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Original Article

Using the 21-gene assay to guide adjuvant chemotherapy decision-making in early-stage breast cancer: a cost-effectiveness evaluation in the German setting

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Pages 30-40 | Accepted 16 Aug 2012, Published online: 11 Sep 2012

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Vladislav Berdunov, Steve Millen, Andrew Paramore, Jane Griffin, Sarah Reynia, Nina Fryer, Rebecca Brown & Louise Longworth. (2022) Cost-Effectiveness Analysis of the Oncotype DX Breast Recurrence Score® Test in Node-Negative Early Breast Cancer. ClinicoEconomics and Outcomes Research 14, pages 448-633.
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Articles from other publishers (37)

Felix E. de Jongh, Reva Efe, Kirsten H. Herrmann & Jelle A. Spoorendonk. (2022) Cost and Clinical Benefits Associated with Oncotype DX® Test in Patients with Early-Stage HR+/HER2- Node-Negative Breast Cancer in the Netherlands. International Journal of Breast Cancer 2022, pages 1-12.
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Ramona Erber, Miriam Angeloni, Robert Stöhr, Michael P. Lux, Daniel Ulbrich-Gebauer, Enrico Pelz, Agnes Bankfalvi, Kurt W. Schmid, Robert F. H. Walter, Martina Vetter, Christoph Thomssen, Doris Mayr, Frederick Klauschen, Peter Sinn, Karl Sotlar, Katharina Stering, Albrecht Stenzinger, Marius Wunderle, Peter A. Fasching, Matthias W. Beckmann, Oliver Hoffmann, Rainer Kimmig, Nadia Harbeck, Rachel Wuerstlein, Fulvia Ferrazzi & Arndt Hartmann. (2022) Molecular Subtyping of Invasive Breast Cancer Using a PAM50-Based Multigene Expression Test-Comparison with Molecular-Like Subtyping by Tumor Grade/Immunohistochemistry and Influence on Oncologist’s Decision on Systemic Therapy in a Real-World Setting. International Journal of Molecular Sciences 23:15, pages 8716.
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Rino S. Seedor, Marlana Orloff & Takami Sato. (2021) Genetic Landscape and Emerging Therapies in Uveal Melanoma. Cancers 13:21, pages 5503.
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Bradley M. Turner, Hani Katerji, Huina Zhang & David G. Hicks. (2021) Biomarker and multigene assay testing in ER positive, HER-2 negative breast carcinomas: An international guidelines-based approach. Human Pathology Reports 26, pages 300574.
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Paolo Giorgi Rossi, Annette Lebeau, Carlos Canelo-Aybar, Zuleika Saz-Parkinson, Cecily Quinn, Miranda Langendam, Helen Mcgarrigle, Sue Warman, David Rigau, Pablo Alonso-Coello, Mireille Broeders, Axel Graewingholt, Margarita Posso, Stephen Duffy, Holger J. Schünemann, Mariangela Autelitano, Bettina Borisch, Xavier Castells, Edoardo Colzani, Jan Daneš, Patricia Fitzpatrick, Livia Giordano, Solveig Hofvind, Lydia Ioannidou-Mouzaka, Susan Knox, Lennarth Nystrom, Elena Parmelli, Elsa Perez, Alberto Torresin, Ruben Van Engen, Cary Van Landsveld-Verhoeven & Ken Young. (2021) Recommendations from the European Commission Initiative on Breast Cancer for multigene testing to guide the use of adjuvant chemotherapy in patients with early breast cancer, hormone receptor positive, HER-2 negative. British Journal of Cancer 124:9, pages 1503-1512.
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Yahiya Y. Syed. (2020) Oncotype DX Breast Recurrence Score®: A Review of its Use in Early-Stage Breast Cancer. Molecular Diagnosis & Therapy 24:5, pages 621-632.
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Shahid Ahmed, Sukanya Pati, Duc Le, Kamal Haider & Nayyar Iqbal. (2020) The prognostic and predictive role of 21‐gene recurrence scores in hormone receptor‐positive early‐stage breast cancer. Journal of Surgical Oncology 122:2, pages 144-154.
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Carlo Boeri, Corrado Chiappa, Federica Galli, Valentina De Berardinis, Laura Bardelli, Giulio Carcano & Francesca Rovera. (2020) Machine Learning techniques in breast cancer prognosis prediction: A primary evaluation. Cancer Medicine 9:9, pages 3234-3243.
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Oliver Ibarrondo, Isabel Álvarez-López, Frederick Freundlich, Arantzazu Arrospide, Elena Galve-Calvo, María Gutiérrez-Toribio, Arrate Plazaola & Javier Mar. (2020) Probabilistic cost-utility analysis and expected value of perfect information for the Oncotype multigenic test: a discrete event simulation model. Gaceta Sanitaria 34:1, pages 61-68.
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Sae Byul Lee, Junetae Kim, Guiyun Sohn, Jisun Kim, Il Yong Chung, Hee Jeong Kim, Beom Seok Ko, Byung Ho Son, Sei-Hyun Ahn, Jong Won Lee & Kyung Hae Jung. (2019) A Nomogram for Predicting the Oncotype DX Recurrence Score in Women with T1-3N0-1miM0 Hormone Receptor‒Positive, Human Epidermal Growth Factor 2 (HER2)‒Negative Breast Cancer. Cancer Research and Treatment 51:3, pages 1073-1085.
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Sue Harnan, Paul Tappenden, Katy Cooper, John Stevens, Alice Bessey, Rachid Rafia, Sue Ward, Ruth Wong, Robert C Stein & Janet Brown. (2019) Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: a systematic review and economic analysis. Health Technology Assessment 23:30, pages 1-328.
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Shi-Yi WangWeixiong DangIlana RichmanSarah S. MougalianSuzanne B. EvansCary P. Gross. (2018) Cost-Effectiveness Analyses of the 21-Gene Assay in Breast Cancer: Systematic Review and Critical Appraisal. Journal of Clinical Oncology 36:16, pages 1619-1627.
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Young ChandlerClyde B. SchechterJinani JayasekeraAimee NearSuzanne C. O’NeillClaudine IsaacsCharles E. PhelpsG. Thomas RayTracy A. LieuScott RamseyJeanne S. Mandelblatt. (2018) Cost Effectiveness of Gene Expression Profile Testing in Community Practice. Journal of Clinical Oncology 36:6, pages 554-562.
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E.J. Blok, E. Bastiaannet, W.B. van den Hout, G.J. Liefers, V.T.H.B.M. Smit, J.R. Kroep & C.J.H. van de Velde. (2018) Systematic review of the clinical and economic value of gene expression profiles for invasive early breast cancer available in Europe. Cancer Treatment Reviews 62, pages 74-90.
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Christos Markopoulos. 2018. Breast Cancer Management for Surgeons. Breast Cancer Management for Surgeons 89 101 .
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Jessica G. Cockburn, Robin M. Hallett, Amy E. Gillgrass, Kay N. Dias, T. Whelan, M. N. Levine, John A. Hassell & Anita Bane. (2016) The effects of lymph node status on predicting outcome in ER+ /HER2- tamoxifen treated breast cancer patients using gene signatures. BMC Cancer 16:1.
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Kristen Meldi Plasseraud, Robert W. Cook, Tony Tsai, Yevgeniy Shildkrot, Brooke Middlebrook, Derek Maetzold, Jeff Wilkinson, John Stone, Clare Johnson, Kristen Oelschlager & Thomas M. Aaberg. (2016) Clinical Performance and Management Outcomes with the DecisionDx-UM Gene Expression Profile Test in a Prospective Multicenter Study. Journal of Oncology 2016, pages 1-9.
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Federico Augustovski, Natalie Soto, Joaquín Caporale, Lucas Gonzalez, Luz Gibbons & Agustín Ciapponi. (2015) Decision-making impact on adjuvant chemotherapy allocation in early node-negative breast cancer with a 21-gene assay: systematic review and meta-analysis. Breast Cancer Research and Treatment 152:3, pages 611-625.
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