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Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration Volume 15, 2014 - Issue 3-4
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Biomarkers

Distinct patterns of cortical atrophy in ALS patients with or without dementia: An MRI VBM study

Venkateswaran RajagopalanDepartment of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA
&
Erik P. PioroNeuromuscular Center and Department of Neurology, Neurological Institute, Cleveland, Ohio, USA;Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USACorrespondence[email protected]
Pages 216-225 | Received 19 Dec 2013, Accepted 20 Dec 2013, Published online: 20 Feb 2014

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Thanuja Dharmadasa, William Huynh, Jun Tsugawa, Yoshimitsu Shimatani, Yan Ma & Matthew C. Kiernan. (2018) Implications of structural and functional brain changes in amyotrophic lateral sclerosis. Expert Review of Neurotherapeutics 18:5, pages 407-419.
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Rebecca Traub & Hiroshi Mitsumoto. (2016) Recent advances and opportunities for improving diagnosis of amyotrophic lateral sclerosis. Expert Opinion on Orphan Drugs 4:9, pages 907-915.
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H. Blasco, P. Vourc’h, P. F. Pradat, P. H. Gordon, C. R. Andres & P. Corcia. (2016) Further development of biomarkers in amyotrophic lateral sclerosis. Expert Review of Molecular Diagnostics 16:8, pages 853-868.
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Articles from other publishers (28)

Yuan Ai, Fei Li, Yanbing Hou, Xiuli Li, Wenbin Li, Kun Qin, Xueling Suo, Du Lei, Huifang Shang & Qiyong Gong. (2023) Differential cortical gray matter changes in early- and late-onset patients with amyotrophic lateral sclerosis. Cerebral Cortex.
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Venkateswaran Rajagopalan & Erik P. Pioro. (2023) Graph network measures reveal distinct white matter abnormalities in motor and extra-motor brain regions of two UMN-predominant ALS subtypes. Journal of the Neurological Sciences, pages 120765.
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Yanying Wang, Dongchao Shen, Bo Hou, Xiaohan Sun, Xunzhe Yang, Jing Gao, Mingsheng Liu, Feng Feng & Liying Cui. (2022) Brain structural and perfusion changes in amyotrophic lateral sclerosis-frontotemporal dementia patients with cognitive and motor onset: a preliminary study. Brain Imaging and Behavior 16:5, pages 2164-2174.
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Venkateswaran Rajagopalan & Erik P. Pioro. (2022) Graph theory network analysis provides brain MRI evidence of a partial continuum of neurodegeneration in patients with UMN-predominant ALS and ALS-FTD. NeuroImage: Clinical 35, pages 103037.
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Elena Ratti, Kimiko Domoto-Reilly, Christina Caso, Alyssa Murphy, Michael Brickhouse, Daisy Hochberg, Nikos Makris, Merit E. Cudkowicz & Bradford C. Dickerson. (2021) Regional prefrontal cortical atrophy predicts specific cognitive-behavioral symptoms in ALS-FTD. Brain Imaging and Behavior 15:5, pages 2540-2551.
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Venkateswaran Rajagopalan & Erik P. Pioro. (2021) Corticospinal Tract and Related Grey Matter Morphometric Shape Analysis in ALS Phenotypes: A Fractal Dimension Study. Brain Sciences 11:3, pages 371.
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Robert Steinbach, Tino Prell, Nayana Gaur, Annekathrin Roediger, Christian Gaser, Thomas E. Mayer, Otto W. Witte & Julian Grosskreutz. (2021) Patterns of grey and white matter changes differ between bulbar and limb onset amyotrophic lateral sclerosis. NeuroImage: Clinical 30, pages 102674.
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Frank Zamudio, Anjanet R. Loon, Shayna Smeltzer, Khawla Benyamine, Nanda K. Navalpur Shanmugam, Nicholas J. F. Stewart, Daniel C. Lee, Kevin Nash & Maj-Linda B. Selenica. (2020) TDP-43 mediated blood-brain barrier permeability and leukocyte infiltration promote neurodegeneration in a low-grade systemic inflammation mouse model. Journal of Neuroinflammation 17:1.
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Ruaridh Cameron Smail & Neil Simon. (2020) Clinical Controversies in Amyotrophic Lateral Sclerosis. EMJ Neurology, pages 80-92.
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Hannelore K. van der BurghHenk-Jan WestenengRenée WalhoutKevin van VeenhuijzenHarold H.G. TanJil M. MeierLeonhard A. BakkerJeroen HendrikseMichael A. van EsJan H. Veldink, Martijn P. van den HeuvelLeonard H. van den Berg. (2020) Multimodal longitudinal study of structural brain involvement in amyotrophic lateral sclerosis. Neurology 94:24.
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Venkateswaran Rajagopalan & Erik P. Pioro. (2019) Unbiased MRI Analyses Identify Micropathologic Differences Between Upper Motor Neuron-Predominant ALS Phenotypes. Frontiers in Neuroscience 13.
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Francesca Trojsi, Giuseppina Caiazzo, Mattia Siciliano, Cinzia Femiano, Carla Passaniti, Antonio Russo, Alvino Bisecco, Maria Rosaria Monsurrò, Mario Cirillo, Fabrizio Esposito, Gioacchino Tedeschi & Gabriella Santangelo. (2019) Microstructural correlates of Edinburgh Cognitive and Behavioural ALS Screen (ECAS) changes in amyotrophic lateral sclerosis. Psychiatry Research: Neuroimaging 288, pages 67-75.
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Jacqueline ChenVolodymyr KostenkoErik P. PioroBruce D. Trapp. (2018) MR Imaging–based Estimation of Upper Motor Neuron Density in Patients with Amyotrophic Lateral Sclerosis: A Feasibility Study. Radiology 287:3, pages 955-964.
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Matthew J. Fogarty. (2018) Driven to decay: Excitability and synaptic abnormalities in amyotrophic lateral sclerosis. Brain Research Bulletin 140, pages 318-333.
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Jinping Xu, Hong Li, Chong Li, Jen-Chih Yao, Jun Hu, Jian Wang, Qingmao Hu, Yuanchao Zhang & Jiuquan Zhang. (2017) Abnormal cortical-basal ganglia network in amyotrophic lateral sclerosis: A voxel-wise network efficiency analysis. Behavioural Brain Research 333, pages 123-128.
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Ana Paula Arantes BuenoMaxime BertouxLeonardo Cruz de SouzaMichael Hornberger. (2017) How predictive are temporal lobe changes of underlying TDP-43 pathology in the ALS-FTD continuum?. Annals of Clinical Neurophysiology 19:2, pages 101.
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Andreas Jeromin & Robert Bowser. 2017. Neurodegenerative Diseases. Neurodegenerative Diseases 491 528 .
Michael Benatar, Kevin Boylan, Andreas Jeromin, Seward B. Rutkove, James Berry, Nazem Atassi & Lucie Bruijn. (2016) ALS biomarkers for therapy development: State of the field and future directions. Muscle & Nerve 53:2, pages 169-182.
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LiQin Sheng, HaiRong Ma, JianGuo Zhong, HuiFang Shang, HaiCun Shi & PingLei Pan. (2015) Motor and extra-motor gray matter atrophy in amyotrophic lateral sclerosis: quantitative meta-analyses of voxel-based morphometry studies. Neurobiology of Aging 36:12, pages 3288-3299.
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Pierre-François Pradat, Edor Kabashi & Claude Desnuelle. (2015) Deciphering spreading mechanisms in amyotrophic lateral sclerosis. Current Opinion in Neurology 28:5, pages 455-461.
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Venkateswaran Rajagopalan & Erik P Pioro. (2015) Comparing brain structural MRI and metabolic FDG-PET changes in patients with ALS-FTD: ‘the chicken or the egg?’ question. Journal of Neurology, Neurosurgery & Psychiatry 86:9, pages 952-958.
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Wenjia Zhu, Xiaoling Fu, Fang Cui, Fei Yang, Yuting Ren, Xiaoyun Zhang, Xiaolan Zhang, Zhaohui Chen, Li Ling & Xusheng Huang. (2015) ALFF Value in Right Parahippocampal Gyrus Acts as a Potential Marker Monitoring Amyotrophic Lateral Sclerosis Progression: a Neuropsychological, Voxel-Based Morphometry, and Resting-State Functional MRI Study. Journal of Molecular Neuroscience 57:1, pages 106-113.
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Martin R. Turner & Esther Verstraete. (2015) What Does Imaging Reveal About the Pathology of Amyotrophic Lateral Sclerosis?. Current Neurology and Neuroscience Reports 15:7.
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Arianna Palmieri, Giovanni Mento, Vincenzo Calvo, Giorgia Querin, Carla D'Ascenzo, Chiara Volpato, Johann Roland Kleinbub, Patrizia Silvia Bisiacchi & Gianni Sorarù. (2015) Female gender doubles executive dysfunction risk in ALS: a case-control study in 165 patients. Journal of Neurology, Neurosurgery & Psychiatry 86:5, pages 574-579.
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Esther Verstraete & Bradley R. Foerster. (2015) Neuroimaging as a New Diagnostic Modality in Amyotrophic Lateral Sclerosis. Neurotherapeutics 12:2, pages 403-416.
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Venkateswaran Rajagopalan & Erik P. Pioro. (2015) Brain Parenchymal Fraction: A Relatively Simple MRI Measure to Clinically Distinguish ALS Phenotypes. BioMed Research International 2015, pages 1-6.
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G. Douaud & M.R. Turner. 2015. Brain Mapping. Brain Mapping 787 797 .
Benjamin Rix Brooks. (2014) ALS-Plus — Where does it begin, where does it end?. Journal of the Neurological Sciences 345:1-2, pages 1-2.
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