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Scandinavian Journal of Infectious Diseases Volume 12, 1980 - Issue 3
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Dicloxacillin and Flucloxacillin Twice Daily with Probenecid in Staphylococcal Infections: A Clinical and Pharmakokinetic Evaluation

Sven Åke Hedström Departments of Infectious Diseases and Medical Microbiology, University of Lund, Lund, Sweden
&
Gunnar Kahlmeter Departments of Infectious Diseases and Medical Microbiology, University of Lund, Lund, Sweden
Pages 221-225 | Published online: 02 Jan 2015

Citations (16)

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Read on this site (2)

Sven Åke Hedström. (1985) Treatment and Prevention of Recurrent Staphylococcal Furunculosis: Clinical and Bacteriological Follow-up. Scandinavian Journal of Infectious Diseases 17:1, pages 55-58.
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Tom Bergan & Carl Erik Nord. (1984) Recent Advances in Beta-lactam Antibiotics: A Symposium Held at the Soria Moria Conference Center, Oslo, Norway, February 24–25, 1984. Scandinavian Journal of Infectious Diseases 16:sup42, pages 1-176.
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Articles from other publishers (14)

Richard C Wilson, Paul Arkell, Alaa Riezk, Mark Gilchrist, Graham Wheeler, William Hope, Alison H Holmes & Timothy M Rawson. (2022) Addition of probenecid to oral β-lactam antibiotics: a systematic review and meta-analysis. Journal of Antimicrobial Chemotherapy 77:9, pages 2364-2372.
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Philip G. Drennan, Jared K. Green, Sharon J. Gardiner, Sarah C. L. Metcalf, Carl M. J. Kirkpatrick, Richard J. Everts, Mei Zhang & Stephen T. Chambers. (2021) Population pharmacokinetics of free flucloxacillin in patients treated with oral flucloxacillin plus probenecid. British Journal of Clinical Pharmacology 87:12, pages 4681-4690.
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Xuan Yu, Zixuan Chu, Jian Li, Rongrong He, Yaya Wang & Chen Cheng. (2021) Pharmacokinetic Drug-drug Interaction of Antibiotics Used in Sepsis Care in China. Current Drug Metabolism 22:1, pages 5-23.
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Staffan Tevell & Bertil Christensson. (2020) Oral Flucloxacillin for Staphylococcal Osteomyelitis: Obsolete or Underused?. Journal of Bone and Joint Infection 5:1, pages 25-27.
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Richard J. Everts, Ronald Begg, Sharon J. Gardiner, Mei Zhang, John Turnidge, Stephen T. Chambers & Evan J. Begg. (2020) Probenecid and food effects on flucloxacillin pharmacokinetics and pharmacodynamics in healthy volunteers. Journal of Infection 80:1, pages 42-53.
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Mei Zhang, Grant A. Moore, Paul K. L. ChinRichard EvertsEvan J. Begg. (2018) Simultaneous Determination of Cefalexin, Cefazolin, Flucloxacillin, and Probenecid by Liquid Chromatography–Tandem Mass Spectrometry for Total and Unbound Concentrations in Human Plasma. Therapeutic Drug Monitoring 40:6, pages 682-692.
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Sharon J. Gardiner, Philip G. Drennan, Ronald Begg, Mei Zhang, Jared K. Green, Heather L. Isenman, Richard J. Everts, Stephen T. Chambers & Evan J. Begg. (2018) In healthy volunteers, taking flucloxacillin with food does not compromise effective plasma concentrations in most circumstances. PLOS ONE 13:7, pages e0199370.
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Cornelia B. Landersdorfer, Carl M. J. Kirkpatrick, Martina Kinzig, Jürgen B. Bulitta, Ulrike Holzgrabe & Fritz Sörgel. (2008) Inhibition of flucloxacillin tubular renal secretion by piperacillin. British Journal of Clinical Pharmacology 66:5, pages 648-659.
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J. Gath, B. Charles, J. Sampson & B. Smithurst. (2013) Pharmacokinetics and Bioavailability of Flucloxacillin in Elderly Hospitalized Patients. The Journal of Clinical Pharmacology 35:1, pages 31-36.
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Michael R. Krogsgaard, Bjørn Asser Hanson, Torsten Slotsbjerg & Pia Jensen. (2009) Should Probenecid be Used to Reduce the Dicloxacillin Dosage in Orthopaedic Infections? A Study of the Dicloxacillin‐Saving Effect of Probenecid. Pharmacology & Toxicology 74:3, pages 181-184.
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Sven Bergdahl, Margareta Eriksson, Yigael Finkel & Karin Lännergren. (2009) Oral Absorption of Flucloxacillin in Infants and Young Children. Acta Pharmacologica et Toxicologica 58:4, pages 255-258.
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Sven Åke Hedström. (2015) Treatment and Prevention of Recurrent Staphylococcal Furunculosis: Clinical and Bacteriological Follow-up. Archives Internationales de Physiologie 17:1, pages 55-58.
Crossref
P. Anderson, G. Bluhm, M. Ehrnebo, L. Herngren & B. Jacobson. (1985) Pharmacokinetics and distribution of flucloxacillin in pacemaker patients. European Journal of Clinical Pharmacology 27:6, pages 713-719.
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Dennis A Conrad & Melvin I Marks. (1984) Oral Therapy for Orthopedic Infections in Children and Adults. Orthopedics 7:10, pages 1585-1591.
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