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Clinical Research

Tourette's syndrome: clinical features, pathophysiology, and therapeutic approaches.

Sindrome de la Tourette: caracteristicas clinicas, fisiopatologia y aproximaciones terapéuticas

Syndrome de Gilles de la Tourette : tableau clinique, physiopathologie et approches thérapeutiques

Pages 161-171 | Published online: 01 Apr 2022

Keep up to date with the latest research on this topic with citation updates for this article.

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Felice Iasevoli, Annarita Barone, Elisabetta Filomena Buonaguro, Licia Vellucci & Andrea de Bartolomeis. (2020) Safety and tolerability of antipsychotic agents in neurodevelopmental disorders: a systematic review. Expert Opinion on Drug Safety 19:11, pages 1419-1444.
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Elif Weidinger, Daniela Krause, Agnes Wildenauer, Sebastian Meyer, Rudolf Gruber, Markus J. Schwarz & Norbert Müller. (2014) Impaired activation of the innate immune response to bacterial challenge in Tourette syndrome. The World Journal of Biological Psychiatry 15:6, pages 453-458.
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Articles from other publishers (23)

Cheng-Hao Huang, Wen-Ling Liao, Der-Yen Lee, I-Ching Chou, Ming-Yu Wang & Ching-Liang Hsieh. (2022) Effects of Yi-Gan-san on the psychiatric behavior of children and adolescents with Tourette's Syndrome: A randomized, double-blind, controlled preliminary study. Journal of Ethnopharmacology 290, pages 115098.
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Davide Martino & James LeckmanYgor Arzeno Ferrão, Pedro Gomes de Alvarenga, Ana Gabriela Hounie, Maria Alice de Mathis, Luis Carlos Farhat, Maria Conceição do Rosário & Eurípedes Constantino Miguel. 2022. Tourette Syndrome. Tourette Syndrome 45 64 .
Calwing Liao, Veikko Vuokila, Hélène Catoire, Fulya Akçimen, Jay P. Ross, Cynthia V. Bourassa, Patrick A. Dion, Inge A. Meijer & Guy A. Rouleau. (2022) Transcriptome-wide association study reveals increased neuronal FLT3 expression is associated with Tourette’s syndrome. Communications Biology 5:1.
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Dr Ranjan Bhattacharyya, Dr Rajarshi Bhadra, Dr Utpal Roy, Dr Sumita Bhattacharyya, Dr Jayanta Pal & Dr Siddhartha Shankar Saha. (2021) Resurgence of Penfluridol: Merits and Demerits. Eastern Journal of Psychiatry 18:1, pages 23-29.
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Joseph Girgis & Tamara Pringsheim. (2020) Prenatal Risk Factors for Tourette Syndrome: a Systematic Review Update. Current Developmental Disorders Reports 7:4, pages 258-269.
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Nermin Eissa, Adel Sadeq, Astrid Sasse & Bassem Sadek. (2020) Role of Neuroinflammation in Autism Spectrum Disorder and the Emergence of Brain Histaminergic System. Lessons Also for BPSD?. Frontiers in Pharmacology 11.
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Thomas Elle, Mesbah Alam, Charlene Voigt, Joachim K. Krauss, Nadine John & Kerstin Schwabe. (2020) Deep brain stimulation of the thalamic centromedian-parafascicular nucleus improves behavioural and neuronal traits in a rat model of Tourette. Behavioural Brain Research 378, pages 112251.
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Danielle Werle, Courtney Byrd, Zoi Gkalitsiou & Kurt Eggers. (2019) Bimanual task performance: Adults who do and do not stutter. Journal of Communication Disorders 81, pages 105911.
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Kerstin Schwabe & Joachim K. Krauss. (2018) What rodent models of deep brain stimulation can teach us about the neural circuit regulation of prepulse inhibition in neuropsychiatric disorders. Schizophrenia Research 198, pages 45-51.
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Shi-Shuang Cui, Ru-Jing Ren, Ying Wang, Gang Wang & Sheng-Di Chen. (2017) Tics as an initial manifestation of juvenile Huntington’s disease: case report and literature review. BMC Neurology 17:1.
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C Wright, J H Shin, A Rajpurohit, A Deep-Soboslay, L Collado-Torres, N J Brandon, T M Hyde, J E Kleinman, A E Jaffe, A J Cross & D R Weinberger. (2017) Altered expression of histamine signaling genes in autism spectrum disorder. Translational Psychiatry 7:5, pages e1126-e1126.
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Shiguo Liu, Mingji Yi, Fengguang Qi, Yuping Sun, Fengyuan Che & Xu Ma. (2011) No significant association between Catechol-O-methyl transferase (COMT) −287A/G gene polymorphism and Tourette’s syndrome in family-based association study in Chinese Han population. European Child & Adolescent Psychiatry 20:11-12, pages 593-596.
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Götz Lütjens, Joachim K. Krauss & Kerstin Schwabe. (2011) Lesions of the entopeduncular nucleus in rats prevent apomorphine-induced deficient sensorimotor gating. Behavioural Brain Research 220:2, pages 281-287.
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Yingfang Tian, Joan R. Gunther, Isaac H. Liao, Dazhi Liu, Bradley P. Ander, Boryana S. Stamova, Lisa Lit, Glen C. Jickling, Huichun Xu, Xinhua Zhan & Frank R. Sharp. (2011) GABA- and acetylcholine-related gene expression in blood correlate with tic severity and microarray evidence for alternative splicing in Tourette syndrome: A pilot study. Brain Research 1381, pages 228-236.
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Yingfang Tian, Isaac H. Liao, Xinhua Zhan, Joan R. Gunther, Bradley P. Ander, Dazhi Liu, Lisa Lit, Glen C. Jickling, Blythe A. Corbett, Netty G.P. Bos-Veneman, Pieter J. Hoekstra & Frank R. Sharp. (2011) Exon expression and alternatively spliced genes in tourette syndrome. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156:1, pages 72-78.
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Isaac H Liao, Blythe A Corbett, Donald L Gilbert, Silvia A Bunge & Frank R Sharp. (2010) Blood gene expression correlated with tic severity in medicated and unmedicated patients with Tourette Syndrome. Pharmacogenomics 11:12, pages 1733-1741.
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Isaac H. Liao & Frank R. Sharp. (2010) Tourette syndrome: Gene expression as a tool to discover drug targets. Neurotherapeutics 7:3, pages 302-306.
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Kirsten Müller‐Vahl, Ines Dodel, Norbert Müller, Alexander Münchau, Jens Peter Reese, Monika Balzer‐Geldsetzer, Richard Dodel & Wolfgang H. Oertel. (2010) Health‐related quality of life in patients with Gilles de la Tourette's syndrome. Movement Disorders 25:3, pages 309-314.
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Anthony L. Rostain. 2010. Handbook of Medical Neuropsychology. Handbook of Medical Neuropsychology 251 273 .
David Pountney. (2009) Identifying and managing Tourette syndrome. British Journal of Neuroscience Nursing 5:9, pages 416-418.
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Ángel Batuecas Caletrío, Fernando Sánchez González, Santiago Santa Cruz Ruiz, Pablo Santos Gorjón & Pedro Blanco Pérez. (2008) Síndrome PANDAS. Acta Otorrinolaringológica Española 59:7, pages 362-363.
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Mauro Porta, Marco Sassi, Mario Cavallazzi, Maurizio Fornari, Arianna Brambilla & Domenico Servello. (2008) Tourette??s Syndrome and Role??of??Tetrabenazine. Clinical Drug Investigation 28:7, pages 443-459.
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Ángel Batuecas Caletrío, Fernando Sánchez González, Santiago Santa Cruz Ruiz, Pablo Santos Gorjón & Pedro Blanco Pérez. (2008) PANDAS Syndrome: ANew Tonsillectomy Indication?. Acta Otorrinolaringologica (English Edition) 59:7, pages 362-363.
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