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Modern Rheumatology Volume 20, 2010 - Issue 1
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ORIGINAL ARTICLE

Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis

Reiji HigashiyamaDivision of Arthritis Research, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA;Department of Systems BioMedicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan;Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
,
Shigeru MiyakiDivision of Arthritis Research, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
,
Satoshi YamashitaDepartment of Systems BioMedicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan
,
Teruhito YoshitakaDepartment of Systems BioMedicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan
,
Görel LindmanDepartment of Systems BioMedicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan
,
Yoshiaki ItoDepartment of Systems BioMedicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan
,
Takahisa SashoDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
,
Kazuhisa TakahashiDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
,
Martin LotzDivision of Arthritis Research, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
&
Hiroshi AsaharaDivision of Arthritis Research, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA;Department of Systems BioMedicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, JapanCorrespondence[email protected]
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Pages 11-17 | Received 03 Apr 2009, Accepted 05 Aug 2009, Published online: 02 Jan 2014

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Jie Shen, Yousef Abu-Amer, Regis J. O’Keefe & Audrey McAlinden. (2017) Inflammation and epigenetic regulation in osteoarthritis. Connective Tissue Research 58:1, pages 49-63.
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Gun-Il Im & You-Jeong Choi. (2013) Epigenetics in osteoarthritis and its implication for future therapeutics. Expert Opinion on Biological Therapy 13:5, pages 713-721.
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Articles from other publishers (57)

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Yizhuo Wang, Rishika Abrol, Jeffrey Y. W. Mak, Kaustav Das Gupta, Divya Ramnath, Denuja Karunakaran, David P. Fairlie & Matthew J. Sweet. (2022) Histone deacetylase 7: a signalling hub controlling development, inflammation, metabolism and disease. The FEBS Journal 290:11, pages 2805-2832.
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Yitong Zhao, Yuanxu Guo, Mengyao Sun, Safdar Hussion, Ying Zheng, Huang Huang, Xinyu Huo, Yutong Zhao, Fujun Zhang, Yan Han, Qilan Ning, Peng Xu, Jian Sun & Shemin Lu. (2022) Selenium-sensitive histone deacetylase 2 is required for forkhead box O3A and regulates extracellular matrix metabolism in cartilage. Journal of Bone and Mineral Metabolism 40:6, pages 914-926.
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Hope C. Ball, Andrew L. Alejo, Trinity K. Samson, Amanda M. Alejo & Fayez F. Safadi. (2022) Epigenetic Regulation of Chondrocytes and Subchondral Bone in Osteoarthritis. Life 12:4, pages 582.
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Xing Xin, Qizhao Tan, Fang Li, Zhongqiang Chen, Ke Zhang, Feng Li, Bin Yang, Zhili Xing, Fang Zhou, Yun Tian, Yang Lv & Tengjiao Zhu. (2021) Potential Value of Matrix Metalloproteinase-13 as a Biomarker for Osteoarthritis. Frontiers in Surgery 8.
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Qichan Hu & Melanie Ecker. (2021) Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis. International Journal of Molecular Sciences 22:4, pages 1742.
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Qiang Zhang, Zhengxiao Ouyang, Xiaoxia song, Wei Zhu, Xinqiao Tang, Zhong Liu & Xiaoming Chen. (2021) Epigenetic modifications of tumor necrosis factor-alpha in joint cartilage tissue from osteoarthritis patients - CONSORT. Medicine 100:51, pages e27868.
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N. Altorok, V. Nagaraja & B. Kahaleh. 2021. Medical Epigenetics. Medical Epigenetics 251 278 .
Fiorella Carla Grandi & Nidhi Bhutani. (2020) Epigenetic Therapies for Osteoarthritis. Trends in Pharmacological Sciences 41:8, pages 557-569.
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Sarah Kim, Eugenie Macfarlane, Markus J. Seibel & Hong Zhou. 2020. Encyclopedia of Bone Biology. Encyclopedia of Bone Biology 718 725 .
Dongyeon J. Kim, Jun Ying & Jie Shen. 2020. Encyclopedia of Bone Biology. Encyclopedia of Bone Biology 658 675 .
Anwar Fathollahi, Saeed Aslani, Ahmadreza Jamshidi & Mahdi Mahmoudi. (2019) Epigenetics in osteoarthritis: Novel spotlight. Journal of Cellular Physiology 234:8, pages 12309-12324.
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Wenting Liao, Jiadong Sun, Wenjing Liu, Wenyu Li, Jiaxin Jia, Farong Ou, Kai Su, Youhua Zheng, Zhiguang Zhang & Yangpeng Sun. (2018) HDAC10 upregulation contributes to interleukin 1β‐mediated inflammatory activation of synovium‐derived mesenchymal stem cells in temporomandibular joint. Journal of Cellular Physiology 234:8, pages 12646-12662.
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Chengyun Zhang, Zhiqi Zhang, Zongkun Chang, Guping Mao, Shu Hu, Anyu Zeng & Ming Fu. (2019) miR‐193b‐5p regulates chondrocytes metabolism by directly targeting histone deacetylase 7 in interleukin‐1β‐induced osteoarthritis. Journal of Cellular Biochemistry 120:8, pages 12775-12784.
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Bora Faulkner, Kristina Astleford & Kim Mansky. (2019) Regulation of Osteoclast Differentiation and Skeletal Maintenance by Histone Deacetylases. Molecules 24:7, pages 1355.
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Li-xue Zou, Ling Yu, Xun-ming Zhao, Jun Liu, Hou-gen Lu, Gai-wei Liu & Wei-chun Guo. (2019) MiR-375 Mediates Chondrocyte Metabolism and Oxidative Stress in Osteoarthritis Mouse Models through the JAK2/STAT3 Signaling Pathway. Cells Tissues Organs 208:1-2, pages 13-24.
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Yiping Mu, Wei Hao & Songbai Li. (2019) Casticin protects against IL-1β-induced inflammation in human osteoarthritis chondrocytes. European Journal of Pharmacology 842, pages 314-320.
Crossref
Mingcai Zhang, Caleb Grote & Jinxi Wang. 2019. Prognostic Epigenetics. Prognostic Epigenetics 245 268 .
P. Castro-Santos & R. Díaz-Peña. 2019. Pharmacoepigenetics. Pharmacoepigenetics 587 596 .
Norma Celia González-Huerta, Verónica Marusa Borgonio-Cuadra, Eugenio Morales-Hernández, Carolina Duarte-Salazar & Antonio Miranda-Duarte. (2018) Vitamin D receptor gene polymorphisms and susceptibility for primary osteoarthritis of the knee in a Latin American population. Advances in Rheumatology 58:1.
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Guping Mao, Shu Hu, Ziji Zhang, Peihui Wu, Xiaoyi Zhao, Ruifu Lin, Weiming Liao & Yan Kang. (2018) Exosomal miR-95-5p regulates chondrogenesis and cartilage degradation via histone deacetylase 2/8. Journal of Cellular and Molecular Medicine 22:11, pages 5354-5366.
Crossref
Jonathan Baker, Adrian M. D. Falconer, David J. Wilkinson, G. Nicholas Europe-Finner, Gary J. Litherland & Andrew D. Rowan. (2018) Protein kinase D3 modulates MMP1 and MMP13 expression in human chondrocytes. PLOS ONE 13:4, pages e0195864.
Crossref
Saiganesh S.Saathvika R.Udhaya V.Arumugam B.Vishal M.Selvamurugan N.. (2018) Matrix metalloproteinase-13: A special focus on its regulation by signaling cascades and microRNAs in bone. International Journal of Biological Macromolecules 109, pages 338-349.
Crossref
R.H. Brophy, B. Zhang, L. Cai, R.W. Wright, L.J. Sandell & M.F. Rai. (2018) Transcriptome comparison of meniscus from patients with and without osteoarthritis. Osteoarthritis and Cartilage 26:3, pages 422-432.
Crossref
Nazir M. Khan & Tariq M. Haqqi. (2018) Epigenetics in osteoarthritis: Potential of HDAC inhibitors as therapeutics. Pharmacological Research 128, pages 73-79.
Crossref
Pengcheng Wang, Zekai Mao, Qiyong Pan, Rui Lu, Xiaojian Huang, Xiaobin Shang, Rui Zhang & Hongbo You. (2018) Histone deacetylase-4 and histone deacetylase-8 regulate interleukin-1β-induced cartilage catabolic degradation through MAPK/JNK and ERK pathways. International Journal of Molecular Medicine.
Crossref
Patricia Castro-Santos & Roberto Díaz-Peña. (2017) Genomics and epigenomics in rheumatic diseases: what do they provide in terms of diagnosis and disease management?. Clinical Rheumatology 36:9, pages 1935-1947.
Crossref
Tommie C. Simon & Matlock A. Jeffries. (2017) The Epigenomic Landscape in Osteoarthritis. Current Rheumatology Reports 19:6.
Crossref
Wayne Yuk-wai Lee & Bin Wang. (2017) Cartilage repair by mesenchymal stem cells: Clinical trial update and perspectives. Journal of Orthopaedic Translation 9, pages 76-88.
Crossref
G. Mao, Z. Zhang, Z. Huang, W. Chen, G. Huang, F. Meng, Z. Zhang & Y. Kang. (2017) MicroRNA-92a-3p regulates the expression of cartilage-specific genes by directly targeting histone deacetylase 2 in chondrogenesis and degradation. Osteoarthritis and Cartilage 25:4, pages 521-532.
Crossref
Fei Yang, Song Zhou, Chuandong Wang, Yan Huang, Huiwu Li, You Wang, Zhenan Zhu, Jian Tang & Mengning Yan. (2017) Epigenetic modifications of interleukin-6 in synovial fibroblasts from osteoarthritis patients. Scientific Reports 7:1.
Crossref
Odile Gabay & Kathleen A. Clouse. (2016) Épigénétique des maladies du cartilage. Revue du Rhumatisme 83:6, pages 411-414.
Crossref
Odile Gabay & Kathleen A. Clouse. (2016) Epigenetics of cartilage diseases. Joint Bone Spine 83:5, pages 491-494.
Crossref
Chandra K. Singh, Minakshi Nihal & Nihal Ahmad. (2016) Histone Deacetylase Inhibitory Approaches for the Management of Osteoarthritis. The American Journal of Pathology 186:10, pages 2555-2558.
Crossref
Mohammad Shahidul Makki & Tariq M. Haqqi. (2016) Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1β–Induced Matrix Metallopeptidase-13 Expression by Inhibiting IL-6 in Osteoarthritis Chondrocyte. The American Journal of Pathology 186:10, pages 2701-2708.
Crossref
Sergio Portal-Núñez, Pedro Esbrit, María José Alcaraz & Raquel Largo. (2016) Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis. Biochemical Pharmacology 108, pages 1-10.
Crossref
N. Altorok, S. Nada, V. Nagaraja & B. Kahaleh. 2016. Medical Epigenetics. Medical Epigenetics 295 314 .
Kenji Hata. (2015) Epigenetic regulation of chondrocyte differentiation. Japanese Dental Science Review 51:4, pages 105-113.
Crossref
Elizabeth W. Bradley, Lomeli R. Carpio, Andre J. van Wijnen, Meghan E. McGee-Lawrence & Jennifer J. Westendorf. (2015) Histone Deacetylases in Bone Development and Skeletal Disorders. Physiological Reviews 95:4, pages 1359-1381.
Crossref
Mingcai Zhang, Brian Egan & Jinxi Wang. (2015) Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes. The International Journal of Biochemistry & Cell Biology 67, pages 101-109.
Crossref
Hyeonkyeong Kim, Donghyun Kang, Yongsik Cho & Jin-Hong Kim. (2015) Epigenetic Regulation of Chondrocyte Catabolism and Anabolism in Osteoarthritis. Molecules and Cells 38:8, pages 677-684.
Crossref
S. B. Roberts, E. Wootton, L. De Ferrari, O. M. Albagha & D. M. Salter. (2015) Epigenetics of osteoarticular diseases: recent developments. Rheumatology International 35:8, pages 1293-1305.
Crossref
Jinsoo Song, Eun-Heui Jin, Dongkyun Kim, Keun Young Kim, Churl-Hong Chun & Eun-Jung Jin. (2015) MicroRNA-222 regulates MMP-13 via targeting HDAC-4 during osteoarthritis pathogenesis. BBA Clinical 3, pages 79-89.
Crossref
Mingcai Zhang & Jinxi Wang. (2015) Epigenetic regulation of gene expression in osteoarthritis. Genes & Diseases 2:1, pages 69-75.
Crossref
Caroline Ospelt & Steffen Gay. 2015. Rheumatology. Rheumatology 139 144 .
Kun Cao, Lei Wei, Zhiqiang Zhang, Li Guo, Congming Zhang, Yongping Li, Changqi Sun, Xiaojuan Sun, Shaowei Wang, Pengcui Li & Xiaochun Wei. (2014) Decreased histone deacetylase 4 is associated with human osteoarthritis cartilage degeneration by releasing histone deacetylase 4 inhibition of runt-related transcription factor-2 and increasing osteoarthritis-related genes: a novel mechanism of human osteoarthritis cartilage degeneration. Arthritis Research & Therapy 16:6.
Crossref
Jingwei Lu, Ye Sun, Qiting Ge, Huajian Teng & Qing Jiang. (2014) Histone deacetylase 4 alters cartilage homeostasis in human osteoarthritis. BMC Musculoskeletal Disorders 15:1.
Crossref
Melanie R. Shakespear, Daniel M. Hohenhaus, Greg M. Kelly, Nabilah A. Kamal, Praveer Gupta, Larisa I. Labzin, Kate Schroder, Valerie Garceau, Sheila Barbero, Abishek Iyer, David A. Hume, Robert C. Reid, Katharine M. Irvine, David P. Fairlie & Matthew J. Sweet. (2013) Histone Deacetylase 7 Promotes Toll-like Receptor 4-dependent Proinflammatory Gene Expression in Macrophages. Journal of Biological Chemistry 288:35, pages 25362-25374.
Crossref
Emma L WilliamsChristopher J Edwards, Cyrus Cooper & Richard OC Oreffo. (2012) Impact of inflammation on the osteoarthritic niche: implications for regenerative medicine. Regenerative Medicine 7:4, pages 551-570.
Crossref
M.J. Barter, C. Bui & D.A. Young. (2012) Epigenetic mechanisms in cartilage and osteoarthritis: DNA methylation, histone modifications and microRNAs. Osteoarthritis and Cartilage 20:5, pages 339-349.
Crossref
Linda Troeberg & Hideaki Nagase. (2012) Proteases involved in cartilage matrix degradation in osteoarthritis. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1824:1, pages 133-145.
Crossref
Hiroshi Asahara. (2011) Switching gears to an arthritis gene expression network by SirT1 cleavage. Arthritis & Rheumatism 63:8, pages 2161-2163.
Crossref
Leo A B Joosten, Flavio Leoni, Sajeda Meghji & Paolo Mascagni. (2011) Inhibition of HDAC Activity by ITF2357 Ameliorates Joint Inflammation and Prevents Cartilage and Bone Destruction in Experimental Arthritis. Molecular Medicine 17:5-6, pages 391-396.
Crossref
Astrid Jüngel, Caroline Ospelt & Steffen Gay. (2010) What can we learn from epigenetics in the year 2009?. Current Opinion in Rheumatology 22:3, pages 284-292.
Crossref

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