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Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration Volume 14, 2013 - Issue sup1
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Research Article

Genetic and epigenetic studies of amyotrophic lateral sclerosis

Ammar Al-ChalabiKing’s College London, Institute of Psychiatry, Department of Clinical Neuroscience, London, UKCorrespondence[email protected]
,
Shin KwakDepartment of Neurology, Center for Disease Biology and Integrative Medicine, The University of Tokyo, Tokyo, Japan
,
Mark MehlerDepartments of Neurology, Neuroscience and Psychiatry, and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York, USA
,
Guy RouleauMontreal Neurological Institute and Hospital, Department of Neurology and Neurosurgery, McGill University, Canada
,
Teepu SiddiqueDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
,
Michael StrongDepartment of Clinical Neurological Sciences, Western University, London, Ontario, Canada
&
Peter Nigel LeighDepartment of Neurology, Brighton and Sussex Medical School, University of Sussex, East Sussex, UK
 show all
Pages 44-52 | Published online: 16 May 2013

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Ali Shojaie, Silvia Rota, Ahmad Al Khleifat, K Ray Chaudhuri & Ammar Al-Chalabi. (2023) Non-motor symptoms in amyotrophic lateral sclerosis: lessons from Parkinson’s disease. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 24:7-8, pages 562-571.
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Articles from other publishers (22)

Guillermo M. Alexander, Terry D. Heiman-Patterson, Frank Bearoff, Roger B. Sher, Laura Hennessy, Shannon Terek, Nicole Caccavo, Gregory A. Cox, Vivek M. Philip & Elizabeth A. Blankenhorn. (2022) Identification of quantitative trait loci for survival in the mutant dynactin p150Glued mouse model of motor neuron disease. PLOS ONE 17:9, pages e0274615.
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Rahul Tripathi, Rohan Gupta, Mehar Sahu, Devesh Srivastava, Ankita Das, Rashmi K Ambasta & Pravir Kumar. (2021) Free radical biology in neurological manifestations: mechanisms to therapeutics interventions. Environmental Science and Pollution Research 29:41, pages 62160-62207.
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Elke Braems, Valérie Bercier, Evelien Van Schoor, Kara Heeren, Jimmy Beckers, Laura Fumagalli, Lieselot Dedeene, Matthieu Moisse, Ilse Geudens, Nicole Hersmus, Arpan R. Mehta, Bhuvaneish T. Selvaraj, Siddharthan Chandran, Ritchie Ho, Dietmar R. Thal, Philip Van Damme, Bart Swinnen & Ludo Van Den Bosch. (2022) HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS. Acta Neuropathologica 144:3, pages 465-488.
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Wolfgang P. Ruf, Eilis Hannon, Axel Freischmidt, Veselin Grozdanov, David Brenner, Kathrin Müller, Antje Knehr, Kornelia Günther, Johannes Dorst, Ole Ammerpohl, Karin M. Danzer, Jonathan Mill, Albert C. Ludolph & Jochen H. Weishaupt. (2022) Methylome analysis of ALS patients and presymptomatic mutation carriers in blood cells. Neurobiology of Aging 116, pages 16-24.
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Masha G. Savelieff, Mohamed H. Noureldein & Eva L. Feldman. 2022. Systems Medicine. Systems Medicine 247 276 .
Balapal S. Basavarajappa & Shivakumar Subbanna. (2021) Histone Methylation Regulation in Neurodegenerative Disorders. International Journal of Molecular Sciences 22:9, pages 4654.
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Francesco Patti, Maria Fiore, Clara G. Chisari, Emanuele D'Amico, Salvatore Lo Fermo, Simona Toscano, Chiara Copat, Margherita Ferrante & Mario Zappia. (2020) CSF neurotoxic metals/metalloids levels in amyotrophic lateral sclerosis patients: comparison between bulbar and spinal onset. Environmental Research 188, pages 109820.
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Marta F. Nabais, Tian Lin, Beben Benyamin, Kelly L. Williams, Fleur C. Garton, Anna A. E. Vinkhuyzen, Futao Zhang, Costanza L. Vallerga, Restuadi Restuadi, Anna Freydenzon, Ramona A. J. Zwamborn, Paul J. Hop, Matthew R. Robinson, Jacob Gratten, Peter M. Visscher, Eilis Hannon, Jonathan Mill, Matthew A. Brown, Nigel G. Laing, Karen A. Mather, Perminder S. Sachdev, Shyuan T. Ngo, Frederik J. Steyn, Leanne Wallace, Anjali K. Henders, Merrilee Needham, Jan H. Veldink, Susan Mathers, Garth Nicholson, Dominic B. Rowe, Robert D. Henderson, Pamela A. McCombe, Roger Pamphlett, Jian Yang, Ian P. Blair, Allan F. McRae & Naomi R. Wray. (2020) Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. npj Genomic Medicine 5:1.
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Sandra Carrera-Juliá, Mari Luz Moreno, Carlos Barrios, Jose Enrique de la Rubia Ortí & Eraci Drehmer. (2020) Antioxidant Alternatives in the Treatment of Amyotrophic Lateral Sclerosis: A Comprehensive Review. Frontiers in Physiology 11.
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Cecilia Garcia, Jose Manuel Vidal-Taboada, Enrique Syriani, Maria Salvado, Miguel Morales & Josep Gamez. (2019) Haplotype Analysis of the First A4V-SOD1 Spanish Family: Two Separate Founders or a Single Common Founder?. Frontiers in Genetics 10.
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Priyam Narain, Ashutosh Pandey, Shruti Gupta, James Gomes, Rohit Bhatia & Perumal Vivekanandan. (2018) Targeted next-generation sequencing reveals novel and rare variants in Indian patients with amyotrophic lateral sclerosis. Neurobiology of Aging 71, pages 265.e9-265.e14.
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Katarina Vrabec, Emanuela Boštjančič, Blaž Koritnik, Lea Leonardis, Leja Dolenc Grošelj, Janez Zidar, Boris Rogelj, Damjan Glavač & Metka Ravnik-Glavač. (2018) Differential Expression of Several miRNAs and the Host Genes AATK and DNM2 in Leukocytes of Sporadic ALS Patients. Frontiers in Molecular Neuroscience 11.
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Paul E. Young, Stephen Kum Jew, Michael E. Buckland, Roger Pamphlett & Catherine M. Suter. (2017) Epigenetic differences between monozygotic twins discordant for amyotrophic lateral sclerosis (ALS) provide clues to disease pathogenesis. PLOS ONE 12:8, pages e0182638.
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Priyam Narain, James Gomes, Rohit Bhatia, Inder Singh & Perumal Vivekanandan. (2017) C9orf72 hexanucleotide repeat expansions and Ataxin 2 intermediate length repeat expansions in Indian patients with amyotrophic lateral sclerosis. Neurobiology of Aging 56, pages 211.e9-211.e14.
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Joanna Czarzasta, Aleksandra Habich, Tomasz Siwek, Adam Czapliński, Wojciech Maksymowicz & Joanna Wojtkiewicz. (2017) Stem cells for ALS: An overview of possible therapeutic approaches. International Journal of Developmental Neuroscience 57:1, pages 46-55.
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F. Bozzo, A. Mirra & M.T. Carrì. (2017) Oxidative stress and mitochondrial damage in the pathogenesis of ALS: New perspectives. Neuroscience Letters 636, pages 3-8.
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M.J. Magnussen & J.D. Glass. 2017. Molecular and Cellular Therapies for Motor Neuron Diseases. Molecular and Cellular Therapies for Motor Neuron Diseases 25 41 .
Benoît Marin, Giancarlo Logroscino, Farid Boumédiene, Anaïs Labrunie, Philippe Couratier, Marie-Claude Babron, Anne Louise Leutenegger, Pierre Marie Preux & Ettore Beghi. (2015) Clinical and demographic factors and outcome of amyotrophic lateral sclerosis in relation to population ancestral origin. European Journal of Epidemiology 31:3, pages 229-245.
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Ximena Paez-Colasante, Claudia Figueroa-Romero, Stacey A. Sakowski, Stephen A. Goutman & Eva L. Feldman. (2015) Amyotrophic lateral sclerosis: mechanisms and therapeutics in the epigenomic era. Nature Reviews Neurology 11:5, pages 266-279.
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Emily F. Mendez & Rita Sattler. (2015) Biomarker development for C9orf72 repeat expansion in ALS. Brain Research 1607, pages 26-35.
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Jeffrey Rosenfeld & Michael J. Strong. (2015) Challenges in the Understanding and Treatment of Amyotrophic Lateral Sclerosis/Motor Neuron Disease. Neurotherapeutics 12:2, pages 317-325.
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Tibor Hortobágyi & Nigel J. Cairns. 2014. Neuropathology of Neurodegenerative Diseases. Neuropathology of Neurodegenerative Diseases 209 248 .

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