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Modern Rheumatology Volume 23, 2013 - Issue 2
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Original Article

A retrospective study of serum KL-6 levels during treatment with biological disease-modifying antirheumatic drugs in rheumatoid arthritis patients: a report from the Ad Hoc Committee for Safety of Biological DMARDs of the Japan College of Rheumatology

Akito TakamuraDepartment of Medicine and Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
,
Shintaro HirataThe First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Japan, Kitakyushu, Japan
,
Hayato NagasawaDepartment of Rheumatology/Clinical Immunology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan
,
Hideto KamedaDivision of Rheumatology and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine, Keio University, Tokyo, Japan
,
Yohei SetoInstitute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan
,
Tatsuya AtsumiDepartment of Internal Medicine II, Graduate School of Medicine, Hokkaido University, Sapporo, Japan
,
Makoto DohiDepartment of Allergy and Rheumatology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
,
Takao KoikeSapporo Medical Center NTT EC, Sapporo, Hokkaido, Japan
,
Nobuyuki MiyasakaDepartment of Medicine and Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan;Department of Pharmacovigilance, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
&
Masayoshi HarigaiDepartment of Medicine and Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan;Global Center of Excellence Program, International Research Center for Molecular Science in Tooth and Bone Diseases, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, JapanCorrespondence[email protected]
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Pages 297-303 | Received 16 Jan 2012, Accepted 19 Apr 2012, Published online: 02 Jan 2014

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Tsutomu Takeuchi, Nobuyuki Miyasaka, Shinichi Kawai, Naonobu Sugiyama, Hirotoshi Yuasa, Noriaki Yamashita, Noriko Sugiyama, Lorin Craig Wagerle, Bonnie Vlahos & Joseph Wajdula. (2015) Pharmacokinetics, efficacy and safety profiles of etanercept monotherapy in Japanese patients with rheumatoid arthritis: review of seven clinical trials. Modern Rheumatology 25:2, pages 173-186.
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Articles from other publishers (10)

Fotios Drakopanagiotakis, Philipp Markart & Paschalis Steiropoulos. (2023) Acute Exacerbations of Interstitial Lung Diseases: Focus on Biomarkers. International Journal of Molecular Sciences 24:12, pages 10196.
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Toshihiko Hoashi, Shun Miyazaki, Saeko Ozaki, Susumu Ichiyama, Michiko Ito, Naoko Kanda & Hidehisa Saeki. (2023) Change in Serum KL-6 Level during Biologic Treatment for Psoriasis. Journal of Nippon Medical School 90:2, pages 194-201.
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Rida Siddique, Malik Hassan Mehmood, Muhammad Haris, Ammara Saleem & Zunera Chaudhry. (2022) Promising role of polymeric nanoparticles in the treatment of rheumatoid arthritis. Inflammopharmacology 30:4, pages 1207-1218.
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Hiroshi Furukawa, Shomi Oka, Takashi Higuchi, Kota Shimada, Atsushi Hashimoto, Toshihiro Matsui & Shigeto Tohma. (2021) Biomarkers for interstitial lung disease and acute-onset diffuse interstitial lung disease in rheumatoid arthritis. Therapeutic Advances in Musculoskeletal Disease 13, pages 1759720X2110225.
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Takashi Ono, Takuya Iwasaki, Yukiko Terada, Kentaro Abe, Jinhee Lee, Manabu Mochizuki & Kazunori Miyata. (2020) Serum KL-6 elevation in a uveitis patient with Behçet's disease treated with adalimumab. American Journal of Ophthalmology Case Reports 18, pages 100660.
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Takuya Masuda, Atsushi Yoshida, Fumiaki Ueno, Shintaro Hara, Haruaki Nabeta, Shotaro Umezawa, Mayuki Shirai, Yoshihide Morikawa, Toshio Morizane, Yutaka Endo & Toshifumi Hibi. (2019) A Patient with KL-6 Elevation with Anti-TNFα Who Could Receive Long-Term Use without Interstitial Pneumonia after Class Switch of Anti-TNFα. Inflammatory Intestinal Diseases 4:1, pages 35-40.
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Masahiro Kamata & Yayoi Tada. (2018) Safety of biologics in psoriasis. The Journal of Dermatology 45:3, pages 279-286.
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Koichi Yanaba, Yoshinori Umezawa, Reiko Sakakihara, Miki Chiba, Toshihiro Ito, Sota Kikuchi, Osamu Fukuchi, Akihiko Asahina, Hidehisa Saeki & Hidemi Nakagawa. (2015) Infliximab and adalimumab, unlike ustekinumab, increase serum KL ‐6 levels in Japanese patients with psoriasis . The Journal of Dermatology 42:8, pages 828-829.
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Atsushi Ogata, Kazuhide Tanimura, Toyohiko Sugimoto, Hiroshi Inoue, Yukitomo Urata, Tsukasa Matsubara, Masakazu Kondo, Yukitaka Ueki, Mitsuhiro Iwahashi, Shigeto Tohma, Shuji Ohta, Yukihiko Saeki & Toshio Tanaka. (2014) Phase III Study of the Efficacy and Safety of Subcutaneous Versus Intravenous Tocilizumab Monotherapy in Patients With Rheumatoid Arthritis. Arthritis Care & Research 66:3, pages 344-354.
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Kenji Takahashi, Hiroshi Nakamura, Kenji Takenouchi, Norishige Iizawa, Masahito Koiwa, Akiko Sato, Yusuke Mochizuki, Hiroshi Watanabe & Shinro Takai. (2014) Serum KL-6 Elevation and Possible Pulmonary Involvement in Patients with Rheumatoid Arthritis Treated with Biological Agents. Journal of Nippon Medical School 81:6, pages 364-371.
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