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Original Article

The use of methylphenidate in paediatric traumatic brain injury

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Pages 15-17 | Accepted 01 Oct 1996, Published online: 10 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Elizabeth Nicholls, Aimee K. Hildenbrand, Richa Aggarwal, Lauren McCarthy & Brian Daly. (2012) The Use of Stimulant Medication to Treat Neurocognitive Deficits in Patients with Pediatric Cancer, Traumatic Brain Injury, and Sickle Cell Disease: A Review. Postgraduate Medicine 124:5, pages 78-90.
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Renske Wassenberg, Jeffrey E. Max, Sharon L. Koele & Kathrina Firme. (2004) Classifying psychiatric disorders after traumatic brain injury and orthopaedic injury in children: adequacy of K-SADS versus CBCL. Brain Injury 18:4, pages 377-390.
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Kerstin Konrad, Siegfried Gauggel, Andrea Manz, Melanie Schöll. (2000) Inhibitory control in children with traumatic brain injury (TBI) and children with attention deficit/hyperactivity disorder (ADHD). Brain Injury 14:10, pages 859-875.
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Articles from other publishers (40)

Eric E. Coris, Byron Moran, Kevin Sneed, Gianluca Del Rossi, Bradford Bindas, Shaan Mehta & Dusty Narducci. (2021) Stimulant Therapy Utilization for Neurocognitive Deficits in Mild Traumatic Brain Injury. Sports Health: A Multidisciplinary Approach 14:4, pages 538-548.
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Hassna Irzan, Marco Pozzi, Nino Chikhladze, Serghei Cebanu, Artashes Tadevosyan, Cornelia Calcii, Alexander Tsiskaridze, Andrew Melbourne, Sandra Strazzer, Marc Modat & Erika Molteni. (2022) Emerging Treatments for Disorders of Consciousness in Paediatric Age. Brain Sciences 12:2, pages 198.
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Michael G. Tramontana, Jonathan W. Prokop, Edwin Williamson, Tara Duffie & Hayden LaFever. (2021) Traumatic Brain Injury-Related Attention Deficits in Children: A Controlled Treatment Trial with Lisdexamfetamine Dimesylate (Vyvanse). Brain Sciences 11:1, pages 117.
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Maria Teresa Lax-Pericall. 2020. Mental Health and Illness of Children and Adolescents. Mental Health and Illness of Children and Adolescents 429 459 .
Maria Teresa Lax-Pericall. 2020. Mental Health and Illness of Children and Adolescents. Mental Health and Illness of Children and Adolescents 1 31 .
Brad G. Kurowski, Jeffery N. Epstein, David W. Pruitt, Paul S. Horn, Mekibib Altaye & Shari L. Wade. (2019) Benefits of Methylphenidate for Long-Term Attention Problems After Traumatic Brain Injury in Childhood: A Randomized, Double-Masked, Placebo-Controlled, Dose-Titration, Crossover Trial. Journal of Head Trauma Rehabilitation 34:2, pages E1-E12.
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Justin R. Davanzo & Shelly D. Timmons. 2018. Controversies in Severe Traumatic Brain Injury Management. Controversies in Severe Traumatic Brain Injury Management 179 190 .
Ozalp Ekinci, Meltem Çobanoğulları Direk, Serkan Gunes, Halenur Teke, Nuran Ekinci, Fatma Yıldırım & Çetin Okuyaz. (2017) Short-term efficacy and tolerability of methylphenidate in children with traumatic brain injury and attention problems. Brain and Development 39:4, pages 327-336.
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Ozalp Ekinci, Meltem Çobanoğullari Direk, Nuran Ekinci & Cetin Okuyaz. (2016) Manic Symptoms Due to Methylphenidate Use in an Adolescent with Traumatic Brain Injury. Clinical Psychopharmacology and Neuroscience 14:3, pages 314-317.
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Nathan K. Evanson, Andrea L. Paulson & Brad G. Kurowski. (2016) A Narrative Review of Pharmacologic and Non-pharmacologic Interventions for Disorders of Consciousness Following Brain Injury in the Pediatric Population. Current Physical Medicine and Rehabilitation Reports 4:1, pages 56-70.
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Catherine J Nikles, Lynne McKinlay, Geoffrey K Mitchell, Sue-Ann S Carmont, Hugh E Senior, Mary-Clare A Waugh, Adrienne Epps, Philip J Schluter & Owen T Lloyd. (2014) Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury – a pilot study. Trials 15:1.
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Barynia Backeljauw & Brad G. Kurowski. (2014) Interventions for Attention Problems After Pediatric Traumatic Brain Injury: What Is the Evidence?. PM&R 6:9, pages 814-824.
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Rafael Pelayo. 2014. Principles and Practice of Pediatric Sleep Medicine. Principles and Practice of Pediatric Sleep Medicine 163 166 .
Percival H. Pangilinan, Angela Giacoletti-Argento, Renee Shellhaas, Edward A. Hurvitz & Joseph Edward Hornyak. (2010) Neuropharmacology in Pediatric Brain Injury: A Review. PM&R 2:12, pages 1127-1140.
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Chong Tae Kim, Elizabeth Moberg-Wolff, Melissa Trovato, Heakyung Kim & Nancy Murphy. (2010) Pediatric Rehabilitation: 1. Common Medical Conditions in Children With Disabilities. PM&R 2:3, pages S3-S11.
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Ronald T. Brown & Brian P. Daly. 2009. Handbook of Clinical Child Neuropsychology. Handbook of Clinical Child Neuropsychology 529 580 .
Gerri Hanten & Harvey S. Levin. 2015. Cognitive Neurorehabilitation. Cognitive Neurorehabilitation 487 506 .
Hossein A. Khalili & Kamyar Keramatian. (2007) Effect of Methylphenidate in Patients with Acute Traumatic Brain Injury; a Randomized Clinical Trial. Progress in Neurotherapeutics and Neuropsychopharmacology 3:01.
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Harvey Levin, Gerri Hanten, Jeffrey Max, Xiaoqi Li, Paul Swank, Linda Ewing-Cobbs, Maureen Dennis, Deleene S. Menefee & Russell Schachar. (2007) Symptoms of Attention-Deficit/Hyperactivity Disorder Following Traumatic Brain Injury in Children. Journal of Developmental & Behavioral Pediatrics 28:2, pages 108-118.
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Lesley Nutton. 2007. Physiotherapy for Children. Physiotherapy for Children 163 184 .
Lisa V. Blitz. 2006. Attention Deficit Disorder. Attention Deficit Disorder 77 84 .
Rob J Forsyth, Beena Jayamoni, Tom C Paine & Sandra Mascarenhas. (2006) Monoaminergic agonists for acute traumatic brain injury. Cochrane Database of Systematic Reviews.
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Houshang Moein, Hossein A. Khalili & Kamyar Keramatian. (2006) Effect of methylphenidate on ICU and hospital length of stay in patients with severe and moderate traumatic brain injury. Clinical Neurology and Neurosurgery 108:6, pages 539-542.
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Yun-Hee Kim, Myoung-Hwan Ko, Seung-Yong Na, Se-Hun Park & Kee-Won Kim. (2016) Effects of single-dose methylphenidate on cognitive performance in patients with traumatic brain injury: a double-blind placebo-controlled study. Clinical Rehabilitation 20:1, pages 24-30.
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Keith Owen Yeates, Kira Armstrong, Jennifer Janusz, H. Gerry Taylor, Shari Wade, Terry Stancin & Dennis Drotar. (2005) Long-Term Attention Problems in Children With Traumatic Brain Injury. Journal of the American Academy of Child & Adolescent Psychiatry 44:6, pages 574-584.
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Brian E. Leonard, Denise McCartan, John White & David J. King. (2004) Methylphenidate: a review of its neuropharmacological, neuropsychological and adverse clinical effects. Human Psychopharmacology: Clinical and Experimental 19:3, pages 151-180.
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Charles Jin & Russell Schachar. (2014) Methylphenidate Treatment of Attention-Defit/Hyperactivity Disorder Secondary to Traumatic Brain Injury: A Critical Appraisal of Treatment Studies. CNS Spectrums 9:3, pages 217-226.
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Kerstin Konrad, Siegfried Gauggel & Josef Schurek. (2003) Catecholamine functioning in children with traumatic brain injuries and children with attention-deficit/hyperactivity disorder. Cognitive Brain Research 16:3, pages 425-433.
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RJ Forsyth, B Jayamoni & TC Paine. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
John Whyte, Monica Vaccaro, Patricia Grieb-Neff & Tessa Hart. (2002) Psychostimulant Use in the Rehabilitation of Individuals with Traumatic Brain Injury. Journal of Head Trauma Rehabilitation 17:4, pages 284-299.
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Peter Weber & Jürg Lütschg. (2002) Methylphenidate treatment. Pediatric Neurology 26:4, pages 261-266.
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A. Febrer Rotger. (2002) Traumatismo craneoencefálico en el niño y adolescente. Rehabilitación 36:6, pages 346-352.
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Judith A. Middleton. (2018) Brain injury in children and adolescents. Advances in Psychiatric Treatment 7:4, pages 257-265.
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Thomas D. Challman & James J. Lipsky. (2000) Methylphenidate: Its Pharmacology and Uses. Mayo Clinic Proceedings 75:7, pages 711-721.
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THOMAS D. CHALLMAN & JAMES J. LIPSKY. (2000) Methylphenidate: Its Pharmacology and Uses. Mayo Clinic Proceedings 75:7, pages 711-721.
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Kathleen Bakker & Mary-Clare Waugh. (2012) Stimulant Use in Paediatric Acquired: Brain Injury: Evaluation of a Protocol. Brain Impairment 1:1, pages 29-36.
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Paramala Janardhanan Santosh & Eric Taylor. (2000) Stimulant drugs. European Child & Adolescent Psychiatry 9:S1, pages S27-S43.
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Anthony E Kline, Hong Q Yan, Juliang Bao, Donald W Marion & C.Edward Dixon. (2000) Chronic methylphenidate treatment enhances water maze performance following traumatic brain injury in rats. Neuroscience Letters 280:3, pages 163-166.
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Elisabeth Guthrie, Joelle Mast, Patricia Richards, Monica McQuaid & Steven Pavlakis. (1999) Traumatic Brain Injury in Children and Adolescents. Child and Adolescent Psychiatric Clinics of North America 8:4, pages 807-826.
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Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow & A. Kluge. 1999. Hagers Handbuch der Pharmazeutischen Praxis. Hagers Handbuch der Pharmazeutischen Praxis 71 233 .

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