALONGKOTE SINGHATO, URAIPORN BOORANASUKSAKUL, SOMJET KHONGKHON & NARISA RUEANGSRI. (2018) Acceptability of a High Protein Snack Using Artificial Sweeteners for People Living with HIV with Oral Problems. Current Research in Nutrition and Food Science Journal 6:3, pages 711-719.
Crossref
Denise Kreuch, Damien J. Keating, Tongzhi Wu, Michael Horowitz, Christopher K. Rayner & Richard L. Young. (2018) Gut Mechanisms Linking Intestinal Sweet Sensing to Glycemic Control. Frontiers in Endocrinology 9.
Crossref
Katelyn M. Godin, David Hammond, Ashok Chaurasia & Scott T. Leatherdale. (2018) Examining changes in school vending machine beverage availability and sugar-sweetened beverage intake among Canadian adolescents participating in the COMPASS study: a longitudinal assessment of provincial school nutrition policy compliance and effectiveness. International Journal of Behavioral Nutrition and Physical Activity 15:1.
Crossref
A. K. Macintyre, L. Marryat & S. Chambers. (2018) Exposure to liquid sweetness in early childhood: artificially‐sweetened and sugar‐sweetened beverage consumption at 4–5 years and risk of overweight and obesity at 7–8 years. Pediatric Obesity 13:12, pages 755-765.
Crossref
Bruno Vergès. (2018) Les édulcorants sont-ils dangereux ?. Pratiques en nutrition 14:56, pages 25-28.
Crossref
Linia Patel, Gianfranco Alicandro & Carlo La Vecchia. (2018) Low-Calorie Beverage Consumption, Diet Quality and Cardiometabolic Risk Factors in British Adults. Nutrients 10:9, pages 1261.
Crossref
Annhild Mosdøl, Gunn Elisabeth Vist, Camilla Svendsen, Hubert Dirven, Inger Therese Laugsand Lillegaard, Gro Haarklou Mathisen & Trine Husøy. (2018) Hypotheses and evidence related to intense sweeteners and effects on appetite and body weight changes: A scoping review of reviews. PLOS ONE 13:7, pages e0199558.
Crossref
Priscilla Samuel, Keith T Ayoob, Bernadene A Magnuson, Ursula Wölwer-Rieck, Per Bendix Jeppesen, Peter J Rogers, Ian Rowland & Rebecca Mathews. (2018) Stevia Leaf to Stevia Sweetener: Exploring Its Science, Benefits, and Future Potential. The Journal of Nutrition 148:7, pages 1186S-1205S.
Crossref
Maria A. Karalexi, Marina Mitrogiorgou, Georgia G. Georgantzi, Vassiliki Papaevangelou & Smaragdi Fessatou. (2018) Non-Nutritive Sweeteners and Metabolic Health Outcomes in Children: A Systematic Review and Meta-Analysis. The Journal of Pediatrics 197, pages 128-133.e2.
Crossref
Cristian Angel Rosales-Gómez, Beatriz Elina Martínez-Carrillo, Aldo Arturo Reséndiz-Albor, Ninfa Ramírez-Durán, Roxana Valdés-Ramos, Talia Mondragón-Velásquez & Jorge Alberto Escoto-Herrera. (2018) Chronic Consumption of Sweeteners and Its Effect on Glycaemia, Cytokines, Hormones, and Lymphocytes of GALT in CD1 Mice. BioMed Research International 2018, pages 1-15.
Crossref
P. Seferidi, C. Millett & A. A. Laverty. (2018) Sweetened beverage intake in association to energy and sugar consumption and cardiometabolic markers in children. Pediatric Obesity 13:4, pages 195-203.
Crossref
Alyssa Archibald, Vernon Dolinsky & Meghan Azad. (2018) Early-Life Exposure to Non-Nutritive Sweeteners and the Developmental Origins of Childhood Obesity: Global Evidence from Human and Rodent Studies. Nutrients 10:2, pages 194.
Crossref
Liang Chi, Xiaoming Bian, Bei Gao, Pengcheng Tu, Yunjia Lai, Hongyu Ru & Kun Lu. (2018) Effects of the Artificial Sweetener Neotame on the Gut Microbiome and Fecal Metabolites in Mice. Molecules 23:2, pages 367.
Crossref
Rachel Ginieis, Elizabeth A. Franz, Indrawati Oey & Mei Peng. (2018) The “sweet” effect: Comparative assessments of dietary sugars on cognitive performance. Physiology & Behavior 184, pages 242-247.
Crossref
Samuel Durán Agüero, Lissé Angarita Dávila, Ma. Cristina Escobar Contreras, Diana Rojas Gómez & Jorge de Assis Costa. (2018) Noncaloric Sweeteners in Children: A Controversial Theme. BioMed Research International 2018, pages 1-7.
Crossref
Chika Ifeanyi Chukwuma & Md. Shahidul Islam. 2018. Sweeteners. Sweeteners 409 435 .
Qurrat ul-Ain, Madiha Sikander, Sohaib Ahmed Khan, Muhammad Sikander Ghayas Khan & Rabia Ghayas. 2018. Sweeteners. Sweeteners 591 612 .
Jose Manuel García-Almeida, Isabel M. Cornejo-Pareja, Araceli Muñoz-Garach, Ana Gómez-Pérez & Jorge García-Alemán. 2018. Sweeteners. Sweeteners 613 642 .
Szimonetta Lohner, Ingrid Toews & Joerg J. Meerpohl. (2017) Health outcomes of non-nutritive sweeteners: analysis of the research landscape. Nutrition Journal 16:1.
Crossref
Nuala BobowskiJulie A. Mennella. (2017) Personal Variation in Preference for Sweetness: Effects of Age and Obesity. Childhood Obesity 13:5, pages 369-376.
Crossref
Erin Hoare, Pia Varsamis, Neville Owen, David Dunstan, Garry Jennings & Bronwyn Kingwell. (2017) Sugar- and Intense-Sweetened Drinks in Australia: A Systematic Review on Cardiometabolic Risk. Nutrients 9:10, pages 1075.
Crossref
Oliver-John M Bright, Ding Ding Wang, Marissa Shams-White, Sara N Bleich, John Foreyt, Marion Franz, Guy Johnson, Beth Trickett Manning, Rick Mattes, Xavier Pi-Sunyer, Barbara Schneeman, James Scott Parrott, Dan Steffen, Allison Sylvetsky, Paula Ziegler & Mei Chung. (2017) Research Priorities for Studies Linking Intake of Low-Calorie Sweeteners and Potentially Related Health Outcomes. Current Developments in Nutrition 1:7, pages e000547.
Crossref
Xiaoming Bian, Liang Chi, Bei Gao, Pengcheng Tu, Hongyu Ru & Kun Lu. (2017) The artificial sweetener acesulfame potassium affects the gut microbiome and body weight gain in CD-1 mice. PLOS ONE 12:6, pages e0178426.
Crossref
Thea Bjørnland, Mette Langaas, Valdemar Grill & Ingrid Løvold Mostad. (2017) Assessing gene-environment interaction effects of FTO, MC4R and lifestyle factors on obesity using an extreme phenotype sampling design: Results from the HUNT study. PLOS ONE 12:4, pages e0175071.
Crossref
Cinzia Le Donne, Lorenza Mistura, Séverine Goscinny, Steven Janvier, Koenraad Cuypers, Laura D'Addezio, Stefania Sette, Giovina Catasta, Marika Ferrari, Raffaela Piccinelli, Joris Van Loco & Aida Turrini. (2017) Assessment of dietary intake of 10 intense sweeteners by the Italian population. Food and Chemical Toxicology 102, pages 186-197.
Crossref
Maria Carolina Borges, Maria Laura Louzada, Thiago Hérick de Sá, Anthony A. Laverty, Diana C. Parra, Josefa Maria Fellegger Garzillo, Carlos Augusto Monteiro & Christopher Millett. (2017) Artificially Sweetened Beverages and the Response to the Global Obesity Crisis. PLOS Medicine 14:1, pages e1002195.
Crossref
Nuala Bobowski, Danielle R. Reed & Julie A. Mennella. (2016) Variation in the TAS2R31 bitter taste receptor gene relates to liking for the nonnutritive sweetener Acesulfame-K among children and adults. Scientific Reports 6:1.
Crossref
Chika Ifeanyi Chukwuma, Mohammed Auwal Ibrahim & Md. Shahidul Islam. (2016) Myo-inositol inhibits intestinal glucose absorption and promotes muscle glucose uptake: a dual approach study. Journal of Physiology and Biochemistry 72:4, pages 791-801.
Crossref
Peter Spanogiannopoulos, Elizabeth N. Bess, Rachel N. Carmody & Peter J. Turnbaugh. (2016) The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism. Nature Reviews Microbiology 14:5, pages 273-287.
Crossref
Ashleigh E. ReidBhupendrasinh F. Chauhan, Rasheda RabbaniJustin LysLeslie CopsteinAmrinder MannAhmed M. Abou-SettaMichelle FianderDylan S. MacKayJonathan McGavock, Brandy Wicklow, Ryan ZarychanskiMeghan B. Azad. (2016) Early Exposure to Nonnutritive Sweeteners and Long-term Metabolic Health: A Systematic Review. Pediatrics 137:3.
Crossref
P J Rogers, P S Hogenkamp, C de Graaf, S Higgs, A Lluch, A R Ness, C Penfold, R Perry, P Putz, M R Yeomans & D J Mela. (2015) Does low-energy sweetener consumption affect energy intake and body weight? A systematic review, including meta-analyses, of the evidence from human and animal studies. International Journal of Obesity 40:3, pages 381-394.
Crossref
H. Miraji, O. C. Othman, F. N. Ngassapa & E. W. Mureithi. (2016) Research Trends in Emerging Contaminants on the Aquatic Environments of Tanzania. Scientifica 2016, pages 1-6.
Crossref
Chika Ifeanyi Chukwuma & Md. Shahidul Islam. 2017. Fungal Metabolites. Fungal Metabolites 1 27 .
Qurrat ul-Ain, Madiha Sikander, Sohaib Ahmed Khan, Muhammad Sikander Ghayas Khan & Rabia Ghayas. 2017. Sweeteners. Sweeteners 1 23 .
Jose Manuel García-Almeida, Isabel M. Cornejo-Pareja, Araceli Muñoz-Garach, Ana Gómez-Pérez & Jorge García-Alemán. 2017. Sweeteners. Sweeteners 1 30 .
Olivier Bruyère, Serge H. Ahmed, Catherine Atlan, Jacques Belegaud, Murielle Bortolotti, Marie-Chantal Canivenc-Lavier, Sybil Charrière, Jean-Philippe Girardet, Sabine Houdart, Esther Kalonji, Perrine Nadaud, Fabienne Rajas, Gérard Slama & Irène Margaritis. (2015) Review of the nutritional benefits and risks related to intense sweeteners. Archives of Public Health 73:1.
Crossref
Anthony A Laverty, Lucia Magee, Carlos A. Monteiro, Sonia Saxena & Christopher Millett. (2015) Sugar and artificially sweetened beverage consumption and adiposity changes: National longitudinal study. International Journal of Behavioral Nutrition and Physical Activity 12:1.
Crossref
M. Yanina Pepino. (2015) Metabolic effects of non-nutritive sweeteners. Physiology & Behavior 152, pages 450-455.
Crossref
Sofia Charvel, Fernanda Cobo & Mauricio Hernández-Ávila. (2015) A process to establish nutritional guidelines to address obesity: Lessons from Mexico. Journal of Public Health Policy 36:4, pages 426-439.
Crossref
M. Gil-Campos, M.A. San José González & J.J. Díaz Martín. (2015) Uso de azúcares y edulcorantes en la alimentación del niño. Recomendaciones del Comité de Nutrición de la Asociación Española de Pediatría. Anales de Pediatría 83:5, pages 353.e1-353.e7.
Crossref
M. Gil-Campos, M.A. San José González & J.J. Díaz Martín. (2015) Use of sugars and sweeteners in children's diets. Recommendations of the Nutrition Committee of the Spanish Association of Paediatrics. Anales de Pediatría (English Edition) 83:5, pages 353.e1-353.e7.
Crossref
Susan E. Swithers. (2015) Artificial sweeteners are not the answer to childhood obesity. Appetite 93, pages 85-90.
Crossref
John D. Fernstrom. (2015) Non-Nutritive Sweeteners and Obesity. Annual Review of Food Science and Technology 6:1, pages 119-136.
Crossref
Maurissa S.C. Mesirow & Jean A. Welsh. (2015) Changing Beverage Consumption Patterns Have Resulted in Fewer Liquid Calories in the Diets of US Children: National Health and Nutrition Examination Survey 2001-2010. Journal of the Academy of Nutrition and Dietetics 115:4, pages 559-566.e4.
Crossref
Xiaofang Hou, Jing Ma, Xiaoshuang He, Liang Chen, Sicen Wang & Langchong He. (2015) A stop-flow two-dimensional liquid chromatography method for determination of food additives in yogurt. Analytical Methods 7:5, pages 2141-2148.
Crossref
. 2014. Dietary Sugars and Health. Dietary Sugars and Health 116 131 .
Michael I. GoranAllison C. Sylvetsky. 2014. Dietary Sugars and Health. Dietary Sugars and Health 114 129 .
João Ricardo Araújo, Fátima Martel & Elisa Keating. (2014) Exposure to non-nutritive sweeteners during pregnancy and lactation: Impact in programming of metabolic diseases in the progeny later in life. Reproductive Toxicology 49, pages 196-201.
Crossref
Harry Preuss & Jeffrey Preuss. 2014. Metabolic Medicine and Surgery. Metabolic Medicine and Surgery 183 206 .
J. Van Allen, E. S. Kuhl, S. S. Filigno, L. M. Clifford, J. M. Connor & L. J. Stark. (2014) Changes in Parent Motivation Predicts Changes in Body Mass Index z-Score (zBMI) and Dietary Intake Among Preschoolers Enrolled in a Family-Based Obesity Intervention. Journal of Pediatric Psychology 39:9, pages 1028-1037.
Crossref
Paige E Miller & Vanessa Perez. (2014) Low-calorie sweeteners and body weight and composition: a meta-analysis of randomized controlled trials and prospective cohort studies , ,. The American Journal of Clinical Nutrition 100:3, pages 765-777.
Crossref
Ingrid Løvold MostadMette LangaasValdemar Grill. (2014) Central obesity is associated with lower intake of whole-grain bread and less frequent breakfast and lunch: results from the HUNT study, an adult all-population survey. Applied Physiology, Nutrition, and Metabolism 39:7, pages 819-828.
Crossref
Márcio Carocho, Maria Filomena Barreiro, Patricia Morales & Isabel C.F.R. Ferreira. (2014) Adding Molecules to Food, Pros and Cons: A Review on Synthetic and Natural Food Additives. Comprehensive Reviews in Food Science and Food Safety 13:4, pages 377-399.
Crossref
Jing Ma, Bing Zhang, Yunan Wang & Xiaofang Hou. (2013) Comparison of Six Sample Preparation Methods for Analysis of Food Additives in Milk Powder. Food Analytical Methods 7:6, pages 1345-1352.
Crossref
Peter Freswick. (2014) Artificial Sweetened Beverages and Pediatric Obesity: The Controversy Continues. Children 1:1, pages 31-39.
Crossref
Steingerdur Olafsdottir, Gabriele Eiben, Hillevi Prell, Sabrina Hense, Lauren Lissner, Staffan Mårild, Lucia Reisch & Christina Berg. (2013) Young children’s screen habits are associated with consumption of sweetened beverages independently of parental norms. International Journal of Public Health 59:1, pages 67-75.
Crossref
Allison C. Sylvetsky, Mitchell Greenberg, Xiongce Zhao & Kristina I. Rother. (2014) What Parents Think about Giving Nonnutritive Sweeteners to Their Children: A Pilot Study. International Journal of Pediatrics 2014, pages 1-5.
Crossref
John D. Fernstrom. 2014. Fructose, High Fructose Corn Syrup, Sucrose and Health. Fructose, High Fructose Corn Syrup, Sucrose and Health 63 84 .
Sarah French, Michael Rosenberg, Lisa Wood, Clover Maitland, Trevor Shilton, Iain S. Pratt & Peter Buzzacott. (2013) Soft Drink Consumption Patterns Among Western Australians. Journal of Nutrition Education and Behavior 45:6, pages 525-532.
Crossref
Susan E. Swithers. (2013) Artificial sweeteners produce the counterintuitive effect of inducing metabolic derangements. Trends in Endocrinology & Metabolism 24:9, pages 431-441.
Crossref
F. B. Hu. (2013) Resolved: there is sufficient scientific evidence that decreasing sugar-sweetened beverage consumption will reduce the prevalence of obesity and obesity-related diseases. Obesity Reviews 14:8, pages 606-619.
Crossref
N. Peretti. (2013) La consommation de boissons light chez l’enfant. Archives de Pédiatrie 20:6, pages 585-588.
Crossref
Carmen Piernas, Deborah F Tate, Xiaoshan Wang & Barry M Popkin. (2013) Does diet-beverage intake affect dietary consumption patterns? Results from the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial. The American Journal of Clinical Nutrition 97:3, pages 604-611.
Crossref
Sala Horowitz. (2013) Sugar Alternatives and Their Effects on Health. Alternative and Complementary Therapies 19:1, pages 33-39.
Crossref
Anne Raben & Bjørn Richelsen. (2012) Artificial sweeteners. Current Opinion in Clinical Nutrition and Metabolic Care 15:6, pages 597-604.
Crossref
Shu Wen Ng, Meghan M. Slining & Barry M. Popkin. (2012) Use of Caloric and Noncaloric Sweeteners in US Consumer Packaged Foods, 2005-2009. Journal of the Academy of Nutrition and Dietetics 112:11, pages 1828-1834.e6.
Crossref
Allison C Sylvetsky, Jean A Welsh, Rebecca J Brown & Miriam B Vos. (2012) Low-calorie sweetener consumption is increasing in the United States. The American Journal of Clinical Nutrition 96:3, pages 640-646.
Crossref
John D. Fernstrom & Juan L. Navia. (2012) Workshop Summary. The Journal of Nutrition 142:6, pages 1170S-1172S.
Crossref
John Foreyt, Ronald Kleinman, Rebecca J. Brown & Rachel Lindstrom. (2012) The Use of Low-Calorie Sweeteners by Children: Implications for Weight Management. The Journal of Nutrition 142:6, pages 1155S-1162S.
Crossref
Adam Drewnowski, Julie A. Mennella, Susan L. Johnson & France Bellisle. (2012) Sweetness and Food Preference. The Journal of Nutrition 142:6, pages 1142S-1148S.
Crossref
Theodoros Varzakas, Athanasios Labropoulos & Stylianos AnestisTheodoros Varzakas & Costas Chryssanthopoulos. 2012. Sweeteners. Sweeteners 329 366 .
M Maersk, A Belza, J J Holst, M Fenger-Grøn, S B Pedersen, A Astrup & B Richelsen. (2012) Satiety scores and satiety hormone response after sucrose-sweetened soft drink compared with isocaloric semi-skimmed milk and with non-caloric soft drink: a controlled trial. European Journal of Clinical Nutrition 66:4, pages 523-529.
Crossref
Vasanti S. Malik & Frank B. Hu. (2012) Sweeteners and Risk of Obesity and Type 2 Diabetes: The Role of Sugar-Sweetened Beverages. Current Diabetes Reports 12:2, pages 195-203.
Crossref
Tonje H Stea, Nina C Øverby, Knut-Inge Klepp & Elling Bere. (2011) Changes in beverage consumption in Norwegian children from 2001 to 2008. Public Health Nutrition 15:3, pages 379-385.
Crossref
Md. Shahidul Islam & Mitesh Indrajit. (2012) Effects of Xylitol on Blood Glucose, Glucose Tolerance, Serum Insulin and Lipid Profile in a Type 2 Diabetes Model of Rats. Annals of Nutrition and Metabolism 61:1, pages 57-64.
Crossref
Michael W. Roberts & J. Timothy Wright. (2012) Nonnutritive, Low Caloric Substitutes for Food Sugars: Clinical Implications for Addressing the Incidence of Dental Caries and Overweight/Obesity. International Journal of Dentistry 2012, pages 1-8.
Crossref
Jean A. Welsh & Solveig A. Cunningham. (2011) The Role of Added Sugars in Pediatric Obesity. Pediatric Clinics of North America 58:6, pages 1455-1466.
Crossref
Allison Sylvetsky, Kristina I. Rother & Rebecca Brown. (2011) Artificial Sweetener Use Among Children: Epidemiology, Recommendations, Metabolic Outcomes, and Future Directions. Pediatric Clinics of North America 58:6, pages 1467-1480.
Crossref
Lyn O'Brien-NaborsJoan Patton, Beth Hubrich & Lyn Nabors. 2011. Alternative Sweeteners, Fourth Edition. Alternative Sweeteners, Fourth Edition 525 548 .
Marta Y Pepino & Christina Bourne. (2011) Non-nutritive sweeteners, energy balance, and glucose homeostasis. Current Opinion in Clinical Nutrition and Metabolic Care 14:4, pages 391-395.
Crossref
A. Douglas Kinghorn, Li Pan, Joshua N. Fletcher & Heebyung Chai. (2011) The Relevance of Higher Plants in Lead Compound Discovery Programs. Journal of Natural Products 74:6, pages 1539-1555.
Crossref
Pierre Chandon & Brian Wansink. (2011) Is Food Marketing Making Us Fat? A Multi-Disciplinary Review. SSRN Electronic Journal.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.