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Modern Rheumatology Volume 20, 2010 - Issue 1
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Original Article

Switching to the anti-interleukin-6 receptor antibody tocilizumab in rheumatoid arthritis patients refractory to antitumor necrosis factor biologics

Shin-ya KawashiriUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
,
Atsushi KawakamiUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
,
Naoki IwamotoUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
,
Keita FujikawaUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
,
Toshiyuki AramakiUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
,
Mami TamaiUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
,
Kazuhiko ArimaUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
,
Kunihiro IchinoseUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
,
Makoto KamachiUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
,
Satoshi YamasakiUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
,
Hideki NakamuraUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
,
Tomoki OriguchiNagasaki University School of Health Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-852, Japan
,
Hiroaki IdaUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
&
Katsumi EguchiUnit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, JapanCorrespondence[email protected]
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Pages 40-45 | Received 11 Mar 2009, Accepted 02 Sep 2009, Published online: 02 Jan 2014

Citations (7)

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Read on this site (4)

Hiroki Wakabayashi, Masahiro Hasegawa, Yosuke Nishioka, Akihiro Sudo & Kusuki Nishioka. (2012) Which subgroup of rheumatoid arthritis patients benefits from switching to tocilizumab versus etanercept after previous infliximab failure? A retrospective study. Modern Rheumatology 22:1, pages 116-121.
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Masahiko Mihara, Yoshiyuki Ohsugi & Tadamitsu Kishimoto. (2011) Tocilizumab, a humanized anti-interleukin-6 receptor antibody, for treatment of rheumatoid arthritis. Open Access Rheumatology: Research and Reviews 3, pages 19-29.
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Shunsuke Mori & Yukitaka Ueki. (2011) Primary lack of efficacy of infliximab therapy for rheumatoid arthritis: pharmacokinetic characterization and assessment of switching to tocilizumab. Modern Rheumatology 21:6, pages 628-636.
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Sally Hamour, Alan D Salama & Charles D Pusey. (2010) Management of ANCA-associated vasculitis: Current trends and future prospects. Therapeutics and Clinical Risk Management 6, pages 253-264.
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Articles from other publishers (3)

Hema Chaplin, Lewis Carpenter, Anni Raz, Elena Nikiphorou, Heidi Lempp & Sam Norton. (2021) Summarizing current refractory disease definitions in rheumatoid arthritis and polyarticular juvenile idiopathic arthritis: systematic review. Rheumatology 60:8, pages 3540-3552.
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Jeroen DeGroot, Anne-Marie Zuurmond & Paul-Peter Tak. 2013. Kelley's Textbook of Rheumatology. Kelley's Textbook of Rheumatology 476 492.e6 .
Regina Rendas-Baum, Gene V Wallenstein, Tamas Koncz, Mark Kosinski, Min Yang, John Bradley & Samuel H Zwillich. (2011) Evaluating the efficacy of sequential biologic therapies for rheumatoid arthritis patients with an inadequate response to tumor necrosis factor-α inhibitors. Arthritis Research & Therapy 13:1.
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