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Amyotrophic Lateral Sclerosis Volume 11, 2010 - Issue 4
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ORIGINAL ARTICLE

Botulinum toxin type A for the treatment of sialorrhoea in amyotrophic lateral sclerosis: A clinical and neurophysiological study

Francesca Gilio Neurology and Neurophysiopathology Unit, S. Pertini Hospital, Rome, Italy
,
Elisa Iacovelli Department of Neurological Sciences, University of Rome ‘Sapienza’
,
Vittorio Frasca Department of Neurological Sciences, University of Rome ‘Sapienza’
,
Maria Gabriele Department of Neurological Sciences, University of Rome ‘Sapienza’
,
Elena Giacomelli Department of Neurological Sciences, University of Rome ‘Sapienza’
,
Floriana Picchiori Department of Neurological Sciences, University of Rome ‘Sapienza’
,
Pietro Soldo E.N.T. Department, ‘Giorgio Ferreri’ University of Rome ‘Sapienza’
,
Anna Maria Cipriani Neurology and Neurophysiopathology Unit, S. Pertini Hospital, Rome, Italy
,
Giovanni Ruoppolo E.N.T. Department, ‘Giorgio Ferreri’ University of Rome ‘Sapienza’
&
Maurizio Inghilleri Department of Neurological Sciences, University of Rome ‘Sapienza’; S. Raffaele Institute IRCCS, RomeCorrespondence[email protected]
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Pages 359-363 | Received 29 Jun 2009, Accepted 17 Aug 2009, Published online: 25 Nov 2009

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Morten Gersel Stokholm, Carsten Bisgård & Ole Jakob Vilholm. (2013) Safety and administration of treatment with botulinum neurotoxin for sialorrhoea in ALS patients: Review of the literature and a proposal for tailored treatment. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14:7-8, pages 516-520.
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Articles from other publishers (24)

Corrado Pancotti, Giovanni Birolo, Cesare Rollo, Tiziana Sanavia, Barbara Di Camillo, Umberto Manera, Adriano Chiò & Piero Fariselli. (2022) Deep learning methods to predict amyotrophic lateral sclerosis disease progression. Scientific Reports 12:1.
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Eleanor James, Cathy Ellis, Ruth Brassington, Sivakumar Sathasivam & Carolyn A Young. (2022) Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis. Cochrane Database of Systematic Reviews 2022:5.
Crossref
Lindsey Shehee, Ashli O'Rourke & Kendrea L. Garand. (2020) The Role of Radiation Therapy and Botulinum Toxin Injections in the Management of Sialorrhea in Patients With Amyotrophic Lateral Sclerosis: A Systematic Review. Journal of Clinical Neuromuscular Disease 21:4, pages 205-221.
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Lejla Paracka, Katja Kollewe, Martin Klietz, Susanne Petri & Dirk Dressler. (2019) IncobotulinumtoxinA for hypersalivation in patients with amyotrophic lateral sclerosis: an open-label single-centre study. Journal of Neural Transmission 126:10, pages 1341-1345.
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Jin-Sun Jun, Han Gil Seo, Soon-Tae Lee, Kon Chu & Sang Kun Lee. (2017) Botulinum toxin treatment for hypersalivation in anti-NMDA receptor encephalitis. Annals of Clinical and Translational Neurology 4:11, pages 830-834.
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Ton Fang, Felix Jozsa & Ammar Al-Chalabi. 2017. Nonmotor Parkinson’s: The Hidden Face - Management and the Hidden Face of Related Disorders. Nonmotor Parkinson’s: The Hidden Face - Management and the Hidden Face of Related Disorders 1409 1441 .
Martina Petracca, Arianna Guidubaldi, Lucia Ricciardi, Tàmara Ialongo, Alessandra Del Grande, Delia Mulas, Enrico Di Stasio & Anna Rita Bentivoglio. (2015) Botulinum Toxin A and B in sialorrhea: Long-term data and literature overview. Toxicon 107, pages 129-140.
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Domenico Intiso, Mario Basciani, Andrea Santamato, Marta Intiso & Filomena Di Rienzo. (2015) Botulinum Toxin Type A for the Treatment of Neuropathic Pain in Neuro-Rehabilitation. Toxins 7:7, pages 2454-2480.
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Seyed Ehsan Mohammadianynejad, Davood Kashipazha, Afshin Rezazadeh, Mojtaba Khademian Ghadikolaii, Mehdi Masoudi Moqaddam, Shahram Tarahomi, Fatemeh Sadr, Ali Nakhostin Mortazavi & Seyed Navid Naghibi. (2015) The Effect of Botulinum Toxin on the Amount of Sialorrhea in Patients With Neurologic Diseases. Jentashapir Journal of Health Research 6:2.
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Takamura Nagasaka & Yoshihisa Takiyama. 2015. Neurodegenerative Disorders as Systemic Diseases. Neurodegenerative Disorders as Systemic Diseases 237 275 .
Nina Squires, Miles Humberstone, Adrian Wills & Antony Arthur. (2014) The Use of Botulinum Toxin Injections to Manage Drooling in Amyotrophic Lateral Sclerosis/Motor Neurone Disease: A Systematic Review. Dysphagia 29:4, pages 500-508.
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Roisin Lonergan, Hiroshi Mistumoto & Brian Murray. 2014. Neuromuscular Disorders in Clinical Practice. Neuromuscular Disorders in Clinical Practice 395 423 .
G. Ruoppolo, I. Schettino, V. Frasca, E. Giacomelli, L. Prosperini, C. Cambieri, R. Roma, A. Greco, P. Mancini, M. De Vincentiis, V. Silani & M. Inghilleri. (2013) Dysphagia in amyotrophic lateral sclerosis: prevalence and clinical findings. Acta Neurologica Scandinavica 128:6, pages 397-401.
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Anagnostou Evangelos, Rentzos Michael, Alexakis Theodoros, Zouvelou Vasiliki, Zambelis Thomas & Evdokimidis Ioannis. (2013) Volume matters: The influence of different botulinum toxin-A dilutions for sialorrhea in amyotrophic lateral sclerosis. Muscle & Nerve 47:2, pages 276-278.
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Russell B. Smith. (2012) Ultrasound-Guided Procedures for the Office. Ultrasound Clinics 7:2, pages 219-228.
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Peter M. Andersen, Sharon Abrahams, Gian D. Borasio, Mamede de Carvalho, Adriano Chio, Philip Van Damme, Orla Hardiman, Katja Kollewe, Karen E. Morrison, Susanne Petri, Pierre‐Francois Pradat, Vincenzo Silani, Barbara Tomik, Maria Wasner & Markus Weber. (2011) EFNS guidelines on the Clinical Management of Amyotrophic Lateral Sclerosis (MALS) – revised report of an EFNS task force. European Journal of Neurology 19:3, pages 360-375.
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Orla Hardiman, Leonard H. van den Berg & Matthew C. Kiernan. (2011) Clinical diagnosis and management of amyotrophic lateral sclerosis. Nature Reviews Neurology 7:11, pages 639-649.
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Donald J. Crammond. (2011) Neurophysiological mapping of muscle endplate location: Precise targeting improves the efficacy of Botulinum neurotoxin injections. Clinical Neurophysiology 122:8, pages 1487-1489.
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Carolyn A Young, Cathy Ellis, Julia Johnson, Sivakumar Sathasivam & Nicky Pih. (2011) Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis. Cochrane Database of Systematic Reviews.
Crossref
Nathalie GuyNatacha BourryRadhouane DallelChristian DualéPierre VerrelleMichel LapeyrePierre Clavelou. (2011) Comparison of Radiotherapy Types in the Treatment of Sialorrhea in Amyotrophic Lateral Sclerosis. Journal of Palliative Medicine 14:4, pages 391-395.
Crossref
Rebecca Traub, Hiroshi Mitsumoto & Lewis P. Rowland. (2010) Research Advances in Amyotrophic Lateral Sclerosis, 2009 to 2010. Current Neurology and Neuroscience Reports 11:1, pages 67-77.
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Russell B. Smith. (2010) Ultrasound-Guided Procedures for the Office. Otolaryngologic Clinics of North America 43:6, pages 1241-1254.
Crossref
Richard S Bedlack. (2010) Amyotrophic lateral sclerosis: current practice and future treatments. Current Opinion in Neurology 23:5, pages 524-529.
Crossref
. (2010) What's in the Literature?. Journal of Clinical Neuromuscular Disease 12:1, pages 47-54.
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