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Modern Rheumatology Volume 16, 2006 - Issue 3
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REVIEW ARTICLE

Fractalkine in rheumatoid arthritis and allied conditions

Hisanori UmeharaDivision of Hematology and Immunology, Department of Internal Medicine, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, JapanCorrespondence[email protected]
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Masao TanakaDivision of Hematology and Immunology, Department of Internal Medicine, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan;Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan
,
Toshioki SawakiDivision of Hematology and Immunology, Department of Internal Medicine, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
,
Zhe-Xiong JinDivision of Hematology and Immunology, Department of Internal Medicine, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
,
Cheng-Ri HuangDivision of Hematology and Immunology, Department of Internal Medicine, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
,
Lingli DongDivision of Hematology and Immunology, Department of Internal Medicine, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
,
Takafumi KawanamiDivision of Hematology and Immunology, Department of Internal Medicine, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
,
Hiromi KarasawaDivision of Hematology and Immunology, Department of Internal Medicine, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
,
Yasufumi MasakiDivision of Hematology and Immunology, Department of Internal Medicine, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
,
Toshihiro FukushimaDivision of Hematology and Immunology, Department of Internal Medicine, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
,
Yuko HiroseDivision of Hematology and Immunology, Department of Internal Medicine, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
&
Toshirou OkazakiDepartment of Clinical Laboratory, Medicine/Hematology, Faculty of Medicine, Tottori University, Tottori, Japan
 show all
Pages 124-130 | Received 24 Feb 2006, Accepted 14 Mar 2006, Published online: 02 Jan 2014

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Yoshiya Tanaka, Tsutomu Takeuchi, Hisanori Umehara, Toshihiro Nanki, Nobuyuki Yasuda, Fumitoshi Tago, Makoto Kawakubo, Yasumi Kitahara, Seiichiro Hojo, Tetsu Kawano & Toshio Imai. (2018) Safety, pharmacokinetics, and efficacy of E6011, an antifractalkine monoclonal antibody, in a first-in-patient phase 1/2 study on rheumatoid arthritis. Modern Rheumatology 28:1, pages 58-65.
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Toshihiro Nanki, Toshio Imai & Shinichi Kawai. (2017) Fractalkine/CX3CL1 in rheumatoid arthritis. Modern Rheumatology 27:3, pages 392-397.
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Alia M. Aldahlawi, Mohammed F. Elshal, Fai T. Ashgan & Sami Bahlas. (2015) Chemokine receptors expression on peripheral CD4-lymphocytes in rheumatoid arthritis: Coexpression of CCR7 and CD95 is associated with disease activity. Saudi Journal of Biological Sciences 22:4, pages 453-458.
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Piotr Wojdasiewicz, ?ukasz A. Poniatowski, Andrzej Kotela, Jaros?aw Deszczy?ski, Ireneusz Kotela & Dariusz Szukiewicz. (2014) The Chemokine CX3CL1 (Fractalkine) and its Receptor CX3CR1: Occurrence and Potential Role in Osteoarthritis. Archivum Immunologiae et Therapiae Experimentalis 62:5, pages 395-403.
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Xinghua Guo, Yunfeng Pan, Chuyin Xiao, Yuqiong Wu, Daozhang Cai & Jieruo Gu. (2012) Fractalkine stimulates cell growth and increases its expression via NF ‐κ B pathway in RA ‐ FLS . International Journal of Rheumatic Diseases 15:3, pages 322-329.
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William T. Cefalu. (2011) Fractalkine: A Cellular Link Between Adipose Tissue Inflammation and Vascular Pathologies. Diabetes 60:5, pages 1380-1382.
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Hirokazu Sawai, Yong W. Park, Xiaowen He, Jörg J. Goronzy & Cornelia M. Weyand. (2007) Fractalkine mediates T cell–dependent proliferation of synovial fibroblasts in rheumatoid arthritis. Arthritis & Rheumatism 56:10, pages 3215-3225.
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