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Artificial Cells, Nanomedicine, and Biotechnology
An International Journal
Volume 45, 2017 - Issue 2
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Original Articles

The use of experimental design in the optimization of risperidone biodegradable nanoparticles: in vitro and in vivo study

Ali F. A. AlzubaidiDepartment of Pharmaceutics and Industrial Pharmacy Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia;
,
Abdel-Raheem M. El-HelwDepartment of Pharmaceutics and Industrial Pharmacy Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia;
,
Tarek A. AhmedDepartment of Pharmaceutics and Industrial Pharmacy Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; ;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt;
&
Osama A. A. AhmedDepartment of Pharmaceutics and Industrial Pharmacy Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; ;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Minia University, Minia, EgyptCorrespondence[email protected]
Pages 313-320 | Received 01 Jan 2016, Accepted 25 Jan 2016, Published online: 21 Feb 2016

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Rehab Abdelmonem, Hadel A. Abo El-Enin, Ghada Abdelkader & Mohamed Abdel-Hakeem. (2023) Formulation and characterization of lamotrigine nasal insert targeted brain for enhanced epilepsy treatment. Drug Delivery 30:1.
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Madeleine S. A. Tan, Harendra S Parekh, Preeti Pandey, Dan J. Siskind & James R. Falconer. (2020) Nose-to-brain delivery of antipsychotics using nanotechnology: a review. Expert Opinion on Drug Delivery 17:6, pages 839-853.
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Rajalakshmi Rukmangathen, Indira Muzib Yallamalli & Prasanna Raju Yalavarthi. (2019) Formulation and biopharmaceutical evaluation of risperidone-loaded chitosan nanoparticles for intranasal delivery. Drug Development and Industrial Pharmacy 45:8, pages 1342-1350.
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Samane Bayrami, Zahra Esmaili, SeyedAhmad SeyedAlinaghi, Saeed Reza Jamali Moghadam, Sepide Bayrami, Hamid Akbari Javar, Morteza Rafiee Tehrani & Farid Abedin Dorkoosh. (2019) Fabrication of long-acting insulin formulation based on poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanoparticles: preparation, optimization, characterization, and in vitro evaluation. Pharmaceutical Development and Technology 24:2, pages 176-188.
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Nika Bahari Javan, Leila Rezaie Shirmard, Nersi Jafary Omid, Hamid Akbari Javar, Morteza Rafiee Tehrani & Farid Abedin Dorkoosh. (2016) Preparation, statistical optimisation and in vitro characterisation of poly (3-hydroxybutyrate-co-3-hydroxyvalerate)/poly (lactic-co-glycolic acid) blend nanoparticles for prolonged delivery of teriparatide. Journal of Microencapsulation 33:5, pages 460-474.
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Articles from other publishers (11)

Marwa H. Abdallah, Hemat El-Sayed El-Horany, Hanan M. El-Nahas & Tarek M. Ibrahim. (2023) Tailoring Risperidone-Loaded Glycethosomal In Situ Gels Using Box–Behnken Design for Treatment of Schizophrenia-Induced Rats via Intranasal Route. Pharmaceutics 15:11, pages 2521.
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Shaymaa Wagdy El-Far, Hadel A. Abo El-Enin, Ebtsam M. Abdou, Ola Elsayed Nafea & Rehab Abdelmonem. (2022) Targeting Colorectal Cancer Cells with Niosomes Systems Loaded with Two Anticancer Drugs Models; Comparative In Vitro and Anticancer Studies. Pharmaceuticals 15:7, pages 816.
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Annu, Sanjula Baboota & Javed Ali. (2021) In vitro appraisals and ex vivo permeation prospect of chitosan nanoparticles designed for schizophrenia to intensify nasal delivery. Polymer Bulletin 79:4, pages 2263-2285.
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Hadel A. Abo El-Enin, Rasha E. Mostafa, Marwa F. Ahmed, Ibrahim A. Naguib, Mohamed A. Abdelgawad, Mohammed M. Ghoneim & Ebtsam M. Abdou. (2022) Assessment of Nasal-Brain-Targeting Efficiency of New Developed Mucoadhesive Emulsomes Encapsulating an Anti-Migraine Drug for Effective Treatment of One of the Major Psychiatric Disorders Symptoms. Pharmaceutics 14:2, pages 410.
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Maria Camilla Bergonzi, Anna Rita Bilia & Elisa Landucci. (2022) Applications of innovative technologies to the delivery of antipsychotics. Drug Discovery Today 27:2, pages 401-421.
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Yana Zorkina, Olga Abramova, Valeriya Ushakova, Anna Morozova, Eugene Zubkov, Marat Valikhov, Pavel Melnikov, Alexander Majouga & Vladimir Chekhonin. (2020) Nano Carrier Drug Delivery Systems for the Treatment of Neuropsychiatric Disorders: Advantages and Limitations. Molecules 25:22, pages 5294.
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Allan Radaic & Daniel Martins-de-Souza. (2020) The state of the art of nanopsychiatry for schizophrenia diagnostics and treatment. Nanomedicine: Nanotechnology, Biology and Medicine 28, pages 102222.
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Hibah M. Aldawsari, Usama A. Fahmy, Fathy Abd-Allah & Osama A. A. Ahmed. (2020) Formulation and Optimization of Avanafil Biodegradable Polymeric Nanoparticles: A Single-Dose Clinical Pharmacokinetic Evaluation. Pharmaceutics 12:6, pages 596.
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Lamya H. Al-Wahaibi, Muneera S. M. Al-Saleem, Osama A. A. Ahmed, Usama A. Fahmy, Nabil A. Alhakamy, Basma G. Eid, Ashraf B. Abdel-Naim, Wael M. Abdel-Mageed, Maha M. AlRasheed & Gamal A. Shazly. (2020) Optimized Conjugation of Fluvastatin to HIV-1 TAT Displays Enhanced Pro-Apoptotic Activity in HepG2 Cells. International Journal of Molecular Sciences 21:11, pages 4138.
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Annu, Saleha Rehman, Shadab Md, Sanjula Baboota & Javed Ali. (2019) Analyzing Nanotheraputics-Based Approaches for the Management of Psychotic Disorders. Journal of Pharmaceutical Sciences 108:12, pages 3757-3768.
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Osama A. A. Ahmed. (2018) Development and single dose clinical pharmacokinetics investigation of novel zein assisted- alpha lipoic acid nanoencapsulation of vardenafil. Scientific Reports 8:1.
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