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Modern Rheumatology Volume 20, 2010 - Issue 2
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Original Article

Minimal influence of tocilizumab on IFN-γ synthesis by tuberculosis antigens

Atsushi OgataDepartment of Respiratory Medicine, Allergy and Rheumatic Disease, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, JapanCorrespondence[email protected]
,
Masahide MoriDepartment of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Osaka, Japan
,
Shoji HashimotoDivision of Infection Control and Prevention, Osaka University Hospital, Osaka, Japan
,
Yukihiro YanoDepartment of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Osaka, Japan
,
Takeya FujikawaDepartment of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Osaka, Japan
,
Mari KawaiDepartment of Respiratory Medicine, Allergy and Rheumatic Disease, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan
,
Yusuke KuwaharaDepartment of Respiratory Medicine, Allergy and Rheumatic Disease, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan
,
Toru HiranoDepartment of Respiratory Medicine, Allergy and Rheumatic Disease, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan
,
Junsuke ArimitsuDepartment of Respiratory Medicine, Allergy and Rheumatic Disease, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan
,
Keisuke HagiharaDepartment of Respiratory Medicine, Allergy and Rheumatic Disease, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan
,
Yoshihito ShimaDepartment of Respiratory Medicine, Allergy and Rheumatic Disease, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan
,
Masashi NarazakiDepartment of Respiratory Medicine, Allergy and Rheumatic Disease, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan
,
Souichirou YokotaDepartment of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Osaka, Japan
,
Tadamitsu KishimotoLaboratory of Immune Regulation, Osaka University Graduate School of Frontier Biosciences, Osaka, Japan
,
Ichiro KawaseDepartment of Respiratory Medicine, Allergy and Rheumatic Disease, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan
&
Toshio TanakaDepartment of Respiratory Medicine, Allergy and Rheumatic Disease, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan
 show all
Pages 130-133 | Received 01 Sep 2009, Accepted 01 Oct 2009, Published online: 02 Jan 2014

Citations (18)

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Ying-Ming Chiu & Der-Yuan Chen. (2020) Infection risk in patients undergoing treatment for inflammatory arthritis: non-biologics versus biologics. Expert Review of Clinical Immunology 16:2, pages 207-228.
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Atsushi Ogata, Yasuhiro Kato, Shinji Higa & Kazuyuki Yoshizaki. (2019) IL-6 inhibitor for the treatment of rheumatoid arthritis: A comprehensive review. Modern Rheumatology 29:2, pages 258-267.
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Toshio Tanaka, Yoshihiro Hishitani & Atsushi Ogata. (2014) Monoclonal antibodies in rheumatoid arthritis: comparative effectiveness of tocilizumab with tumor necrosis factor inhibitors. Biologics: Targets and Therapy 8, pages 141-153.
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Masahiko Mihara, Yoshiyuki Ohsugi & Tadamitsu Kishimoto. (2011) Tocilizumab, a humanized anti-interleukin-6 receptor antibody, for treatment of rheumatoid arthritis. Open Access Rheumatology: Research and Reviews 3, pages 19-29.
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Hideko Nakahara, Yosuke Kamide, Yoshimasa Hamano, Takashi Hosokawa, Masayuki Nishide, Yu Lin, Keisuke Kawamoto, Mie Fusama, Shinji Higa, Takashi Kuroiwa, Tsuyoshi Igarashi, Taro Kuritani & Keiji Maeda. (2011) A case report of a patient with rheumatoid arthritis complicated with Mycobacterium avium during tocilizumab treatment. Modern Rheumatology 21:6, pages 655-659.
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Toshio Tanaka, Atsushi Ogata & Masashi Narazaki. (2010) Tocilizumab for the treatment of rheumatoid arthritis. Expert Review of Clinical Immunology 6:6, pages 843-854.
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Articles from other publishers (12)

Joshua S. Davis, David Ferreira, Emma Paige, Craig Gedye & Michael Boyle. (2020) Infectious Complications of Biological and Small Molecule Targeted Immunomodulatory Therapies. Clinical Microbiology Reviews 33:3.
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Gerasimos Evangelatos, Vasiliki Koulouri, Alexios Iliopoulos & George E Fragoulis. (2020) Tuberculosis and targeted synthetic or biologic DMARDs, beyond tumor necrosis factor inhibitors. Therapeutic Advances in Musculoskeletal Disease 12, pages 1759720X2093011.
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Han Joo Baek, Mie Jin Lim, Won Park, Sung Hwan Park, Seung-Cheol Shim, Dae-Hyun Yoo, Hyun Ah Kim, Soo Kon Lee, Yun Jong Lee, Young Eun Park, Hoon-Suk Cha & Yeong-Wook Song. (2019) Efficacy and safety of tocilizumab in Korean patients with active rheumatoid arthritis. The Korean Journal of Internal Medicine 34:4, pages 917-931.
Crossref
Shiang-Fen Huang, Ming-Han Chen, Fu-Der Wang, Chang-Youh Tsai, Chang-Phone Fung & Wei-Juin Su. (2018) Efficacy of isoniazid salvage therapy for latent tuberculosis infection in patients with immune-mediated inflammatory disorders – A retrospective cohort study in Taiwan. Journal of Microbiology, Immunology and Infection 51:6, pages 784-793.
Crossref
Ilaria Sauzullo, Rossana Scrivo, Paola Sessa, Fabio Mengoni, Vincenzo Vullo, Guido Valesini & Claudio Maria Mastroianni. (2018) Changes in T cell effector functions over an 8-year period with TNF antagonists in patients with chronic inflammatory rheumatic diseases. Scientific Reports 8:1.
Crossref
Ching-Tsai Lin, Wen-Nan Huang, Chia-Wei Hsieh, Yi-Ming Chen, Der-Yuan Chen, Tsu-Yi Hsieh & Yi-Hsing Chen. (2017) Safety and effectiveness of tocilizumab in treating patients with rheumatoid arthritis – A three-year study in Taiwan. Journal of Microbiology, Immunology and Infection.
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Atsushi Ogata, Takayoshi Morita, Yuji Yoshida & Toshio Tanaka. (2015) Subcutaneous formulation of tocilizumab for treatment of rheumatoid arthritis. Therapeutic Delivery 6:3, pages 283-295.
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Alejandro Souto, José Ramón Maneiro, Eva Salgado, Loreto Carmona & Juan J. Gomez-Reino. (2014) Risk of tuberculosis in patients with chronic immune-mediated inflammatory diseases treated with biologics and tofacitinib: a systematic review and meta-analysis of randomized controlled trials and long-term extension studies. Rheumatology 53:10, pages 1872-1885.
Crossref
Kevin L. Winthrop & Michael Iseman. (2013) Bedfellows: mycobacteria and rheumatoid arthritis in the era of biologic therapy. Nature Reviews Rheumatology 9:9, pages 524-531.
Crossref
Atsushi OgataToru HiranoYoshihiro HishitaniToshio Tanaka. (2012) Safety and Efficacy of Tocilizumab for the Treatment of Rheumatoid Arthritis. Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders 5, pages CMAMD.S7371.
Crossref
Toshio Tanaka & Tadamitsu Kishimoto. (2012) Immunotherapeutic implication of IL-6 blockade. Immunotherapy 4:1, pages 87-105.
Crossref
Mami INAYAMA, Tsutomu SHINOHARA, Emiko HOSOKAWA, Hisanori MACHIDA, Yoshihito IWAHARA & Fumitaka OGUSHI. (2011) A Case of Pulmonary Nontuberculous Mycobacteriosis Induced by Tocilizumab Treatment for Rheumatoid Arthritis. Kansenshogaku Zasshi 85:5, pages 523-526.
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